50-gene risk profiles in peripheral blood predict COVID-19 outcomes: A retrospective, multicenter cohort study말초 혈액의 50개 유전자 위험 프로필이 COVID-19 결과를 예측합니다: 후향적, 다기관 코호트 연구Multicenter Study Published on 2021-07-012022-09-11 Journal: EBioMedicine [Category] MERS, 바이오마커, 유전자 메커니즘, [키워드] 50-gene risk profiles Action Adaptive immune response analyzed applied B cells Blood CD4 CD8 Cell cellular change Chicago Cohort cohorts college COVID-19 Cutoff dendritic cells Dendritic Cells and Neutrophils Diseases expressing Features fibrosis foundation Gene Expression heart ICU ICU admission identify idiopathic Idiopathic pulmonary fibrosis IgG immune immune responses in-hospital mortality intensive care intensive care unit Interstitial lung disease investigated IPF London Lung disease Lymphocytes mechanical ventilation Mild Monocytes Mortality multicenter cohort study Neutrophils NHLBI outcomes overlap Peripheral blood plasmablasts predict predicted Predictive producing profile profiles pulmonary pulmonary fibrosis retrospective risk RNA-sequencing scientist Scoring South supported T cells T lymphocytes transcript level transcriptomic university validation was used were used [DOI] 10.1016/j.ebiom.2021.103439 PMC 바로가기 [Article Type] Multicenter Study
A randomized and comparative study to assess safety and efficacy of supplemental treatment of a herbal formulation – Aayudh Advance comprising essential oils in patients with corona virus 2019 (COVID-19)Research article Published on 2021-06-012022-10-05 Journal: Contemporary Clinical Trials Communications [Category] 치료법, [키워드] Aayudh advance advance Adverse Adverse drug reaction Arm ARMS assigned biochemical body temperature breath clinical Clinical improvement Clinical sign Control Corona Covariate adaptive randomization COVID-19 COVID-19 negative COVID-19 patients CRP Ct value diagnosed discharge drug interaction E gene E-gene effective Efficacy enrolled exclusion criteria Herbal hospital in viral Inclusion indicated Mild NLR objective Patient protocol Randomized reaction reduction reported Result RT-PCR Safe Scoring Serum ferritin significant increase Standard Standard of care (SOC) statistically significant reduction Symptom symptomatic symptomatic patient Test the patient Total Treatment treatment group Viral load virus were recorded withdrawn [DOI] 10.1016/j.conctc.2021.100755 [Article Type] Research article
Resuscitative Effect of Centhaquine (Lyfaquin ®) in Hypovolemic Shock Patients: A Randomized, Multicentric, Controlled Trial저혈량성 쇼크 환자에서 Centhaquine(Lyfaquin®)의 소생 효과: 무작위, 다중심, 대조 시험Clinical Trial Published on 2021-06-012022-09-11 Journal: Advances in therapy [Category] SARS, 비임상, 임상, [키워드] 1:1 added adverse event all-cause mortality animal model animal models ARDS base deficit baseline Blood both groups breath Centhaquine Clinical outcome comparable conducted control group Controlled demographics determine diastolic distress Effect effective Efficacy female patient greater Haemoglobin Haemorrhage healthy Hypovolemia hypovolemic Hypovolemic Shock ICU IMPROVE improvement Improvements in both group in both groups increase in Lactate less major surgery male MODS multicentre multiple organ dysfunction multiple organ dysfunction syndrome normal saline observation period organ dysfunction syndrome Patient Randomized respiratory distress Respiratory distress syndrome Resuscitation Resuscitative agent Scoring Shock Standard of care Support syndrome System the patient Tolerability Vasopressor vasopressors ventilator volunteers was recorded [DOI] 10.1007/s12325-021-01760-4 PMC 바로가기 [Article Type] Clinical Trial
Model of End-Stage Liver Disease (MELD) Score as a Predictor of In-Hospital Mortality in Patients with COVID-19: A Novel Approach to a Classic Scoring SystemInternal Medicine Published on 2021-05-222022-10-31 Journal: Cureus [Category] COVID-19, [키워드] age Asthma both group chronic heart failure Chronic kidney disease CKD classic clinical Cohort cohort study COVID-19 COVID-19 positive patient Dementia Diabetes Mellitus diagnosed with COVID-19 discharge evaluated greater group hospital Hospitalized hypertension ICU in-hospital mortality Infection Inflammation intensive care Limited Liver disease liver dysfunction LOS meld Model Mortality no significant difference novel Older outcome Patient predictor Prognosis Result risk score Scoring significantly higher stratified survival System viral infection with COVID-19 women [DOI] 10.7759/cureus.15179 PMC 바로가기 [Article Type] Internal Medicine
Risk Factors and a Scoring System to Predict ARDS in Patients with COVID-19 Pneumonia in Korea: A Multicenter Cohort Study한국의 COVID-19 폐렴 환자에서 ARDS를 예측하는 위험 요인 및 점수 시스템: 다기관 코호트 연구Multicenter Study Published on 2021-04-092022-09-10 Journal: Disease Markers [Category] MERS, SARS, 바이오마커, [키워드] 95% CI acute respiratory distress acute respiratory distress syndrome age ARDS C-reactive protein CAPS characteristic Characteristics chest X-ray collected coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pneumonia determine diagnosed with COVID-19 enrolled epidemiological Factor FIVE form Health Organization infiltration investigated Logistic regression analysis neutrophil outcome Patient patients with COVID-19 Pneumonia predict prediction Predictive predictor progression provided receiver receiver operating characteristic report respiratory distress ROC score score cutoff Scoring sensitivity specificity syndrome System university hospital was performed with COVID-19 World Health Organization [DOI] 10.1155/2021/8821697 PMC 바로가기 [Article Type] Multicenter Study
Prioritizing Surgical Services during on-Going Pandemic Response: Modification and Reliability of the Medically Necessary Time Sensitive Surgery (MeNTS) Scoring ToolSystems-Level Quality Improvement Published on 2021-04-072022-10-29 Journal: Journal of medical systems [Category] Coronavirus, MERS, SARS, [키워드] Analysis approach assessments assumed cardiovascular disease Care center clinician Cohort COVID Critically ill patient Decision-tool demonstrated Department diabetes evaluated expand female Final healthcare Healthcare resources hospital Hospital administration ICC indication initial invasive iterative Los Angele Lung disease majority multicenter Normal distribution Olive operative organ over pandemic Patient Pelvic performed predominant Quantitative Range reliability Scoring sensitive service surgery surgical Surgical services the patient time university uterine bleeding vaginal surgery View Volume with COVID-19 [DOI] 10.1007/s10916-021-01731-w PMC 바로가기 [Article Type] Systems-Level Quality Improvement
Comparing Visual Scoring of Lung Injury with a Quantifying AI-Based Scoring in Patients with COVID-19Original Article Published on 2021-04-052022-10-30 Journal: Journal of the Belgian Society of Radiology [Category] COVID-19, [키워드] Analysis artificial intelligence software category correlation correlation coefficient COVID-19 COVID-19 patients COVID-19 positive patient dataset deep learning deep learning-based software Diagnosis estimate evaluate FIVE help high-risk patient indicate lobar lung Lung injury Lung Opacity material median age men outbreak pandemic quantification Retrospective study Scoring scoring system severity severity index Visual visual scoring was obtained with COVID-19 women [DOI] 10.5334/jbsr.2330 PMC 바로가기 [Article Type] Original Article
Chest CT Diagnosis of COVID-19: Accuracy using CO-RADS and CT-Involvement ScoringOriginal Article Published on 2021-04-052022-10-30 Journal: Journal of the Belgian Society of Radiology [Category] COVID-19, [키워드] Accuracy approach Assessing assigned calculated Chest Chest CT Clinical diagnosis CO-RADS Course COVID-19 COVID-19 infection CT CT scan dataset diagnose diagnostic Diagnostic accuracy diagnostic value evaluate explained False-positive Final highest Infection initial material Nasopharyngeal swab Negative predictive value NPV polymerase chain reached Reporting respiratory symptom Retrospective study reverse transcription RT-PCR Scoring scoring system sensitivity single-center specificity System the disease [DOI] 10.5334/jbsr.2342 PMC 바로가기 [Article Type] Original Article
Evaluation of lung involvement in COVID-19 pneumonia based on ultrasound images초음파 영상을 기반으로 한 코로나19 폐렴의 폐 침범 평가Research Published on 2021-03-202022-09-01 Journal: BioMedical Engineering OnLine [Category] 진단, [키워드] Accuracy automatically can be used classification COVID-19 COVID-19 pneumonia damage deep learning determine Diagnosis diagnostic evaluate evaluated feature FUSE initial lung involvement Lungs multicenter network Neural network patients Pneumonia Precision receptive field rehabilitation Result Scoring sensitivity severity sonogram specificity Ultrasound [DOI] 10.1186/s12938-021-00863-x PMC 바로가기 [Article Type] Research
Development and Validation of a Clinical Symptom-based Scoring System for Diagnostic Evaluation of COVID-19 Patients Presenting to Outpatient Department in a Pandemic SituationFamily/General Practice Published on 2021-03-032022-10-31 Journal: Cureus [Category] COVID-19, [키워드] 1.26 95% confidence interval adjusted odds ratio analysed Analysis association can be used clinical clinical suspicion clinical symptom Clinical symptoms conducted cough COVID-19 COVID-19 pandemic cut-off dataset Department develop development Diagnosis diagnosis of COVID-19 diagnostic evaluated external validation Fever headache Isolation Loss of Smell myalgia Outpatient outpatient clinic Patient patients predictor presenting presenting symptom receiver operating characteristics Result risk stratification ROC ROC Curve RT-PCR score Scoring scoring system Screening sensitivity situation statistically significant suspected patient Symptom System total patients validation was determined [DOI] 10.7759/cureus.13681 PMC 바로가기 [Article Type] Family/General Practice