Oral hymecromone decreases hyaluronan in human study participants
경구 hymecromone은 인간 연구 참가자의 hyaluronan을 감소시킵니다
Clinical Trial
[키워드] 4-methylumbelliferone
Accelerator
Administered
Adults
analyzed
animal models
approved
approved drugs
Arm
asked
baseline
breath
catalyst
Concentration
conducted
COVID-19 infection
decrease
dose
dose-dependent manner
doses
drug concentration
Europe
exposure to
Extracellular matrix
fibrosis
glycosaminoglycan
greater
greater decrease
healthy
hymecromone
hypertension
implicated
in vitro
Inflammation
inhibit
inhibitor
Medicine
metabolite
NIH
Open-label
oral
other diseases
Pathogenesis
pathophysiology
pulmonary disease
pulmonary diseases
pulmonary fibrosis
pulmonary hypertension
reduction in
serum
significant decrease
single-center
sputum
Stanford
study participant
subject
therapy
Tolerability
Treatment
[DOI] 10.1172/JCI157983 PMC 바로가기 [Article Type] Clinical Trial
[DOI] 10.1172/JCI157983 PMC 바로가기 [Article Type] Clinical Trial