The role of natural products from medicinal plants against COVID-19: traditional medicine practice in TanzaniaResearch article Published on 2022-06-152022-10-05 Journal: Heliyon [Category] 치료제, [키워드] acute respiratory syndrome antiviral activity antiviral agent antiviral drug antiviral drugs Antiviral medications caused collected compounds COVID-19 discharge disease disrupting effort Eucalyptus exhibiting fatty acids Host Identified identify involved medicinal plants New coronavirus obligatory other coronaviruses Phytochemical screening phytochemicals plant plants practitioners Replication researcher Result Saponin SARS-CoV-2 secondary metabolites Steroids Support targets Vaccine viral life cycle [DOI] 10.1016/j.heliyon.2022.e09739 [Article Type] Research article
Virtual screening, ADMET profiling, PASS prediction, and bioactivity studies of potential inhibitory roles of alkaloids, phytosterols, and flavonoids against COVID-19 main protease (Mpro)Article Published on 2022-06-012023-07-06 Journal: Natural Product Research [Category] COVID19(2023년), [키워드] COVID-19 density functional method molecular docking phytochemicals SARS-CoV-2 Virtual screening [DOI] 10.1080/14786419.2021.1935933 PMC 바로가기
Nutrition as a key to boost immunity against COVID-19Review Published on 2022-06-012023-07-09 Journal: Clinical nutrition ESPEN [Category] COVID19(2023년), [키워드] Anti-inflammatory antioxidant macronutrients micronutrients phytochemicals [DOI] 10.1016/j.clnesp.2022.04.007 PMC 바로가기 [Article Type] Review
Phytochemicals-based targeting RdRp and main protease of SARS-CoV-2 using docking and steered molecular dynamic simulation: A promising therapeutic approach for Tackling COVID-19Research article Published on 2022-06-012022-10-05 Journal: Computers in biology and medicine [Category] COVID19(2023년), SARS, 치료제, [키워드] affected antiviral drug approved binding binding pocket caused complexes computational tool COVID-19 COVID-19 pandemic docking inhibitor Interaction knowledge Ligand Main proteases mechanism molecular molecular docking molecular dynamic simulation Molecular dynamics simulation MPro mutated phytochemicals protease Protein RdRP RNA-dependent RNA polymerase SARS-CoV-2 Side effect stability Steered dynamic simulation strain suggested targets therapeutic Therapeutic approach therapeutic efficacy Vaccine vaccine candidate virus [DOI] 10.1016/j.compbiomed.2022.105468 [Article Type] Research article
Antiviral Efficacy of Selected Natural Phytochemicals against SARS-CoV-2 Spike Glycoprotein Using Structure-Based Drug Designing구조 기반 약물 설계를 사용한 SARS-CoV-2 스파이크 당단백질에 대한 선택된 천연 파이토케미컬의 항바이러스 효능Article Published on 2022-04-082022-09-11 Journal: Molecules [Category] COVID19(2023년), SARS, 치료제, [키워드] Absorption ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis binding binding affinity Bioavailability candidate Compound conducted Coronaviral coronavirus coronavirus disease Coronavirus disease 2019 CoV COVID-19 crystal structure database disease distribution docked docked complex docked complexes drug drug candidate drug targets Effectiveness Environment excretion flavonoid Health host cells Immunological response library metabolism milk molecular molecular docking molecular dynamic simulation molecular interaction MPD3 natural pandemic PDB penetrate pharmacological target Phylloflavan phytochemical phytochemicals Protein PubChem Receptor binding domain S-RBD SARS-CoV-2 selected severe acute respiratory syndrome Coronavirus Sickness silico studies silico study spike spike glycoprotein Spike protein subgroups thistle Virtual screening virulent was obtained Zinc [DOI] 10.3390/molecules27082401 PMC 바로가기 [Article Type] Article
Repurposing of phytomedicine-derived bioactive compounds with promising anti-SARS-CoV-2 potential: Molecular docking, MD simulation and drug-likeness/ADMET studiesResearch article Published on 2022-04-012022-10-05 Journal: Saudi Journal of Biological Sciences [Category] 신약개발, [키워드] active against anti-SARS-CoV-2 approach binding mode Compound computational method COVID-19 database docking Drug repurposing effective Efficacy Enzymes in silico inhibitor inhibitory effect initial management MD simulation molecular docking molecular dynamics Molecular dynamics simulation MPro notable phytochemicals Phytomedicine PLPro polymerase protease RdRP repurposing SARS-CoV-2 SARS-COV-2 infection screened selected steroid therapeutic target Toxicity [DOI] 10.1016/j.sjbs.2021.12.018 [Article Type] Research article
Viral Hepatitis, Cholesterol Metabolism, and Cholesterol-Lowering Natural CompoundsReview Published on 2022-03-312023-06-01 Journal: International Journal of Molecular Sciences [Category] A형 간염, Fulltext, [키워드] cholesterol metabolism Hepatitis virus HMG-CoA reductase phytochemicals [DOI] 10.3390/ijms23073897 PMC 바로가기 [Article Type] Review
Genus Sophora : a comprehensive review on secondary chemical metabolites and their biological aspects from past achievements to future perspectivesReview Published on 2021-12-152024-09-02 Journal: Archives of pharmacal research [Category] 대상포진, [키워드] biological activities Distinctive-alkaloids Fabaceae phytochemicals Sophora [DOI] 10.1007/s12272-021-01354-2 PMC 바로가기 [Article Type] Review
Pharmacological Applications and Action Mechanisms of Phytochemicals as Alternatives to Antibiotics in Pig ProductionReview Published on 2021-12-092023-08-30 Journal: Frontiers in Immunology [Category] E형 간염, [키워드] alternatives Antibiotics pharmacological applications and action mechanisms phytochemicals pig production [DOI] 10.3389/fimmu.2021.798553 PMC 바로가기 [Article Type] Review
Combination of natural antivirals and potent immune invigorators: A natural remedy to combat COVID-19천연 항바이러스제와 강력한 면역 강화제의 조합: COVID-19 퇴치를 위한 천연 치료제Review Published on 2021-12-012022-09-11 Journal: Phytotherapy research : PTR [Category] SARS, 치료제, [키워드] absence acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 anti-SARS-CoV-2 antiviral therapy antivirals assembly attachment B-cells baicalin blocking virus entry booster caffeic acid Chloroquine chrysin clinical investigation compounds coronavirus COVID-19 cytokine production drugs effective Effectiveness exacerbating Favipiravir flare flavin Free radicals gallic acid glycyrrhizin Health herbacetin host cell host cell receptor immune immune system immunostimulants Immunosuppressive agents include inhibiting inhibiting viral replication iron management mechanism natural natural antiviral Neutralizing Neutrophils phytochemicals plant Prevent proliferation Remdesivir SARS-CoV-2 severe acute respiratory syndrome Coronavirus situation Spread T-cells targets theaflavin Transmission unique Vaccine Validity viral replication virus entry vitamins Wuhan Wuhan, China Zinc [DOI] 10.1002/ptr.7228 PMC 바로가기 [Article Type] Review