Protease-Responsive Peptide-Conjugated Mitochondrial-Targeting AIEgens for Selective Imaging and Inhibition of SARS-CoV-2-Infected CellsArticle Published on 2022-08-232022-11-15 Journal: ACS Nano [Category] [DOI] 10.1021/acsnano.2c03219 PMC 바로가기
Anisodamine potently inhibits SARS-CoV-2 infection in vitro and targets its main protease아니소다민은 시험관 내에서 SARS-CoV-2 감염을 강력하게 억제하고 주요 프로테아제를 표적으로 합니다Article Published on 2022-08-062022-09-11 Journal: Biochemical and Biophysical Research Communication [Category] [DOI] 10.1016/j.bbrc.2022.05.024 PMC 바로가기 [Article Type] Article
Discovery of 2-(furan-2-ylmethylene)hydrazine-1-carbothioamide derivatives as novel inhibitors of SARS-CoV-2 main proteaseSARS-CoV-2 주요 프로테아제의 신규 억제제로서의 2-(푸란-2-일메틸렌)히드라진-1-카르보티오아미드 유도체의 발견Article Published on 2022-08-052022-09-11 Journal: European journal of medicinal chemistry [Category] [DOI] 10.1016/j.ejmech.2022.114508 PMC 바로가기 [Article Type] Article
A proteomics-MM/PBSA dual approach for the analysis of SARS-CoV-2 main protease substrate peptide specificitySARS-CoV-2 주요 프로테아제 기질 펩타이드 특이성 분석을 위한 proteomics-MM/PBSA 이중 접근법Article Published on 2022-08-012022-09-11 Journal: Peptides [Category] [DOI] 10.1016/j.peptides.2022.170814 PMC 바로가기 [Article Type] Article
Phytochemical Discrimination, Biological Activity and Molecular Docking of Water-Soluble Inhibitors from Saussurea costus Herb against Main Protease of SARS-CoV-2SARS-CoV-2의 주요 프로테아제에 대한 Saussurea costus Herb의 수용성 억제제의 식물화학적 판별, 생물학적 활성 및 분자 도킹Article Published on 2022-08-012022-09-11 Journal: Molecules [Category] [DOI] 10.3390/molecules27154908 PMC 바로가기 [Article Type] Article
Effect of pH on stability of dimer structure of the main protease of coronavirus-2Article Published on 2022-08-012023-07-09 Journal: Biophysical chemistry [Category] [DOI] 10.1016/j.bpc.2022.106829 PMC 바로가기
A Multistage In Silico Study of Natural Potential Inhibitors Targeting SARS-CoV-2 Main ProteaseSARS-CoV-2 주요 프로테아제를 표적으로 하는 천연 잠재적 억제제에 대한 다단계 인실리코 연구Article Published on 2022-07-292022-09-11 Journal: International Journal of Molecular Sciences [Category] [DOI] 10.3390/ijms23158407 PMC 바로가기 [Article Type] Article
Developing evolution-resistant drugs for COVID-19COVID-19에 대한 진화 내성 약물 개발Editorial Published on 2022-07-262022-09-11 Journal: eLife [Category] [DOI] 10.7554/eLife.81334 PMC 바로가기 [Article Type] Editorial
From Repurposing to Redesign: Optimization of Boceprevir to Highly Potent Inhibitors of the SARS-CoV-2 Main Protease용도 변경에서 재설계까지: SARS-CoV-2 주요 프로테아제의 강력한 억제제에 대한 보세프레비르의 최적화Article Published on 2022-07-042022-09-11 Journal: Molecules [Category] [DOI] 10.3390/molecules27134292 PMC 바로가기 [Article Type] Article
Hydroxamate and thiosemicarbazone: Two highly promising scaffolds for the development of SARS-CoV-2 antivirals하이드록사메이트 및 티오세미카바존: SARS-CoV-2 항바이러스제 개발을 위한 2개의 매우 유망한 스캐폴드Article Published on 2022-07-012022-09-11 Journal: Bioorganic chemistry [Category] [DOI] 10.1016/j.bioorg.2022.105799 PMC 바로가기 [Article Type] Article