Continent-Wide Analysis of COVID 19: Total Cases, Deaths, Tests, Socio-Economic, and Morbidity Factors Associated to the Mortality Rate, and Forecasting Analysis in 2020–2021Article Published on 2021-05-182022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] acute respiratory syndrome age Analysis ARIMA Asia average China clinical feature Continents coronavirus Correlation analysis COVID COVID-19 COVID-19 case death deaths defined diabetes Epidemiology Europe Factor Forecasting GDP highest hospital Infection less Linear regression lowest Mortality mortality rate North America Oceania pandemic predict predicted Rate regression analysis reported risk factor Risk factors SARS-CoV-2 South America statistical Total was performed was recorded were used [DOI] 10.3390/ijerph18105350 PMC 바로가기 [Article Type] Article
Global Discrepancies between Numbers of Available SARS-CoV-2 Genomes and Human Development Indexes at Country Scales국가 규모에서 사용 가능한 SARS-CoV-2 게놈 수와 인간 개발 지수 간의 글로벌 불일치Brief Report Published on 2021-04-282022-09-10 Journal: Viruses [Category] MERS, SARS, 변종, [키워드] African analyzed Asia Asian capita China comparison Comparisons country country-scale development death deaths development discrepancy downloaded eight Europe European country File GDP Genome genome sequence genomes genomes sequenced GISAID database highlight Human Human Development Human Development Index Life expectancy Microsoft Excel Next-generation sequencing number Oceania Population size RANK ranking released SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genome sequence SARS-CoV-2 genome sequences SARS-CoV-2 genomes scale Spread variant website world [DOI] 10.3390/v13050775 PMC 바로가기 [Article Type] Brief Report
Convalescent plasma therapy in COVID-19 critically ill patients during advanced phases of clinical trials and their preliminary resultsReview Published on 2021-04-092022-10-31 Journal: Einstein [Category] COVID-19, MERS, SARS, [키워드] adverse events applied approach article base Betacoronavírus Betacoronavirus clinical trial combater conditions convalescent plasma Convalescent plasma therapy Coronavirus infections COVID-19 COVID-19 patients Critical case Critically ill patient database decrease disease drugs Efficacy effort eficácia Europe evaluate Evidence highlight Hospitalized hospitalized patients immunization Immunization, passive Imunização Imunização passiva Infecções por coronavírus Intervention less life-threatening Mortality MOST multicenter nCOV-2019 North America Oceania outcome pacientes com COVID-19 Pacientes hospitalizados Patient patients with COVID-19 performed Placebo plasma Plasma convalescente plasma exchange protocol reported SARS-CoV-2 severe disease Standard therapy the SARS-CoV-2 therapy [DOI] 10.31744/einstein_journal/2021RW6186 PMC 바로가기 [Article Type] Review
Most Japanese individuals are genetically predisposed to recognize an immunogenic protein fragment shared between COVID-19 and common cold coronavirusesBrief Report Published on 2021-03-102022-10-31 Journal: F1000Research [Category] COVID-19, MERS, SARS, [키워드] addressed Affect allele Americas Asia CD8 Combination common cold common cold coronavirus coronavirus COVID-19 COVID-19 patient epitope HLA HLA-A*24:02 immune memory immunogenic individual infections Japanese majority MHC MHC class I MOST Oceania peptide Population Protein recognize Specificities SPRWYFYYL T cell VYIGDPAQL [DOI] 10.12688/f1000research.51479.1 PMC 바로가기 [Article Type] Brief Report
Spatiotemporal visualization for the global COVID-19 surveillance by balloon chartResearch Article Published on 2021-03-012022-10-29 Journal: Infectious Diseases of Poverty [Category] COVID-19, [키워드] alteration Asia Balloon chart Belgium Brazil browser Bulgaria CFR changes in coronavirus disease country COVID-19 COVID-19 case COVID-19 pandemic death dimension East Epidemics epidemiological Europe European exceptional Fatality rate France Global highest Hungary Iran Italy Johns Hopkins University less methodology morbidity Mortality North North America Oceania offered pandemic programming progression public health Region regions reported Result rising Seven severity South South Africa South America Spain spatiotemporal Spatiotemporal visualization Spread Surveillance Transmissibility USA West widespread [DOI] 10.1186/s40249-021-00800-z PMC 바로가기 [Article Type] Research Article
Evolutionary Dynamics and Dissemination Pattern of the SARS-CoV-2 Lineage B.1.1.33 During the Early Pandemic Phase in BrazilMicrobiology Published on 2021-02-172022-10-31 Journal: Frontiers in Microbiology [Category] COVID-19, [키워드] acute respiratory syndrome Analysis B.1.1 B.1.1.33 Brazil clade collected Community community transmission Continuous coronavirus Coronavirus disease 2019 Coronavirus-2 country Dynamics effective Effectiveness Epidemic Europe fraction genetic lineages Genome genomic implementation indicate information introduced investigated Lineage Local median moderate mutations North America Oceania pattern phase phylodynamic Prevalence Public health intervention reached reduced Region reproductive responsible reveal Rio de Janeiro SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 lineage severe acute respiratory syndrome coronavirus-2 South strain Surveillance the SARS-CoV-2 Travel viral genome Viral transmission [DOI] 10.3389/fmicb.2020.615280 PMC 바로가기 [Article Type] Microbiology
Global Geographic and Temporal Analysis of SARS-CoV-2 Haplotypes Normalized by COVID-19 Cases During the PandemicMicrobiology Published on 2021-02-172022-10-31 Journal: Frontiers in Microbiology [Category] COVID-19, [키워드] age analyzed approach Asia available data characterized circulating country COVID-19 COVID-19 case distribution Epidemiology Europe Evolution FIVE functional Gender Genome genomes Geographic global analysis Haplotype haplotypes help hypothese identify Isolation major haplotype major haplotypes Mutation mutations nine North America NSP2 Oceania operational taxonomic units pathogenicity Patient phylogenomic Region relative frequency reported SARS-CoV-2 sequenced sequenced genome South America T85I Temporal Transmissibility unique viral pandemic virus [DOI] 10.3389/fmicb.2021.612432 PMC 바로가기 [Article Type] Microbiology
Molecular Epidemiology Surveillance of SARS-CoV-2: Mutations and Genetic Diversity One Year after EmergingArticle Published on 2021-02-092022-10-28 Journal: Pathogens [Category] COVID-19, [키워드] acute respiratory syndrome analyzed association changes in Complete Continuous coronavirus D614G detect disease severity Diversity downloaded Europe Frequency GenBank genetic diversity Genome geographical region GISAID hotspot implicated IMPROVE increase in information molecular molecular surveillance MONITOR Mutation mutations natural selection Non-synonymous non-synonymous substitution Nsp12 NSP2 Oceania P323L pandemic Protein Region reported SARS-CoV-2 Seven spike Spread Substitution substitutions Surveillance the Spike Transmission dynamics variant virus Wuhan, China Year [DOI] 10.3390/pathogens10020184 PMC 바로가기 [Article Type] Article
Key genetic elements, single and in clusters, underlying geographically dependent SARS-CoV-2 genetic adaptation and their impact on binding affinity for drugs and immune control지리적으로 의존적인 SARS-CoV-2 유전자 적응의 기초가 되는 단일 및 클러스터의 주요 유전 요소 및 약물 및 면역 조절에 대한 결합 친화도에 미치는 영향Article Published on 2021-01-192022-09-11 Journal: Journal of Antimicrobial Chemotherapy [Category] 변종, 치료제, [키워드] (RdRp acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 America amino acids analogues analysed antigenicity Asia B cell best binding affinity chymotrypsin Chymotrypsin-like protease circulation class close monitoring Cluster Clustering Clusters Compound Coronavirus-2 country drug drug susceptibility drugs Effectiveness element elements epitope Epitopes Europe evaluate FDA-approved drug FDA-approved drugs Genetic Hierarchical hierarchical clustering highlighting immune inhibitor modulate modulating Mutation Neutralizing antibodies neutralizing antibody occurred Oceania Penciclovir predicted protease purine purine analogue RdRP RdRp inhibitor Recognition reduced Remdesivir RNA-dependent RNA polymerase SARS-CoV-2 SARS-CoV-2 proteins SARS-CoV-2 sequence SARS-CoV-2 sequences severe acute respiratory syndrome Coronavirus specific mutation specific mutations stability tenofovir the binding affinity Treatment Vaccine Viral Viral proteins Virtual screening was used were assessed [DOI] 10.1093/jac/dkaa444 PMC 바로가기 [Article Type] Article
RCSB Protein Data Bank: powerful new tools for exploring 3D structures of biological macromolecules for basic and applied research and education in fundamental biology, biomedicine, biotechnology, bioengineering and energy sciencesAcademicSubjects/SCI00010 Published on 2021-01-082022-10-31 Journal: Nucleic Acids Research [Category] COVID-19, MERS, [키워드] 3D structure America applied Complete COVID-19 described example feature global pandemic host cell include macromolecular macromolecule Magnetic resonance spectroscopy Microscopy New nuclear Oceania operator PDB Protein Protein Data Bank released Research researchers resource resources SARS-CoV-2 protein Structure [DOI] 10.1093/nar/gkaa1038 PMC 바로가기 [Article Type] AcademicSubjects/SCI00010