SARS-CoV-2 genome quantification in wastewaters at regional and city scale allows precise monitoring of the whole outbreaks dynamics and variants spreading in the population지역 및 도시 규모의 폐수에서 SARS-CoV-2 게놈 정량화를 통해 인구에 확산되는 전체 발병 역학 및 변이체를 정밀하게 모니터링할 수 있습니다.Article Published on 2022-03-012022-09-11 Journal: The Science of the total environment [Category] SARS, 변종, [키워드] approach Asymptomatic average B.1.1.7 cause Cluster collected coronavirus correlation country COVID-19 COVID-19 outbreak decision Deletion Epidemiology FIVE France Genome greater Health health monitoring Health status help highlight implementation incidence incidence rates individual Infection inhalation Lead time limitations Local measure observé outbreak overcome pandemic Paris Patient performed plant predominant proportion quantification Quantitative analysis respiratory droplet Respiratory droplets RT-qPCR SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 transmission selection pressure sensitivity severe complications sewer Spike protein Stool the spike protein today Treatment variant Variant monitoring variants variants of concern virus transmission VoC wastewater [DOI] 10.1016/j.scitotenv.2021.152213 PMC 바로가기 [Article Type] Article
Evolution of resistance to COVID-19 vaccination with dynamic social distancing Research Published on 2022-02-242022-10-05 Journal: Nature human behaviour [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, [키워드] Affect booster Contact COVID-19 COVID-19 pandemic COVID-19 vaccination evolutionary dynamics Factor Infection mutant prevented Probability reduction response to vaccination selection pressure social distancing Transmissibility vaccination Vaccine Vaccine design Vaccine hesitancy Vaccine-resistant variants virus [DOI] 10.1038/s41562-021-01281-8 [Article Type] Research
The ins and outs of SARS-CoV-2 variants of concern (VOCs)SARS-CoV-2 관련 변종(VOC)의 내부 및 외부Review Published on 2022-02-012022-09-11 Journal: Archives of Virology [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] caused Characteristics coronavirus COVID-19 epidemic diagnostics disease Economy effective extreme greater transmissibility Health health workers Host Immune escape Immunity immunization Mortality mortality risk mutate new SARS-CoV-2 patients regimens SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants selection pressure severe disease therapeutic Transmissibility variant variants variants of concern VoC VOCs Wuhan strain [DOI] 10.1007/s00705-022-05365-2 PMC 바로가기 [Article Type] Review
Molecular Characterization of Infectious Bronchitis Virus Strain HH06 Isolated in a Poultry Farm in Northeastern ChinaVeterinary Science Published on 2021-12-162022-11-01 Journal: Frontiers in Veterinary Science [Category] COVID-19, [키워드] Analysis bovine characterization characterized China clade clades coronavirus Coronaviruses CoV CoVs domain Epidemic Evolution explain farm Genetic Genome glycoprotein HCoV-OC43 Host IBV indicated Infectious Bronchitis Virus Isolated maintain mammalian MERS-CoV Molecular epidemiology motif Phylogenetic Phylogenetic relationship poultry protein sequence Recombination S gene S protein SARS CoV-2 SARS-CoV SARS-CoV-2 selected selection pressure sequence spike Spread strain variant virulent viruses zoonosis [DOI] 10.3389/fvets.2021.794228 PMC 바로가기 [Article Type] Veterinary Science
Epidemiology and Evolution of Emerging Porcine Circovirus-like Viruses in Pigs with Hemorrhagic Dysentery and Diarrhea Symptoms in Central China from 2018 to 20212018년부터 2021년까지 중앙 중국에서 출혈성 이질 및 설사 증상을 보이는 돼지에서 발생한 새로운 포르시네 서클로바이러스 유사 바이러스의 역학 및 진화Article Published on 2021-11-152024-07-30 Journal: Viruses [Category] 세균성이질, [키워드] Central China porcine circovirus-like virus pregnant sows Recombination selection pressure [DOI] 10.3390/v13112282 PMC 바로가기 [Article Type] Article
Host Response to SARS-CoV2 and Emerging Variants in Pre-Existing Liver and Gastrointestinal Diseases기존 간 및 위장 질환의 SARS-CoV2 및 새로운 변이체에 대한 숙주 반응Review Published on 2021-10-252022-09-11 Journal: Frontiers in Cellular and Infection Microbiology [Category] MERS, SARS, 변종, 치료기술, [키워드] accumulation ACE2 receptor Alpha Alter Altered B.1.1.28.1 B.1.1.7 B.1.351 Beta binding Brazil changes in characteristic CLARITY cleavage condition coronavirus COVID-19 cytokine Cytokine storm Definitive determinant diabetes disease Diseases disorder disorders distribution drastic E484K emerging variants expression feature finding First wave Gastrointestinal gastrointestinal disease Generation GI Tract Host Host immune response host protease host protease TMPRSS2 host response hypertension Immune escape Immune status immunocompromised condition immunomodulation implicated incidence India indicate Infection Inflammation L452R lack less liver liver failure Liver injury manifestation Manifestations mechanism Mild Mortality Mutation N501Y novel Novel coronavirus obesity occur organs outcome outcomes P681R pandemic Patient predominant Protein binding radiologic receptor Receptor binding Replication reported required response risk factor RNA SARS-CoV2 selection pressure several variant several variants severe COVID-19 shown South Africa Spike protein Stool Symptoms systemic inflammation the disease the spike protein tissue expression TMPRSS2 Transmissibility Transmission underlying disease underlying diseases variant variants variants of concern Viral viral entry viral genome Viral proteins Viremia virulence virus virus clearance VoC [DOI] 10.3389/fcimb.2021.753249 PMC 바로가기 [Article Type] Review
Study on the Characteristic Codon Usage Pattern in Porcine Epidemic Diarrhea Virus Genomes and Its Host Adaptation PhenotypeOriginal Research Published on 2021-10-182023-08-30 Journal: Frontiers in Microbiology [Category] E형 간염, [키워드] codon usage coronavirus host adaptation PEDV selection pressure viral evolution [DOI] 10.3389/fmicb.2021.738082 PMC 바로가기 [Article Type] Original Research
Coronavirus Disease 2019 Vaccine Impact on Rates of Severe Acute Respiratory Syndrome Coronavirus 2 Cases and Postvaccination Strain Sequences Among Health Care Workers at an Urban Academic Medical Center: A Prospective Cohort StudyMajor Articles Published on 2021-10-172022-10-29 Journal: Open Forum Infectious Diseases [Category] COVID-19, [키워드] acute respiratory syndrome antibody escape mutations Asymptomatic Breakthrough infection Community Confidence intervals confirmed case coronavirus coronavirus 2 Coronavirus disease 2019 COVID-19 COVID-19 vaccine decrease dose dropped first dose genetic diversity Genome HCW HCWs Health care worker Impact infection control infections initial injection isolate Latinx mRNA-1273 Mutation occurred of BNT162b2 Older positive Prevalence Prospective prospective cohort study Rate rate ratio respiratory Result SARS-CoV-2 SARS-CoV-2 infections selection pressure sequence sequenced Spike protein strain urban vaccination Vaccine vaccine doses vaccine trial viral evolution Weekly Whole genome sequencing with COVID-19 worker [DOI] 10.1093/ofid/ofab465 PMC 바로가기 [Article Type] Major Articles
Targeting novel coronavirus SARS-CoV-2 spike protein with phytoconstituents of Momordica charantiaMomordica Charantia의 식물성 분열제를 갖는 소설 코로나 바이러스 SARS-COV-2 스파이크 단백질 표적Research Published on 2021-09-272022-08-31 Journal: Journal of Ovarian Research [Category] SARS, 변종, 치료제, [키워드] active site ADME Affect binding binding affinity binding energy Bitter Bitter melon component Compound COVID-19 docking Docking studies docking study domain drug effort Erythrodiol evaluate hydrophilic hydrophobic hydrophobic interactions identify in-silico infection rate Interaction Melon Momordica Momordica Charantia novel coronavirus SARS-CoV-2 PyMol reduce Result reveal S1 and S2 S1 and S2 domains SARS-CoV-2 SARS-CoV-2 spike protein SARS-CoV-2 viral infection SARS-CoV-2 virus selection pressure Spike protein Spike proteins SPR strong interactions surface plasmon surface plasmon resonance targeting tested the SARS-CoV-2 the SARS-CoV-2 virus the spike protein treat vaccination variant Viral viral infections was used were used [DOI] 10.1186/s13048-021-00872-3 PMC 바로가기 [Article Type] Research
Higher entropy observed in SARS-CoV-2 genomes from the first COVID-19 wave in Pakistan파키스탄의 첫 번째 코비드 -19 파에서 SARS-COV-2 게놈에서 관찰 된 더 높은 엔트로피Research Article Published on 2021-08-312022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 변종, [키워드] (RdRp 5’ UTR Analysis B.1 B.6 Capital change clade clades COVID-19 D614G Diversity Evolution except for exhibited Genetic Genome genome sequence genomes glycoprotein highest investigated isolates Laboratory lead material Mutation mutation rate Mutation rates not significant pandemic Phylogeny Q57H RdRP relative Result RNA RNA dependent RNA polymerase RNA polymerase SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genomes SARS-CoV-2 strain SARS-CoV-2 strains selection pressure sequence sequences Site spike spike glycoprotein stability strain Strains subsequent territory transmitted virus were used [DOI] 10.1371/journal.pone.0256451 PMC 바로가기 [Article Type] Research Article