Evaluating Upadacitinib in the Treatment of Moderate-to-Severe Active Ulcerative Colitis: Design, Development, and Potential Position in TherapyReview Published on 2022-06-172024-09-04 Journal: Drug design, development and therapy [Category] 대상포진, [키워드] Inflammatory bowel disease JAK1 inhibitor small molecule ulcerative colitis Upadacitinib [DOI] 10.2147/DDDT.S340459 PMC 바로가기 [Article Type] Review
A phase 3 randomized, multicenter, double-blind study to evaluate the safety of upadacitinib in combination with topical corticosteroids in adolescent and adult patients with moderate-to-severe atopic dermatitis in Japan (Rising Up): An interim 24-week analysisOriginal Article Published on 2021-12-202024-09-04 Journal: JAAD International [Category] 대상포진, [키워드] AD, atopic dermatitis AE, adverse event AESI, adverse event of special interest atopic dermatitis clinical trial CPK, creatine phosphokinase EASI 50, ≥50% improvement in eczema area and severity index EASI 75, ≥75% improvement in Eczema Area and Severity Index EASI 90, ≥90% improvement in Eczema Area and Severity Index EASI, Eczema Area and Severity Index eczema JAK, Janus kinase Janus kinase inhibitors SAE, serious adverse event Safety TCS, topical corticosteroid TEAE, treatment-emergent adverse event Topical corticosteroids Upadacitinib vIGA-AD, validated Investigator's Global Assessment for Atopic Dermatitis [DOI] 10.1016/j.jdin.2021.11.001 PMC 바로가기 [Article Type] Original Article
Systematic Review on the Efficacy and Safety of Oral Janus Kinase Inhibitors for the Treatment of Atopic Dermatitisarticle Published on 2021-09-012024-09-02 Journal: Frontiers in Medicine [Category] 대상포진, [키워드] abrocitinib atopic dermatitis Baricitinib eczema gusacitinib JAK inhibitor Janus kinase Upadacitinib [DOI] 10.3389/fmed.2021.682547 PMC 바로가기 [Article Type] article
Early phase studies of JAK1 selective inhibitors in rheumatoid arthritisSupplement Published on 2021-05-052024-09-04 Journal: Rheumatology (Oxford, England) [Category] 대상포진, [키워드] filgotinib itacitinib Janus kinase inhibitors rheumatoid arthritis Treatment Upadacitinib [DOI] 10.1093/rheumatology/keaa893 PMC 바로가기 [Article Type] Supplement
Clinical use of Jak 1 inhibitors for rheumatoid arthritisSupplement Papers Published on 2021-05-052024-09-04 Journal: Rheumatology (Oxford, England) [Category] 대상포진, [키워드] Efficacy filgotinib Jak 1 selectivity Safety Upadacitinib [DOI] 10.1093/rheumatology/keab265 PMC 바로가기 [Article Type] Supplement Papers
Effect of janus kinase inhibitors and methotrexate combination on malignancy in patients with rheumatoid arthritis: a systematic review and meta-analysis of randomized controlled trialsReview Published on 2021-04-282024-09-02 Journal: Autoimmunity Highlights [Category] 대상포진, [키워드] Baricitinib Decernotinib filgotinib jak inhibitors methotrexate Peficitinib rheumatoid arthritis Tofacitinib Upadacitinib [DOI] 10.1186/s13317-021-00153-5 PMC 바로가기 [Article Type] Review
Efficacy and safety of upadacitinib over 84 weeks in Japanese patients with rheumatoid arthritis (SELECT-SUNRISE)Research Article Published on 2021-01-062024-09-02 Journal: Arthritis Research & Therapy [Category] 대상포진, [키워드] Janus kinase inhibitor Japanese rheumatoid arthritis Upadacitinib [DOI] 10.1186/s13075-020-02387-6 PMC 바로가기 [Article Type] Research Article
Efficacy and safety of upadacitinib in Japanese patients with rheumatoid arthritis (SELECT-SUNRISE): a placebo-controlled phase IIb/III studyClinical Science Published on 2020-11-112024-09-04 Journal: Rheumatology (Oxford, England) [Category] 대상포진, [키워드] Efficacy Janus kinase inhibitor Japanese rheumatoid arthritis Safety Upadacitinib [DOI] 10.1093/rheumatology/keaa084 PMC 바로가기 [Article Type] Clinical Science
The new entries in the therapeutic armamentarium: The small molecule JAK inhibitorsArticle Published on 2019-09-012024-09-02 Journal: Pharmacological research [Category] 대상포진, [키워드] Baricitinib jak inhibitors rheumatic disease Tofacitinib Upadacitinib [DOI] 10.1016/j.phrs.2019.104392 PMC 바로가기 [Article Type] Article