Mutational Hotspot in the SARS-CoV-2 Spike Protein N-Terminal Domain Conferring Immune Escape PotentialSARS-COV-2 스파이크 단백질 N- 말단 도메인 면역 탈출 가능성을 부여하는 돌연변이 핫스팟Article Published on 2021-10-202022-09-01 Journal: Viruses [Category] MERS, SARS, 변종, 진단, 치료기술, [키워드] ACE2 binding adaptive coronavirus Critical database defined Early detection Efficiency effort escape evaluated Evolution of SARS-CoV-2 exhibiting flexibility Frequency Genotype genotypes geographical location global efforts identify Immune escape increase in independent investigated Lineage Local maintain MONITOR Mutation mutational hotspot Mutational hotspots mutations N-terminal domain Neutralizing antibodies neutralizing antibody NTD Phylogenetic phylogenies Phylogeny positioned Potential Protein Receptor-binding domain recruitment residue SARS-CoV-2 evolution SARS-CoV-2 genome SARS-CoV-2 lineage sequence sequences spike spike mutations spike NTD Spike protein Substitution Surveillance the receptor-binding domain the SARS-CoV-2 the Spike Viral viral evolution virulence virus W152 [DOI] 10.3390/v13112114 PMC 바로가기 [Article Type] Article
Estimating the direct Covid-19 disability-adjusted life years impact on the Malta population for the first full year직접 CovID-19 장애 조정 수명 수명 추정 첫해 동안 몰타 인구에 미치는 영향Research Published on 2021-10-092022-09-10 Journal: BMC Public Health [Category] MERS, SARS, 변종, [키워드] Analysis burden Burden of disease calculate calculated Care cause comparison Consensus consequence contributed contributing to coronavirus COVID-19 COVID-19 infection DALY deaths Disability-adjusted life years disease European European burden of disease network Factor Health Hospital admission hospitalisation impacted Infection life Malta morbidity morbidity and mortality network Population health population level positioned required Result Sensitivity analyses Vaccine variants were infected were used without symptoms YLD YLL [DOI] 10.1186/s12889-021-11893-4 PMC 바로가기 [Article Type] Research
Platelets in the perspective of COVID-19; pathophysiology of thrombocytopenia and its implication as prognostic and therapeutic opportunityReview article Published on 2021-10-012022-10-05 Journal: International immunopharmacology [Category] 바이오마커, [키워드] Activation addition appear association clearance Coagulopathy concerning Consensus COVID-19 COVID-19 case COVID-19 patient diagnostic effort IMPROVE induce Infection International Laboratory management mechanisms Novel coronavirus parameter pathophysiology Patient Perspective physician Platelet positioned Prognosis prognostic Prognostic value provide question reduce Research respiratory virus SARS-CoV-2 scrutiny therapeutic therapeutic approaches Therapeutic strategies These cells thrombocytopenia Treatment [DOI] 10.1016/j.intimp.2021.107995 [Article Type] Review article
Genetic counseling student rotations in industry: How COVID-19 magnified the urgency for virtual learning options in diverse training settings업계의 유전 상담 학생 순환: COVID-19가 다양한 교육 환경에서 가상 학습 옵션의 긴급성을 어떻게 확대했는지Article Published on 2021-10-012022-09-11 Journal: Journal of genetic counseling [Category] SARS, 유전자 메커니즘, [키워드] adjust counseling COVID-19 COVID-19 pandemic develop diagnostic Diversity education example expand exposure to FIVE Genetic Genetic counseling genetic counseling rotations Healthcare system highlight imperative Inc. Increasing Laboratory myriad offered participated positioned required training transformation unique urgency variety [DOI] 10.1002/jgc4.1500 PMC 바로가기 [Article Type] Article
The perspective of Canadian health care professionals on abortion service during the COVID-19 pandemicHealth Service Research Published on 2021-09-232022-10-31 Journal: Family practice [Category] Coronavirus, MERS, SARS, [키워드] access Access to health care Canada Care changed conducted Contraception country COVID-19 COVID-19 pandemic cross-sectional survey described Health increasingly indicated induced abortion initial measure medication MOST objective Operating room Other pandemic participant Participants participated Patient Perspective Physicians Podcast positioned Practitioner professional Quantitative question Regulation reported Research restriction Result robust seeking shifting suggested surgical surveys and questionnaires thematic analysis transition care Virtual care [DOI] 10.1093/fampra/cmab083 PMC 바로가기 [Article Type] Health Service Research
Efficacy of Various Facial Protective Equipment for Infection Control in a Healthcare Setting의료 환경에서 감염 제어를위한 다양한 안면 보호 장비의 효능Endemic Infections Published on 2021-09-172022-09-10 Journal: Western Journal of Emergency Medicine [Category] MERS, SARS, 치료제, [키워드] analyzed angle average collected data Contamination Control coronavirus Coronavirus 2019 coughing COVID-19 decrease Diseases distribution droplet droplet transmission droplets Efficacy equipment Evidence Face shield facial Fluorescein head Health healthcare healthcare worker Healthcare workers less lowest mannequin Mask Masks medical masks Pairwise comparison pandemic Particle Particles plastic positioned PPE Protective protective covering reduced repeated repeated measure Result setting tested Transmission transmissions urgency was used wearing [DOI] 10.5811/westjem.2021.3.50516 PMC 바로가기 [Article Type] Endemic Infections
Mental Health Screening in General Practices as a Means for Enhancing Uptake of Digital Mental Health Interventions: Observational Cohort StudyObservational Study Published on 2021-09-162022-10-04 Journal: Journal of Medical Internet Research [Category] SARS, 임상, [키워드] Anxiety assist candidate COVID-19 pandemic Critical Depression depressive Digital digital mental health Enhancing evaluate facilitate General practice general practitioner Generalized Implementing IMPROVE include Intervention less majority medication mental health mental illness Mild moderate objective Patient positioned Practice provide recommendation reported Result Screening Symptom Symptoms symptoms of depression Treatment untreated patient uptake [DOI] 10.2196/28369 PMC 바로가기 [Article Type] Observational Study
Supporting newly graduated medical doctors in managing COVID-19: An evaluation of a Massive Open Online Course in a limited-resource settingObservational Study Published on 2021-09-102022-10-04 Journal: PLoS ONE [Category] 임상, [키워드] aligned benefit collected combating conducted contributing to Course COVID-19 evaluate facilitated Factor framework Future implementation Improvements increase in Indonesian language inhibiting knowledge management massive Medical doctor MOST pandemic Part participant platform positioned Quality question questionnaire reference resources response Result Satisfaction significantly subject Supporting [DOI] 10.1371/journal.pone.0257039 PMC 바로가기 [Article Type] Observational Study
The “Vulnerability” Discourse in Times of Covid-19: Between Abandonment and Protection of Canadian Francophone Older AdultsPublic Health Published on 2021-09-032022-10-31 Journal: Frontiers in Public Health [Category] Coronavirus, MERS, SARS, [키워드] abandonment age ageism Analysis Canada Canadian conducted content contributed Course discourse ENhance finding First wave Francophone media French media Model Older older adult Older adults pandemic positioned protection representation Result silent Stereotype theory time [DOI] 10.3389/fpubh.2021.662231 PMC 바로가기 [Article Type] Public Health
Pericytes: Intrinsic Transportation Engineers of the CNS MicrocirculationPhysiology Published on 2021-08-232022-10-31 Journal: Frontiers in Physiology [Category] COVID-19, [키워드] Activation Alzheimer’s disease blood flow blood-brain barrier Brain capillary network cellular CNS contractile proteins Engineer function functional hyperemia identify identity Immune homeostasis mice Microcirculation neuronal Neurovascular neurovascular coupling oxygen pericyte pericytes positioned progeny regenerative medicine respond stroke subtype Therapeutic strategies [DOI] 10.3389/fphys.2021.719701 PMC 바로가기 [Article Type] Physiology