Predictors of Influenza Vaccination Uptake and the Role of Health Literacy among Health and Social Care Volunteers in the Province of Prato (Italy)Article Published on 2022-05-302023-07-09 Journal: International Journal of Environmental Research an [Category] COVID19(2023년), [키워드] COVID-19 Influenza Italy survey Vaccine volunteers [DOI] 10.3390/ijerph19116688 PMC 바로가기
A Third Dose of an Inactivated Vaccine Dramatically Increased the Levels and Decay Times of Anti-SARS-CoV-2 Antibodies, but Disappointingly Declined Again: A Prospective, Longitudinal, Cohort Study at 18 Serial Time Points Over 368 Days비활성화 백신의 세 번째 접종은 항 SARS-CoV-2 항체의 수준과 붕괴 시간을 극적으로 증가시켰지만 다시 실망스럽게 감소했습니다: 368일 동안 18개의 연속 시점에서 전향적, 종적, 코호트 연구Article Published on 2022-04-292022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] 95% CI activate administration anti-RBD anti-SARS-CoV-2 anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 antibody Anti-spike anti-Spike IgG antibody antibody levels booster dose carried conversion rate CoronaVac COVID-19 Day decay dose Efficacy evaluate FIVE fold half-life half-live half-lives IgA IgA level IgG IgM immune immune characteristics immune protection Immunity inactivated Increased Level longitudinal management much lower neutralizing antibody over Point positive positive conversion Predictive predictive values Prospective prospective cohort study regimen regimens remained response revaccination SARS-CoV-2 SARS-CoV-2 vaccine SARS-CoV-2 variants second dose subset the SARS-CoV-2 time vaccination Vaccine volunteers [DOI] 10.3389/fimmu.2022.876037 PMC 바로가기 [Article Type] Article
Longitudinal Randomized Cohort Study of SARS-CoV-2 Antibody Seroprevalence in the St. Petersburg Population상트페테르부르크 인구에서 SARS-CoV-2 항체 혈청유병성에 대한 종단 무작위 코호트 연구Randomized Controlled Trial Published on 2022-04-272022-09-11 Journal: Viruses [Category] COVID19(2023년), SARS, 임상, 진단, 치료기술, 치료법, [키워드] 95% CI Adults age anti-RBD antibodies antibody Antigen antigen receptor antigen receptor binding domain approved calculated calculator carried characteristic children Cohort conducted confidence Confidence intervals coronavirus coronavirus SARS-CoV-2 COVID-19 COVID-19 pandemic COVID-19 patient decrease died effort enzyme enzyme immunoassays FIVE form herd immunity Immunity immunoassays implementation increase in indicated interval less longitudinal material methodology nucleocapsid nucleocapsid antigen Older organized pandemic participated Participation Pasteur Institute percentage percentages Population proportion Quantitative Randomized RBD Receptor binding Receptor binding domain required Russia SARS-CoV-2 SARS-CoV-2 nucleocapsid seropositive Seropositivity Seroprevalence Seven significantly St. Petersburg Stage stages statistical significance statistically statistically significant vaccination Vaccine Vaccines Volunteer volunteers were assessed were recorded z-test [DOI] 10.3390/v14050913 PMC 바로가기 [Article Type] Randomized Controlled Trial
First computational design using lambda-superstrings and in vivo validation of SARS-CoV-2 vaccine Research Published on 2022-04-192022-10-05 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] acute respiratory syndrome Amino acid anti-viral response Asymptomatic Bacterial cellular coronavirus Coronavirus disease 2019 COVID-19 COVID-19 patients cytokine profile dendritic cell disease Donor effective Efficacy effort elicit elicited epitope experiment Health Human humoral immune responses immune response Immunity in vivo indicated introduced negative control NTD NTD domain pathogen peptide peptide-based vaccine performed positive control predominant Protein provided Receptor binding domain Research SARS-CoV-2 SARS-CoV-2 vaccine subjects tested the Spike the vaccine Vaccine vaccine candidate Vaccines Validity volunteers [DOI] 10.1038/s41598-022-09615-w [Article Type] Research
Assessment of T-cell Reactivity to the SARS-CoV-2 Omicron Variant by Immunized Individuals면역화된 개인에 의한 SARS-CoV-2 오미크론 변이체에 대한 T 세포 반응성 평가Article Published on 2022-04-012022-09-11 Journal: JAMA Network Open [Category] COVID19(2023년), SARS, 변종, [키워드] age assessment blood sample Blood samples Care CD4+ cell CD4+ cells CD4+ T cell CD4+ T cells CD8+ T cells Cell cellular component cellular immunity cohort study conducted contagious decrease determine enrolled foundation Frequency full-length protein group Health Health care highlight Hospitalization immune immune protection immune system Immunity immunized individual Infection Italy Lymphocytes median mutated Mutation Neutralizing new SARS-CoV-2 no significant differences omicron Omicron variant outcome participant peptide peptides reactive reactivity reduced reduction Region regions Rome SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 variant sera severe disease significant difference significantly Spike protein Stimulation T cells T-cell T-cell immunity tested the SARS-CoV-2 the spike protein vaccination variant variant of SARS-CoV-2 Volunteer volunteers women [DOI] 10.1001/jamanetworkopen.2022.10871 PMC 바로가기 [Article Type] Article
Dynamic observation of SARS-CoV-2 IgM, IgG, and neutralizing antibodies in the development of population immunity through COVID-19 vaccinationSARS-CoV-2 IgM, IgG, 중화항체의 코로나19 예방접종을 통한 집단면역 발달의 동적 관찰Article Published on 2022-04-012022-09-11 Journal: Journal of Clinical Laboratory Analysis [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] antibody Antibody responses assays assessment booster dose booster vaccination changes in chemiluminescent immunoassay CLIA convalescent Conventional conventional virus neutralization test coronavirus coronavirus disease coronavirus disease-2019 correlation COVID-19 COVID-19 convalescent COVID-19 vaccination COVID-19 vaccine criterion cVNT diagnostic discharge dynamic ELISAs enzyme-linked immunosorbent assay enzyme-linked immunosorbent assays evaluated FIVE foundation guide humoral immune response IgG IgM immune immune response Immunity include indicated individual NAb assay NAbs neutralization test Neutralizing neutralizing antibody observation Patient population immunity positive rate ranged Rapid reached receipt SARS-CoV-2 IgM SARS-COV-2 infection second dose Sensitivity and specificity serological seropositivities Seropositivity serum Serum neutralizing antibody specific IgM the antibody response vaccination Vaccine virus neutralization test Volunteer volunteers was used [DOI] 10.1002/jcla.24325 PMC 바로가기 [Article Type] Article
Evaluation of antibody response after COVID-19 vaccination of healthcare workers의료진의 코로나19 예방접종 후 항체반응 평가Article Published on 2022-03-012022-09-11 Journal: Journal of medical virology [Category] MERS, SARS, 진단, 치료법, [키워드] addition age antibody antibody levels Antibody Response antibody response against Antibody titer Antibody titers BMI BMI values body mass body mass index CoronaVac COVID-19 COVID-19 vaccination develop dose effective Elecsy Elecsys evaluated examined Factor female Gender HCW healthcare healthcare worker Healthcare workers immune response Immunity Inactivated vaccine individuals infected with COVID-19 interquartile range IQR male median age nucleocapsid protein obese participant Participants participated postvaccination RBD RBD protein Receptor binding Receptor binding domain Receptor-binding domain SARS-CoV-2 SARS-CoV-2 spike protein second dose second dose of vaccine Seropositivity Smokers smoking Spike protein the receptor-binding domain the SARS-CoV-2 U/mL Vaccine Volunteer volunteers was determined was measured [DOI] 10.1002/jmv.27420 PMC 바로가기 [Article Type] Article
Detection and Contact Tracing of COVID-19 in Indonesia through a Red Cross Community Based Surveillance SystemConference abstract Published on 2022-03-012022-10-05 Journal: International Journal of Infectious Diseases [Category] 치료기술, [키워드] 24 hours Active surveillance approach CBS Community complement component Contact Contact tracing COVID-19 Critical detect detection Diagnosis disease effective eight event feasible Follow-up visit Health health authorities healthcare facility Human identify individual Indonesia Infectious disease Local local response management many cases material Pandemics PCR positive positive preventive measure public health Red reported Result scaled supported Surveillance System threat tracing undergo Volunteer volunteers [DOI] 10.1016/j.ijid.2021.12.085 [Article Type] Conference abstract
A phase I, first-in-human, randomized dose-escalation study of anti-activated factor XII monoclonal antibody garadacimab항 활성화 인자 XII 단일 클론 항체 garadacimab의 I 상, 최초 인간, 무작위 용량 증량 연구Clinical Trial Published on 2022-03-012022-09-12 Journal: Clinical and translational science [Category] MERS, 임상, 진단, [키워드] activated activities Analysis antibodies blood sample clinical development Coagulation Cohort cohorts collected Contact coronavirus disease COVID-19 deaths demonstrated dose dose-dependent dose-dependent manner dose-escalation Effect eight Factor healthy healthy volunteers increase in increases in inhibit intravenous male monoclonal antibody MOST pathway Phase I Placebo plasma plasma concentration positive proinflammatory Prothrombin time prothrombotic Randomized reported single-center Support TEAE TEAEs tested Tolerability treatment-emergent adverse event Volunteer volunteers [DOI] 10.1111/cts.13180 PMC 바로가기 [Article Type] Clinical Trial
Anti-CD20 monoclonal antibodies inhibit seropositive response to Covid-19 vaccination in non-Hodgkin lymphoma patients within 6 months after treatment항-CD20 단일클론항체는 치료 후 6개월 이내에 비호지킨 림프종 환자에서 Covid-19 예방접종에 대한 혈청양성 반응을 억제합니다Article Published on 2022-03-012022-09-12 Journal: Experimental hematology [Category] MERS, SARS, 진단, 치료법, [키워드] anti-CD20 anti-CD20 treatment B cell caused CD19 death Efficacy immunosuppressive indicated inhibit less lymphocyte lymphoma monoclonal antibodies monoclonal antibody Non-Hodgkin Lymphoma pandemic Patient Pfizer-BioNTech Prevent respond seropositive the healthy the vaccine therapy treated Treatment vaccination Vaccine volunteers [DOI] 10.1016/j.exphem.2021.12.396 PMC 바로가기 [Article Type] Article