Alveolar Regeneration in COVID-19 Patients: A Network PerspectiveCOVID-19 환자의 폐포 재생: 네트워크 관점Review Published on 2021-10-192022-09-10 Journal: International Journal of Molecular Sciences [Category] MERS, SARS, 유전자 메커니즘, 진단, [키워드] alteration alveolar alveolar fibrosis alveolar regeneration biochemical coronavirus disease Coronavirus disease 2019 COVID-19 fibrosis Host host cell host immune system host responses Injury lead lung collapse lung damage network network biology nucleic acid organism patients Protective regeneration Replication SARS-CoV-2 SARS-CoV-2 viral infection signaling pathway triggering Viral viral infection viral nucleic acid [DOI] 10.3390/ijms222011279 PMC 바로가기 [Article Type] Review
Impaired function and delayed regeneration of dendritic cells in COVID-19코로나19에서 손상된 수지상 세포의 기능 장애 및 재생 지연Clinical Trial Published on 2021-10-062022-09-10 Journal: PLoS Pathogens [Category] MERS, SARS, 바이오마커, 임상, [키워드] accompanied activated acute illness acute phase adaptive Adaptive immune response adaptive immune responses alteration analyzed antibody antibody-secreting cells antiviral immunity Blood CD14 CD14+ cell CD14+ cells CD163 CD4 CD86 Cell cells circulating classical monocyte classical monocytes Clinical management consequence contribute correlated COVID-19 COVID-19 patient COVID-19 patients COVID-19 severity DCs dendritic cell dendritic cells Depletion disease disease severity downregulation dysregulated dysregulated innate immune response expansion follicular Frequency functional healthy controls helper cells HLADR hospitalized COVID-19 patient Host immune response identify immune responses immunopathology Impaired impairment Increased Inflammatory response Inflammatory responses inhibitory innate immune response long-lasting manifestation Mild modulation monocyte monocyte subsets Monocytes naïve Patient PD-L1 persistent recognize reduced reduction regeneration SARS-COV-2 infection Secondary infection secondary infections severe disease stimulate subpopulation subset susceptibility systemic inflammation T cell T cells T follicular helper cells the disease therapy these cell These cells Trigger upregulation Viral viral infection viral infections [DOI] 10.1371/journal.ppat.1009742 PMC 바로가기 [Article Type] Clinical Trial
Greek gods and the double-edged sword of liver regeneration그리스 신들과 간 재생의 양날의 검Editorial Published on 2021-10-012022-09-11 Journal: Biomedical journal [Category] SARS, 변종, [키워드] approach Arthroplasty bone Bone marrow Bone marrow mesenchymal stem cell caspase complex copy number copy number variant Copy number variants Definition dental implants dependence fibrosis flipped classroom G protein-coupled receptor Geography GPCR healthcare hepatitis C hepatitis C virus hospital investigated journal liver Liver damage Liver fibrosis liver tissue Long long non-coding RNA mesenchymal stem cell mutant polymorphism regeneration SARS-CoV2 stem cell stem cells Taiwan Telemedicine Total Total knee arthroplasty [DOI] 10.1016/j.bj.2021.10.010 PMC 바로가기 [Article Type] Editorial
Muscle Regeneration and RNA: New Perspectives for Ancient MoleculesReview Published on 2021-09-232022-10-31 Journal: Cells [Category] Coronavirus, SARS, [키워드] applied approaches biochemical Biomarker cardiac regeneration coding Diseases drug Effectiveness example homeostasis Hypothesis in vitro intrinsic involved less lncRNA mechanism miRNA molecule mRNA-based vaccines muscle ncRNA ncRNAs New non-coding RNA noncoding RNAs (ncRNAs) pathology regeneration Regulation RNA RNA therapeutics SARS-CoV-2 single-stranded siRNA skeletal muscle regeneration suggested supported target therapeutic tissue Treatment unique [DOI] 10.3390/cells10102512 PMC 바로가기 [Article Type] Review
The Microvillar and Solitary Chemosensory Cells as the Novel Targets of Infection of SARS-CoV-2 in Syrian Golden HamstersArticle Published on 2021-08-202022-10-28 Journal: Viruses [Category] COVID-19, MERS, SARS, [키워드] activated acute respiratory syndrome angiotensin-converting enzyme 2 apoptotic cell basal cells Cell cells cellular components change chemosensory contribute coronavirus coronavirus disease damaged determine epithelia expression hamster Infection infiltration inflammatory cells influence Loss of Smell microenvironment microvillar cell nasal novel olfactory Olfactory epithelium olfactory function Olfactory system organ pathologic pathological change receptor protein reduced regeneration SARS-CoV-2 second solitary chemosensory cell Structure Symptoms Syrian golden hamster Syrian Golden hamsters target these symptoms viral infection vomeronasal were used [DOI] 10.3390/v13081653 PMC 바로가기 [Article Type] Article
The Role of Macrophages During Mammalian Tissue Remodeling and Regeneration Under Infectious and Non-Infectious ConditionsImmunology Published on 2021-07-142022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, SARS, [키워드] cell death characterized condition conditions danger signal functional humans immune cells implicated IMPROVE Infection infectious conditions Injury lesion lung damage Lungs Macrophage response macrophages mammal mammals non-infected non-infectious non-infectious conditions organ organs Pathogenic microorganisms pathology patients recruitment regeneration regenerative remodeling repair respond responsible role SARS-CoV-2 scar Skeletal muscle therapy tissue tissue damage tissue repair Tuberculosis with COVID-19 [DOI] 10.3389/fimmu.2021.707856 PMC 바로가기 [Article Type] Immunology
Human Platelet Lysate for Good Manufacturing Practice-Compliant Cell ProductionReview Published on 2021-05-132023-08-30 Journal: International Journal of Molecular Sciences [Category] E형 간염, [키워드] Cell therapy good manufacturing practice (GMP) human platelet lysate (HPL) platelet concentrates regeneration regenerative medicine [DOI] 10.3390/ijms22105178 PMC 바로가기 [Article Type] Review
The Tissue Renin-Angiotensin System and Its Role in the Pathogenesis of Major Human Diseases: Quo Vadis?Review Published on 2021-03-152022-10-31 Journal: Cells [Category] COVID-19, [키워드] AGTR1 angiotensin Angiotensin II Anti-inflammatory Autoimmune disease cardiovascular COVID-19 COVID-19 pandemic disease Effect highlight Human human diseases Inflammation Inflammatory interact intervertebral disc involved Major neuropathic Numerous Pain pathologic pathway Pathways Perspective positive pro-inflammatory progression Protective RAS receptor regeneration Regulatory renin-angiotensin renin-angiotensin system reported role SARS-CoV 2 senescence System therapeutic strategy this system tissue Treatment vulvodynia [DOI] 10.3390/cells10030650 PMC 바로가기 [Article Type] Review
Ex uno, plures –From One Tissue to Many Cells: A Review of Single-Cell Transcriptomics in Cardiovascular BiologyReview Published on 2021-02-192023-06-12 Journal: International Journal of Molecular Sciences [Category] MERS, [키워드] cardiac development differentiation heart Injury regeneration scRNAseq single-cell [DOI] 10.3390/ijms22042071 PMC 바로가기 [Article Type] Review
Nanoconjugates-Based Stem Cell Therapy for the Management of COVID-19Review Published on 2021-02-012023-06-19 Journal: Stem cell reviews and reports [Category] MERS, SARS, [키워드] Corona virus Inflammation Lung injury Pre-clinical trials regeneration [DOI] 10.1007/s12015-020-10079-6 PMC 바로가기 [Article Type] Review