Orthostatic Symptoms and Reductions in Cerebral Blood Flow in Long-Haul COVID-19 Patients: Similarities with Myalgic Encephalomyelitis/Chronic Fatigue SyndromeArticle Published on 2021-12-242022-10-30 Journal: Medicina [Category] COVID-19, SARS, [키워드] age blood flow blood pressure Cardiac index cerebral cerebral blood flow cerebral blood flow (CBF) chronic fatigue syndrome (CFS) clinical phenotypes Control controls COVID-19 COVID-19 case COVID-19 patient COVID-19 patients early-onset fatigue Flow groups healthy controls hemodynamic Long-haul COVID-19 material myalgic encephalomyelitis (ME) no significant difference not different objective orthostatic Orthostatic intolerance overlap Patient patient group patient groups patients physical activity Postural orthostatic tachycardia syndrome (POTS) Prevalence questionnaire reduced reduction reductions in reported response Result SARS-CoV-1 SARS-COV-2 infection significantly Stress Symptom Symptoms syndrome Tachycardia the healthy tilt testing two groups unlikely were used [DOI] 10.3390/medicina58010028 PMC 바로가기 [Article Type] Article
Maternal mortality associated with COVID-19 in Brazil in 2020 and 2021: Comparison with non-pregnant women and men2020 년과 2021 년 브라질에서 Covid-19와 관련된 모체 사망률 : 임신하지 않은 여성 및 남성과의 비교Research Article Published on 2021-12-212022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 변종, [키워드] acute respiratory syndrome Brazil caused collected data Comorbidity COVID-19 COVID-19 pandemic database death deaths Desaturation Diagnosis epidemiological greater groups higher risk include intensive care intubation leads Maternal men Mortality mortality rate objective Patient patient groups Postpartum Pregnancy pregnant presenting respiratory Result risk risk factor Severe case severe COVID-19 stratified surveillance data Transmissibility variant virulence with COVID-19 women [DOI] 10.1371/journal.pone.0261492 PMC 바로가기 [Article Type] Research Article
Passive immune therapies: another tool against COVID-19수동 면역 요법: COVID-19에 대한 또 다른 도구Review Published on 2021-12-102022-09-11 Journal: Hematology. American Society of Hematology. Educat [Category] SARS, 진단, 치료제, [키워드] absence acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 approval benefit Casirivimab convalescent plasma coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Emergency use Evidence fatal COVID-19 Globulin high risk hyperimmune hyperimmune globulin immune immune system Infection Japan lack Mild mild to moderate Mild to moderate COVID-19 Moderate COVID-19 monoclonal neutralizing monoclonal antibodies other treatment pandemic Passive Patient patient groups performed Prevent Regulatory required Research respiratory respiratory infections SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe respiratory infections Therapies therapy treat Treatment United Kingdom [DOI] 10.1182/hematology.2021000299 PMC 바로가기 [Article Type] Review
Longitudinal Cytokine Profile in Patients With Mild to Critical COVID-19경증에서 중요한 코비드 -19 환자의 종 방향 사이토 카인 프로파일Observational Study Published on 2021-12-062022-08-31 Journal: Frontiers in Immunology [Category] SARS, 바이오마커, 임상, [키워드] Administered adult COVID-19 patient adult COVID-19 patients ARDS association best Biomarker blood sample Blood samples chemokine clinical endpoint Clinical endpoints coronavirus coronavirus disease Coronavirus disease 2019 correlated COVID-19 Critically ill critically ill patients cytokine cytokine profile Cytokine release syndrome Cytokines disease severity dose early phase elevated evaluate followed by gamma interferon growth highest Hong Kong Hospitalized host response IL-10 IL-1ra IL-5 IL-6 IL-8 immune Inflammation intensive care interferon interferon-induced protein interleukin IP-10 late phase longitudinal Macrophage MCP-1 mDC mechanical ventilation MIG Mild MIP-1α moderate monocyte monocyte chemoattractant protein-1 monokine Norepinephrine observational study Patient patient group patient groups patients predict predicted profile proinflammatory prospective observational study public hospitals receptor receptor antagonist SARS-CoV-2 Seven severity symptom onset was performed with COVID-19 [DOI] 10.3389/fimmu.2021.763292 PMC 바로가기 [Article Type] Observational Study
Analyzing the impact of machine learning and artificial intelligence and its effect on management of lung cancer detection in covid-19 pandemicResearch article Published on 2021-12-032022-10-05 Journal: Sensors (Basel, Switzerland) [Category] 치료기술, [키워드] Accuracy Algorithm Algorithms alteration artificial intelligence boost Cancer cancer patient Care clinical trial Combination consequence COVID-19 COVID-19 epidemic COVID-19 patient Critical CT scan CT scans detect Diagnosis effective Epidemic Epidemiology example help identify immune systems Immunotherapy implementation individual investigated lung lung cancer machine learning machine learning algorithm management medication molecular offer pandemic patient groups Pneumonia positive patient produced Radiation recruited Research researcher specificity susceptible Techniques Therapies therapy time-consuming Treatment utilised variety virus was done with COVID-19 [DOI] 10.1016/j.matpr.2021.11.549 [Article Type] Research article
Is There a Link between Circadian Clock Protein PERIOD 3 (PER3) (rs57875989) Variant and the Severity of COVID-19 Infection?일주기 시계 단백질 PER3(PER3)(rs57875989) 변이체와 COVID-19 감염의 심각도 사이에 연관성이 있습니까?Article Published on 2021-12-012022-09-11 Journal: Current medical science [Category] SARS, 변종, [키워드] circadian rhythm CLOCK Comorbidity Control Corona corona virus disease 2019 correlation Course COVID-19 COVID-19 patients diagnosed with COVID-19 distribution dysregulation Effect event examined Follow-up Genotype guide healthy control healthy controls hospital Host immune system initial gene intensive care Mortality no significant difference Patient patient groups PER3 polymorphism Prognosis recruited significant difference significantly higher significantly more statistical significance subgroup the healthy the patient Virus Disease Volunteer [DOI] 10.1007/s11596-021-2442-y PMC 바로가기 [Article Type] Article
Comparison of an inactivated Covid19 vaccine-induced antibody response with concurrent natural Covid19 infection비활성화된 Covid19 백신 유도 항체 반응과 동시 자연 Covid19 감염의 비교Article Published on 2021-12-012022-09-11 Journal: International Journal of Infectious Diseases [Category] SARS, 진단, 치료기술, [키워드] age Anti-N anti-N antibodies anti-N antibody anti-S Anti-S1 antibodies antibody Antibody Response Antibody testing Antibody titer Antibody titers both groups COVID-19 infection COVID19 decrease detect disadvantage ELISA enrolled Euroimmun Gender Germany group HCW HCWs Health care Health care worker health care workers IgG inactivated increase in Infection median value median values Patient patient group patient groups positive correlation reported risk Roche SARS-CoV-2 Seroconversion statistically significant statistically significant difference the antibody the antibody response the patient the vaccine total Ig vaccinated individual vaccinated individuals vaccination Vaccine vaccine-induced antibody response were used [DOI] 10.1016/j.ijid.2021.09.060 PMC 바로가기 [Article Type] Article
Safety and efficacy of the mRNA BNT162b2 vaccine against SARS-CoV-2 in five groups of immunocompromised patients and healthy controls in a prospective open-label clinical trial5 개의 면역 저하 환자 및 전향 적 개방형 임상 시험에서 건강한 대조군에서 SARS-COV-2에 대한 mRNA BNT162B2 백신의 안전성 및 효능Research paper Published on 2021-11-302022-08-13 Journal: EBioMedicine [Category] MERS, SARS, 임상, [키워드] Adverse adverse events Adverse reaction Allogeneic allogeneic hematopoietic stem cell transplantation Antibody titre antibody titres BNT162b2 BNT162b2 mRNA BNT162b2 mRNA vaccination CAR T, Chimeric antigen receptor T CAR-T Cell Cell therapy certain immunocompromised patient groups chronic lymphocytic leukemia clinical trial clinical trials CLL CLL, Chronic lymphocytic leukemia Control controls Council COVID-19, Coronavirus disease 2019 disorder Efficacy event excluded finding FIVE five group foundation funding generally mild group healthy control healthy controls Hematopoietic stem cell highlight HIV HIV, Human immunodeficiency virus HSCT, Allogeneic hematopoietic stem cell transplantation Human immunodeficiency virus human stem-cell transplantation Ibrutinib Immunity Immunocompromised Immunocompromised patient immunocompromised patient group Immunocompromised patients immunodeficiency disorder immunodeficiency disorders IMPROVE Infection ITT, Intention to treat Knut leukemia Lymphocytic leukemia mPP, Modified per protocol mRNA BNT162b2 vaccine mRNA vaccination mycophenolate mycophenolate mofetil occurred of BNT162b2 Open-label organ transplantation organization organizations Patient patient group patient groups PID, Primary immunodeficiency disorders PP, Per protocol primary endpoint Primary Immunodeficiency Prospective clinical trial Rate Region Safe Safety SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2, Severe acute respiratory syndrome coronavirus 2 second dose secondary endpoint Secondary endpoints selected serious adverse reaction Seroconversion seroconversion rate seroconverted solid organ solid organ transplantation SOT SOT, Solid organ transplantation stem cell subgroups subject Swedish T cell therapy Treatment vaccination against COVID-19 vaccine dose virus infection [DOI] 10.1016/j.ebiom.2021.103705 PMC 바로가기 [Article Type] Research paper
Assessing Values and Preferences Toward SARS-CoV-2 Self-testing Among the General Population and Their Representatives, Health Care Personnel, and Decision-Makers: Protocol for a Multicountry Mixed Methods StudyProtocol Published on 2021-11-262022-10-29 Journal: JMIR Research Protocols [Category] COVID-19, [키워드] accelerate Accessibility Analysis analyzed Assessing Care coded Community Complete conducted counseling country COVID-19 cross-sectional survey Decision-making determine diagnose diagnostic dissemination effective enrolled Enrollment event General population Health Health care worker health care workers health system Identifier identify India Indonesia infected individual inquiry Kenya Laboratory lack Local Mixed methods multisite National Nigeria objective participant patient groups Population preference Prevent protocol provide quarantine raise report response Result Safe SARS-CoV-2 SARS-CoV-2 testing Screening self-testing South specificity Spread Surveillance Testing transcribed Transmission value widespread [DOI] 10.2196/33088 PMC 바로가기 [Article Type] Protocol
Socioeconomic deprivation and ethnicity inequalities in disruption to NHS hospital admissions during the COVID-19 pandemic: a national observational studyObservational Study Published on 2021-11-252022-10-04 Journal: BMJ Quality & Safety [Category] MERS, 임상, [키워드] 95% CI Admission Area calculated Care conducted country COVID-19 COVID-19 emergency COVID-19 pandemic Deprivation determine Diagnosis England English exacerbating explained Health Health policy Health services research Healthcare system hospital Hospital admission Linear regression analysis Local mechanism Multiple National National Health Service NHS Non-COVID-19 Patient patient groups Population prevalence of COVID-19 reduction in reductions in Result risk Socioeconomic deprivation Spread Volume was used Weekly while [DOI] 10.1136/bmjqs-2021-013942 PMC 바로가기 [Article Type] Observational Study