SARS-CoV-2 reliably detected in frozen saliva samples stored up to one yearSARS-CoV-2는 최대 1년 동안 보관된 냉동 타액 샘플에서 안정적으로 검출됨Article Published on 2022-08-112022-09-11 Journal: PLoS ONE [Category] SARS, 치료기술, [키워드] Antigen COVID-19 pandemic Cycle threshold values Quantitative reported Research residual RT-PCR Saliva saliva samples SARS-CoV-2 storage surveillance testing university student Validity viability [DOI] 10.1371/journal.pone.0272971 PMC 바로가기 [Article Type] Article
Developing a Long COVID Phenotype for Postacute COVID-19 in a National Primary Care Sentinel Cohort: Observational Retrospective Database AnalysisObservational Study Published on 2022-08-112022-10-04 Journal: JMIR Public Health and Surveillance [Category] 임상, [키워드] 95% CI acute COVID-19 acute infection addition biomedical ontologies BioPortal Clinical characteristics clinical symptom clinically coded coding college Comorbidities complex computerized contribute COVID COVID-19 data accuracy data extracts data sets database develop Developing diagnosed Diagnosis Digital tool disease disease management Electronic health record English Epidemiology Ethnicity general practitioner General practitioners groups had no Health Hospital admission Hospitalization Hospitalized include individual Infection Laboratory Logistic regression Long Long COVID long-COVID management medical record systems nomenclature office ontological Ontology Oxford Patient phenotype postacute COVID-19 syndrome primary care problems public health RCGP recorded recruited Research retrospective RSC SARS-CoV-2 sentinel social class Sociodemographic Study protocol Surveillance Symptom Systematized Nomenclature of Medicine used data Validity [DOI] 10.2196/36989 PMC 바로가기 [Article Type] Observational Study
Attractive targeted sugar bait phase III trials in Kenya, Mali, and Zambia케냐, 말리, 잠비아에서 매력적인 표적 설탕 미끼 3상 시험Clinical Trial Published on 2022-08-092022-09-11 Journal: Trials [Category] 말라리아, 임상, 치료제, [키워드] adaptive ARMS Attractive targeted sugar bait children Cluster cluster separation Cluster-randomized controlled trial Clusters Cohort Contamination Controlled trial core covariate covariates COVID-19 pandemic detect determine dinotefuran Effects External validity Follow-up Imbalance IMPROVE incidence include insecticidal insecticide interim analysis internal validity Intervention Kenya kill Longevity malaria morbidity mosquito density Open-label open-label design phase III trial Prevalence Primary outcome Primary outcomes randomization receive reduce reduction in reductions in Restricted resulting risk Sample size secondary outcome strength Structure sugar threat Transmission transmission pattern Trial Two-arm Validity Variation vector vector control vectors [DOI] 10.1186/s13063-022-06555-8 PMC 바로가기 [Article Type] Clinical Trial
A fast online questionnaire for screening mental illness symptoms during the COVID-19 pandemic Research Published on 2022-08-042022-10-05 Journal: Translational Psychiatry [Category] 치료법, [키워드] Analysis Anxiety applied caused characteristic Clinical practice COVID-19 COVID-19 pandemic criterion demonstrated Depression disorder Effect Efficiency evaluate explained Factor GLA healthy controls high correlation identify illness Mental mental health mental illness mental symptom Patient PCA Prevalence principal component analysis questionnaire reliability Research Result ROC Screen Symptom Symptoms Validity [DOI] 10.1038/s41398-022-02086-7 [Article Type] Research
Assessing and improving the validity of COVID-19 autopsy studies – A multicentre approach to establish essential standards for immunohistochemical and ultrastructural analysesResearch article Published on 2022-08-022022-10-05 Journal: EBioMedicine [Category] Coronavirus, SARS, 치료기술, [키워드] Alliance Analysis antibody approach Assessing Autopsy autopsy study available data Berlin cell line cellular structure center correlated COVID-19 criteria education Effect Effects electron microscopy evaluated finding foundation funding Guidance help high variability highest IHC immune response immunohistochemistry Interpretation Microscopy Ministry of Health multicentre organ organ damage pathology pathophysiology positive correlation Protein provided Quantitative recommendation reproducibility RT-qPCR SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 nucleocapsid SARS-CoV-2 viral RNA Sensitivity and specificity specificity the SARS-CoV-2 tissue tissues university Validity Variability Viral protein virus [DOI] 10.1016/j.ebiom.2022.104193 [Article Type] Research article
Concern about COVID-19 among the Spanish population: Validation of a scale and associated symptomsResearch article Published on 2022-08-012022-10-05 Journal: Journal of affective disorders [Category] COVID19(2023년), SARS, 진단, [키워드] Adults Analysis analyzed Anxiety anxiety disorders anxiety symptom caused changes in comparison concern construct validity Contagion coronavirus Covid patients COVID-19 COVID-19 outbreak COVID-19 pandemic COVID-19 patient cross-sectional design diagnosed General population Generalized anxiety disorder (GAD) Health incidence increase in limitation lockdown measure mental health service participant reliability Result Spain Spanish Spread Symptom the disease validation Validity viral disease [DOI] 10.1016/j.jad.2022.05.018 [Article Type] Research article
Knowledge, attitude, and practice towards COVID-19: Research to develop a measuring instrumentResearch article Published on 2022-08-012022-10-05 Journal: Atencion Primaria [Category] 변종, [키워드] alpha value Analysis applied approach Attitude Bursa can be used center CFA Cleanliness coefficients confirmatory factor analysis COVID-19 develop distance evaluate evaluated Factor Factor analysis family individual internal and external knowledge objective pandemic Pandemics participant performed Practice Quantitative question Research responses Result scale scoring system Site statistically significant status Turkey Turkey-scale Uludağ university Validity was obtained [DOI] 10.1016/j.aprim.2022.102370 [Article Type] Research article
De Novo design of potential inhibitors against SARS-CoV-2 MproSARS-CoV-2 Mpro에 대한 잠재적 억제제의 새로운 설계Article Published on 2022-08-012022-09-11 Journal: Computers in biology and medicine [Category] COVID19(2023년), SARS, 치료제, [키워드] binding can be used Complete composed compounds COVID-19 de novo de novo drug design. deep deep learning drug drug design evaluate evaluated filtered inhibitor inhibitory effect Inhibitory effects machine learning model machine learning models memory molecular docking molecular dynamics Molecular dynamics simulation molecular dynamics simulations MPro provide SARS-CoV-2 main protease SARS-CoV-2 Mpro stability transfer transfer learning Validity Virtual screening [DOI] 10.1016/j.compbiomed.2022.105728 PMC 바로가기 [Article Type] Article
Psychometric Properties of the Hospital Anxiety and Depression Scale (HADS) in Previously Hospitalized COVID-19 PatientsMulticenter Study Published on 2022-07-292023-07-10 Journal: International Journal of Environmental Research an [Category] COVID19(2023년), [키워드] COVID-19 Hospital Anxiety and Depression Scale Long COVID Validity [DOI] 10.3390/ijerph19159273 PMC 바로가기 [Article Type] Multicenter Study
Analysis of multi-strain infection of vaccinated and recovered population through epidemic model: Application to COVID-19전염병 모델을 통한 예방접종 및 회복된 인구의 다중 균주 감염 분석: COVID-19에 적용Article Published on 2022-07-292022-09-11 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 변종, [키워드] analyzed application assumed calculated condition COVID-19 COVID-19 virus Delta dissemination Endemic Epidemic greater herd immunity Herd immunity threshold immune Infection Infectious disease investigated multi Mutation omicron Omicron variants question Reproduction number Spread stability state strain Strains susceptible the disease Vaccine Validity variant variants viral strains [DOI] 10.1371/journal.pone.0271446 PMC 바로가기 [Article Type] Article