The growth factor/cytokine midkine may participate in cytokine storm and contribute to the pathogenesis of severe acute respiratory syndrome coronavirus 2-infected patientsReviews Published on 2021-09-252022-10-31 Journal: The Egyptian Journal of Bronchology [Category] COVID-19, [키워드] acute respiratory syndrome Admission Biomarker caused changes in contribute coronavirus coronavirus disease country COVID-19 COVID-19 patient creating critically ill patients cytokine cytokine level Cytokine storm diagnosed with COVID-19 dramatic increase Effects Endothelial cell Evidence expressed fibrosis growth health system hypoxic conditions increase in Inflammation inflammatory cell Inflammatory diseases information intensive care involved lung Midkine mild illness outbreak overexpressed overexpression pandemic Pathogenesis Patient physiological positive question released reveal SARS-CoV-2 severe respiratory failure tissue repair Treatment protocol Wuhan, China [DOI] 10.1186/s43168-021-00087-6 PMC 바로가기 [Article Type] Reviews
The Association between Vitamin D and Zinc Status and the Progression of Clinical Symptoms among Outpatients Infected with SARS-CoV-2 and Potentially Non-Infected Participants: A Cross-Sectional StudyArticle Published on 2021-09-252022-10-31 Journal: Nutrients [Category] COVID-19, SARS, [키워드] 25-hydroxyvitamin D applied association Asymptomatic clinical clinical symptom Clinical symptoms component Concentration conducted COVID-19 COVID-19 outpatient cross-sectional deficiency disease examined Immunity infected patient Laboratory mild illness moderate non-infected Odds ratio Outpatient participant Participants Patient patients with asymptomatic patients with moderate predict progression pulmonary symptom SARS-CoV-2 serum significantly lower status sunlight exposure Symptom Vitamin D Vitamin D status with COVID-19 Zinc zinc status [DOI] 10.3390/nu13103368 PMC 바로가기 [Article Type] Article
Research on Influencing Factors and Classification of Patients With Mild and Severe COVID-19 SymptomsCellular and Infection Microbiology Published on 2021-08-182022-10-31 Journal: Frontiers in Cellular and Infection Microbiology [Category] COVID-19, MERS, SARS, [키워드] Admission age analyzed average can be used categories changes in city classification clinical characteristic Clinical characteristics clinical symptom Clinical symptoms Cluster complement condition conducted cough COVID-19 COVID-19 cases COVID-19 patient COVID-19 severity D-dimer determine diabete diarrhea Dyspnea Epidemic epidemiological history Factor fatigue females Fever headache Hospital admission Hospital stay hypertension identify illness onset independent predictor indicate Infection infections information Laboratory Laboratory testing laboratory-confirmed Lasso-Logistic regression leukopenia Logistic regression lymphocyte Lymphocyte count lymphopenia male median Mild mild and severe mild illness mild patient mild patients neutrophil Ninth NLR non-specific objective Older other diseases oversampling parameter Patient patients patients with COVID-19 phosphate phosphocreatine predicted procalcitonin random Random forest Research Result Retrospective study Risk factors selected Severe COVID-19 Infection Severe patient severe patients severity severity of COVID-19 significantly subject Symptom the disease the patient Treatment underlying disease variable vomiting [DOI] 10.3389/fcimb.2021.670823 PMC 바로가기 [Article Type] Cellular and Infection Microbiology
Early and High SARS-CoV-2 Neutralizing Antibodies Are Associated with Severity in COVID-19 Patients from India초기 및 높은 SARS-CoV-2 중화 항체는 인도의 COVID-19 환자의 중증도와 관련이 있습니다Article Published on 2021-08-172022-09-12 Journal: The American Journal of Tropical Medicine and Hygi [Category] MERS, SARS, 진단, [키워드] 1:1 association Asymptomatic asymptomatic individual Asymptomatic individuals asymptomatic infection clinical disease Clinical presentations comparable Contact COVID-19 COVID-19 patient defined died disease disease severity examined exhibited fatality females group immune correlates Immunopathogenesis index cases India Live virus male males Mild mild illness mild infections NAb NAb titer NAb titers NAbs neutralization test Neutralizing antibodies neutralizing antibody onset of disease outcome Patient plaque reduction neutralization Plaque reduction neutralization test plasma progression proportion SARS-CoV-2 SARS-COV-2 infection screened Seropositivity serum severe disease severity significantly higher symptomatic infection titers were measured [DOI] 10.4269/ajtmh.21-0014 PMC 바로가기 [Article Type] Article
Comparison of two assays to detect IgG antibodies to the receptor binding domain of SARS‑CoV‑2 as a surrogate marker for assessing neutralizing antibodies in COVID-19 patientsCOVID-19 환자에서 중화 항체를 평가하기 위한 대리 표지자로서 SARS-CoV-2의 수용체 결합 도메인에 대한 IgG 항체를 검출하기 위한 두 가지 분석법의 비교Article Published on 2021-08-012022-09-11 Journal: International Journal of Infectious Diseases [Category] MERS, SARS, 바이오마커, 진단, 치료기술, [키워드] acute illness acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibody Cohort coronavirus correlated COVID-19 COVID-19 patient detect disease severity FIVE Haemagglutination assay IgG antibody Indicator Kinetics marker mild illness moderate NAb NAbs Neutralization assay neutralization test Neutralizing antibodies neutralizing antibody Patient persistence positively correlated Receptor binding domain Reinfection respiratory SARS-CoV-2 sensitivity Seven severe acute respiratory syndrome Coronavirus severity severity of illness significantly Spearman specificity surrogate surrogate neutralization assay surrogate virus neutralization test sVNT titre virus neutralization test were assessed [DOI] 10.1016/j.ijid.2021.06.031 PMC 바로가기 [Article Type] Article
SARS-CoV-2 specific T cell responses are lower in children and increase with age and time after infectionSARS-CoV-2 특이적 T 세포 반응은 소아에서 더 낮고 감염 후 나이와 시간이 지남에 따라 증가합니다Article Published on 2021-07-292022-09-12 Journal: Nature Communications [Category] SARS, 진단, [키워드] adaptive Adults age antibodies B cell response baseline CD4 CD4+ CD8 CD8+ T cell CD8+ T cell response cellular immunity children comparable COVID-19 COVID-19 pathogenesis cytokine Cytokines effector memory examined follicular immune cell response immune cell responses Immunity immunological infected children Infection Inflammation less levels of antibody memory mild illness monocyte ordination ORF1ab Post-infection Protein reduced response SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 protein susceptible T and B cell responses T cell T cell activation T cell response T cell responses Total viral infection β-coronavirus β-Coronaviruses [DOI] 10.1038/s41467-021-24938-4 PMC 바로가기 [Article Type] Article
Case Report of a Saga of Post-COVID-19 ComplicationsInternal Medicine Published on 2021-07-072022-10-31 Journal: Cureus [Category] COVID-19, [키워드] activate acute respiratory syndrome Arthritis cause caused characterized clinical feature Complication complications coronavirus Coronavirus disease 2019 cough COVID-19 COVID-19 pandemic diarrhea Empyema endophthalmitis fatigue Fever headache hospitalized patient immune dysregulation immune system joints knowledge majority mechanical ventilation mild illness myalgias Patient Pneumonia pro-thrombotic report reported Respiratory failure Sepsis severe cases severe COVID-19 sore throat Symptom systemic inflammation thrombosis Treatment virus with COVID-19 [DOI] 10.7759/cureus.16247 PMC 바로가기 [Article Type] Internal Medicine
Isolation of SARS-CoV-2 from the air in a car driven by a COVID patient with mild illness가벼운 질병을 가진 COVID 환자가 운전하는 자동차의 공기에서 SARS-CoV-2의 격리Article Published on 2021-07-012022-09-11 Journal: International Journal of Infectious Diseases [Category] SARS, 치료기술, [키워드] air conditioning cascade completion cough COVID COVID-19 patient detectable determine drive driven by Fever highlight infected with SARS-CoV-2 Mask mild illness Particle Particles Patient PCR potential risk retrieved risk SARS-CoV-2 SARS-CoV-2 aerosols SARS-CoV-2 in vehicles. SARS-CoV-2 transmission Section Stage symptomatic virus windows [DOI] 10.1016/j.ijid.2021.04.063 PMC 바로가기 [Article Type] Article
How and to What Extent Immunological Responses to SARS-CoV-2 Shape Pulmonary Function in COVID-19 PatientsPhysiology Published on 2021-06-292022-10-31 Journal: Frontiers in Physiology [Category] COVID-19, [키워드] Admission caused COVID-19 COVID-19 patient Critical diffusing capacity for lung carbon monoxide disease Factor function ICU immune response mild illness new coronavirus SARS-CoV-2 Perspective Physiology pulmonary Respiratory failure Respiratory function respiratory function testing Respiratory Physiology Respiratory system response SARS-CoV-2 Sery shape Tribute understanding [DOI] 10.3389/fphys.2021.628288 PMC 바로가기 [Article Type] Physiology
Intra-species sialic acid polymorphism in humans: a common niche for influenza and coronavirus pandemics?Review Article Published on 2021-06-142022-10-31 Journal: Emerging Microbes & Infections [Category] COVID-19, SARS, 신종인플루엔자, [키워드] 1918 H1N1 pandemic acute respiratory syndrome Asymptomatic co-evolution confirmed case coronavirus CoV COVID-19 pandemic CoVs death Epidemic Epidemics Evolution Fatality rate General population H1N1 influenza H1N1 pandemic Host impacted infected individual Influenza Influenza and coronavirus Influenza virus mild illness mild symptoms pandemic Pandemics polymorphism receptor recognize severe cases sialic acid sialic acid receptor the United State Variation virus [DOI] 10.1080/22221751.2021.1935329 PMC 바로가기 [Article Type] Review Article