SARS-CoV-2 virus label-free electrochemical nanohybrid MIP-aptasensor based on Ni 3(BTC) 2 MOF as a high-performance surface substrate고성능 표면 기판으로 Ni 3(BTC) 2 MOF 기반 SARS-CoV-2 바이러스 표지 없는 전기화학 나노하이브리드 MIP-aptasensorArticle Published on 2022-07-192022-09-11 Journal: Mikrochimica Acta [Category] COVID19(2023년), SARS, 치료기술, [키워드] aptamer BTC carbon Concentration Detection limit Dopamine electrochemical biosensor facilitated growth In situ Ni3(BTC)2 MOF increase in linear relationship MIP MOF molecular Molecularly imprinted polymer Polymer S protein SARS-CoV-2 SARS-CoV-2 S SARS-CoV-2 S protein SARS-CoV-2 virus SARS-CoV-2, covid 19. Screen selective the SARS-CoV-2 virus transfer virus [DOI] 10.1007/s00604-022-05357-8 PMC 바로가기 [Article Type] Article
Nanoparticle-delivered TLR4 and RIG-I agonists enhance immune response to SARS-CoV-2 subunit vaccine나노입자 전달 TLR4 및 RIG-I 작용제는 SARS-CoV-2 소단위 백신에 대한 면역 반응을 향상시킵니다Article Published on 2022-07-012022-09-11 Journal: Journal of controlled release : official journal o [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] activated Adaptive immune response adjuvant adjuvants agonist Anti-spike anti-Spike IgG Antibody titer Antibody titers Antigen antigen-presenting cell antigen-presenting cells APC APCS B cell B cells BAL Bcl6 Blood bronchoalveolar CD4 CD44 Cell cell population characterized Combination adjuvant COVID-19 COVID-19 protein subunit vaccine CpG DLNs draining lymph node draining lymph nodes Efficacy ENhance follicular Germinal center GL7 helper cell humoral immune responses IgA IgG immune immune response immune responses Immunity IMPROVE in vitro in vivo Increases increases in Infection intramuscular intramuscular vaccination intranasal Intranasal versus intramuscular vaccination intranasally lead lung Lungs lymphocyte memory T memory T cell mice molecular Monophosphoryl lipid A MPLA Native neutralizing antibody titers Pattern recognition pattern recognition receptor Pattern recognition receptors Polymer Population Proinflammatory cytokine Protein subunit protein subunit vaccine Protein subunit vaccines PRR PRRs PUUC reaction receptor receptors responses against retinoic acid retinoic acid-inducible gene I RIG-I robust S1 subunit SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike protein secretion spike IgA Spike protein stabilized spike protein stimulate subunit Subunit vaccine T cell T cell proliferation the S1 subunit TLR TLR4 TLR7 TLR7/8 TLR9 TLRs Toll-like receptor Toll-like receptors Transmission unique Vaccine vaccine availability vaccine responses variants [DOI] 10.1016/j.jconrel.2022.05.023 PMC 바로가기 [Article Type] Article
Structural colour enhanced microfluidics Research Published on 2022-05-192022-10-05 Journal: Nature Communications [Category] 진단, [키워드] advance characterized demonstrated dependent on flexible independent intrinsic organized Polymer reduction shown [DOI] 10.1038/s41467-022-29956-4 [Article Type] Research
Evaluation of electropolymerized molecularly imprinted polymers (E-MIPs) on disposable electrodes for detection of SARS-CoV-2 in saliva타액에서 SARS-CoV-2 검출을 위한 일회용 전극의 전기중합 분자 각인 폴리머(E-MIP) 평가Article Published on 2022-05-082022-09-11 Journal: Analytica chimica acta [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] absence biosensor capture COVID-19 COVID-19 negative crosslinked demonstrated Electrochemical impedance spectroscopy Electrochemical polymerization evaluated functional isothermal LAMP limit of detection log Molecularly imprinted polymers monoclonal antibody monomer N,N'-methylenebisacrylamide National Health Service nine nucleic acid nucleic acid amplification Other respiratory viruses Patient PCA Polymer positive positive sample Principal component principal component analysis pseudoparticle respiratory respiratory viruses Saliva saliva samples SARS-CoV-2 selective selectivity specificity threshold threshold value transfer Treatment UK National Health Service virus [DOI] 10.1016/j.aca.2022.339777 PMC 바로가기 [Article Type] Article
Molecularly Imprinted Polymer Nanoparticles Enable Rapid, Reliable, and Robust Point-of-Care Thermal Detection of SARS-CoV-2분자 각인 고분자 나노 입자로 SARS-CoV-2의 신속하고 신뢰할 수 있으며 강력한 현장 진료 열 감지 가능Article Published on 2022-04-222022-09-11 Journal: ACS Sensors [Category] COVID19(2023년), SARS, 변종, 진단, 치료기술, [키워드] Acidic addition affinity Alpha amino acids antibody Antigen biosensors condition COVID-19 detection Detection limit diagnostic diagnostic testing elevated temperature epitope heat heat transfer heat transfer method (HTM) lack media molecularly imprinted polymer nanoparticles (nanoMIPs) nanoparticle Patient point-of-care point-of-care testing Polymer Population screening Rapid rapid antigen test Rapid antigen tests receptors SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-CoV-2 antigens sensitivity Sensitivity and specificity Spike protein temperature the spike protein thermal transfer variant variants [DOI] 10.1021/acssensors.2c00100 PMC 바로가기 [Article Type] Article
Capacitive biosensor based on vertically paired electrodes for the detection of SARS-CoV-2SARS-CoV-2 검출을 위한 수직 쌍 전극을 기반으로 하는 정전 용량 바이오센서Article Published on 2022-04-152022-09-11 Journal: Biosensors & bioelectronics [Category] COVID19(2023년), SARS, 치료기술, [키워드] 229E anti-SARS-CoV-2 applied Capacitive biosensor Computer simulation Conductive polymer cultures cutoff value diagnosis of COVID-19 different electrode dilution factor Dry etching electrode enhancement etched immunoassay in viral increase in lateral flow immunoassay limit of detection medical diagnosis MERS MERS-CoV nucleoprotein Nucleoprotein (NP) PEDOT:PSS Polymer reactive SARS-CoV SARS-CoV-2 SARS-CoV-2 nucleoprotein sensitivity Vertically paired electrode. viral culture was performed [DOI] 10.1016/j.bios.2022.113975 PMC 바로가기 [Article Type] Article
Hydrophobic Localized Enrichment of Co-reactants to Enhance Electrochemiluminescence of Conjugated Polymers for Detecting SARS-CoV-2 Nucleocapsid ProteinsSARS-CoV-2 뉴클레오캡시드 단백질 검출을 위한 공액 중합체의 전기화학발광을 향상시키기 위한 공반응물의 소수성 국소 농축Article Published on 2022-03-152022-09-11 Journal: Analytical Chemistry [Category] SARS, 치료기술, 치료법, [키워드] antibody Antigen biosensor capture antigen carbon carboxyl complexes Conjugated Detection limit ECL Electrochemiluminescence enrichment hydrophobic inspiration Localized metal ion metal ions platform PNP Polymer propylamine Protein reactants SARS-CoV-2 SARS-CoV-2 nucleocapsid secondary antibody sensitivity [DOI] 10.1021/acs.analchem.1c05407 PMC 바로가기 [Article Type] Article
Plasmonic Detection of SARS-CoV-2 Spike Protein with Polymer-Stabilized Glycosylated Gold Nanorods폴리머 안정화 글리코실화 금 나노로드를 사용한 SARS-CoV-2 스파이크 단백질의 플라즈몬 검출Article Published on 2022-03-152022-09-11 Journal: ACS macro letters [Category] COVID19(2023년), SARS, 치료기술, [키워드] binding capture clinical samples Control experiment correlated correlation COVID-19 COVID-19 pandemic demonstrated detection diagnostic dose-dependent galactosamine glycan glycans glycosylated gold highlight immobilization Infection Particle Patient Polymer reducing response responses against rod SARS-CoV-2 SARS-CoV-2 spike protein selective shown spike Spike protein Surveillance swab samples the SARS-CoV-2 utility [DOI] 10.1021/acsmacrolett.1c00716 PMC 바로가기 [Article Type] Article
Recent advances and applications of polymeric materials in healthcare sector and COVID-19 managementResearch article Published on 2022-02-282022-10-05 Journal: Sensors (Basel, Switzerland) [Category] 치료제, [키워드] antimicrobial Antiviral coronavirus disease COVID-19 COVID-19 outbreak develop functional global public health healthcare help IMPROVE management pandemic Personal protective equipment Plastics Polymer Polymeric materials recent researcher SARS-CoV-2 [DOI] 10.1016/j.matpr.2022.02.472 [Article Type] Research article
Nanoparticle Delivery Platforms for RNAi Therapeutics Targeting COVID-19 Disease in the Respiratory TractReview Published on 2022-02-222022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, [키워드] acute respiratory syndrome administration advance animal model antiviral drugs Antiviral treatment approval carrier caused coronavirus COVID-19 COVID-19 disease delivery disease drug Ensuring FDA food Gene therapy globe glycogen nanoparticles inhalation limitation Lipid nanoparticles Local lung nanomedicine nanoparticle nanoparticle-capsulated drug delivery new treatment strategy organ pandemic of COVID-19 platform Polymer polymer nanoparticles provide respiratory respiratory diseases RNA SARS-CoV-2 SARS-COV-2 infection severe respiratory infections siRNA siRNAs specific tissue specific treatment Spread targeting therapeutic Therapeutics therapy tract treat variety [DOI] 10.3390/ijms23052408 PMC 바로가기 [Article Type] Review