Skin manifestations of COVID-19 in children: Part 3어린이의 COVID-19 피부 발현: 파트 3Review Published on 2021-04-012022-09-12 Journal: Clinical and experimental dermatology [Category] MERS, SARS, 진단, [키워드] affected article caused childhood children conditions coronavirus Course COVID-19 COVID-19 pandemic Critical cutaneous manifestation death Europe European country histological infected children Inflammatory initial Italian Italy knowledge lesions management Manifestations multisystemic outcome pandemic Part SARS-COV-2 infection Severe respiratory distress skin manifestation Symptom syndrome the SARS-CoV-2 Ventilation widespread [DOI] 10.1111/ced.14483 PMC 바로가기 [Article Type] Review
Levels of Soluble CD14 and Tumor Necrosis Factor Receptors 1 and 2 May Be Predictive of Death in Severe Coronavirus Disease 2019가용성 CD14 및 종양 괴사 인자 수용체 1 및 2의 수준은 심각한 코로나바이러스 질병 2019에서 사망을 예측할 수 있음Article Published on 2021-03-032022-08-31 Journal: The Journal of Infectious Diseases [Category] 바이오마커, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus asymptomatic infection CD14 coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Critical Critical disease death died disease disease severity Factor fatty Fatty acid Hospital admission individual individuals Inflammation Level Mild moderate monocyte Monocyte activation Monocytes Necrosis Patient Protein receptor respiratory respiratory distress resulting SARS-CoV-2 serum biomarker serum biomarkers severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Severe respiratory distress TNFR1 TNFR2 Tumor tumor necrosis tumor necrosis factor uninfected [DOI] 10.1093/infdis/jiaa744 PMC 바로가기 [Article Type] Article
Calming the inflammatory storm in severe COVID-19 infections: Role of biologics- A narrative reviewReview article Published on 2021-03-012022-10-05 Journal: Saudi Pharmaceutical Journal : SPJ [Category] 신약개발, [키워드] Activation affected chemokine Complication COVID-19 COVID-19 patient COVID-19 patients cytokine Cytokine storm death Factor Genes GM-CSF GM-CSF inhibitors help hyper inflammation IL-6 IL-6 antagonist IL-6 inhibitors IL-6 receptor antagonists Immune cell immune cells immune response implicated include indicate Infection Inflammatory cytokine inflammatory storm inhibitor intravascular coagulation investigated involved Jak-STAT JAK-STAT inhibitors Janus kinase lack Lung injury management mitigate Mortality multi-organ failure neutralization pathway Prevent Protein receptor inhibitors risk role severe COVID-19 Severe COVID-19 Infection severe COVID-19 patient Severe respiratory distress severity STAT survival the cytokine storm therapeutic therapeutic strategy Transcription triggering [DOI] 10.1016/j.jsps.2021.01.005 [Article Type] Review article
At the Crossroads: COVID-19 and Immune-Checkpoint Blockade for Cancer갈림길에서: COVID-19와 암에 대한 면역 관문 차단Article Published on 2021-03-012022-09-11 Journal: Cancer immunology research [Category] 바이오마커, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antiviral immune response antiviral immune responses blockade Cancer Characteristics clinical trials Complication complications of COVID-19 coronavirus coronavirus disease Coronavirus disease 2019 Course COVID-19 COVID-19 infection COVID-19 pandemic COVID-19 vaccination death decrease detrimental disease course Effect Evidence expression heterogeneity immune responses immunomodulatory effect immunomodulatory effects infections Inflammatory inflammatory complications Inflammatory response Inflammatory responses interferon interferon signaling leads Ligand MOST pathway Patient patients Patients with cancer PD-L1 PD1 PROTECT provided receiving receptor respiratory respiratory distress Respiratory distress syndrome RNA virus SARS-CoV-2 severe acute respiratory syndrome Coronavirus Severe case severe cases Severe respiratory distress Support syndrome the disease therapy Viral viral infection virus infections worsening [DOI] 10.1158/2326-6066.CIR-21-0008 PMC 바로가기 [Article Type] Article
Drug Repurposing in the COVID-19 Era: Insights from Case Studies Showing Pharmaceutical PeculiaritiesReview Published on 2021-02-252022-10-28 Journal: Pharmaceutics [Category] COVID-19, [키워드] administration Antiviral Antiviral effect approved benefit chloroquine/hydroxychloroquine Clinical improvement COVID-19 death dietary supplements drug Drug repurposing drugs effective Efficacy heparin high risk highlight Hydroxychloroquine insight Lopinavir/ritonavir Mortality Older Ozone patients pharmaceutical pharmaceutical formulations pharmacokinetic phosphodiesterase inhibitors potential treatments reduced risk Regulatory Remdesivir reported repurposing Safe safety profile Severe respiratory distress syndrome tested treatments for COVID-19 [DOI] 10.3390/pharmaceutics13030302 PMC 바로가기 [Article Type] Review
Probiotics potentials in mitigating coronavirus disease (COVID-19) pandemicCommentary Published on 2021-02-182022-10-28 Journal: The Pan African Medical Journal [Category] COVID-19, MERS, [키워드] administration Compound coronavirus disease COVID-19 COVID-19 pandemic exclusion gastrointestinal tract Health human infectious disease immune response immune responses Infection prevention lack Measures microbiota mitigate modulate modulation morbidities morbidity mortalities pandemic Pathogens prevention Probiotics reduction in secretion Severe respiratory distress shown therapeutic intervention [DOI] 10.11604/pamj.2021.38.186.27953 PMC 바로가기 [Article Type] Commentary
SARS-CoV-2 tropism, entry, replication, and propagation: Considerations for drug discovery and developmentSARS-CoV-2 지향성, 진입, 복제 및 전파: 약물 발견 및 개발에 대한 고려 사항Review Published on 2021-02-172022-08-13 Journal: PLoS Pathogens [Category] Biochemistry, COVID-19, MERS, [키워드] acute respiratory syndrome coronavirus antiviral activity appear cellular infection systems cellular interaction Compound coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 disease drug Drug discovery Effect effort food framework Hospitalization identify immortalized cell line in vitro initial involved knowledge Mild symptom mild symptoms molecular Mortality Non-pulmonary nonhuman immortalized cell lines Novel coronavirus novel coronavirus disease physiological question Remdesivir Replication respiratory respiratory distress SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Severe respiratory distress Spread Support treatments for COVID-19 virus while Wuhan Wuhan, China [DOI] 10.1371/journal.ppat.1009225 PMC 바로가기 [Article Type] Review
A Case Series on Critically Ill Pregnant or Newly Delivered Patients with Covid-19, Treated at Karolinska University Hospital, StockholmCase Series Published on 2021-02-102022-10-31 Journal: Case Reports in Obstetrics and Gynecology [Category] COVID-19, [키워드] Admission Antenatal average C-section Cardiomyopathy compose computer tomography cough Critically ill demonstrated develop discharged Dyspnea Echocardiogram ECMO Endotracheal intubation extracorporeal membrane oxygenation Factor Fever FIVE gestational diabete hospital Ill information Intensive intensive care Invasive mechanical ventilation Karolinska University Hospital notable outcome Oxygen therapy Patient positive pregnant Pregnant woman pregnant women prolonged intensive care resulting retrospective SARS-CoV-2 Sery Severe respiratory distress still hospitalized Symptom Symptoms syndrome tested the patient treated Treatment was performed women [DOI] 10.1155/2021/8868822 PMC 바로가기 [Article Type] Case Series
Epidemiologic trends and characteristics of SARS-CoV-2 infections among children in the United States미국 어린이의 SARS-CoV-2 감염 역학 동향 및 특성Review Published on 2021-02-012022-09-11 Journal: Current opinion in pediatrics [Category] 치료기술, [키워드] Active surveillance acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition age Asymptomatic Characteristics children clinical feature Clinical features clinical manifestation clinical manifestations Complication complications contribute coronavirus death epidemiological Frequency highest Hospitalization illnesses incidence Infant Infants Infection less majority Mild nonspecific Older pandemic pediatric recent renal reported Research respiratory respiratory distress SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 pandemic severe acute respiratory syndrome Coronavirus severe disease Severe respiratory distress Symptom symptomatic infection the SARS-CoV-2 the United State The United States United States [DOI] 10.1097/MOP.0000000000000971 PMC 바로가기 [Article Type] Review
Cytokines and Chemokines in SARS-CoV-2 Infections—Therapeutic Strategies Targeting Cytokine StormReview Published on 2021-01-122022-10-28 Journal: Biomolecules [Category] COVID-19, [키워드] acute respiratory syndrome chemokine chemokines clinical development consequence Consequences coronavirus coronavirus disease COVID-19 COVID-19 infection COVID-19 infections CRS cytokine Cytokine release syndrome Cytokine storm Effects Factor hallmark host response Hyperinflammatory Infection pandemic pathophysiological Pneumonia progression SARS-CoV-2 selected Severe respiratory distress storm Strategy syndrome targeting Treatment upregulated virus [DOI] 10.3390/biom11010091 PMC 바로가기 [Article Type] Review