Current Pharmaceutical Aspects of Synthetic Quinoline Derivativesarticle Published on 2021-12-312024-09-01 Journal: Mini-Reviews in Medicinal Chemistry [Category] 말라리아, [키워드] biologically active broad spectrum Heterocyclic inhibition pharmaceutical Quinoline derivatives [Article Type] article
Molecular Docking and Dynamics Investigations for Identifying Potential Inhibitors of the 3-Chymotrypsin-like Protease of SARS-CoV-2: Repurposing of Approved Pyrimidonic Pharmaceuticals for COVID-19 TreatmentSARS-COV-2의 3- chymotrypsin- 유사 프로테아제의 잠재적 억제제를 식별하기위한 분자 도킹 및 역학 조사 : Covid-19 치료를위한 승인 된 피리 미도 론적 제약의 재구성Article Published on 2021-12-092022-08-31 Journal: Molecules [Category] SARS, 신약개발, 치료제, [키워드] 3-chymotrypsin-like protease 3CL pro active site active sites approved binding binding affinity binding energy binding free energy catalytic catalytic dyad chymotrypsin citicoline complexes conformation coronavirus SARS-CoV-2 COVID-19 Cys145 cytarabine determined by docked complex drug Drug administration Dynamics Floxuridine food free energy His41 identifying inhibitory effect investigation involved lamivudine molecular molecular docking molecular dynamics molecular dynamics simulations Molecular mechanics mustard pharmaceutical Potential protease pyrimidonic pharmaceuticals ranged repurposing residue residues SARS-CoV-2 stability stavudine surface area telbivudine tested tipiracil trifluridine uracil uracil mustard uridine uridine triacetate US Food and Drug Administration zalcitabine [DOI] 10.3390/molecules26247458 PMC 바로가기 [Article Type] Article
LB9. Longitudinal antibody dynamics in children infected with SARS-CoV-2 through 6 months post-infectionLate Breaker Abstracts Published on 2021-11-042022-10-29 Journal: Open Forum Infectious Diseases [Category] COVID-19, [키워드] Abbott acute respiratory syndrome antibody Antibody titer Architect AstraZeneca binding Blood blood sample CDC changes in children collected Community consultant convalescent sera coronavirus COVID-19 vaccine decrease detectable Diagnosis elicit enrolled evaluate examined figure Flagship GlaxoSmithKline had no Hospitalized Immunocompromised Immunosuppression include infected with SARS-CoV-2 Infection Jesse laboratory-confirmed SARS-CoV-2 infection longitudinal Meissa Moderna neutralization potency neutralization titer Neutralizing Neutralizing activity neutralizing titers nucleocapsid Outpatient participant Pfizer pharmaceutical Post-infection Protein provided recruited reduction Result Sanofi Pasteur SARS-CoV-2 SARS-CoV-2 immunity Seattle Children’s Hospital supported symptomatic and asymptomatic symptomatic disease undetectable Viral protein Volunteer were assessed with COVID-19 [DOI] 10.1093/ofid/ofab466.1640 PMC 바로가기 [Article Type] Late Breaker Abstracts
Quaternary Ammonium Compounds: Bioaccumulation Potentials in Humans and Levels in Blood before and during the Covid-19 Pandemic4차 암모늄 화합물: 코비드-19 팬데믹 이전과 동안 인간의 생물학적 축적 가능성과 혈액 내 수준Article Published on 2021-11-022022-09-11 Journal: Environmental science & technology [Category] SARS, 치료기술, 치료제, [키워드] Ammonium Analysis binding Bioaccumulation Biomonitoring Blood blood sample Blood samples build clearance rate collected Compound Concentration consumer COVID-19 COVID-19 pandemic Disinfectants epidemiological experiments group Human In vitro−in vivo extrapolation (IVIVE) in vivo information Level median metabolism outbreak pandemic pharmaceutical Potential Protein binding Quaternary ammonium compounds (QACs). risk Risk assessment sera Serum protein significantly higher these compound these compounds variety [DOI] 10.1021/acs.est.1c01654 PMC 바로가기 [Article Type] Article
Implementation of a novel home delivery service during pandemicArticle Published on 2021-11-012023-07-05 Journal: European Journal of Hospital Pharmacy [Category] SARS, [키워드] economics hospital hospital distribution systems medication systems pharmaceutical pharmaceutical preparations pharmacy service [DOI] 10.1136/ejhpharm-2020-002500 PMC 바로가기
Understanding Quality Paradigm Shifts in the Evolving Pharmaceutical Landscape: Perspectives from the USP Quality Advisory Group진화하는 제약 환경에서 품질 패러다임 변화 이해 : USP 품질 자문 그룹의 관점Review Published on 2021-10-152022-08-31 Journal: The AAPS Journal [Category] MERS, 치료제, [키워드] adoption Advanced manufacturing Analytical procedures lifecycle approach approaches changes in collaboration complement COVID-19 crisis data management Digital technologies and performance-based standards flexible focus Globalization group help increasingly lifecycle organization paradigm Paradigm Shifts pharmaceutical pharmaceutical industry procedure product promote Quality recent recognize Regulatory Resilience Risk-based quality management systems shift Supply chain Therapies understanding USP utilization [DOI] 10.1208/s12248-021-00634-5 PMC 바로가기 [Article Type] Review
Pharmaceutical Industry’s Engagement in the Global Equitable Distribution of COVID-19 Vaccines: Corporate Social Responsibility of EUL Vaccine DevelopersArticle Published on 2021-10-152022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] acting analyzed category clinical trial contribute corporate social responsibility COVAX COVID-19 COVID-19 vaccine distribution Effectiveness Engagement examined Final global health help indicated inequality management methodology pandemic Participation pharmaceutical pharmaceutical companies Research responsibility significantly Vaccine Vaccine developer Vaccines were measured were used [DOI] 10.3390/vaccines9101183 PMC 바로가기 [Article Type] Article
Flatten the curve: Empirical evidence on how non-pharmaceutical interventions substituted pharmaceutical treatments during COVID-19 pandemic곡선을 평평하게하십시오 : Covid-19 Pandemic 동안 비 약공 개입이 어떻게 제약 치료를 대체했는지에 대한 경험적 증거Research Article Published on 2021-10-112022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 치료제, [키워드] Additive Additive Model Affect Analysis balance COVID-19 COVID-19 pandemic death rate Demographic variables Economy Effect effective empirical evidence Generalized Government growth Impact intervene Intervention lockdown Model New outbreak pharmaceutical Rate reduced Research risk specific rate spread of COVID-19 suppress Treatment university [DOI] 10.1371/journal.pone.0258379 PMC 바로가기 [Article Type] Research Article
Mental Health Services Data Dashboards for Reporting to Australian Governments during COVID-19Brief Report Published on 2021-10-072022-10-29 Journal: International Journal of Environmental Research an [Category] Coronavirus, MERS, SARS, [키워드] comparison COVID-19 Dashboard Demand Department Government information Medicare Mental mental health mental health service organization organizations pandemic pharmaceutical Reporting Research schedule service services Support Welfare [DOI] 10.3390/ijerph181910514 PMC 바로가기 [Article Type] Brief Report
European collaborations on medicine and vaccine procurementPolicy & Practice Published on 2021-10-012022-10-27 Journal: Bulletin of the World Health Organization [Category] COVID-19, [키워드] access activity challenge coronavirus disease country COVAX COVID-19 COVID-19 vaccine distribution effort Europe European European country Forum Health health-care system IMPROVE increasingly initiative involved joint knowledge mechanism mechanisms Medicine Medicines pandemic pharmaceutical Region risk Vaccine Vaccines Volume [DOI] 10.2471/BLT.21.285761 PMC 바로가기 [Article Type] Policy & Practice