New insights into genetic characteristics between multiple myeloma and COVID-19: An integrative bioinformatics analysis of gene expression omnibus microarray and the cancer genome atlas data다발성 골수종과 COVID-19 사이의 유전적 특성에 대한 새로운 통찰력: 유전자 발현 옴니버스 마이크로어레이와 암 게놈 아틀라스 데이터의 통합 생물정보학 분석Comparative Study Published on 2021-12-012022-09-11 Journal: International journal of laboratory hematology [Category] SARS, 유전자 메커니즘, [키워드] 95% CI association bioinformatics Bioinformatics analysis Cancer Characteristics Cohort Control coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 infection Cox regression analysis COX6C Cytochrome C cytochrome c oxidase data set DEGs differentially expressed gene Differentially expressed genes domain downregulated expression Factor Features FIVE Functional enrichment analysis Gene Expression Genetic Genome Hematological malignancy identify independent Infection Microarray Mild mild illness Multiple Multiple myeloma New NOD2 nucleotide oligomerization overall survival Patient performed Prognosis prognostic biomarker Prognostic biomarkers protein-protein interaction screened severe COVID-19 subunit survival upregulated with COVID-19 [DOI] 10.1111/ijlh.13717 PMC 바로가기 [Article Type] Comparative Study
Low-dose whole-lung irradiation in severe COVID-19 pneumonia: a controlled clinical trialRandomized Controlled Trial Published on 2021-12-012022-10-05 Journal: Journal of Medical Radiation Sciences [Category] SARS, 임상, [키워드] 24 hour 28-day mortality benefit caused change changes in chest X-ray control group Controlled clinical trial COVID-19 COVID-19 pandemic COVID-19 patients CXR death determine dose Final IMPROVE low-dose morbidity and mortality Mortality O2 Saturation overall survival oxygen Patient Pneumonia primary endpoint Radiotherapy required Respiratory failure SARS-CoV-2 Secondary endpoints severe COVID-19 severity Shock significantly lower Thromboembolism treated whole-lung irradiation. X-ray [DOI] 10.1002/jmrs.542 PMC 바로가기 [Article Type] Randomized Controlled Trial
Potential benefits of precise corticosteroid therapy for critical COVID-19Article Published on 2021-11-182023-06-15 Journal: Respiratory physiology & neurobiology [Category] MERS, SARS, [키워드] Corticosteroid COVID-19 Lymphocytes overall survival pulmonary fibrosis [DOI] 10.1016/j.resp.2021.103813 PMC 바로가기 [Article Type] Article
Safety and efficacy of autologous non-hematopoietic enriched stem cell nebulization in COVID-19 patients: a randomized clinical trial, Abu Dhabi 2020Research Published on 2021-11-032022-10-29 Journal: Translational Medicine Communications [Category] COVID-19, [키워드] 95% CI Abu adaptive Administered Adverse adverse events approval assessments autologous caused Cell center Clinical improvement Clinical outcome clinical trial cocktail Committee complement conducted Control control group coronavirus disease COVID-19 COVID-19 patients discharge effective Efficacy Emirate event exceptional experimental group hospital immunomodulation improvement include institutional review board Intervention IRB mortality rate Nebulizers and vaporizers occurred Open-label overall survival pandemic Patient patients Peripheral blood primary endpoint Randomized randomized clinical trial receiving Recovery of function reduce reduction reduction in Registered released reported Result Safe Safety SARS-CoV-2 seven-category ordinal scale severity standard care STEM stem cells Symptom therapy Treatment vaccination rates virus [DOI] 10.1186/s41231-021-00101-5 PMC 바로가기 [Article Type] Research
COVID-19 severity and mortality in patients with CLL: an update of the international ERIC and Campus CLL studyCLL 환자의 COVID-19 중증도 및 사망률: 국제 ERIC 및 캠퍼스 CLL 연구의 업데이트Article Published on 2021-11-012022-09-12 Journal: Leukemia [Category] Coronavirus, MERS, SARS, 변종, 유전자 메커니즘, 임상, 진단, 치료법, 치료제, [키워드] Admission age Analysis Campus cardiac failure Case fatality rate category CFR Chronic lymphocytic leukaemia chronic lymphocytic leukemia CLL collected conducted coronavirus disease Coronavirus disease 2019 Course COVID-19 COVID-19 severity death disease disease severity Epidemiology Fatality rate Hospitalization Immunosuppression intensive care intensive care unit International investigated leukemia lower risk Lymphocytic leukemia Mortality older patient older patients outcome overall survival oxygen pandemic Patient retrospective risk factor Risk factors risk of death severe COVID-19 survival susceptible treated Treatment untreated patients [DOI] 10.1038/s41375-021-01450-8 PMC 바로가기 [Article Type] Article
Survival and predictive factors in dialysis patients with COVID-19 in Japan: a nationwide cohort studyResearch Published on 2021-10-212022-10-28 Journal: Renal Replacement Therapy [Category] COVID-19, [키워드] 95% CI addition age albumin Analysis BMI cohort study Committee COVID-19 CRP dialysis disease duration of hospitalization effective Factor force high risk identify increased risk infected patients investigated Japanese Kaplan–Meier method log-rank test Mortality mortality risk Multivariate analysis Nephrology overall survival Patient patients with COVID-19 Peritoneal dialysis Predictive reducing Remdesivir Result risk risk factor SARS-CoV-2 severity significantly higher significantly lower Society statistical analyses statistically significant Stratification survival treated Treatment was increased was performed was used [DOI] 10.1186/s41100-021-00378-0 PMC 바로가기 [Article Type] Research
Clonal hematopoiesis is associated with risk of severe Covid-19클론 조혈은 심각한 Covid-19의 위험과 관련이 있습니다Article Published on 2021-10-132022-09-10 Journal: Nature Communications [Category] MERS, SARS, 변종, 유전자 메커니즘, 진단, 치료기술, [키워드] Acquired advanced age characterized Clostridium Clostridium difficile Cohort consortia disease Genomics Haematopoiesis Hematopoiesis increased risk individual Infection infections Infectious diseases Inflammatory Korean malignant diseases Memorial Mutation outcome overall survival Patient patient data pro-inflammatory profile progenitor cell progenitor cells risk SARS-CoV-2 severe COVID-19 Severe infection severe infections significantly solid tumor somatic mutation somatic mutations survival Tumor [DOI] 10.1038/s41467-021-26138-6 PMC 바로가기 [Article Type] Article
Long-term oncologic outcomes of liver resection for hepatocellular carcinoma in adolescents and young adults: A multicenter study from a hepatitis B virus-endemic areaMulticenter Study Published on 2021-10-012023-06-13 Journal: The American Journal of Surgery [Category] B형 간염, [키워드] adolescents and young adults Hepatectomy Hepatocellular carcinoma overall survival Time-to-recurrence. [DOI] 10.1016/j.amjsurg.2021.03.009 [Article Type] Multicenter Study
Prolonged in-hospital stay and higher mortality after Covid-19 among patients with non-Hodgkin lymphoma treated with B-cell depleting immunotherapyB 세포 고갈 면역 요법으로 치료받은 비호지킨 림프종 환자의 코비드-19 이후 입원 기간 연장 및 사망률 증가Multicenter Study Published on 2021-08-012022-09-11 Journal: American journal of hematology [Category] MERS, SARS, 바이오마커, 진단, [키워드] 95% confidence interval administration Adult patient Adult patients age analyzed anti-CD20 anti-CD20 therapy B-cell contribute death deficiency depleting determinant disease Efficacy Follow-up French hazard ratio higher risk hospital Hospitalization immune immune deficiency Immunotherapy In-hospital Length LOS lymphoma management median median age Mortality multivariable analyses Non-Hodgkin Lymphoma outcomes overall survival pandemic Patient patients patients hospitalized Prolonged question raise risk factor Risk factors subdistribution Support survival therapeutic approaches treated vaccination [DOI] 10.1002/ajh.26209 PMC 바로가기 [Article Type] Multicenter Study
Low-Dose Radiation Therapy for Severe COVID-19 Pneumonia: A Randomized Double-Blind StudyRandomized Controlled Trial Published on 2021-08-012022-10-04 Journal: International journal of radiation oncology, biolo [Category] 임상, [키워드] 95% confidence interval Analysis Arm ARMS changes in Clinicians concealed coronavirus disease COVID-19 Critically ill patient double-blind study Endpoint group groups improve clinical outcome inflammatory markers intensive care low-dose Lymphocyte count mechanical ventilation median median age morbidity and mortality no significant difference overall survival Oxygenation Patient patient cohort Pneumonia postintervention radiation therapy Randomized reduction in secondary secondary endpoint Standard of care survival the primary endpoint treated patient ventilator-free day [DOI] 10.1016/j.ijrobp.2021.02.054 PMC 바로가기 [Article Type] Randomized Controlled Trial