NCBI – Page 3 – Communicable Diseases Research

Targeting conserved N-glycosylation blocks SARS-CoV-2 variant infection in vitro

보존된 N-글리코실화를 표적으로 하는 것은 시험관 내에서 SARS-CoV-2 변이체 감염을 차단합니다

Article

Published on 2021-12-012022-09-11
Journal: EBioMedicine [Category] SARS, 변종, 진단,

Evolutionary and Antigenic Profiling of the Tendentious D614G Mutation of SARS-CoV-2 in Gujarat, India

Genetics

Published on 2021-11-112022-10-31
Journal: Frontiers in Genetics [Category] COVID-19,

Differential mutation profile of SARS-CoV-2 proteins across deceased and asymptomatic patients

사망 및 무증상 환자에 대한 SARS-CoV-2 단백질의 차등 돌연변이 프로파일

Article

Published on 2021-09-252022-09-11
Journal: Chemico-biological interactions [Category] SARS, 변종,

[키워드] accession number appear Asymptomatic asymptomatic patient carried clinical status correlation country Deceased decrease Deleterious followed by Genome Genome sequences GISAID highest incidence MAPP mutant Mutation mutations NC-045512.2 NCBI Neutral non-structural protein NSP2 Nsp3 ORF3a pathogenicity Patient PolyPhen-2 predict predicted present Prevalence prevalent Protein protein 3 protein stability reference sequence repertoire SARS-CoV-2 SARS-CoV-2 genome sequence SARS-CoV-2 genome sequences SARS-COV-2 infection SARS-CoV-2 protein SARS-CoV-2 proteins SARS-CoV-2 sequence several variant several variants SIFT SNAP spike Spike protein Spread stability variant variants was used
[DOI] 10.1016/j.cbi.2021.109598 PMC 바로가기 [Article Type] Article

Data on multiple SARS-CoV-2 surface glycoprotein alignments

Data Article

Published on 2021-09-232022-10-31
Journal: Sensors (Basel, Switzerland) [Category] COVID-19,

[키워드] acute respiratory syndrome Amino acid analysed Cobalt Complete computational analysis coronavirus country dataset Europe Genome Mutation mutations NC_045512 NCBI NCBI GenBank processed Protein SARS-CoV-2 Structure Studio Surface glycoprotein variants Visual were used Wuhan-Hu-1
[DOI] 10.1016/j.dib.2021.107414 PMC 바로가기 [Article Type] Data Article

Single-cell RNA sequencing of SARS-CoV-2 cell entry factors in the preconceptional human endometrium

선입견 인간 자궁 내막에서 SARS-CoV-2 세포 진입 인자의 단일 세포 RNA 시퀀싱

Article

Published on 2021-09-182022-09-11
Journal: Human reproduction (Oxford, England) [Category] SARS, 치료기술,

[키워드] ACE2 Analysis ANPEP Asymptomatic COVID-19 Biohub biopsy board BSG canonical carriers caution CD209 Cell cell entry cell type cells chance CLEC4G Cohort conducted COVID-19 CTSB CTSL dataset Donor during pregnancy early pregnancy Efficiency epithelial cell epithelial cells European examined expressed expression expression of gene Factor Focusing framework furin Gene Expression Gene Expression Omnibus head healthy Horizon IFITM1 implication Infection Innovation luminal LY6E menstrual menstrual cycle Miguel NCBI NRP1 offer Pregnancy processed Program proliferative Proteases protein expression raw data receptor receptor ACE2 reported reproductive resource reveal risk risk of infection RNA sequencing SARS-CoV-2 SARS-CoV-2 cell SARS-CoV-2 receptor scRNAseq Sequence Read Archive single-cell level Single-cell RNA-sequencing Spanish Stanford stromal cells supported the SARS-CoV-2 tissue TMPRSS11A TMPRSS2 TMPRSS4 transcriptomics transmission of SARS-CoV-2 Type union vertical transmission viral infection virus
[DOI] 10.1093/humrep/deab183 PMC 바로가기 [Article Type] Article

Dating the Common Ancestor from an NCBI Tree of 83688 High-Quality and Full-Length SARS-CoV-2 Genomes

83688 고품질 및 전장 SARS-COV-2 게놈의 NCBI 트리에서 공통 조상과 데이트

Article

Published on 2021-09-082022-09-10
Journal: Viruses [Category] SARS, 유전자 메커니즘,

Comparative study of predicted miRNA between Indonesia and China (Wuhan) SARS-CoV-2: a bioinformatics analysis

인도네시아와 중국(우한) SARS-CoV-2 간의 예측 miRNA 비교 연구: 생물정보학 분석

Article

Published on 2021-09-012022-09-11
Journal: Genes & genomics [Category] Coronavirus, SARS, 치료기술, 치료제,

[키워드] Analysis analyzed association binding bioinformatics Bioinformatics analysis both groups center Characteristics chi-square test China Comparative contribute COVID-19 case Data center detect DIANA-miRPath dysregulation enhancement FIVE Gene ontology Gene ontology analysis Genetic genetic regulation Genome data mining genomic Genomics GISAID host miRNA host miRNAs host mRNA https://www.gisaid.org/ immune system in both group indicate Indonesia Inflammation less majority mature miRNAs microRNA miRNA miRNA target miRNA targets miRNAs NCBI ORF1ab gene pandemic predict predicted Regulation Research SARS-CoV-2 SARS-CoV-2 mutation SARS-CoV-2 mutations SARS-CoV-2 sequence SARS-CoV-2 sequences significant difference statistical statistical analysis Variation variations Viral RNA was used Wuhan Wuhan, China
[DOI] 10.1007/s13258-021-01119-7 PMC 바로가기 [Article Type] Article

SARS-CoV-2: Origin, Intermediate Host and Allergenicity Features and Hypotheses

Article

Published on 2021-08-302022-10-31
Journal: International journal for equity in health [Category] COVID-19,

[키워드] affinities allergenicity Americans Antigen bat binding affinity calculated Chinese Combination coronavirus COVID-19 develop early immunization evaluate Evolution Factor forms Guangdong high temperature HLA HLA allele HLA class I Host Hypothesis immunization include indicate individual infection rate intermediary reservoir intermediate Intervention leukocyte MHC binding affinity Mus NCBI origin outbreak site Patient Phylogenetic analysis predicted promoted Prophylactic RaTG13 Rattus rodent SARS-CoV SARS-CoV-2 self-limitation Spike protein spontaneous mutation subclade Surveillance the binding affinity the spike protein Viral mutations virulent virus virus spike protein Wuhan
[DOI] 10.3390/healthcare9091132 PMC 바로가기 [Article Type] Article

Molecular docking and dynamic simulation of conserved B cell epitope of SARS-CoV-2 glycoprotein Indonesian isolates: an immunoinformatic approach

Research Article

Published on 2021-08-162022-10-31
Journal: F1000Research [Category] COVID-19, MERS, SARS,

[키워드] Activation acute respiratory syndrome addition Antigen antigenic approach B cell B cell epitope BCR binding Brazil calculated Candidates carried CD4+ cell China complex conserved conserved region. coronavirus country COVID-19 differentiation docking epitope gene sequence GISAID histocompatibility complex HLA Immunoinformatic India Indonesia Infectious disease investigated isolate isolates leukocyte lowest memory response MHC-II molecular NCBI non-toxic peptide predicted produced receptor Region SARS-CoV-2 SARS-CoV-2 glycoprotein SARS-CoV-2 isolate SARS-CoV-2 spike glycoprotein sequence South Africa spike glycoprotein T cell The United States the vaccine Toxicity United Kingdom Vaccine vaccine candidate Virus neutralization Wuhan
[DOI] 10.12688/f1000research.54258.1 PMC 바로가기 [Article Type] Research Article

The Production of Standardized Samples with Known Concentrations for Severe Acute Respiratory Syndrome Coronavirus 2 RT-qPCR Testing Validation for Developing Countries in the Period of the Pandemic Era

중증 급성 호흡기 증후군 코로나 바이러스 2 RT-QPCR 테스트 검증을위한 공지 된 농도를 갖는 표준화 된 샘플의 생산은 전염병 시대의 개발 도상국을위한 국가를위한 국가에 대한 검증

Research Article

Published on 2021-08-032022-09-10
Journal: BioMed Research International [Category] 진단, 치료기술,

[키워드] Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus Bioanalytical Method Validation biosafety level Biosafety Level 3 biosafety level 3 laboratory caused Concentration coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 country COVID-19 criterion database dependent on Developing diagnose diagnostic diagnostic testing evaluated Factors gold gold standard implementation inactivated Laboratory less level 3 limit limit of detection Linear regression linearity long term NCBI pandemic pandemic era Period Pneumonia Precision Production provide public health Quantitative R 2 reached respiratory Result reverse transcription PCR RT-qPCR Sample SARS-CoV-2 SARS-CoV-2 testing Sensitivity and specificity severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Spread synthesized RNA Testing the disease threat validation verification virus sample
[DOI] 10.1155/2021/5516344 PMC 바로가기 [Article Type] Research Article