Infectious disease mRNA vaccines and a review on epitope prediction for vaccine designArticle Published on 2021-06-042023-07-01 Journal: Briefings in functional genomics [Category] SARS, [키워드] COVID-19 Epitope prediction machine learning mRNA vaccines other infectious diseases [DOI] 10.1093/bfgp/elab027 PMC 바로가기
SARS-CoV-2 proteins and anti-COVID-19 drugs induce lytic reactivation of an oncogenic virusSARS-CoV-2 단백질 및 항-COVID-19 약물은 발암성 바이러스의 용해성 재활성화를 유도합니다Article Published on 2021-06-032022-09-10 Journal: Communications Biology [Category] MERS, SARS, 치료기술, 치료법, 치료제, [키워드] antiviral drug antiviral drugs Cancer cancers causative agent caused Comorbidity coronavirus coronavirus disease coronavirus disease-2019 COVID-19 develop disease Diseases drug Efficacy encoded protein encoded proteins endemic area exposure to fatal disease host cell host cells Impact increased risk induce Infection Infectious diseases intracellular signaling manipulation mechanism Novel coronavirus novel coronavirus SARS-CoV-2 oncogenic other infectious diseases outbreak outcome Pathogenesis Pathways Patient patients required respiratory Respiratory disease risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 protein Symptoms Treatment Virology virus viruses [DOI] 10.1038/s42003-021-02220-z PMC 바로가기 [Article Type] Article
Impact of COVID-19 outbreaks and interventions on influenza in China and the United States중국과 미국의 인플루엔자에 대한 COVID-19 발생 및 개입의 영향Article Published on 2021-05-312022-09-10 Journal: Nature Communications [Category] SARS, 치료기술, [키워드] affected China coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 outbreak COVID-19 transmission decrease decreases Diseases Epidemic Epidemiology Evidence Impact Infection Infectious diseases Influenza Influenza virus Intervention mitigate NPI NPIs other infectious diseases pandemic Preventive medicine reduced remained respiratory respiratory diseases SARS-CoV-2 Seasonal influenza Spread the timing the United State Transmission dynamics United States viral epidemiology virus infection [DOI] 10.1038/s41467-021-23440-1 PMC 바로가기 [Article Type] Article
Metabolic biomarker profiling for identification of susceptibility to severe pneumonia and COVID-19 in the general population일반 인구에서 중증 폐렴 및 COVID-19에 대한 감수성을 식별하기 위한 대사 바이오마커 프로파일링Research Article Published on 2021-05-042022-09-10 Journal: eLife [Category] 바이오마커, [키워드] Alter amino acids association best Biomarker Biomarkers Blood blood sample Blood samples blood sampling cardiometabolic disease cardiometabolic diseases change chronic inflammation circulating collected complement condition Course COVID-19 COVID-19 pandemic determine develop diabete diabetes diagnosed died disease onset Diseases elevated eLife event fatty acids General population health condition healthy individual help high risk higher risk highest hospitalised Human Hypothesis identify Immunity impair include individual Infection infections Infectious disease Infectious diseases inhibited investigated life-threatening lipids liver liver diseases low-grade inflammation lowest measure metabolic molecular molecules NMR nuclear nuclear magnetic resonance Odds ratio Older age other infectious diseases performed Pneumonia Predictive Predictive value Proteins provided risk Risk factors severe COVID-19 severe pneumonia susceptibility the disease UK biobank United Kingdom [DOI] 10.7554/eLife.63033 PMC 바로가기 [Article Type] Research Article
One or two injections of MVA-vectored vaccine shields hACE2 transgenic mice from SARS-CoV-2 upper and lower respiratory tract infectionMVA 벡터 백신을 1~2회 주사하면 SARS-CoV-2 상부 및 하부 호흡기 감염으로부터 hACE2 형질전환 마우스를 보호할 수 있습니다423 Published on 2021-03-232022-09-10 Journal: Proceedings of the National Academy of Sciences of [Category] SARS, 유전자 메커니즘, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 anti-RBD antibodies antibody Cancer Cell chemokine clinical study Combination coronavirus coronavirus vaccine COVID-19 cytokine Deletion detection Diseases eight Express expressing form full-length S furin hACE2 hACE2 receptor human clinical trials IFNγ immune response immune responses Immunity immunized immunogenic in vitro indicated infected cells Infection infection with SARS-CoV-2 Infectious disease Infectious diseases inhibited injection Intramuscular injection intranasal lethal infection Lower respiratory tract lung Lungs mice modifications modified vaccinia virus modified vaccinia virus Ankara morbidity mRNAs Mutation nasal turbinate nasal turbinates neutralized neutralizing antibody nucleic acids occurred other infectious diseases pandemic passive transfer peptide Prevent prevented proline proline substitutions Protein Proteins provided pseudovirus purified RBD question RBD Receptor binding domain recombinant reduced Replication required respiratory S protein Safe SARS-CoV-2 SARS-CoV-2 replication SARS-CoV-2 S protein severe acute respiratory syndrome Coronavirus severe disease shown signal peptide Significance single vaccination smallpox vaccine Spread stimulate subgenomic mRNA subgenomic mRNAs subgenomic viral mRNA subgenomic viral mRNAs T cells the S protein the SARS-CoV-2 the signal peptide transfer transgenic mice Transgenic mouse transgenic mouse model transmembrane domain transmembrane domains upper and lower respiratory tracts vaccination Vaccine vaccinia virus Ankara vector vectors Viral virus Virus vector weight loss [DOI] 10.1073/pnas.2026785118 PMC 바로가기 [Article Type] 423
Mechanistic transmission modeling of COVID-19 on the Diamond Princess cruise ship demonstrates the importance of aerosol transmission다이아몬드 프린세스 유람선에서 코로나19의 기계적 전파 모델링은 에어로졸 전파의 중요성을 보여줍니다417 Published on 2021-02-232022-08-31 Journal: Proceedings of the National Academy of Sciences of [Category] MERS, 치료제, [키워드] accounted acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition aerosol aerosol transmission Aerosols affected approach assumption built environment close contact condition contributed Control coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 transmission criteria Cruise ship cruise ships cumulative defined diamond Diamond Princess Cruise Ship Disease progression disease transmission Diseases dominant eight Epidemic estimate evaluate Evidence Factors generate greater Health Organization Health Organizations Impact include infected case infected cases Infectious diseases information inhalation iteration Last matrix measure occurred other infectious diseases outbreak Princess public health measure public health measures Quantitative quarantine R 2 reducing reported respiratory respiratory aerosol respiratory droplet Respiratory droplets SARS-CoV-2 severe acute respiratory syndrome Coronavirus Significance Spread Support Transmission transmission factors transmission pathway transmission pathways transmission risk model transmission route Ventilation [DOI] 10.1073/pnas.2015482118 PMC 바로가기 [Article Type] 417
A systems biology approach to COVID-19 progression in population인구의 COVID-19 진행에 대한 시스템 생물학 접근 방식Review Published on 2021-01-012022-09-11 Journal: Advances in protein chemistry and structural biolo [Category] 치료기술, [키워드] applicability applied approach approaches available data China Compartmental models COVID-19 COVID-19 infection COVID-19 progression detection efficiency develop Diseases drastic Effect effective Epidemiology explain explained fatality Gene Expression include Infection infection dynamics Infectious diseases introduced mainland Mass action Mass action law mathematical measure molecular other infectious diseases outbreak overfitting parameter Quantitative biology quarantine Regulation modeling Research SARS-CoV-2 significantly social distancing social distancing measures Systems biology Transmissibility vaccination Wuhan [DOI] 10.1016/bs.apcsb.2021.03.003 PMC 바로가기 [Article Type] Review
Survey of Saliva Components and Virus Sensors for Prevention of COVID-19 and Infectious Diseases코로나19 및 감염병 예방을 위한 타액 성분 및 바이러스 센서 조사Review Published on 2020-12-312022-09-10 Journal: Biosensors [Category] 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 aerosol Aerosols best breathing cause center classification component confirmation Contact Control coronavirus coronavirus disease Coronavirus disease 2019 coughing COVID-19 Dental health detect diabete diabetes diagnose different diseases disease control Diseases droplet droplet detection droplets expelled Health help human saliva Humidity humidity sensor indication indications Infectious disease Infectious diseases Infectious virus infectious viruses knowledge Laboratory lead Measures MONITOR mucosa multi-modal saliva detection other infectious diseases prevention proceed Research resolved respiratory Saliva saliva sensor Sample size SARS-CoV-2 SARS-CoV-2 detection sensitivity sensor severe acute respiratory syndrome Coronavirus sneezing Spread survey talking tissue Transmission United State United States virus virus detection virus sensor viruses water [DOI] 10.3390/bios11010014 PMC 바로가기 [Article Type] Review
Keeping PPE barriers in COVID-19 wards while doing proper auscultation적절한 청진을 수행하는 동안 COVID-19 병동에서 PPE 장벽 유지Commentary Published on 2020-12-092022-09-01 Journal: Antimicrobial Resistance and Infection Control [Category] MERS, SARS, 진단, [키워드] Auscultation Care COVID-19 COVID-19 pandemic COVID-19 patients Diseases equipment Infectious diseases Keeping medical assessment other infectious diseases Personal protective equipment Personal protective equipment (PPE) Physical examination PPE professionals PROTECT Protective Stethoscope [DOI] 10.1186/s13756-020-00854-y PMC 바로가기 [Article Type] Commentary
Immunologic aspects of characteristics, diagnosis, and treatment of coronavirus disease 2019 (COVID-19)코로나바이러스 질병 2019(COVID-19)의 특성, 진단 및 치료의 면역학적 측면Review Published on 2020-06-042022-08-13 Journal: Journal of Biomedical Science [Category] Biochemistry, COVID-19, SARS, [키워드] advancement antibodies Antibody-dependent enhancement approach approaches caused Characteristics component components coronavirus coronavirus disease COVID-19 cytokine Cytokine storm Defense develop Diagnosis Diagnostic method diagnostic methods Diseases evade facilitate Health Organization Host Host immune response host immune responses host immune system immune attack immune response immune responses immune system Immunologic Infection Infectious disease Infectious diseases Inflammatory response Innate immunity knowledge Like Lungs mechanism new strain new strain of coronavirus other infectious diseases pandemic proliferate SARS-CoV SARS-CoV-2 SARS-COV-2 infection Spread susceptible individuals the disease therapeutic agents Therapeutic strategies Treatment vaccination virus viruses World Health Organization [DOI] 10.1186/s12929-020-00663-w PMC 바로가기 [Article Type] Review