Acute Disseminated Encephalomyelitis: A rare form of COVID-19’s neurotropismCase Report Published on 2021-10-112022-10-28 Journal: Annals of Medicine and Surgery [Category] COVID-19, [키워드] ADEM antigenic Brain country COVID-19 COVID-19 infection COVID-19 pandemic COVID-19 virus demyelinating demyelinating disorder disease disorder Encephalomyelitis etiology Immune-mediated immunosuppressive Inflammation mechanism Neurological involvement neurological manifestation neurotropism outcome Pathogenesis Patient radiological feature reported responsible Symptoms therapy vaccination Vaccine variety virus widespread women [DOI] 10.1016/j.amsu.2021.102940 PMC 바로가기 [Article Type] Case Report
The Possible Role of Microbial Proteases in Facilitating SARS-CoV-2 Brain InvasionOpinion Published on 2021-09-272022-10-28 Journal: Biology [Category] COVID-19, [키워드] ACE2 activate Angiotensin-converting enzyme Brain Cell cells Co-infection Cryptococcus Endothelial cell expression facilitate Facilitating fungal glycoprotein information instance Intervention Invasion Measures mechanism membrane fusion microbe microbial neurotropism organ Pathogens protease role S2 domain SARS-CoV-2 secretion shown simple understanding viral spike virus [DOI] 10.3390/biology10100966 PMC 바로가기 [Article Type] Opinion
Cranial nerve involvement in COVID-19COVID-19에서 뇌신경 침범Article Published on 2021-09-012022-09-11 Journal: American journal of otolaryngology [Category] 치료기술, [키워드] addition affected age analyzed approved caused Chain Reaction China COVID-19 COVID-19 disease cranial Cranial nerve cranial nerves died Effect evaluated examination function hospital Hospitalization lack material MERS neuroinvasion neurotropism outbreak pandemic Patient patients PCR polymerase chain polymerase chain reaction positive COVID-19 repeated resulting SARS-CoV2 Seven Spread statistically Symptoms the disease Treatment Turkey virus were excluded while Wuhan [DOI] 10.1016/j.amjoto.2021.102999 PMC 바로가기 [Article Type] Article
Glycoproteins of Predicted Amphibian and Reptile Lyssaviruses Can Mediate Infection of Mammalian and Reptile CellsCommunication Published on 2021-08-302023-05-31 Journal: Viruses [Category] Fulltext, 조류인플루엔자, [키워드] anole lyssavirus emerging disease frog lyssavirus host range neurotropism Rabies virus Vaccine zoonosis [DOI] 10.3390/v13091726 PMC 바로가기 [Article Type] Communication
The Hippocampal Vulnerability to Herpes Simplex Virus Type I Infection: Relevance to Alzheimer’s Disease and Memory ImpairmentReview Published on 2021-08-132024-09-02 Journal: Frontiers in Cellular Neuroscience [Category] 대상포진, [키워드] Alzheimer’s disease herpes simplex virus hippocampus infectious etiology memory impairment neurotropism [DOI] 10.3389/fncel.2021.695738 PMC 바로가기 [Article Type] Review
SARS-CoV-2 and the Brain: What Do We Know about the Causality of ‘Cognitive COVID?Review Published on 2021-08-022022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] approach Brain Causality caused changes in cognitive Cognitive impairment consequence coronavirus disease correlations COVID-19 COVID-19 case Deleterious delirium Diagnosis domains encephalopathy-like symptoms event Evidence exhibiting Healthcare system hematogenous highlight identify Immune cell Infection Inflammation intubation management mechanism mechanisms memory MERS-CoV mitigate mRNA neuronal neurotropism olfactory outbreak pandemic pathway Patient Prevalence prevention pro-inflammatory state proportion psychosocial stressor Quality of life raised rehabilitation risk SARS-CoV SARS-CoV-2 SARS-COV-2 infection spike glycoprotein Spread Symptom Symptoms syndrome Transmission unique Vaccine vectors virus [DOI] 10.3390/jcm10153441 PMC 바로가기 [Article Type] Review
SARS-CoV-2 may trigger inflammasome and pyroptosis in the central nervous system: a mechanistic view of neurotropismReview Published on 2021-07-092023-06-16 Journal: Inflammopharmacology [Category] MERS, SARS, [키워드] Inflammasome neurotropism pro-inflammatory cytokines pyroptosis SARS-CoV-2 [DOI] 10.1007/s10787-021-00845-4 PMC 바로가기 [Article Type] Review
Replication Kinetics, Cell Tropism, and Associated Immune Responses in SARS-CoV-2- and H5N1 Virus-Infected Human Induced Pluripotent Stem Cell-Derived Neural ModelsResearch Article Published on 2021-06-232022-10-30 Journal: mSphere [Category] COVID-19, MERS, SARS, [키워드] accumulating ACE2 acute respiratory syndrome angiotensin-converting enzyme 2 associated immune response Brain cell tropism cell type cells Central nervous system cerebrospinal fluid CNS contribute coronavirus COVID-19 COVID-19 patients Culture cultures disease Evidence expression H5N1 H5N1 influenza A H5N1 virus highly pathogenic hiPSC neurons Human Hypothesis IL-8 induced infect Infection influenza A virus Influenza virus interferon Invasion investigated Kinetics local immune response Model Neural Neurological complication Neurological complications Neuron neurons neurotropic neurotropism NPR1 olfactory Pathogenesis pluripotent stem cell protease replicated replication kinetics response SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 replication serine 2 Spread STEM subsequent Support TMPRSS2 transmembrane triggered triggering tropism type III interferon variety virus virus replication virus spread [DOI] 10.1128/mSphere.00270-21 PMC 바로가기 [Article Type] Research Article
Susceptibility of neuroblastoma and glioblastoma cell lines to SARS-CoV-2 infectionSARS-CoV-2 감염에 대한 신경모세포종 및 교모세포종 세포주의 감수성Article Published on 2021-05-012022-09-11 Journal: Brain research [Category] SARS, 치료기술, [키워드] Analysis Apoptosis Cell cell line cell lines cell type cells Coronavirus-2 CTSB CTSL Cytopathic effect death demonstrated described downregulation epithelial cell epithelial cells Express Gene Expression Genes Glioblastoma Glutamate idea In situ hybridization infected cell infected cells Infection maintain MOI MOIs Neuroblastoma neuronal neurotropism Perspective quantification replicate retinoic acid RNA SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 strain severe acute respiratory coronavirus Severe acute respiratory coronavirus-2 SH-SY5Y susceptibility tropism upregulation Vero E6 VERO E6 cells virus were expressed were infected [DOI] 10.1016/j.brainres.2021.147344 PMC 바로가기 [Article Type] Article
Neurological Consequences of SARS-CoV-2 Infection and Concurrence of Treatment-Induced Neuropsychiatric Adverse Events in COVID-19 Patients: Navigating the UnchartedMolecular Biosciences Published on 2021-02-182022-10-31 Journal: Frontiers in Molecular Biosciences [Category] COVID-19, [키워드] ACE2 acute respiratory syndrome Adverse adverse event Affect angiotensin-converting enzyme 2 anti-retroviral drug Antibiotics bind Central nervous system Chloroquine clinically CNS Combination Complication concurrence consequence contributing to coronavirus Corticosteroid COVID - 19 COVID-19 Critical Dexamethasone Diseases dissemination Drug interactions drug-drug interaction Encephalitis Encephalopathy event Evidence Favipiravir Guillain-barrè syndrome help hematogenous Hemorrhagic highlight human cell Hydroxychloroquine Hypogeusia Hyposmia immune responses include induce Injury leukoencephalopathy Lopinavir-ritonavir mechanism mechanisms medication Meningitis morbidity and mortality nervous system neurologic neurologic manifestations Neurological disorder neurological manifestation neuronal Neuropsychiatric neuropsychiatric adverse effects neurotropic neurotropism off-label outcome pandemic pathophysiological Pathways Perspective Pneumonia Post-infection potential therapy Psychiatric disorders psychological Impact receptor Remdesivir Repurposed drug researchers Respiratory complications SARS – CoV – 2 SARS-CoV-2 SARS-COV-2 infection stroke syndrome therapeutic potential thrombosis Tocilizumab Uncharted venous virus virus infection with COVID-19 [DOI] 10.3389/fmolb.2021.627723 PMC 바로가기 [Article Type] Molecular Biosciences