Induction of Potent and Durable Neutralizing Antibodies Against SARS-CoV-2 Using a Receptor Binding Domain-Based Immunogen수용체 결합 도메인 기반 면역원을 사용한 SARS-CoV-2에 대한 강력하고 내구성 있는 중화 항체 유도Comparative Study Published on 2021-03-112022-09-12 Journal: Frontiers in Immunology [Category] SARS, 진단, [키워드] adjuvant Against animal antibody Antibody avidity Antibody Response Antibody titer Antibody titers B-cell epitope cause COVID-19 disease Effect effective Efficacy examined glycoprotein immune system immunized immunogen IMPROVE induction infectious viruses intraperitoneally mice mortality rate NAb neutralization titer neutralizing antibody novel Betacoronavirus observation period pandemic potent Protective Protein public health systems RBD RBD antigen Receptor binding domain regimen Result Safe SARS-CoV-2 severe pneumonia subunit the RBD Vaccine vaccine candidate zoonosis [DOI] 10.3389/fimmu.2021.637982 PMC 바로가기 [Article Type] Comparative Study
Membrane remodeling by SARS-CoV-2 – double-enveloped viral replicationReview Article Published on 2021-02-222022-10-31 Journal: Faculty Reviews [Category] COVID-19, [키워드] acute respiratory syndrome antiviral drug autophagy caused cleave complex complexes coronavirus Coronaviruses deaths develop ENCODE Genome host cells host membrane human cells induce knowledge membrane MOST non-structural protein NSP Nsp3 nsp4 pandemic pathology polyprotein positive producing promote protease Protein Proteins public health systems raised remodeling processe Replication representing RNA RNA genome SARS-CoV-2 SARS-CoV2 single-stranded structural protein structures subgenomic mRNAs subset translation Vaccines Vesicle viral double-stranded RNA viral genome Viral proteins viral replication virus viruses [DOI] 10.12703/r/10-17 PMC 바로가기 [Article Type] Review Article
Optimizing preventive medicine to bridge the gap between clinical medicine and public health for disease control in China: A lesson from COVID-19중국의 질병 통제를 위해 임상 의학과 공중 보건 사이의 격차를 해소하기 위한 예방 의학 최적화: COVID-19의 교훈Article Published on 2021-02-012022-09-11 Journal: Preventive medicine [Category] SARS, 치료기술, [키워드] China Chinese clinical medicine clinical skills Control system coronavirus disease Coronavirus disease 2019 COVID-19 curative curative medicine disease disease control disease detection Early detection effective Health Health Education highlight Human human resource Human resources limit Outbreaks pandemic Perspective Preventive medicine Public public health public health systems Regulation resource restrict the disease threat Threats unique [DOI] 10.1016/j.ypmed.2020.106324 PMC 바로가기 [Article Type] Article
The Novel Perspectives Opened by ST2 in the Pandemic: A Review of Its Role in the Diagnosis and Prognosis of Patients with Heart Failure and COVID-19Review Published on 2021-01-262022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] Biomarker cardiovascular comorbidity clinical manifestation connection coronavirus disease Course COVID-19 detectable early diagnosis Effects Evidence Evolution failure fibrosis heart heart failure incidence independent Inflammation isoform Local marker Mortality Multiple Myocardial myocardial injury novel Opened outcome pathway Patient patients with COVID-19 Perspective Prognosis prognosis of patient Prognostic factor public health systems review risk stratification role serum severity ST2 suggested suppression systemic inflammation transmembrane [DOI] 10.3390/diagnostics11020175 PMC 바로가기 [Article Type] Review
Healthcare Professional Standards in Pandemic Conditions: The Duty to Obtain Consent to TreatmentSymposium: COVID-19 Published on 2020-11-092022-10-29 Journal: Journal of bioethical inquiry [Category] Coronavirus, MERS, SARS, [키워드] autonomous benefit condition conditions Consent COVID-19 duty Duty of care engage equipment exceptional healthcare Healthcare professional standards Healthcare provider implication information issue knowledge maintain measure Medicines pandemic Patient patients Practitioner professional PROTECT public health Public health response public health systems question raise recruitment required resolved resource risk Standard Treatment United Kingdom [DOI] 10.1007/s11673-020-10048-1 PMC 바로가기 [Article Type] Symposium: COVID-19
COVID-19 Outcome Prediction and Monitoring Solution for Military Hospitals in South Korea: Development and Evaluation of an ApplicationOriginal Paper Published on 2020-11-042022-10-30 Journal: Journal of Medical Internet Research [Category] COVID-19, SARS, [키워드] 95% CI app application average body temperature Care characteristic chills conducted COVID-19 COVID-19 mortality Cox proportional hazard Critical demographic characteristics develop development Diagnosis Dyspnea ENhance feverishness help hospital Hospitalization introduced lethargy Medical resources Military Medicine modeling monitoring objective outcome oxygen pandemic Patient Patient management patient selection Patient symptoms physical Physicians platform prediction Prediction model Primary outcome prognostic model proportional hazards models public health systems ranged Region response Result risk Risk factors social history solution South Spread sustained Symptom System the patient Treatment Usability variable virus were used [DOI] 10.2196/22131 PMC 바로가기 [Article Type] Original Paper
SARS-CoV-2 in the Amazon region: A harbinger of doom for AmerindiansPolicy Platform Published on 2020-10-292022-10-28 Journal: PLoS Neglected Tropical Diseases [Category] COVID-19, MERS, SARS, [키워드] Amazon rainforest consequence coronavirus 2 Coronavirus disease 2019 COVID-19 expand healthcare immunologically pandemic public health systems resource respiratory SARS-CoV-2 South America Spread susceptible the disease the epidemic weakened widespread [DOI] 10.1371/journal.pntd.0008686 PMC 바로가기 [Article Type] Policy Platform
Lessons Learned from Battling COVID-19: The Korean ExperienceCase Report Published on 2020-10-162022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, [키워드] activity Community Contact tracing country COVID-19 COVID-19 pandemic effective Epidemic equity experience First wave Government healthcare implication infected patients Korean Korean response strategies lesson Lessons learned management pandemic Personal protective equipment PPE practitioners public health public health systems responders second wave South Korea Treatment unique urgency valuable resource virus [DOI] 10.3390/ijerph17207548 PMC 바로가기 [Article Type] Case Report
SARS-CoV-2 RapidPlex: A Graphene-Based Multiplexed Telemedicine Platform for Rapid and Low-Cost COVID-19 Diagnosis and MonitoringResearch article Published on 2020-10-052022-10-05 Journal: Matter [Category] 바이오마커, 치료기술, [키워드] antibodies applicability Asymptomatic individuals Blood C-reactive protein Community COVID-19 COVID-19 infection COVID-19 pandemic Critical detect diagnosis and monitoring evaluated IgM and IgG Infection Inflammatory biomarker MAP6: Development monitoring nucleocapsid protein pilot study platform presymptomatic public health systems Rapid Saliva SARS-CoV-2 selective Telemedicine the SARS-CoV-2 Viral antigen widespread [DOI] 10.1016/j.matt.2020.09.027 [Article Type] Research article
Repurposing existing drugs for COVID-19: an endocrinology perspectiveCorrespondence Published on 2020-09-292022-10-28 Journal: BMC Endocrine Disorders [Category] COVID-19, SARS, [키워드] absence ACE inhibitor ACE2 affected Ageusia aging androgen angiotensin receptor blocker angiotensin-converting enzyme-2 Anosmia Anti-androgen ARB arthralgia assessment candidate caused Clinical effect clinical testing clinical trial coronavirus 2 correlated COVID-19 COVID-19 patient death description Dexamethasone diabetes drug drug treatment effective therapy Efficacy elicited Endocrine Evidence familiarity fatigue Fever Glucocorticoids heterogeneous Hospitalization hypertension include Infection inherent inhibitor lack less mechanical ventilation methodological Mild-to-moderate myalgia N-acetyl cysteine NAC obesity Other outcome pandemic patients Perspective public health systems RAAS reduce mortality reduction in repurposing Research researcher respiratory risk Safe safety profile SARS-CoV-2 severe COVID-19 severely ill patient Symptom target therapeutic options TMPRSS2 transmembrane serine protease while with COVID-19 worse prognosis [DOI] 10.1186/s12902-020-00626-0 PMC 바로가기 [Article Type] Correspondence