Intravenous immunoglobulin treatment for patients with severe COVID-19: a retrospective multicentre study중증 코로나19 환자를 위한 정맥 면역글로불린 치료: 다기관 후향적 연구Multicenter Study Published on 2021-10-012022-09-12 Journal: Clinical microbiology and infection : the official [Category] MERS, SARS, 진단, 치료법, [키워드] 28-day mortality 95% CI Acute kidney injury acute respiratory distress Analysis average Clinical outcome confounding factors COVID-19 Effectiveness evaluated extracorporeal membrane oxygenation hepatic injury Immunoglobulin intravascular coagulation Intravenous immunoglobulin Invasive mechanical ventilation investigated IPW mechanical ventilation Mortality multicentre myocardial injury no significant difference Non-invasive Patient patients Probability Prone position remained renal replacement therapy retrospective severe severe COVID-19 severe COVID-19 patient severe COVID-19 patients Shock significant changes in significant difference syndrome treat treated Treatment Ventilation Weighting were used [DOI] 10.1016/j.cmi.2021.05.012 PMC 바로가기 [Article Type] Multicenter Study
Clinical and laboratory findings and PCR results in severe and non-severe COVID19 patients based on CURB-65 and WHO severity indices임상 및 실험실 소견 및 PCR은 CURB-65를 기준으로 심각하고 비 체위 COVID 19 명의 환자를 초래하고 WHO 중증도 지수를 초래합니다.Research Published on 2021-09-172022-09-01 Journal: Virology Journal [Category] SARS, 진단, [키워드] abnormality Admission Alborz appear Asthma categories Characteristics CHD chronic heart disease clinical Clinical and laboratory findings Clinical characteristics Clinical features Comorbidities compatibility COVID-19 COVID19 patient cross-sectional CURB CURB-65 diabetes Diagnosis diagnosis of COVID-19 distribution FIVE Frequency group groups guideline heart disease Hospitalized hospitalized patient hospitalized patients hyperlipidemia hypertension inclusion criteria initial Inpatients involved Iran Laboratory laboratory findings nausea no significant difference Non-severe non-severe cases non-severe group outpatients outpatients and inpatient oxygen oxygen saturation Patient PCR positive Result rRT-PCR severe severe and non-severe cases severity significant difference Signs and symptoms Symptom symptomatic adult Symptoms the disease Treatment Trial two group two groups vital sign vital signs was performed WHO with COVID-19 [DOI] 10.1186/s12985-021-01658-1 PMC 바로가기 [Article Type] Research
Monitoring Specific IgM and IgG Production Among Severe COVID-19 Patients Using Qualitative and Quantitative Immunodiagnostic Assays: A Retrospective Cohort Study정성적 및 정량적 면역진단 분석을 사용하여 중증 COVID-19 환자 중 특정 IgM 및 IgG 생산 모니터링: 후향적 코호트 연구Immunology Published on 2021-09-032022-09-11 Journal: Frontiers in Immunology [Category] SARS, 진단, 치료기술, 치료법, [키워드] Abbott acute respiratory syndrome analyzed anti-SARS-CoV-2 anti-SARS-CoV-2 IgG antibody production Architect assays association Cohen’s kappa coefficient Combination Concentration concentrations confirmed COVID-19 patients coronavirus coronavirus disease Coronavirus disease 2019 correlation COVID-19 COVID-19 patient develop Diagnosis early phase form humoral immune response IgG IgG and IgM IgG test IgM IgM and IgG IgM antibody IgM seroconversion immunoassays immunoglobulins MONITOR monitoring Mortality Patient Pearson correlation coefficient performed positive positive relationship processed Production Qualitative Quantitative respiratory robust SARS-CoV-2 SARS-CoV-2 IgG Saudi Arabia sera seroconversion rate seroconversion rates Serological testing serum severe severe COVID-19 severity of COVID-19 Specific test results tested [DOI] 10.3389/fimmu.2021.705441 PMC 바로가기 [Article Type] Immunology
Biomarkers of severe COVID-19 pneumonia on admission using data-mining powered by common laboratory blood tests-datasets일반적인 실험실 혈액 검사 데이터 세트로 구동되는 데이터 마이닝을 사용하여 입원 시 중증 COVID-19 폐렴의 바이오마커Article Published on 2021-09-012022-09-11 Journal: Computers in biology and medicine [Category] MERS, SARS, 바이오마커, [키워드] acid-base balance Admission Algorithm analyzed approach artificial intelligence best Biomarkers Blood blood gas Blood gas analyses C-reactive protein clinical laboratory Clinical laboratory techniques clinical outcomes Clustering complex conducted correlation COVID-19 COVID-19 patient COVID-19 patients COVID-19 pneumonia COVID-19 research Data mining dataset datasets Decision tree disease severity epidemiological feature fluctuation form Glucose group hematological Hemogram hidden Hierarchical high risk Hypoxemia Inflammation investigated involved knowledge Laboratory Laboratory tests leukocyte limitation lymphocyte machine machine learning Medical Informatics Applications neutrophil on admission PaO Pearson perceptron performed Pneumonia Precision predict processed Protein Prothrombin time R software severe severe COVID-19 Severe COVID-19 pneumonia severity skill supervised learning therapeutic targets unique variable [DOI] 10.1016/j.compbiomed.2021.104738 PMC 바로가기 [Article Type] Article
Early, short-term, low-dose glucocorticoid therapy effectively blocks progression of severe acute exacerbation of chronic hepatitis B to liver failureRandomized Controlled Trial Published on 2021-09-012023-06-13 Journal: Clinics and research in hepatology and gastroenter [Category] B형 간염, [키워드] glucocorticoid Hepatitis B, chronic severe [DOI] 10.1016/j.clinre.2020.07.010 [Article Type] Randomized Controlled Trial
Evaluation of Biomarkers of Severity in Patients with COVID-19 InfectionArticle Published on 2021-08-242022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] abnormality Admission albumin Biomarker Biomarkers C-reactive protein coagulation time coronavirus disease COVID-19 COVID-19 patient CRP differential diagnosis disease severity disease stages Diseases examined ferritin Frequency hemoglobin Japanese laboratory biomarker lactate dehydrogenase LDH marker median age Mild mild symptoms moderate mortality rate outcome Patient patients PCT procalcitonin Protein resulting ROC analysis severe severe COVID-19 severe disease severity significantly stages with COVID-19 worsening [DOI] 10.3390/jcm10173775 PMC 바로가기 [Article Type] Article
Efficacy and safety of remdesivir in hospitalized Covid-19 patients: Systematic review and meta-analysis including network meta-analysisReview Published on 2021-07-012023-07-06 Journal: Reviews in Medical Virology [Category] SARS, [키워드] clinical trials COVID-19 moderate Remdesivir Safety SARS-CoV-2 severe [DOI] 10.1002/rmv.2187 [Article Type] Review
Serum IL-6 and procalcitonin are two promising novel biomarkers for evaluating the severity of COVID-19 patients혈청 IL-6 및 프로칼시토닌은 COVID-19 환자의 중증도를 평가하기 위한 두 가지 유망한 신규 바이오마커입니다Observational Study Published on 2021-06-042022-09-11 Journal: Medicine [Category] SARS, 바이오마커, 임상, [키워드] Analysis Biomarker consecutive patient coronavirus disease Coronavirus disease 2019 COVID-19 Critical diagnose diagnosis of COVID-19 evaluate group groups highest IL-6 IL-6 level IL-6 levels interleukin interleukin 6 interleukin 6 (IL-6 lowest Patient PCT procalcitonin Serum IL-6 severe severity of COVID-19 significant difference significantly were assessed [DOI] 10.1097/MD.0000000000026131 PMC 바로가기 [Article Type] Observational Study
SARS-CoV-2 elicits robust adaptive immune responses regardless of disease severityResearch Paper Published on 2021-06-042023-06-16 Journal: EBioMedicine [Category] MERS, SARS, [키워드] adaptive antibody Asymptomatic CD8+ T-cell Corona COVID-19 immune response SARS-CoV-2 severe virus [DOI] 10.1016/j.ebiom.2021.103410 PMC 바로가기 [Article Type] Research Paper
Clinical Characteristics and Abnormal Parameters Evolution in Patients With Novel Coronavirus Infection: A Case Series of 272 Cases in GuangzhouOriginal Research Published on 2021-05-182022-10-31 Journal: Disaster Medicine and Public Health Preparedness [Category] COVID-19, [키워드] activated Admission age Blood routine C-reactive protein changed changes in Characteristics clinical Clinical characteristics collected continuous change coronavirus disease cough COVID-19 D-dimer diagnosed with COVID-19 Disease progression enrolled Epidemic Evidence female Fever fibrinogen Guangzhou hypertension imaging examination lab laboratory parameter lactate dehydrogenase male Mild novel Older age other diseases Patient patients positive procalcitonin raised Risk factors Sery severe severe disease severe patients suffered the patient Wuhan [DOI] 10.1017/dmp.2021.149 PMC 바로가기 [Article Type] Original Research