Remdesivir for the treatment of patients hospitalized with COVID-19 receiving supplemental oxygen: a targeted literature review and meta-analysis산소 보충을 받고 있는 COVID-19로 입원한 환자의 치료를 위한 렘데시비르: 표적 문헌 검토 및 메타 분석Review Published on 2022-06-102022-09-11 Journal: Scientific Reports [Category] 임상, 치료법, [키워드] baseline Controlled trial controlled trials credible interval CrI Efficacy HFO High-flow oxygen hospitalized patient hospitalized patients IMPROVE Improved literature review low-flow oxygen Meta-analysis Mortality need for oxygen Network meta-analysis NIV NMA NMAs Non-invasive non-invasive ventilation oxygen oxygen support Patient patients patients hospitalized performed receiving Remdesivir requiring supplemental oxygen risk risk ratio subgroups supplemental oxygen Support supportive care Treatment with COVID-19 [DOI] 10.1038/s41598-022-13680-6 PMC 바로가기 [Article Type] Review
Cardiopulmonary predictors of mortality in patients with COVID-19: What are the findings?Research article Published on 2022-06-012022-10-05 Journal: Archives of cardiovascular diseases [Category] COVID19(2023년), SARS, 바이오마커, [키워드] 95% CI 95% confidence interval association cardiac injury Characteristics clinical collected Computed tomography Concentration consecutive patient coronavirus disease COVID-19 CT score Deceased determine Electrocardiography groups haematological malignancy identify independent predictor initial Injury Kaplan-Meier analysis Laboratory Mortality mortality rate Odds ratio Patient patients with COVID-19 predictor pulmonary disease Result severity significantly shorter ST depression subgroups survival troponin was performed with COVID-19 [DOI] 10.1016/j.acvd.2022.04.008 [Article Type] Research article
Advanced Liver Fibrosis Correlates With Impaired Efficacy of Pfizer-BioNTech COVID-19 Vaccine in Medical Employees진행성 간 섬유증은 의료진에서 화이자-바이오엔텍 코로나19 백신의 효능 저하와 상관관계가 있습니다Article Published on 2022-06-012022-09-12 Journal: Hepatology communications [Category] MERS, 진단, [키워드] acute respiratory syndrome age booster calculated candidate center chronic liver disease coronavirus coronavirus disease correlated COVID-19 COVID-19 vaccine displaying Efficacy employee Factor FIB-4 fibrosis Fibrosis-4 Gender General population hepatic fibrosis IgG IgG level IgG titer Immunoglobulin Immunosuppressed Impaired Increased individual Jerusalem male males offered Older age Pfizer-BioNTech provide Responder risk factor significantly subgroups Undetermined vaccination Vaccine Vaccine failure vaccine response weakened [DOI] 10.1002/hep4.1901 PMC 바로가기 [Article Type] Article
Risk of Death in Comorbidity Subgroups of Hospitalized COVID-19 Patients Inferred by Routine Laboratory Markers of Systemic Inflammation on Admission: A Retrospective Study입원 시 전신 염증의 일상적인 실험실 지표에 의해 추론된 입원한 COVID-19 환자의 동반 질환 하위 그룹의 사망 위험: 후향적 연구Article Published on 2022-05-312022-09-11 Journal: Viruses [Category] MERS, 바이오마커, [키워드] Admission Analysis AUC Cluster cluster analysis Comorbidities Comorbidity confounding factor confounding factors correlation correlations COVID-19 COVID-19 mortality COVID-19 patients disease severity Factor hierarchical cluster analysis hospitalized COVID-19 patients Inflammatory inflammatory markers Laboratory laboratory parameter lymphocyte marker Model Mortality mortality risk neutrophil Neutrophil-to-lymphocyte ratio NLR on admission parameter Platelet positive positive correlations predict predictors recorded Regression model risk risk of death ROC Curve routine severity severity predictors. shown SII single-center study subgroup subgroups systemic systemic immune-inflammation index systemic inflammation WBC [DOI] 10.3390/v14061201 PMC 바로가기 [Article Type] Article
Risky health behaviors during the COVID-19 pandemic: Evidence from the expenditures on alcohol, non-alcoholic beverages, and tobacco productsObservational Study Published on 2022-05-192022-10-04 Journal: PLoS ONE [Category] 임상, [키워드] age alcohol Bi-weekly Characteristics concerning consumer COVID-19 COVID-19 pandemic diary Expenditure females Health health condition household individual information less Linear regression Mental pandemic predictor significantly Stress subgroups survey [DOI] 10.1371/journal.pone.0268068 PMC 바로가기 [Article Type] Observational Study
A large-scale meta-analytic atlas of mental health problems prevalence during the COVID-19 early pandemicCOVID-19 초기 전염병 동안 정신 건강 문제 유병률에 대한 대규모 메타 분석 지도Meta-Analysis Published on 2022-05-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 치료기술, [키워드] affected age Analysis Anxiety conducted country COVID-19 COVID-19 infection COVID-19 infection status COVID-19 pandemic Cross-sectional studies database Depression female followed by General population Health Organization healthcare healthcare worker Healthcare workers highest ideation Impact Infection Intervention median Mental disorder Mental Disorders mental health mental health burden mental health problem mental health problems Meta-analysis mitigate observational studies observational study outcome pandemic people with COVID-19 Prevalence prevalent Primary outcomes problem problems Sensitivity analyses Sex somatic disorder somatic disorders stratified Stress Subgroup analyses subgroup analysis subgroups Suicidal ideation Symptom Symptoms systematic review unique World Health Organization [DOI] 10.1002/jmv.27549 PMC 바로가기 [Article Type] Meta-Analysis
The humoral response to SARS-COV-2 vaccines in MS patients: A case series exploring the impact of DMT, lymphocyte count, immunoglobulins, and vaccine type다발성경화증 환자에서 SARS-COV-2 백신에 대한 체액성 반응: DMT, 림프구 수, 면역글로불린 및 백신 유형의 영향을 탐구하는 사례 시리즈Article Published on 2022-05-012022-09-11 Journal: Multiple sclerosis and related disorders [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] Affect age antibody association B-cell case sery CD19 Cell Certain disease correlation COVID19 depleting detectable disease disease phenotype disorder DMT dose Exploratory analysis females fumarate Gender group humoral Humoral response Hypogammaglobulinemia immune response immunoglobulins immunological immunological characteristics lymphocyte Lymphocyte count lymphocyte counts lymphopenia Mild Multiple multiple sclerosis no differences Patient performed positive positive patient positive patients Quantitative response to vaccination SARS-CoV-2 vaccine SARS-CoV-2 vaccines SARS-CoV2 seroconversion rate seroconversion rates Spike protein subgroup subgroups tested the spike protein therapy vaccination Vaccine vaccine response Vaccines variable verification [DOI] 10.1016/j.msard.2022.103785 PMC 바로가기 [Article Type] Article
Ruxolitinib in addition to standard of care for the treatment of patients admitted to hospital with COVID-19 (RUXCOVID): a randomised, double-blind, placebo-controlled, phase 3 trialResearch article Published on 2022-05-012022-10-05 Journal: The Lancet Rheumatology [Category] 임상, 치료법, [키워드] 95% CI acute respiratory distress addition Adverse age analysed assigned baseline benefit clinical status composite endpoint Concentration covariates COVID-19 Cytokine dysregulation Cytokine release syndrome death determine diarrhoea died disease disorder double-blind Efficacy event Exploratory analysis faster female finding funding hazard ratio headache hospital hospitalised ICU care Incyte Inflammatory cytokine inhibitor intensive care International invasive ventilation JAK1/JAK2 inhibitor Janus kinase Logistic regression male median time myelofibrosis nine Novartis occurred Odds ratio on mechanical ventilation Patient patients patients with COVID-19 per day phase 3 trial Placebo placebo-controlled primary endpoint randomised Randomly reduce Registered required Respiratory failure ruxolitinib secondary hemophagocytic lymphohistiocytosis Sex Standard of care study population subgroups the mean Treatment Trial with COVID-19 [DOI] 10.1016/S2665-9913(22)00044-3 [Article Type] Research article
Household transmission of SARS-CoV-2 from unvaccinated asymptomatic and symptomatic household members with confirmed SARS-CoV-2 infection: an antibody-surveillance studySARS-CoV-2 감염이 확인된 백신 접종을 하지 않은 무증상 및 증상이 있는 가구 구성원으로부터 SARS-CoV-2의 가구 전파: 항체 감시 연구Article Published on 2022-04-122022-09-11 Journal: CMAJ open [Category] COVID19(2023년), SARS, 진단, 치료법, [키워드] 95% CI 95% confidence interval Adults age Antibody testing Asymptomatic attack rate bedroom Chain Reaction Child children Clustering conducted contribute COVID-19 COVID-19 pandemic defined Descriptive statistics eligible eligible participant emergency department enrolled enrolment enzyme enzyme-linked immunosorbent assay enzyme-linked immunosorbent assays evaluate Health policy household household contact household contacts household transmission Households IgA IgM and IgG individual media multivariable logistic regression nucleocapsid protein number of household Odds ratio outcome participant Participation Patient performed polymerase chain polymerase chain reaction positive positive result predictor Primary outcome proportion public health required reverse transcription robust SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 antibody testing SARS-CoV-2 transmission secondary attack rate Spread standard error study participation study period subgroups symptomatic symptomatic and asymptomatic tested Transmission transmission of SARS-CoV-2 transmitted were used [DOI] 10.9778/cmajo.20220026 PMC 바로가기 [Article Type] Article
Severe Acute Respiratory Syndrome Coronavirus 2 Cumulative Incidence, United States, August 2020-December 2020중증 급성 호흡기 증후군 코로나바이러스 2 누적 발생률, 미국, 2020년 8월-2020년 12월Article Published on 2022-04-092022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] COVID19(2023년), SARS, 진단, 치료기술, 치료법, [키워드] accounted acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adjusted Adults antibody antibody waning Antigen antigen capture assay black Blood calculated can not conducted coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pandemic credible interval CrI cumulative cumulative incidence difference differential diagnosis disparity Emergency use fatality fraction IFR IgG IgM Immunoglobulin incidence infected with SARS-CoV-2 Infection infections nasal swab nasal swabs National nucleocapsid Probability probability survey provided public health random Random sample reported Reporting respiratory responses SARS-CoV-2 serology seropositive Seropositivity Severe acute respiratory syndrome specimen subgroup subgroups United States Viral Viral detection white [DOI] 10.1093/cid/ciab626 PMC 바로가기 [Article Type] Article