Comparison of six antibody assays and two combination assays for COVID-19COVID-19에 대한 6 개의 항체 분석 및 2 개의 조합 분석의 비교Comparative Study Published on 2022-02-032022-09-01 Journal: Virology Journal [Category] COVID19(2023년), Fulltext, MERS, SARS, 진단, [키워드] antibody assay Antibody testing Combination concordance rate COVID-19 COVID-19 diagnosis COVID-19 group COVID-19 infection COVID-19 patient early stage Elecsy Elecsys epidemiological epidemiological surveillance evaluated Evidence evidence of except for Flash iFlash IgG IgM individual late stage negative control performed PerkinElmer Result SARS-CoV-2 SARS-COV-2 infection sensitive assay sensitivity serology seropositive serum sample serum samples specificity Surveillance symptom onset [DOI] 10.1186/s12985-022-01752-y PMC 바로가기 [Article Type] Comparative Study
A study of quality assessment in SARS-CoV-2 pathogen nucleic acid amplification tests performance; from the results of external quality assessment survey of clinical laboratories in the Tokyo Metropolitan Government external quality assessment program in 2020SARS-CoV-2 병원체 핵산 증폭 시험 성능의 품질 평가 연구; 2020년 도쿄도 외부 품질 평가 프로그램의 임상 실험실에 대한 외부 품질 평가 조사 결과Article Published on 2022-02-012022-09-11 Journal: Journal of infection and chemotherapy : official j [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] adopted amplification automated company conducted COVID-19 cycle Detection limit equipment External external quality control False negative False positive implementation Influenza Influenza virus Laboratory LAMP Loop-mediated isothermal amplification Loop-mediated isothermal amplification (LAMP) method NAAT name negative control non-specific nucleic acid nucleic acid amplification nucleic acid amplification testing nucleic acid extraction nucleic acid extraction kit participant pathogen positive control positive sample Quality control real-time RT-PCR reported RT-PCR SARS-CoV-2 target gene Tokyo virus genome [DOI] 10.1016/j.jiac.2021.10.027 PMC 바로가기 [Article Type] Article
Metabolomics study of COVID-19 patients in four different clinical stages4 가지 임상 단계에서 Covid-19 환자의 대사체 연구Article Published on 2022-01-312022-09-10 Journal: Scientific Reports [Category] 바이오마커, 진단, [키워드] (COronaVIrus Disease 2019) acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition Admission Analysis Asymptomatic disease bile acid bile acids biological pathway Biomarker Biomarkers change Clinical outcome Clinical stage coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 illness COVID-19 patient Deceased defined diagnose disease early stage fatty acids Final groups help hospital hospital discharge hospitalized patient hospitalized patients HPLC Human individual Infection information involved ketone ketone bodies mass spectrometry metabolism metabolite metabolomics Mild Mild disease negative control omeprazole outcome pandemic Patient patients plasma plasma sample plasma samples positive patient Potential biomarker potential biomarkers predict produced Prognosis purines respiratory SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus severe disease subsequent Tryptophan viral infection with mild disease [DOI] 10.1038/s41598-022-05667-0 PMC 바로가기 [Article Type] Article
Comparative risk of incidence and clinical outcomes of COVID-19 among proton pump inhibitor and histamine-2 receptor antagonist short-term users: a nationwide retrospective cohort studyResearch Published on 2022-01-172022-10-28 Journal: BMC Pharmacology & Toxicology [Category] COVID-19, [키워드] Acid suppressants all-cause mortality association calibrated Clinical outcome Comparative conducted confidence interval COVID-19 COVID-19 disease database Epidemiology estimate evaluate hazard ratio Hospitalization incidence inhibitor Intensive Intervention lower risk negative control outcome outcomes patients patients with COVID-19 pharmacovigilance PPI propensity score matching receptor Respiratory disease respiratory intervention Result retrospective cohort study Retrospective studies risk risk of COVID-19 secondary outcome significantly South Korea supplementary material tested used data were used [DOI] 10.1186/s40360-022-00549-7 PMC 바로가기 [Article Type] Research
Inferring the stabilization effects of SARS-CoV-2 variants on the binding with ACE2 receptorArticle Published on 2022-01-062022-10-04 Journal: Communications Biology [Category] SARS, 변종, [키워드] ACE2 receptor acute respiratory syndrome addition African amino acid substitution Analysis antigenicity binding characteristic complex complexes contagiousness coronavirus Effect English feature greater help human ACE2 receptor Interaction molecular Molecular conformation Molecular dynamics simulation Molecular modelling MONITOR Mutation negative control no effect observation occur pandemic performed phenotype phenotypic provoke residue SARS-CoV-2 spike protein SARS-CoV-2 spike variant SARS-CoV-2 variant selected selective several variant South specific mutation spike variant spike variants Spread stability stabilizing effect Surveillance the SARS-CoV-2 the spike protein variant variants Variation viral genome virus while wild type [DOI] 10.1038/s42003-021-02946-w PMC 바로가기 [Article Type] Article
Prognostic value of circulating calprotectin levels on the clinical course of COVID-19 differs between serum, heparin, EDTA and citrate sample typesResearch article Published on 2022-01-012022-10-05 Journal: Clinica chimica acta; international journal of cli [Category] SARS, 바이오마커, [키워드] Analysis AUC AUROC Biomarker calprotectin circulating Clinical course clinician COVID-19 COVID-19 patient COVID-19 patients CRP Deceased defined discriminatory power EDTA help highest ICU admission IL-6 LDH material negative control outcome outperform Patient plasma populations pre-analytics predict procalcitonin Prognostic value Result SARS-CoV-2 SARS-CoV-2 pandemic serum severity of COVID-19 significantly higher [DOI] 10.1016/j.cca.2021.12.011 [Article Type] Research article
GP consultation rates for sequelae after acute covid-19 in patients managed in the community or hospital in the UK: population based studyResearch Published on 2021-12-292022-10-28 Journal: The BMJ [Category] COVID-19, Fulltext, SARS, [키워드] 95% confidence interval abdominal pain adjusted hazard ratio Analysis Anxiety Asthma Aurum breathlessness Chest clinical Cognitive impairment cohorts Community contributing to Cox regression database Depression described determine Diagnosis diarrhoea disease Diseases dose England first vaccination Follow-up healthcare hospital individual Infection Influenza Ischaemic heart disease joint Loss of Smell Lung fibrosis median age nausea negative control neuropathic non-steroidal anti-inflammatory drug objective outcome outcome measure Pain pandemic Paracetamol participant Patient patients with influenza Population Practice proportions Rate reduced relative renal repeated Result setting significantly higher symptomatic Symptoms vaccination Venous Thromboembolism [DOI] 10.1136/bmj-2021-065834 PMC 바로가기 [Article Type] Research
Angiotensin II receptor I auto-antibodies following SARS-CoV-2 infectionResearch Article Published on 2021-11-172022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, [키워드] Activation adjusted age and sex Angiotensin II association auto-antibody autoantibody Coagulopathy Comorbidity controls Coronavirus disease 2019 COVID-19 COVID-19 case COVID-19 disease severity diabetes disease endothelial hypertension individual Logistic median Mild negative control not differ pathology Prevalence pro-thrombotic receptor Result SARS-COV-2 infection severe COVID-19 severe disease significantly higher Support type I Vascular [DOI] 10.1371/journal.pone.0259902 PMC 바로가기 [Article Type] Research Article
Association of SARS-CoV-2 Infection With Psychological Distress, Psychotropic Prescribing, Fatigue, and Sleep Problems Among UK Primary Care PatientsResearch Published on 2021-11-162022-10-29 Journal: JAMA Network Open [Category] COVID-19, MERS, SARS, [키워드] 95% CI acute phase addition adjusted adjusted hazard ratio age Analysis analyzed Anxiety association Aurum body mass index Care change clinical Cohort cohort study Comorbidities confounders Control COVID-19 criteria Depression eligible English Evidence exposure fatigue finding Follow-up Health Importance Inconclusive increased risk individual Infection Influenza less measure median mental illness Model morbidity negative control objective Older pandemic participant patients patients with SARS-CoV-2 Point polymerase chain positive positive result Practice prescribing primary care problem problems Psychiatric Psychotropic Registered Relevance responsible Result risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 test setting Sex Sleep smoking subgroups subsequent were excluded women [DOI] 10.1001/jamanetworkopen.2021.34803 PMC 바로가기 [Article Type] Research
High anti-SARS-CoV-2 antibody seroconversion rates before the second wave in Manaus, Brazil, and the protective effect of social behaviour measures: results from the prospective DETECTCoV-19 cohort브라질 마나우스의 2차 유행 이전 높은 항 SARS-CoV-2 항체 혈청 전환율 및 사회적 행동 조치의 보호 효과: 전향적 DETECTCoV-19 코호트의 결과Article Published on 2021-11-012022-09-11 Journal: The Lancet. Global health [Category] MERS, SARS, 진단, 치료법, [키워드] 95% CI adjusted analyses Analysis anti-SARS-CoV-2 anti-SARS-CoV-2 antibody association Asymptomatic baseline Brazil calculated city Cohort Comorbidities Compliance Contact contact with COVID-19 COVID-19 case COVID-19 diagnosis COVID-19 pandemic criteria defined disease status education event first visit flu-like symptom flu-like symptoms Follow-up follow-up period had no Health Health Organization health system house household IgG antibody implementation in-house ELISA incidence incidence rate Increased increased the risk Infection transmission information Intervention IQR Mask measure Measures median negative control nucleocapsid optical optical density organization Pan participant physical distancing Poisson regression model positive proportion Protective Protective behaviours protective effect rate ratios reactivity recruited Relaxation reported returned risk factor Risk factors second wave separated Seroconversion seroconversion rate seronegative seropositive serum Sociodemographic characteristics study cohort study period symptomatic Symptoms the epidemic Transmission variable was measured website were excluded with COVID-19 [DOI] 10.1016/S2214-109X(21)00355-7 PMC 바로가기 [Article Type] Article