Ribonucleic acid – Page 3 – Communicable Diseases Research

Identification of SARS-CoV-2 on the ocular surface in a cohort of COVID-19 patients from Brazil

브라질 COVID-19 환자 코호트의 안구 표면에서 SARS-CoV-2 식별

Original Research

Published on 2021-07-192022-09-11
Journal: Experimental Biology and Medicine [Category] SARS, 진단, 치료기술, 치료제,

Viral transmission and evolution dynamics of SARS-CoV-2 in shipboard quarantine

선박 보드 검역에서 SARS-COV-2의 바이러스 전염 및 진화 역학

Research

Published on 2021-07-012022-09-10
Journal: Bulletin of the World Health Organization [Category] 변종,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 America analysed Analysis collected computational tool computational tools contributed coronavirus Cruise ship database de novo diamond Evolution finding FIVE Genetic genetic linkage Increased individual Influenza initiative isolates Japan linkage Mutation natural selection objective outbreak phylogenetics Positive selection Princess progeny quarantine Recombination respiratory Ribonucleic acid RNA RNA recombination SARS-CoV-2 SARS-CoV-2 genome sequence SARS-CoV-2 genome sequences sequenced severe acute respiratory syndrome Coronavirus single person Spread statistically significant subgroups tested the United State Transmission United States variant Viral viral mutation virus
[DOI] 10.2471/BLT.20.255752 PMC 바로가기 [Article Type] Research

Acute kidney injury in COVID-19: are kidneys the target or just collateral damage? A comprehensive assessment of viral RNA and AKI rate in patients with COVID-19

COVID-19의 급성 신장 손상: 신장이 표적입니까 아니면 부수적인 손상입니까? COVID-19 환자의 바이러스 RNA 및 AKI 비율에 대한 포괄적인 평가

Review

Published on 2021-07-012022-09-11
Journal: Current opinion in urology [Category] SARS, 치료기술, 치료제,

[키워드] Acute kidney injury acute respiratory syndrome AKI available data causative agent Chronic kidney disease CKD confidence interval coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 correlated COVID-19 COVID-19 severity Cytokine storm detect Effect Frequency identify in urine kidney Kidney disease Kidney function Kidney injury moment MOST mRNA Odds ratio Patient patients with COVID-19 Prospective trial recent Research Ribonucleic acid RNA SARS-CoV-2 Severe acute respiratory syndrome Severe acute respiratory syndrome-related coronavirus severity the disease the patient Topic undetectable Urine viral ribonucleic acid Viral RNA
[DOI] 10.1097/MOU.0000000000000901 PMC 바로가기 [Article Type] Review

Rapid and Sensitive Detection of Severe Acute Respiratory Syndrome Coronavirus 2 in Label-Free Manner Using Micromechanical Sensors

미세 기계 센서를 사용하여 라벨이 없는 방식으로 중증 급성 호흡기 증후군 코로나바이러스 2의 신속하고 민감한 감지

Communication

Published on 2021-06-292022-09-10
Journal: Sensors (Basel, Switzerland) [Category] MERS, SARS, 변종, 치료기술, 치료제,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 capture caused Chain Reaction complementary Complementary DNA coronavirus coronavirus 2 COVID-19 COVID-19 pandemic detection determine diagnostic diagnostic methods DNA DNA hybridization dynamic mode effort Frequency Genomic analysis identify infected patients Laboratory microcantilever sensor offer oligonucleotide probe pandemic performed probe Rapid resonance frequency respiratory Reverse transcription-polymerase chain reaction Ribonucleic acid RNA RT-PCR SARS-CoV-2 SARS-CoV-2 detection sensitive sensor severe acute respiratory syndrome Coronavirus shift single-stranded variant Viral viral ribonucleic acid
[DOI] 10.3390/s21134439 PMC 바로가기 [Article Type] Communication

Correlation of SARS-CoV-2 RNA in wastewater with COVID-19 disease burden in sewersheds

폐수에서 SARS-CoV-2 RNA와 하수구의 COVID-19 질병 부담의 상관관계

Article

Published on 2021-06-252022-09-11
Journal: The Science of the total environment [Category] SARS, 치료기술,

[키워드] 1.26 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 assist cause Characteristics Community conducted coronavirus coronavirus disease Correlation analysis COVID-19 COVID-19 case COVID-19 cases detectable disease Disease burden Epidemiology Evidence evidence of feces frequencies increase in individual infiltration inflow Interceptor outbreak positively correlated Public health response Public health responses Ribonucleic acid RNA SAR-CoV-2 SARS-CoV-2 SARS-CoV-2 RNA severe acute respiratory syndrome Coronavirus sewershed urban Utah utility viral ribonucleic acid virus wastewater wastewater epidemiology with COVID-19
[DOI] 10.1016/j.scitotenv.2021.145790 PMC 바로가기 [Article Type] Article

Detection and viral RNA shedding of SARS-CoV-2 in respiratory specimens relative to symptom onset among COVID-19 patients in Bavaria, Germany

독일 바이에른의 COVID-19 환자의 증상 발병과 관련하여 호흡기 표본에서 SARS-CoV-2의 검출 및 바이러스 RNA 방출

Article

Published on 2021-06-232022-09-11
Journal: Epidemiology and Infection [Category] SARS, 치료기술,

[키워드] 95% CI 95% confidence interval acute respiratory syndrome Chain Reaction clearance comparable coronavirus coronavirus disease COVID-19 COVID-19 cases COVID-19 patient Ct-value Ct-values cycle threshold detection diagnostic diagnostic sensitivity estimate Germany individual Kaplan-Meier plot Kaplan-Meier plots lowest Patient patients presymptomatic transmission Probability proportion remained reported respiratory specimen reverse transcriptase reverse transcriptase-polymerase chain reaction Ribonucleic acid RNA RT-PCR sampling SARS-CoV-2 SARS-CoV-2 detection scatterplot sensitivity Severe acute respiratory syndrome severe acute respiratory syndrome-coronavirus-2 specimen subset symptom onset symptomatic tested the timing Viral load viral ribonucleic acid Viral RNA Viral RNA shedding was used were used
[DOI] 10.1017/S0950268821001345 PMC 바로가기 [Article Type] Article

Assessing the efficacy and safety of hydroxychloroquine as outpatient treatment of COVID-19: a randomized controlled trial

COVID-19의 외래 환자 치료로서 하이드록시클로로퀸의 효능 및 안전성 평가: 무작위 대조 시험

Randomized Controlled Trial

Published on 2021-06-182022-09-11
Journal: CMAJ open [Category] SARS, 임상, 치료제,

[키워드] 95% confidence interval Assessing assigned Chain Reaction Community Composite conducted Contact contact with Controlled trial COVID-19 COVID-19 pandemic death determine determined by did not reduce direct contact disposition effect of treatment Efficacy and safety eligible enrolment Evidence expected First wave Follow-up hazard ratio Hospitalization hospitalizations hospitalized patient hospitalized patients Hydroxychloroquine hydroxychloroquine group hydroxychloroquine treatment identification individual Invasive mechanical ventilation matching placebo mechanical ventilation Mortality outcome outcomes Outpatient outpatients participant Participants patients PCR test Placebo placebo group polymerase chain polymerase chain reaction positive RT-PCR Prevent prevented Primary outcome priority raised Randomized controlled trial Randomly reduced resulting reverse transcription reverse transcription polymerase chain reaction Ribonucleic acid RT-PCR Safety SARS-COV-2 infection secondary Secondary outcomes Serious Adverse Event Serious Adverse Events severe COVID-19 study drug survived symptom duration symptom onset the placebo group therapy Treatment Trial viral ribonucleic acid with COVID-19
[DOI] 10.9778/cmajo.20210069 PMC 바로가기 [Article Type] Randomized Controlled Trial

Design and Numerical Analysis of a Graphene-Coated SPR Biosensor for Rapid Detection of the Novel Coronavirus

신종 코로나바이러스의 신속한 검출을 위한 그래핀 코팅 SPR 바이오센서의 설계 및 수치 분석

Article

Published on 2021-05-172022-09-10
Journal: Sensors (Basel, Switzerland) [Category] SARS, 치료기술,

[키워드] Accuracy added addition Algorithm Analysis analyte analyzed Anti-spike biosensor changed checked coated Concentration coronavirus COVID-19 COVID-19 virus detection Detection sensitivity Diagnosis excitation expected False positive figure Frequency Graphene IgG IgM Interaction investigated Ligand mAbs molecular detection monoclonal antibodies monoclonal antibody novel Novel coronavirus offer pandemic probe Protein provide quality factor Rapid rapid detection RBD Receptor-binding domain reduce refractive index Ribonucleic acid RNA SARS-CoV-2 sensitivity sensor spike receptor-binding domain SPR Spread surface plasmon surface plasmon resonance Total Internal Reflection transfer two-dimensional Viral Viral RNA virus Virus spike were used
[DOI] 10.3390/s21103491 PMC 바로가기 [Article Type] Article

Pharmacokinetic, Pharmacodynamic, and Drug-Interaction Profile of Remdesivir, a SARS-CoV-2 Replication Inhibitor

SARS-CoV-2 복제 억제제인 렘데시비르의 약동학, 약력학 및 약물 상호작용 프로필

Review

Published on 2021-05-012022-09-11
Journal: Clinical pharmacokinetics [Category] SARS, 치료기술, 치료제,

[키워드] accumulate Activation acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 administration Analysis approval approvals Cell children Clinical data clinical dosing clinically Concentration coronavirus coronavirus disease Coronavirus disease 2019 country COVID-19 dose dose regimen doses drug-drug interaction Drug-drug interactions eliminated enzyme followed by GS-441524 healthy healthy volunteers Hospitalized in vitro inducer infected with COVID-19 inhibitor inhibitors intravenous Intravenous administration linear Loading dose maintenance dose metabolite mononuclear cells multiple dose multiple doses nucleoside once daily parenteral route Participants Patient patients with COVID-19 Peripheral blood Peripheral blood mononuclear cells Pharmacodynamic pharmacokinetic pharmacokinetics Phase I plasma polymerase predicted profile rationale RDV regimen Remdesivir Replication Result Ribonucleic acid SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe coronavirus disease therapeutic Treatment treatment of COVID-19 triphosphate Veklury was selected
[DOI] 10.1007/s40262-021-00984-5 PMC 바로가기 [Article Type] Review

SARS-CoV-2 Leakage From the Gas Outlet Port During Extracorporeal Membrane Oxygenation for COVID-19

COVID-19에 대한 체외막 산소화 중 가스 배출구에서 SARS-CoV-2 누출

Observational Study

Published on 2021-05-012022-09-11
Journal: ASAIO journal (American Society for Artificial Int [Category] SARS, 임상, 치료기술,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Blood Care Chain Reaction coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patients COVID-19 pneumonia Critical Critically ill critically ill COVID-19 patients develop ECMO Extracorporeal extracorporeal membrane oxygenation FIVE Gas Outlet infected with COVID-19 infection control involved leak leakage liberation medical staff membrane occur outlet oxygenator Patient patients plasma Pneumonia polymerase chain polymerase chain reaction Polypropylene Quantitative Respiratory failure reverse transcription Ribonucleic acid RNA SARS-CoV-2 SARS-CoV-2 RNA serum severe acute respiratory syndrome Coronavirus silicone Support venovenous extracorporeal membrane oxygenation VV-ECMO was measured were used
[DOI] 10.1097/MAT.0000000000001402 PMC 바로가기 [Article Type] Observational Study