G6PD deficiency and severity of COVID19 pneumonia and acute respiratory distress syndrome: tip of the iceberg?Original Article Published on 2021-01-132023-07-01 Journal: Annals of Hematology [Category] SARS, [키워드] African American COVID19 G6PD X-linked [DOI] 10.1007/s00277-021-04395-1 PMC 바로가기 [Article Type] Original Article
An overview of Betacoronaviruses-associated severe respiratory syndromes, focusing on sex-type-specific immune responsesReview Published on 2021-01-102022-11-01 Journal: International immunopharmacology [Category] COVID-19, MERS, [키워드] Abstract Activation acute respiratory illness Anti-viral approaches autoimmune reactions beta-coronavirus bi-allelic blood circulation coronavirus COVID-19 COVID19 disease epidemiological expression Fatality rate feature female females Frequency Genes Host immune response IFN immune Immune cell immune protection immune response immune responses immune system Immunotherapy inactive Infection infection rate information involved less male MERS MERS-CoV Middle East pathogen Regulatory respiratory respiratory infection responsible robust SARS SARS-CoV-1 SARS-CoV-2 similarity susceptibility susceptible the antibody TLR7 Treatment Vaccine development Variation viral infections Viral load X-linked β-CoVs [DOI] 10.1016/j.intimp.2021.107365 PMC 바로가기 [Article Type] Review
Magnesium in Infectious Diseases in Older PeopleReview Published on 2021-01-082022-10-31 Journal: Nutrients [Category] COVID-19, MERS, [키워드] Activation age aging association B cells Bacterial infection characterized chronic cofactor complications coronavirus disease COVID-19 cytosolic deficiency Diseases Epstein–Barr virus functional Genetic Immune cell immune response immune system Immunity immunodeficiency Immunoglobulin Infection Infectious disease Infectious diseases Inflammation key factor low-grade inflammation Magnesium MAGT1 oxidative stress pandemic of COVID-19 Pathogenesis predisposition receptor reduced Regulation renal Research Transport Vitamin D X-linked [DOI] 10.3390/nu13010180 PMC 바로가기 [Article Type] Review
Treatment of COVID-19 with remdesivir in the absence of humoral immunity: a case reportArticle Published on 2020-12-142022-10-04 Journal: Nature Communications [Category] MERS, SARS, 변종, 진단, 치료기술, 치료법, 치료제, [키워드] absence Activation acute respiratory syndrome antibody antiviral efficacy antiviral therapy antivirals approach benefit Case report Clinical course clinical trials complement confounders coronavirus coronavirus disease correlated Course COVID-19 deficiency drug resistance effective Evidence Genetic humoral in vivo independent lack observé over pandemic patient with COVID-19 patients Primary immunodeficiency disorders progression reduce Remdesivir robust SARS-CoV-2 SARS-CoV-2 replication selected severe disease T cell response the patient Treatment utility viral clearance viral infection virological response X-linked XLA [DOI] 10.1038/s41467-020-19761-2 PMC 바로가기 [Article Type] Article
Glucose-6-Phosphate Dehydrogenase Deficiency: An Actionable Risk Factor for Patients with COVID-19?Research article Published on 2020-10-012022-10-05 Journal: Archives of medical research [Category] SARS, 변종, [키워드] affected African Asian Asymptomatic coronavirus COVID-19 COVID-19 infection deficiency dehydrogenase drug drugs element Factor G6PD Genetic glucose-6-phosphate dehydrogenase Glucose-6-phosphate deydrogenase deficiency hemolytic anemia individual individuals Infection Latin Mutation outcome oxidative stress Patient populations prevalent risk factor treat viral infection X-linked [DOI] 10.1016/j.arcmed.2020.06.006 [Article Type] Research article
The Expression and Polymorphism of Entry Machinery for COVID-19 in Human: Juxtaposing Population Groups, Gender, and Different TissuesBrief Report Published on 2020-05-142022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, SARS, [키워드] ACE2 ACE2 receptor ACE2 variant American Analysis Asians booster change coding gene COVID-19 determinant factor Epidemic Europeans examined expressed expression females Frequency Gender gene expression profile group groups had no Host host entry machinery human ACE2 individual Infection kidney lack locus male males mortality rate MOST outbreak Personalized medicine polymorphism population groups public health rare variant required Result salivary gland SARS viruses SARS-CoV-2 significant difference small intestine supported tissue variant viral disease viral entry X-linked [DOI] 10.3390/ijerph17103433 PMC 바로가기 [Article Type] Brief Report
Xist RNA in action: Past, present, and future활동 중인 Xist RNA: 과거, 현재, 미래Review Published on 2019-09-192022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] affected chromatin chromosomal dosage embryonic embryonic development Epigenetic event female focus functional gene silencing genomic genomic imprinting inactivation initiate interaction partner knowledge long noncoding RNA male mammal mammals memory modifying factors multitude Perspective plethora recruit Research RNA Sex transcribed transcript Trigger triggers X chromosome X-linked Xist [DOI] 10.1371/journal.pgen.1008333 PMC 바로가기 [Article Type] Review
Loss of Xist RNA from the inactive X during B cell development is restored in a dynamic YY1-dependent two-step process in activated B cellsB 세포 발달 동안 비활성 X에서 Xist RNA의 손실은 활성화된 B 세포에서 동적 YY1 종속 2단계 과정으로 복원됩니다.Research Article Published on 2017-10-092022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] activated Activation adulthood Autoimmune disorders Autoimmunity B cell B cells Cell change chromatin chromosome compensated Critical develop DNA DNA binding domain dosage ectopic expression embryogenesis Epigenetic Ex vivo expression female Genes Genetic heterochromatin Immunity impair inactivation inactive indicate lack Lineage Loss lymphocyte Lymphocytes mechanism Modification modifications pathogenic pattern Recombination regulate regulated restored reveal RNA Stimulation susceptibility transcription factor up-regulation X-linked X-linked gene YY1 Zinc [DOI] 10.1371/journal.pgen.1007050 PMC 바로가기 [Article Type] Research Article
Comparative Transcriptomics of Malaria Mosquito Testes: Function, Evolution, and Linkage말라리아 모기 고환의 비교 전사체학: 기능, 진화 및 연관성Investigation Published on 2017-02-022024-08-12 Journal: G3: Genes|Genomes|Genetics [Category] 말라리아, [키워드] Anopheles demasculinization RNA sequencing X-linked [DOI] 10.1534/g3.117.040089 PMC 바로가기 [Article Type] Investigation
Chronic Granulomatous Disease A Large, Single-center US Experiencearticle Published on 2015-10-152024-09-02 Journal: The Pediatric Infectious Disease Journal [Category] 대상포진, [키워드] antimicrobial prophylaxis autosomal recessive Chronic granulomatous disease interferon-outcomes X-linked [DOI] 10.1097/INF.0000000000000840 PMC 바로가기 [Article Type] article