Breath-holding physiology, radiological severity and adverse outcomes in COVID-19 patients: A prospective validation studyArticle Published on 2022-12-012023-07-10 Journal: Respirology (Carlton, Vic.) [Category] COVID19(2023년), [키워드] breath-holding procedure coronavirus disease COVID-19 incident adverse outcome mean desaturation Physiology radiological severity. [DOI] 10.1111/resp.14336 PMC 바로가기
From novel discovery tools and biomarkers to precision medicine-basic cardiovascular science highlights of 2021/22Article Published on 2022-10-212022-11-15 Journal: Cardiovascular Research [Category] 바이오마커, 유전자 메커니즘, [키워드] Anti-viral therapy approaches Atherosclerosis basic Basic science Biomarker Biomarkers Cardiac arrhythmia Cardiology cardiovascular cardiovascular system Cell Community Council COVID-19 demonstrated disease driving European extracellular vesicle Genetic polymorphism highlight Inflammation knowledge mechanism Medicine molecular molecular basis non-coding RNA pathogenic Personalized medicine Physiology Precision precision medicine Prize PROTECT Protective responses Science single-cell Society syndrome thrombotic complication Vascular [DOI] 10.1093/cvr/cvac114 PMC 바로가기
Mechanical ventilation in COVID-19: A physiological perspectiveReview Published on 2022-07-012023-07-06 Journal: Experimental Physiology [Category] COVID19(2023년), [키워드] artificial COVID-19 Critical care Physiology Respiration respiratory Respiratory distress syndrome SARS-CoV-2 [DOI] 10.1113/EP089400 PMC 바로가기 [Article Type] Review
Acute kidney injury in patients with COVID-19 in the intensive care unit: evaluation of risk factors and mortality in a national cohortObservational Study Published on 2022-06-232022-10-05 Journal: BMJ Open [Category] 임상, [키워드] 30-Day mortality acute renal failure Admission admitted to ICU adult intensive & Adult patient AKI Analysis Chronic kidney disease CKD Cohort COVID-19 Critical Critical care defined hospital Hospital admission ICU ICU admission ill patient incidence indicate Intensive intensive care Kidney injury Mortality National Norway outcome outcome measure patients with COVID-19 Physiology populations predictor Prevalence registry renal risk risk factor score secondary secondary outcome study population survival the patient was related were excluded with COVID-19 [DOI] 10.1136/bmjopen-2021-059046 PMC 바로가기 [Article Type] Observational Study
Investigation of the use of a sensor bracelet for the presymptomatic detection of changes in physiological parameters related to COVID-19: an interim analysis of a prospective cohort study (COVI-GAPP)COVID-19와 관련된 생리적 매개변수의 변화를 무증상으로 감지하기 위한 센서 팔찌의 사용 조사: 전향적 코호트 연구(COVI-GAPP)의 중간 분석Randomized Controlled Trial Published on 2022-06-212022-09-11 Journal: BMJ Open [Category] COVID19(2023년), MERS, SARS, 임상, 진단, 치료기술, [키워드] age Algorithm Analysis baseline changes in cohort study COVID-19 diagnosed FIVE health & health informatics heart rate HRV Incubation infection control Interim interim analysis investigated investigation memory molecular National parameter participant Participants physiological Physiology positive presymptomatic prospective cohort study Public public health random randomised recall Recurrent Neural Network registration number respiratory rate Safety SARS-COV-2 infection selected sensitivity serological assays setting Short-Term Memory significant changes in symptom onset symptomatic temperature training set Trial Variability Virology were recorded [DOI] 10.1136/bmjopen-2021-058274 PMC 바로가기 [Article Type] Randomized Controlled Trial
Integrative metabolomic and proteomic signatures define clinical outcomes in severe COVID-19Research article Published on 2022-06-172022-10-05 Journal: iScience [Category] 바이오마커, 임상, [키워드] Analysis Biological sciences Clinical finding Clinical outcome clinical outcomes collagen Concordance controls Coronavirus disease-19 COVID-19 COVID-19 disease severity COVID-19 patient cross talk disease global healthcare Hospitalized human metabolism immune modulation independent datasets Interaction Medicine metabolism metabolite metabolomic metabolomics molecular morbidity morbidity and mortality Mortality nucleotide outcome measure pandemic pathogenic performed Physiology predict predictive power Protein proteomic serum severe COVID-19 severe disease vascular homeostasis [DOI] 10.1016/j.isci.2022.104612 [Article Type] Research article
Role of procalcitonin as a predictor of clinical outcomes in hospitalized patients with COVID-19Research article Published on 2022-06-012022-10-05 Journal: International Journal of Infectious Diseases [Category] 바이오마커, [키워드] Admission analyzed C-reactive protein chronic clinical Clinical outcome clinical outcomes correlation COVID-19 demographic data demonstrated determine elevated Evidence group groups hospital hospitalized patient ICU in-hospital mortality inclusion criteria intensive care Kaplan-Meier analysis Laboratory logistic regression model Mortality multivariable objective Patient patients hospitalized PCT Physiology procalcitonin Prognosis Result role severity significantly statistical were used with COVID-19 [DOI] 10.1016/j.ijid.2022.03.044 [Article Type] Research article
[Optimal oxygen administration-new evidence from treating COVID-19?][최적의 산소투여-코로나19 치료의 새로운 증거?]Review Published on 2022-06-012022-09-11 Journal: Medizinische Klinik, Intensivmedizin Und Notfallme [Category] 치료제, [키워드] activate Cell cells changes in Clinical practice compensatory mechanism compensatory mechanisms coronavirus disease Coronavirus disease 2019 COVID-19 disorders English environmental factors Evidence functional Gang highlight human body human cells hypoxia Injury integrity invasive knowledge Lactates mechanism organ damage organ systems oxygen Oxygen consumption oxygen levels oxygen saturation Oxygenation pandemic pathophysiology physiological mechanism Physiology Prevent remain unchanged risk Side effect survival target therapeutic strategy therapy [DOI] 10.1007/s00063-022-00914-8 PMC 바로가기 [Article Type] Review
Cytomegalovirus blood reactivation in COVID-19 critically ill patients: risk factors and impact on mortalityObservational Study Published on 2022-06-012022-10-05 Journal: Intensive care medicine [Category] COVID19(2023년), SARS, 임상, [키워드] 95% CI acute respiratory distress adjusted Adjusted analysis affected association Blood CMV coronavirus disease COVID-19 Cox proportional hazard Critically ill Critically ill patient cytomegalovirus Cytomegalovirus reactivation Effect evaluated Hospital mortality ICU ICU admission ICU patient incidence increased risk intensive care Invasive mechanical ventilation large cohort Mechanical mechanical ventilation Mortality Occurrence outcome Patient Physiology Platelet Quantitative regression models risk factor SARS-COV-2 infection score screened secondary bacterial infection Sepsis severity syndrome worsening [DOI] 10.1007/s00134-022-06716-y PMC 바로가기 [Article Type] Observational Study
SARS-CoV-2 Virion Infectivity and Cytokine Production in Primary Human Airway Epithelial Cells1차 인간 기도 상피 세포에서 SARS-CoV-2 비리온 감염성과 사이토카인 생산Article Published on 2022-05-022022-09-11 Journal: Viruses [Category] COVID19(2023년), SARS, 변종, [키워드] Activation Alpha B.1.1.529 B.1.1.7 B.1.351 B.1.617.2 BavPat1 Behavior Beta Cell cultures cytokine D614G mutation epithelial epithelial cell epithelial cells Evidence Ex vivo hAEC Human human airway human airway epithelial infect Infectivity Innate immunity isolate lack Lineage lineages new SARS-CoV-2 no difference observé Omicron variant Omicron variants organotypic model Physiology primary human airway Primary human airway epithelial cells Production provide replacement replicate respiratory tissue respiratory tissues SARS-CoV-2 SARS-CoV-2 variants variant variants variants of concern virion virus vRNA [DOI] 10.3390/v14050951 PMC 바로가기 [Article Type] Article