Patient-centered outcomes at hospital discharge in mechanically ventilated COVID-19 patients in Kobe, Japan: A single-center retrospective cohort studyResearch article Published on 2022-09-012022-10-05 Journal: Respiratory investigation [Category] 변종, [키워드] Activities of Daily Living adult COVID-19 patient clinical clinically Comorbidity conducted coronavirus disease COVID-19 COVID-19 infection COVID-19 patient Critical care demonstrated died discharge Dyspnea functional hospital discharge Hospitalization ICU in-hospital mortality independent intensive care interquartile range invasive Japan Kobe mechanical ventilation mechanically ventilated median age on mechanical ventilation organ dysfunction organ function outcome Patient receiving required Respiratory Support respiratory symptoms Result retrospective cohort study Retrospective study single-center survived survivor Survivors the patient was related [DOI] 10.1016/j.resinv.2022.06.010 [Article Type] Research article
Durable functional limitation in patients with coronavirus disease-2019 admitted to intensive care and the effect of intermediate-dose vs standard-dose anticoagulation on functional outcomesRandomized Controlled Trial Published on 2022-09-012022-10-05 Journal: European journal of internal medicine [Category] COVID19(2023년), SARS, 임상, [키워드] affected airway anticoagulation clinical trial coronavirus coronavirus disease COVID-19 depressive symptom Depressive symptoms disease Exercise limitation Follow-up form functional Health Hospitalization ICU ICU patient impair IMPROVE intensive care intermediate limitation mental health multiple organ failure Odds ratio outcome outcomes participated Patient Patient health questionnaire-2 patients died patients with COVID-19 PHQ-2 Prophylactic prophylactic anticoagulation proportion Randomized Randomized controlled trial randomized patient Standard-dose Survivors The post-COVID-19 functional status scale. trial participants with COVID-19 women [DOI] 10.1016/j.ejim.2022.06.014 PMC 바로가기 [Article Type] Randomized Controlled Trial
Harvest for Health, a Randomized Controlled Trial Testing a Home-Based, Vegetable Gardening Intervention Among Older Cancer Survivors Across Alabama: An Analysis of Accrual and Modifications Made in Intervention Delivery and Assessment During COVID-19Research article Published on 2022-09-012022-10-05 Journal: Journal of the Academy of Nutrition and Dietetics [Category] 임상, [키워드] Analysis anticipated approach assessment assigned Baseline assessment Breast cancer Cancer Controlled COVID-19 COVID-19 pandemic cross-over delivery diet dissemination Effect eligible enrolled Enrollment Evidence female functional gardening Harvest Health IMPROVE indicated Intervention Modification not differ objective Older Older adults outcome outcome measure participant performed physical physical activity Physical function populations primary end point protocol Quality of life Randomized Randomized controlled trial Randomly RCT recruited recruitment reported Result screened significantly higher survival survivor Survivors survivorship T Test Testing Trial vegetable were used widespread [DOI] 10.1016/j.jand.2022.05.005 [Article Type] Research article
SARS-CoV-2 vaccine-induced antibody and T cell response in SARS-CoV-1 survivorsArticle Published on 2022-08-302022-11-15 Journal: Cell Reports [Category] SARS, 변종, 진단, [키워드] acute respiratory syndrome antibody boost comparable coronavirus disease Coronavirus-2 CP: Immunology cross-reactive elicit healthy individual Immunity immunized induce memory T cells neutralization Neutralizing neutralizing antibody omicron robust SARS-CoV-1 SARS-CoV-1 survivors SARS-CoV-2 SARS-CoV-2 variant serum sample single dose survivor Survivors T cell response T cells the antibody response vaccination Vaccine variants of concern [DOI] 10.1016/j.celrep.2022.111284 PMC 바로가기
Impact of COVID-19 vaccination on the risk of developing long-COVID and on existing long-COVID symptoms: A systematic reviewResearch article Published on 2022-08-272022-10-05 Journal: EClinicalMedicine [Category] 바이오마커, [키워드] acute SARS-CoV-2 infection article association assumption case-controls changes in CINAHL Cohort studies collected COVID-19 COVID-19 vaccination decrease dose effective Evidence finding funding Impact individuals investigated long-COVID Long-COVID symptoms Methodological quality peer-reviewed study post-COVID syndrome Prevalence reduce reduced risk reported risk SARS-CoV-2 SARS-COV-2 infection searched subsequent supported Survivors Symptom systematic review the Newcastle-Ottawa Scale vaccination Vaccine vaccine administration Web of Science worsening [DOI] 10.1016/j.eclinm.2022.101624 [Article Type] Research article
Optimal Timing of Remdesivir Initiation in Hospitalized Patients With Coronavirus Disease 2019 (COVID-19) Administered With Dexamethasone덱사메타손을 투여한 2019 코로나바이러스 질환(COVID-19) 입원 환자에서 렘데시비르 시작의 최적 시기Article Published on 2022-08-242022-09-12 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 진단, [키워드] 95% CI acute respiratory distress addition applied benefit Clinical improvement Cohort coronavirus disease COVID-19 Cox regression models cumulative Dexamethasone difference drug exposure group Follow-up group hazard ratio Hong Kong hospital Hospital stay Hospitalization Hospitalized HRs IgG antibody In-hospital death increased risk initiated Initiation Length of hospital stay lower risk Multiple outcome Patient patients with moderate positive Probability progression Remdesivir significantly shorter Survivors syndrome time time to clinical improvement. Treatment Weighting were given WHO [DOI] 10.1093/cid/ciab728 PMC 바로가기 [Article Type] Article
SARS-CoV-2-reactive IFN-γ-producing CD4 + and CD8 + T cells in blood do not correlate with clinical severity in unvaccinated critically ill COVID-19 patients혈액 내 SARS-CoV-2 반응성 IFN-γ 생성 CD4 + 및 CD8 + T 세포는 백신 접종을 받지 않은 중환자 COVID-19 환자의 임상 중증도와 상관관계가 없습니다Article Published on 2022-08-222022-09-11 Journal: Scientific Reports [Category] SARS, 바이오마커, 진단, 치료기술, 치료법, [키워드] anti-RBD Anti-RBD IgG association Biomarker Biomarkers Blood blood levels C-reactive protein CD4 CD8 Clinical outcome Clinical severity comparable Concentration correlation COVID-19 patient COVID-19 patients Critically ill critically ill COVID-19 patients D-dimer Deceased detectable died different time point different time points ELISA Enumeration enzyme enzyme-linked immunosorbent assay examined ferritin flow cytometry greater magnitude IFN-γ IgG level increased mortality interleukin interleukin-6 investigated Kinetics Lactose Lower respiratory tract male median age membrane protein Mortality no correlation Patient patients Peripheral blood predict respiratory RNA loads SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 S sera Serum level serum levels specimens spike Spike protein survived Survivors T cell T cell subset T cells T-cell T-cell Response T-cell responses tracheal aspirate Viral viral clearance [DOI] 10.1038/s41598-022-18659-x PMC 바로가기 [Article Type] Article
The Associations of Iron Related Biomarkers with Risk, Clinical Severity and Mortality in SARS-CoV-2 Patients: A Meta-AnalysisSARS-CoV-2 환자의 위험, 임상 중증도 및 사망률과 철분 관련 바이오마커의 연관성: 메타 분석Review Published on 2022-08-192022-09-11 Journal: Nutrients [Category] SARS, 바이오마커, 치료기술, [키워드] 95% confidence interval acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition article Biomarker calculation caused clinical coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 progression deaths disease Diseases eligible evaluate Evidence ferritin ferritin level ferritin levels hemoglobin heterogeneity indicate Infection iron Iron metabolism magnitude mean difference Meta-analysis metabolism Mortality non-survivor Non-survivors Occurrence opposite Patient peer-reviewed Previous studies previous study progression random effect respiratory risk SARS-CoV-2 searched serum severe acute respiratory syndrome Coronavirus severity significantly lower SMD Survivors the disease TIBC was used Web of Science with COVID-19 [DOI] 10.3390/nu14163406 PMC 바로가기 [Article Type] Review
Prognostic impacts of soluble immune checkpoint regulators and cytokines in patients with SARS-CoV-2 infectionArticle Published on 2022-08-152022-11-15 Journal: Frontiers in Immunology [Category] SARS, 바이오마커, [키워드] Absolute lymphocyte count acute respiratory syndrome Bio-Plex 200 system C-reactive protein (CRP CCL2 chemokine Clinical practice Cluster coronavirus Coronavirus disease 2019 correlated correlation COVID-19 Critical cytokine cytokine level cytokine release Cytokine release syndrome death deaths diagnosed with COVID-19 different time point evaluated examined Factor GM-CSF IL-10 IL-8 immune immune checkpoint Immunoglobulin Impact Increased Infection inflammatory markers involved Laboratory Ligand marker motif multiplexed immunoassay nine pandemic Patient patients with SARS-CoV-2 performed Platelet poor prognosis positive correlation procalcitonin Prognosis prognostic Protein Quantitative SARS-CoV-2 SARS-CoV-2-infected patients serum sample shown significantly higher Stratification survivor Survivors T-cell virus entry were measured [DOI] 10.3389/fimmu.2022.903419 PMC 바로가기
Long-term cardiovascular outcomes in COVID-19 survivors among non-vaccinated population: A retrospective cohort study from the TriNetX US collaborative networksResearch article Published on 2022-08-112022-10-05 Journal: EClinicalMedicine [Category] 치료기술, [키워드] age Analysis arrhythmia Atrial fibrillation calculated cardiac disorders Cardiomyopathy cardiovascular disease Cardiovascular health Cardiovascular outcomes cerebrovascular diseases CIs Cohort conducted confidence controls COVID-19 COVID-19 test disease disorder disorders Elite endpoints female finding Follow-up Fund funding hazard heart failure Hospitalization HRs increased risk Infection Inflammatory initiated Inpatient interval male Mortality myocarditis network Non-COVID-19 outcome outcomes outpatients participant Patient performed Post-acute sequelae Probability Program public welfare recruited Research retrospective cohort study risk SARS-COV-2 infection SARS-CoV-2 testing scientist severity of COVID-19 Sex stratified stroke subgroup analysis survival survivor Survivors thromboembolic TriNetX two group [DOI] 10.1016/j.eclinm.2022.101619 [Article Type] Research article