Early DMO: a predictor of poor outcomes following cataract surgery in diabetic patients. The DICAT-II study Research Published on 2021-08-032022-10-05 Journal: Eye (London, England) [Category] 바이오마커, [키워드] after cataract both groups clinics CST diabete Diabetic diabetic patients Evidence eye eyes group in both groups Italian media multicentre oedema Optical coherence tomography outcome Patient patients peaked postoperative Result risk significantly visual acuity was performed were assessed worsening [DOI] 10.1038/s41433-021-01718-4 [Article Type] Research
ENDOCRINOLOGY IN THE TIME OF COVID-19-2021 UPDATES: The management of diabetes insipidus and hyponatraemiaClinical Practice Guidance Published on 2021-07-222022-10-31 Journal: European Journal of Endocrinology [Category] COVID-19, MERS, SARS, [키워드] Acute kidney injury Administered changed contribute COVID-19 COVID-19 patients develop diabete disease severity diuretics dose example high risk hospital hypovolaemia ICU insensible management Mortality multifactorial occur oedema Patient patients with diabete Pituitary plasma postoperative Prevalence Pyrexia recognize retained risk Severe case SIAD sodium specialist Symptoms Treatment Volume with COVID-19 [DOI] 10.1530/EJE-21-0596 PMC 바로가기 [Article Type] Clinical Practice Guidance
Multimodality cardiac evaluation in children and young adults with multisystem inflammation associated with COVID-19COVID-19와 관련된 다기관 염증이 있는 어린이 및 젊은 성인의 다양식 심장 평가Article Published on 2021-07-202022-09-11 Journal: European heart journal. Cardiovascular Imaging [Category] SARS, 치료기술, [키워드] Admission affecting age Anatomy cardiac function children close monitoring Computed tomography consecutive patient Coronary artery COVID-19 COVID-19 epidemic demonstrated dimension discharge Doppler dysfunction echocardiographic Effect Ejection fraction Hyper-inflammatory syndrome Inflammation inflammatory condition Kawasaki left magnetic resonance imaging median MIS-C multimodality Myocardial Myocardial infarction oedema Pancarditis Patient patients performed PIMS PIMS-TS presenting risk SARS-CoV-2 significantly the mean thrombotic tissue Valvular regurgitation with COVID-19 Z score [DOI] 10.1093/ehjci/jeaa212 PMC 바로가기 [Article Type] Article
Adventitial Microcirculation Is a Major Target of SARS-CoV-2-Mediated Vascular InflammationCase Report Published on 2021-07-202022-10-28 Journal: Biomolecules [Category] COVID-19, SARS, [키워드] ACE2 receptor affected alteration analyses Analysis artery disease cardiovascular complication Case report changes controls coronavirus Coronavirus disease-19 Course COVID-19 cytoplasm disease Endothelial cell endothelial injury expressed functional histological IHC IL-6 immunohistochemistry infected with SARS-CoV-2 Infection Inflammation Inflammatory lower limb Major mechanism media Microcirculation miRNA mRNA occlusive oedema popliteal Protein SARS-CoV-2 significantly increased staining target TEM transmission electron microscopy Vascular damage was reduced [DOI] 10.3390/biom11071063 PMC 바로가기 [Article Type] Case Report
Proning related bilateral anterior ischaemic optic neuropathy in a patient with COVID-19 related acute respiratory distress syndromeCase Report Published on 2021-07-132022-10-28 Journal: BMC ophthalmology [Category] COVID-19, SARS, [키워드] acute respiratory distress ARDS Compression ischaemic optic neuropathy counting finger COVID-19 COVID-19 pandemic Critical care Diagnosis eight Factor hypoxemic indirect ophthalmoscopy intensive care knowledge male mechanical ventilation Mild oedema pallor Patient patient with COVID-19 patients with COVID-19 peripheral vision Pneumonitis positive preserved prone prone positioning proning PROTECT reduced reported risk SARS-CoV- 2 Sedation syndrome the SARS-CoV-2 virus therapeutic strategy treat Treatment Vision loss visual acuity visual impairment [DOI] 10.1186/s12886-021-02028-9 PMC 바로가기 [Article Type] Case Report
Outcomes of COVID-19-positive acute coronary syndrome patients: A multisource electronic healthcare records study from EnglandObservational Study Published on 2021-07-012022-10-05 Journal: Journal of internal medicine [Category] SARS, 임상, [키워드] 30-Day mortality 95% confidence interval Acute coronary syndrome Acute myocardial infarction adjusted odds ratio antiplatelet Asian baseline black cardiac troponin cardiovascular disease Clinical characteristics conducted consecutive patient coronary syndrome coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 infection Diagnosis electronic healthcare record elevated England hospital Hospitalized In-hospital increased risk Infection invasive less medication morbidity and mortality Mortality NHS Non-COVID-19 Observational cohort study oedema Older outcome pandemic Patient patients hospitalized patients with COVID-19 Percutaneous coronary intervention presenting Primary outcome receive Shock study period Treatment ventricular [DOI] 10.1111/joim.13246 PMC 바로가기 [Article Type] Observational Study
Delayed follow-up of medical retina patients due to COVID-19: impact on disease activity and visual acuityCOVID-19로 인한 의료 망막 환자의 지연된 추적: 질병 활동 및 시력에 미치는 영향Article Published on 2021-07-012022-09-12 Journal: Graefe's Archive for Clinical and Experimental Oph [Category] SARS, 진단, [키워드] age Age-related macular degeneration analysed Anti-VEGF appear baseline Cohort collected college control group coronavirus COVID-19 Data analysis Delayed Diabetic Disease activity eye eyes feature Features Follow-up Guidance highest hospital injection intravitreal injection less loss of vision Macular oedema Ophthalmologist Optical coherence tomography outcome pandemic Patient patients patients receiving treatment random receiving reduce Retina retinal vein retrospective returned risk Sex significantly more statistically significant difference the patient Treatment Visual visual acuity was performed was recorded [DOI] 10.1007/s00417-021-05174-4 PMC 바로가기 [Article Type] Article
Is carbonic anhydrase inhibition useful as a complementary therapy of Covid-19 infection?탄산수소효소 억제가 Covid-19 감염의 보완 요법으로 유용합니까?Brief Report Published on 2021-06-022022-09-10 Journal: Journal of Enzyme Inhibition and Medicinal Chemist [Category] SARS, 신약개발, 치료제, [키워드] acetazolamide affected affecting Blood carbonic anhydrase caused clinically CO2 complementary contagious contagious disease cough country COVID-19 COVID-19 outbreak COVID-19 patients disease dysregulated Factor Fever globe Healthcare system high-altitude pulmonary oedema hypothesise hypoxaemia hypoxia inhibitor oedema outbreak Patient patients pharmacological treatment problem pulmonary disease pulmonary oedema Shortness of breath similarity specific inhibitor Symptom therapy treat [DOI] 10.1080/14756366.2021.1924165 PMC 바로가기 [Article Type] Brief Report
Increased extravascular lung water index (EVLWI) reflects rapid non-cardiogenic oedema and mortality in COVID-19 associated ARDSObservational Study Published on 2021-06-012022-10-04 Journal: Scientific Reports [Category] MERS, SARS, 임상, 치료법, [키워드] acute respiratory distress ARDS cardiac function cohorts comparable control group correlation COVID-19 COVID-19 associated ARDS COVID-19 negative COVID-19 patient develop Disease progression elevated evaluate Horowitz ICU in-hospital mortality Increased intubation lung marker MONITOR Mortality non-COVID-19 ARDS patients oedema parameter Patient patients with ARDS patients with COVID-19 progression prolonged intensive care reflect Respiratory distress syndrome significantly higher subsequent suggested syndrome Thermodilution Treatment vascular permeability ventilated patient viral infection viral persistence [DOI] 10.1038/s41598-021-91043-3 PMC 바로가기 [Article Type] Observational Study
Drugs that inhibit TMEM16 proteins block SARS-CoV-2 spike-induced syncytiaTMEM16 단백질을 억제하는 약물은 SARS-CoV-2 스파이크 유도 융합체를 차단합니다Article Published on 2021-06-012022-09-11 Journal: Nature [Category] MERS, SARS, 신약개발, 유전자 메커니즘, 진단, 치료기술, 치료제, [키워드] Activation alveolar approved drug calcium Cell Cell fusion cell surface Characteristics COVID-19 COVID-19 disease defined Deterioration diarrhoea disease drug effective effective drug effective drugs include Inflammatory response inhibit inhibited inhibitor inhibitors ion channel lung Lung function Lungs membrane membrane conductance morphology niclosamide oedema Pathogenesis patients with COVID-19 performed pharmacological Phosphatidylserine plasma membrane pneumocyte potential mechanism Protein repurposing responsible SARS-CoV-2 SARS-CoV-2 spike protein Screening screenings Spike protein Support Syncytia the cell the SARS-CoV-2 therapy thrombosis unique virus replication [DOI] 10.1038/s41586-021-03491-6 PMC 바로가기 [Article Type] Article