BNT162b2 coronavirus disease-2019 vaccination accelerated rheumatoid arthritis disease activity in chronic eosinophilic pneumonia: A case reportArticle Published on 2022-09-302022-11-15 Journal: Medicine [Category] 진단, [키워드] accelerated adverse events Affect Anti-inflammatory antibody BNT162b2 Case report Cell coronavirus COVID-19 COVID-19 vaccination COVID-19 vaccine diagnosed Diagnosis Disease activity eosinophil Eosinophilic had no immune reactions Immunological response Inflammation initial joint laboratory examination peptide Pneumonia pulse reaction receiving reflected respiratory symptom response rheumatoid arthritis steroid treatment suggested Symptom Symptoms T cell T helper therapy vaccination worsened [DOI] 10.1097/MD.0000000000030806 PMC 바로가기
Differential Severe Acute Respiratory Syndrome Coronavirus 2 Antibody Profiles After Allergic Reactions to Messenger RNA Coronavirus Disease 2019 VaccineArticle Published on 2022-09-282022-11-15 Journal: The Journal of Infectious Diseases [Category] SARS, 진단, [키워드] acute respiratory syndrome allergic allergic reaction anaphylaxis antibody antigenic target Control controls coronavirus coronavirus 2 coronavirus disease COVID-19 exhibiting full-length functional humoral Humoral immunity hypersensitivity IgG1 Immunoglobulin individual messenger Messenger RNA Moderna mounted mRNA mRNA COVID-19 vaccine occur Patient Pfizer produced profile reaction receptor recipients reduction in respiratory RNA SARS-CoV-2 significantly lower Symptom systems serology vaccination vaccination. Vaccine [DOI] 10.1093/infdis/jiac107 PMC 바로가기
Reaction of SARS-CoV-2 antibodies with other pathogens, vaccines, and food antigensArticle Published on 2022-09-232022-11-15 Journal: Frontiers in Immunology [Category] SARS, 진단, [키워드] antibodies antibody Antigen antigens autoantigen B cell Bacteria Bacterial BCG Blood casein Combination COVID-19 cross-protection cross-react cross-reactive antibody cross-reactivity DTaP elicit elicited experiment food antigens herpesviruses homology human tissues immune immune response immune system Immunity investigated memory T molecular molecular mimicry monoclonal monoclonal antibody pathogen Pathogens peptide polyclonal antibody Proteins reaction reactivity SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 spike protein shown similarity the SARS-CoV-2 virus Vaccine vaccine antigen Vaccines Vaccines. Viral antigen viruses [DOI] 10.3389/fimmu.2022.1003094 PMC 바로가기
Label free detection of SARS CoV-2 Receptor Binding Domain (RBD) protein by fabrication of gold nanorods deposited on electrochemical immunosensor (GDEI)전기화학적 면역센서(GDEI)에 증착된 금 나노막대를 제작하여 SARS CoV-2 수용체 결합 도메인(RBD) 단백질의 무표지 검출Article Published on 2022-09-152022-09-11 Journal: Biosensors & bioelectronics [Category] COVID19(2023년), SARS, 치료기술, [키워드] AFM antibody binding Blot chain Chain Reaction characterized cloned collected coronavirus disease Coronavirus disease 2019 COVID-19 Cross reactivity cyclic Detection limit DPV dynamic early diagnosis Efficiency electrochemical electron electron carrier Electrophoresis ELISA enzyme enzyme-linked immunosorbent assay expressed fabrication flight fluorine followed by force FTO gel electrophoresis gold Gold nanorods house immobilization Infectious disease kDa lAbel Laser LIGHT MERS middle Middle East Middle East respiratory syndrome molecular weight nasopharyngeal sample Outbreaks output Oxide pandemic polyacrylamide Population Protein RBD RBD antigen RBD gene reaction Receptor binding domain respiratory reverse transcription Reverse transcription-polymerase chain reaction RT-PCR SARS CoV SARS CoV-2 SDS-PAGE shown Spectroscopy spike Spike protein spike protein. stability TEM tested the patient Tin Tin Oxide transmission electron microscopy viral transport media VTM was determined western blot [DOI] 10.1016/j.bios.2022.114406 PMC 바로가기 [Article Type] Article
SARS-CoV-2 vaccination in patients with multiple sclerosis in Germany and the United Kingdom: Gender-specific results from a longitudinal observational studyArticle Published on 2022-09-022022-10-06 Journal: Lancet Reg Health Eur [Category] 진단, [키워드] Adverse adverse events analysed AZD1222 Biogen Bristol Clinical data courses COVID-19 Deterioration effective fatigue Frequency Gender Germany headache Health impairment injection long-lasting longitudinal men Merck Serono Multiple multiple sclerosis Mylan Novartis occurred offer opposite Pain participated Patient reaction real-world data registry reported resulting Roche Sanofi SARS-CoV-2 SARS-CoV-2 vaccination SARS-CoV-2 vaccine sclerosis severe COVID-19 disease Society Sociodemographic stratified Symptoms Tolerability United Kingdom vaccination Vaccination reaction Vaccination reaction. Vaccine women worsened [DOI] 10.1016/j.lanepe.2022.100502 PMC 바로가기 [Article Type] Article
COVID-19 vaccine type-dependent differences in immunogenicity and inflammatory response: BNT162b2 and ChAdOx1 nCoV-19Article Published on 2022-09-022022-11-15 Journal: Frontiers in Immunology [Category] 진단, [키워드] adverse event adverse events anti-S IgG antibody association blood sample BNT162b2 ChAdOx1 nCoV-19 coronavirus disease COVID-19 COVID-19 vaccine cytokine dose elevated enrolled evaluated Fever GRADE healthy humoral immune responses IgG IL-1β IL-6 immunogenicity Inflammatory Inflammatory responses neutralizing antibody responses Neutralizing antibody titer of BNT162b2 opposite participant positively correlated Proinflammatory cytokine reaction reactogenicity recipient recipients response responses resulting second dose significantly systemic systemic adverse event the median vaccination Vaccine vaccine platform vaccine-induced immune response vaccine. Vaccines [DOI] 10.3389/fimmu.2022.975363 PMC 바로가기
Rapid and accurate identification of SARS-CoV-2 Omicron variants using droplet digital PCR (RT-ddPCR)Droplet Digital PCR(RT-ddPCR)을 사용한 SARS-CoV-2 Omicron 변이체의 빠르고 정확한 식별Article Published on 2022-09-012022-09-11 Journal: Journal of Clinical Virology [Category] COVID19(2023년), SARS, 변종, 치료기술, 치료제, [키워드] Allelic discrimination amino acids B.1.1.529 B.1.1.529. Clinical treatment clinician Concentration confounding factor Delta described develop digital PCR Efficacy Frequency genome sequence Genome sequences genotyping identify Laboratory medium Mutation mutations NGS omicron Omicron variants positive Prevalence primer probe sequences problem professionals Protein public health Rapid reaction Receptor binding domain respiratory viruses RNA robust S-gene SARS-CoV-2 SARS-CoV-2 spike protein SARS-CoV-2 variants Sensitivity and specificity shifting specimen spike Spike protein state substantial reduction substantial reductions susceptibility tested the SARS-CoV-2 therapy Transmission Transport transport medium Vaccine vaccine efficacy variant variants Variation Washington [DOI] 10.1016/j.jcv.2022.105218 PMC 바로가기 [Article Type] Article
Repeat subcutaneous administration of casirivimab and imdevimab in adults is well-tolerated and prevents the occurrence of COVID-19Randomized Controlled Trial Published on 2022-09-012022-10-04 Journal: International Journal of Infectious Diseases [Category] COVID19(2023년), SARS, 임상, 진단, [키워드] administration adverse event antibody Casirivimab clinically conducted COVID-19 death defined demonstrated development dose doses double-blind Efficacy end point evaluate evaluated exploratory hypersensitivity reaction Imdevimab incidence of COVID-19 laboratory-confirmed monoclonal antibody occurred Occurrence occurrence of COVID-19 Odds ratio participant Placebo placebo-controlled trial Prevent proportion Randomized reaction reduction in Repeat reported risk reduction SARS-CoV-2 SARS-CoV-2. Seroconversion substantial risk Tolerability treatment period treatment-emergent adverse event uninfected volunteers [DOI] 10.1016/j.ijid.2022.06.045 PMC 바로가기 [Article Type] Randomized Controlled Trial
Detection of COVID-19 using deep learning techniques and classification methodsResearch article Published on 2022-09-012022-10-05 Journal: Information Processing & Management [Category] 진단, 치료기술, [키워드] Accuracy addition AUC value auxiliary can be used chain classification COVID-19 COVID-19 disease COVID-19 patient criteria database decision deep learning detection Diagnosis diagnosis of COVID-19 education evaluated examined feature forest Naive Baye PCR radiologist reaction reduce Resnet ROC Curve Spread Support support vector machine SVM the disease the patient Transmission tree was obtained [DOI] 10.1016/j.ipm.2022.103025 [Article Type] Research article
Evolving strategy for an evolving virus: Development of real-time PCR assays for detecting all SARS-CoV-2 variants of concern진화하는 바이러스에 대한 진화하는 전략: 우려되는 모든 SARS-CoV-2 변이체를 검출하기 위한 실시간 PCR 분석법 개발Article Published on 2022-09-012022-09-11 Journal: Journal of virological methods [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, 치료제, [키워드] Alpha Amino acid amino acid change amino acid changes approach B.1.1.7 Beta Canada characterized clinical sensitivity clinical specificity complementary COVID-19 Critical cross-reactivity Delta detect development discriminatory mutation E gene E484K FIVE Gamma Genome sequencing implementation K417N L452R less limit of detection Lineage molecular MONITOR N501Y Negative predictive value nucleotide omicron Omicron variants P681 Pathogens PCR PCR assays positive Positive predictive value positive predictive values positive sample predictive values reaction real-time PCR assay real-time reverse transcriptase real-time RT-PCR replacement respiratory respiratory pathogen responsible reverse transcriptase rRT-PCR SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genome sequencing SARS-CoV-2 variant SARS-CoV-2 variants sensitivity Single nucleotide polymorphism single nucleotide polymorphisms specificity Spike protein subset Surveillance target the SARS-CoV-2 Variability variant variants variants of concern variants of concern. VoC VOCs while wild-type Δ69-70 [DOI] 10.1016/j.jviromet.2022.114553 PMC 바로가기 [Article Type] Article