COVID-19 reinfection after pregnancyShort communication Published on 2022-03-012022-10-05 Journal: Infectious diseases now [Category] SARS, 바이오마커, 변종, [키워드] Anomaly Anosmia cough Course COVID-19 CRP elevated Fever Follow-up headache immunological Infection LDH lymphopenia mild infection occurred Pregnancy Reinfection reported rhinorrhea SARS-CoV-2 with COVID-19 [DOI] 10.1016/j.idnow.2022.01.002 [Article Type] Short communication
Efficacy of Favipiravir in treatment of mild & moderate COVID-19 infection in Nepal: a multi-center, randomized, open-labelled, phase III clinical trialConference abstract Published on 2022-03-012022-10-05 Journal: International Journal of Infectious Diseases [Category] 임상, [키워드] adverse events Analysis Clinical improvement clinical trial comparable COVID-19 patient COVID19 Data analysis elevated eligibility criteria enrolled Favipiravir hospital Infection Liver function material Mild mild infection moderate Moderate COVID-19 Nepal onset of symptoms outcome participant Patient Placebo Preliminary data preliminary report Randomized Randomly receiving Remdesivir reported Result RT-PCR Side effect the patient the study group Tolerability Treatment uric acid while [DOI] 10.1016/j.ijid.2021.12.109 [Article Type] Conference abstract
Low Serum Levels of Interferon Alpha in COVID-19 Patients Are Associated with Older AgeArticle Published on 2022-02-122022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] age association circulating Cohort COVID-19 COVID-19 outpatient COVID-19 patient explain IFN IFN response IFNα IFNα immune response Innate intensive care investigated Level mild infection Neutralizing activity Neutralizing antibodies outcome progression reduced SARS-CoV-2 SARS-COV-2 infection serum severe COVID-19 susceptibility type 1 interferon [DOI] 10.3390/jcm11040961 PMC 바로가기 [Article Type] Article
Comprehensive characterization of the antibody responses to SARS-CoV-2 Spike protein finds additional vaccine-induced epitopes beyond those for mild infectionSARS-CoV-2 스파이크 단백질에 대한 항체 반응의 포괄적인 특성화는 경증 감염에 대한 것 이외의 추가 백신 유도 에피토프를 찾습니다.Comparative Study Published on 2022-01-242022-09-10 Journal: eLife [Category] 변종, 치료기술, 치료제, [키워드] Affect affected age Alter Analysis antibodies antibody Antibody binding antibody epitope Antibody Response Antigen Bacteria binding C-terminal domain cause chair changes in complicate Comprehensive computing conserved Control covariate COVID-19 COVID-19 pandemic disease DNA fragment dose education effective epitope Epitopes escape escape mutations experiment exposure to faculty FAM feature finding focus foundation funding fusion peptide genetic code help Howard Hughe Howard Hughes Human Humoral response humoral responses identify immune Immune escape immune system implication individual infect infected individuals Infection Infrastructure interfere Laboratory Lower majority mild infection mRNA vaccination mRNA vaccine mutant Mutation mutations NIH not affect not altered occur offered overlapping pandemic pathway Pathways pattern peptide peptides phage phages population level portion Principal component principal component analysis produced producing PROTECT Protein RBD Region regions Research residue route S1 subunit S2 subunit SARS-CoV-2 SARS-CoV-2 spike protein Scholar selected severe disease Severe infection shape small molecule Small molecules specific antibodies specific protein spike Spike protein spike-specific antibodies Spike-specific antibody Spread stick subsequent Support supported target the antibody the antibody response the RBD the S1 subunit the SARS-CoV-2 the Spike the spike protein thought triggering unique vaccinated individual vaccinated individuals vaccination Vaccine Vaccine development vaccine-induced antibodies vaccine-induced antibody variant Variation virus was performed while wild-type [DOI] 10.7554/eLife.73490 PMC 바로가기 [Article Type] Comparative Study
SARS-CoV-2 Reverse Zoonoses to Pumas and Lions, South AfricaSARS-COV-2 리버스 Zoonose는 남아프리카의 푸마 및 라이온스Article Published on 2022-01-112022-09-10 Journal: Viruses [Category] Fulltext, SARS, 변종, 조류인플루엔자, [키워드] acute respiratory syndrome African animals circulating coronavirus coronavirus 2 delta variant exotic genomic Human Infection mild infection mitigate one health Pathogenesis Pneumonia positive raise remained respiratory reverse zoonosis risk SARS-CoV-2 SARS-CoV-2 RNA Severe acute respiratory syndrome Severe acute respiratory syndrome-related coronavirus severe acute respiratory syndrome-related coronavirus 2 South Africa Surveillance susceptible Transmission Transmission dynamics variant wildlife zookeeper [DOI] 10.3390/v14010120 PMC 바로가기 [Article Type] Article
Clinical profile and outcome of COVID-19 in haematological malignancies: experience from tertiary care centre in IndiaObservational Study Published on 2022-01-012022-10-05 Journal: Annals of Hematology [Category] SARS, 임상, [키워드] 95% CI analysed Analysis Cancer cancers Care clinical coexistent Cohort collected conducted COVID-19 database diagnosed with COVID-19 Evidence Factors haematological malignancies haematological malignancy Hospital admission India Infection Invasive mechanical ventilation log rank mild infection moderate-to-severe COVID-19 Mortality mortality rate North outcome Patient patients patients with haematological Prognosis prospective observational study recruited risk risk factor Risk factors SARS-COV-2 infection severe COVID-19 severity of COVID-19 study period subset [DOI] 10.1007/s00277-021-04644-3 PMC 바로가기 [Article Type] Observational Study
Resolution of viral load in mild COVID-19 patients is associated with both innate and adaptive immune responses경증 COVID-19 환자의 바이러스 부하 해결은 선천 면역 반응 및 적응 면역 반응 모두와 관련이 있습니다Article Published on 2022-01-012022-09-11 Journal: Journal of Clinical Virology [Category] SARS, 변종, 신약개발, 유전자 메커니즘, 진단, 치료기술, [키워드] absence acute phase Adaptive immune response all the patients antibodies antibody Asymptomatic characterized circulating collected Comorbidities Comorbidity COVID-19 COVID-19 patient COVID-19 patients Cytokines detectable dysregulation Efficiency elevated Factor had no hospitalized COVID-19 patient Host IgG IL-1β IL-6 IL-7 IL-8 immune response implicated in viral increase in Inflammation Inflammatory cytokine Inflammatory cytokines inflammatory mediator Inflammatory mediators innate immune response interferon Kinetics marker mediators mild COVID-19 patient mild infection Mild symptom mild symptoms Most patient Most patients neutralize Neutralizing antibodies neutralizing antibody no increase over Patient PRNT Receptor-binding domain Resolution respiratory respiratory sample Respiratory samples Saliva saliva samples SARS-CoV-2 SARS-CoV-2 viral load Seroconversion serum serum samples severe COVID-19 strain swab samples Symptom T-cell activation the patient the receptor-binding domain These data TNF-α Viral Viral load Viral RNA viral RNA detection virus isolate Virus neutralization [DOI] 10.1016/j.jcv.2021.105060 PMC 바로가기 [Article Type] Article
Crohn’s and Colitis Canada’s 2021 Impact of COVID-19 and Inflammatory Bowel Disease in Canada: Children and Expectant Mothers With Inflammatory Bowel DiseaseSupplement Articles Published on 2021-12-052022-10-29 Journal: Journal of the Canadian Association of Gastroenterology [Category] COVID-19, [키워드] acute respiratory syndrome affected Anxiety Care children coronavirus Coronavirus disease 2019 Coronavirus disease 2019 (COVID-19) Corticosteroids COVID-19 COVID-19 severity Crohn’s disease death Depression Disease activity effort Epidemiology examined global pandemic group hospital IBD Impact increased risk Inflammation Inflammatory bowel disease less manifestation Manifestations measure medication mental health mild infection Older pandemic pediatrics Pregnancy pregnant preterm delivery Protective provided reduce required resulting SARS-CoV-2 severe COVID-19 significantly ulcerative colitis vaccination [DOI] 10.1093/jcag/gwab030 PMC 바로가기 [Article Type] Supplement Articles
SARS-CoV-2 Seroprevalence in Germany독일의 SARS-CoV-2 혈청 유병률Article Published on 2021-12-032022-09-11 Journal: Deutsches Ärzteblatt international [Category] SARS, 치료기술, [키워드] antigenic association assumed Asymptomatic average blood sample Blood samples calculated Chemnitz Course declined determine evaluate Factors Fatality rate First wave Germany IFR include Infection infections information Magdeburg many case many cases mild infection pandemic participant PCR public health quarantine random recruited Region registration number reported SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections Seropositivity Seroprevalence Seven smoking Spread Study participants Surveillance Test tested These data was tested were used [DOI] 10.3238/arztebl.m2021.0364 PMC 바로가기 [Article Type] Article
Low risk of reinfections and relation with serological response after recovery from the first wave of COVID-19COVID-19의 첫 번째 물결에서 회복된 후 재감염 위험이 낮고 혈청학적 반응과의 관계Article Published on 2021-12-012022-09-12 Journal: European Journal of Clinical Microbiology & Infect [Category] MERS, SARS, 진단, [키워드] age antibody Asymptomatic collected COVID-19 COVID-19 reinfection female First wave Follow-up healthcare IgG IgM response immunization individuals with COVID-19 IQR Italy longitudinal longitudinal study manifested median median age Mild mild infection observation period occurred Outpatient Patient patients Reinfection risk SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 IgG SARS-CoV-2 IgM SARS-CoV-2 reinfection SARS-CoV-2 serology serological serological response serology seronegative seropositive the disease with COVID-19 [DOI] 10.1007/s10096-021-04335-x PMC 바로가기 [Article Type] Article