COVID-profiler: a webserver for the analysis of SARS-CoV-2 sequencing dataCOVID-profiler: SARS-CoV-2 시퀀싱 데이터 분석을 위한 웹 서버Article Published on 2022-04-152022-09-11 Journal: BMC Bioinformatics [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] Analysis applied assist COVID-19 pandemic diagnostics genomic data Mutation NGS Pathogens Phylogenetic analysis phylogenetics Quality control resulting robust SARS-CoV-2 SARS-CoV-2 sequencing SARS-CoV-2 virus Sequencing sequencing data serological assays source code Spread Vaccines [DOI] 10.1186/s12859-022-04632-y PMC 바로가기 [Article Type] Article
Diagnosing COVID-19; towards a feasible COVID-19 rule-out protocolCOVID-19 진단; 실현 가능한 COVID-19 배제 프로토콜을 향해Article Published on 2022-04-012022-09-11 Journal: Acta clinica Belgica [Category] COVID19(2023년), SARS, 치료기술, [키워드] added Analysis antibody Antibody testing approach BAL BAL fluid bronchoalveolar Bronchoalveolar lavage bronchoscopy Chest CT COVID-19 COVID-19 in patient COVID-19 negative COVID-19 positive patients Critically ill Culture decrease diagnoses diagnostics etiological agent feasible Ghent identify IgA IgG implementation initial invasive low-dose microbial multiplex Multiplex PCR negativity non-critically ill patient Pathogens Patient positive protocol repeated respiratory pathogen Retrospective analysis rRT-PCR RT-PCR SARS-CoV-2 SARS-COV-2 infection selected Serological assay serological assays serology Symptom university [DOI] 10.1080/17843286.2021.1883362 PMC 바로가기 [Article Type] Article
Sensitive and specific serological ELISA for the detection of SARS-CoV-2 infectionsSARS-CoV-2 감염 검출을 위한 민감하고 특이적인 혈청학적 ELISAArticle Published on 2022-03-192022-09-11 Journal: Virology Journal [Category] SARS, 치료기술, 치료법, [키워드] 113 patient 113 patients 95% CI acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibody antibody levels Antibody titer Antibody titers approved Asymptomatic collected coronavirus coronavirus disease Coronavirus disease 2019 Coronavirus disease 2019 (COVID-19) COVID-19 cytomegalovirus develop early phase ELISA enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay Enzyme-linked immunosorbent assay (ELISA) epidemiological data Epstein Barr virus Escherichia coli Hepatitis herpes simplex herpes simplex virus hospitalized COVID-19 patient hospitalized COVID-19 patients human serum identify IgG antibodies IgG immune response immune response immunodeficiency Infection Mild N-protein nucleocapsid protein Nucleocapsid protein (N-protein) number of infected pandemic Pathogens Patient PCR positive PCR test produced Protein provided purified remained RT-PCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 nucleocapsid SARS-CoV-2 specific antibodies SARS-CoV-2 spike sensitive sensitivity sera serological serological assays serological test serum sample serum samples severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) severe symptom severe symptoms specific IgG antibody specificity symptom onset symptomatic infections tested the SARS-CoV-2 triggered Vaccine virus [DOI] 10.1186/s12985-022-01768-4 PMC 바로가기 [Article Type] Article
Risk of Reinfection After Seroconversion to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): A Population-based Propensity-score Matched Cohort Study중증 급성 호흡기 증후군 코로나바이러스 2(SARS-CoV-2)로의 혈청전환 후 재감염 위험: 인구 기반 성향 점수 일치 코호트 연구Article Published on 2022-03-012022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] MERS, SARS, 진단, 치료기술, [키워드] 95% confidence interval acute respiratory syndrome acute respiratory syndrome coronavirus age antibody BMI body mass body mass index Clinical practice conducted controls coronavirus coronavirus 2 COVID-19 Effectiveness Follow-up follow-up period Gender hazard health authorities Health authority help immune response immunodeficiency incidence individual Infection infection rate Matched pandemic participant Participants positive Primary outcome priority protection reduction in Reinfection respiratory retrospective SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 test selected Seroconversion serological serological assays seronegative seropositive individual seropositive individuals seropositive participants seropositive subject seropositive subjects seroprevalence survey Serosurvey smoking status Standard deviation Switzerland Vaccine [DOI] 10.1093/cid/ciab495 PMC 바로가기 [Article Type] Article
Diagnostic Performance of Seven Commercial COVID-19 Serology Tests Available in South America남미에서 사용 가능한 7개의 상업용 COVID-19 혈청 검사의 진단 성능Cellular and Infection Microbiology Published on 2022-02-182022-09-11 Journal: Frontiers in Cellular and Infection Microbiology [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] Accuracy alternative anti-SARS-CoV-2 anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 IgG anti-SARS-CoV-2 IgM blind evaluation collected conducted COVID-19 COVID-19 diagnosis Diagnosis diagnostic Ecuador ELISA ELISA kit ELISA kits ELISAs enzyme-linked immunosorbent assay enzyme-linked immunosorbent assays FIVE Infection lack lateral-flow immunoassay LFIA LFIAs lowest objective performance Positive test qPCR Rapid test Result RT-qPCR SARS-CoV-2 sensitivity serological assays serological test Serological tests serology Seven significantly higher South America specificity statistically significant difference Test tested [DOI] 10.3389/fcimb.2022.787987 PMC 바로가기 [Article Type] Cellular and Infection Microbiology
SARS-CoV-2 Seroprevalence in Healthcare Workers before the Vaccination in Poland: Evolution from the First to the Second Pandemic Outbreak폴란드에서 예방 접종 전 의료 종사자의 SARS-CoV-2 혈청 유병률: 첫 번째 전염병 발생에서 두 번째 유행성 발병으로의 진화Article Published on 2022-02-172022-09-12 Journal: International Journal of Environmental Research an [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] 95%CI acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 All participants anti-SARS-CoV-2 association caused center community transmission coronavirus coronavirus disease COVID-19 demonstrated determine ELISA exhibited Factor HCW HCWs healthcare worker Healthcare workers hospital IgA IgG IgG/IgA seroprevalence immune response infections investigated Medicine Nurse Nurses occupational occupational medicine outbreak pandemic participant Participants questionnaire Regional reported Risk factors SARS-CoV-2 SARS-CoV-2 seroprevalence second second wave Serological assay serological assays Seropositivity Seroprevalence severe acute respiratory syndrome Coronavirus Severity of infection significant increase were used women worker [DOI] 10.3390/ijerph19042319 PMC 바로가기 [Article Type] Article
Performance evaluation of an automatic chemiluminescence immune platform for SARS-CoV-2 neutralizing antibody after vaccination in real worldSARS-COV-2를위한 자동 화학 발광 면역 플랫폼의 성능 평가 현실에서 예방 접종 후 항체Research Published on 2022-02-152022-09-01 Journal: BMC Infectious Diseases [Category] COVID19(2023년), Fulltext, MERS, SARS, 진단, [키워드] Adolescent BBIBP-CorV changes in Characteristics chemiluminescence China CLIA Cohort CoronaVac doses evaluated exceeded Follow-up followed by Hemolysis high correlation icterus immune immunity after vaccination immunoassays inactive injection inoculation investigated less linearity lipemia measure Neutralizing activity Neutralizing antibodies neutralizing antibody objective occurred performance Physical examination Plaque reduction neutralization test platform predominant PRNT Real world recipient recruited repeatability Result robust SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-CoV-2 neutralizing antibodies SARS-CoV-2 neutralizing antibody SARS-CoV-2 vaccine schedule Sensitivity and specificity Serological assay serological assays seropositive Shenzhen significantly lower Sinovac strength Trial vaccination Vaccination Status Vaccinations Vaccine Variation volunteers [DOI] 10.1186/s12879-022-07141-8 PMC 바로가기 [Article Type] Research
Reinfection by the SARS-CoV-2 Gamma variant in blood donors in Manaus, Brazil브라질 마나우스의 헌혈자의 SARS-COV-2 감마 변종에 의한 재감염Research Published on 2022-02-052022-09-10 Journal: BMC Infectious Diseases [Category] COVID19(2023년), Fulltext, MERS, SARS, 변종, 치료기술, [키워드] 95% CI Amazon anti-SARS-CoV-2 antibody anti-SARS-CoV-2 IgG anti-SARS-CoV-2 IgG antibodies anti-SARS-CoV-2 IgG antibody blood donor Blood donors blood sample Brazil caused city COVID-19 criteria defined Donor donors Early convalescence epidemic wave Epidemics estimates events Gamma Genome sequencing group herd immunity highlighting IgG antibodies include inclusion criteria Infection Manaus P.1 percentage prevalent proportion reactivity Reinfection Reinfections required Result RT-PCR test SARS-CoV-2 second wave sequence serological serological assays supplementary material tested the SARS-CoV-2 variant variants variants of concern Volume were used [DOI] 10.1186/s12879-022-07094-y PMC 바로가기 [Article Type] Research
In Planta Production of the Receptor-Binding Domain From SARS-CoV-2 With Human Blood Group A Glycan StructuresChemistry Published on 2022-02-012022-10-31 Journal: Frontiers in Chemistry [Category] COVID-19, [키워드] ACE2 receptor Affect Analysis antibody Antigen approach benthamiana binding Blood Group Blood group antigen carbohydrate cellular co-expressed complex contribute CR3022 domain ENhance Epitopes functional glycan glycoengineering glycosylated glycosylation group Human human sera IgG immune evasion immunogenic in vivo individual Interaction Modification N-glycan Nicotiana benthamiana non-infected performed plants posttranslational modification Production purified RBD recombinant SARS-CoV-2 SARS-CoV-2 RBD SARS-CoV-2 spike protein sera serological assays shown Structure structures Subunit vaccine the RBD the SARS-CoV-2 variant Viral antigen viral envelope protein virus virus infection virus transmission [DOI] 10.3389/fchem.2021.816544 PMC 바로가기 [Article Type] Chemistry
A quantitative assay for detection of SARS-CoV-2 neutralizing antibodiesSARS-CoV-2 중화 항체 검출을 위한 정량 분석Article Published on 2022-02-012022-09-11 Journal: Journal of Clinical Virology [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, [키워드] 95% CI Alpha analyzed antibody Chorus Concordance COVID-19 Critical cross reaction diagnosis of COVID-19 diagnostic assay evaluate evaluated False negative False positives human serum IgA IgG IgM immunoassay Infection neutralization Neutralizing Neutralizing antibodies neutralizing antibody no significant differences other respiratory infection other respiratory infections patients positive Post-infection quantitative assay quantitative determination respiratory respiratory infections SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 neutralizing antibodies SARS-CoV-2 neutralizing antibody SARS-CoV-2 virus sensitivity Sensitivity and specificity sera serological assays significant difference significant differences specific antibodies specific antibody specificity subjects symptomatic tracer Trio uninfected vaccination value variants virus were used [DOI] 10.1016/j.jcv.2021.105064 PMC 바로가기 [Article Type] Article