Combined Cardiac Risk Factors Predict COVID-19 Related Mortality and the Need for Mechanical Ventilation in Coptic ClergyArticle Published on 2021-05-122022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] adverse event Analysis cardiac cardiovascular risk factors CHD Clergy Combined Coptic clergy Coronary heart disease COVID-19 COVID-19 related mortality cumulative Europe Factor group hospital independent Infection intensive care management Mechanical mechanical ventilation Mortality mortality rate not differ obese obesity Older participant predicted risk factor SBP systemic arterial hypertension Systolic blood pressure the patient Treatment type 2 diabete USA were assessed [DOI] 10.3390/jcm10102066 PMC 바로가기 [Article Type] Article
Randomized controlled trial of convalescent plasma therapy against standard therapy in patients with severe COVID-19 disease중증 COVID-19 질환 환자의 표준 요법에 대한 회복기 혈장 요법의 무작위 대조 시험Randomized Controlled Trial Published on 2021-05-112022-08-13 Journal: Scientific Reports [Category] SARS, 임상, 치료기술, 치료법, [키워드] 95% CI appear biochemical parameter Biochemical parameters clinical Clinical outcome confirmation Control Controlled trial convalescent patient Convalescent plasma therapy COVID-19 disease COVID-19 patient CP group died feasibility ferritin ferritin level higher risk hospitalized COVID-19 patient hospitalized COVID-19 patients hypoxia IMPROVE measure mechanical ventilation Mortality NIV no difference no differences no significant difference no significant differences Non-invasive not differ one patient open open label Patient pilot study plasma Primary outcome primary outcome measure Randomized Randomized controlled trials required respiratory indice respiratory indices risk risk ratio Safe secondary outcome secondary outcome measure Secondary outcomes severe COVID-19 severe COVID-19 disease severe disease Standard of care Standard therapy therapy Trial Two patient two patients Ventilation Virology [DOI] 10.1038/s41598-021-89444-5 PMC 바로가기 [Article Type] Randomized Controlled Trial
Natural mucosal barriers and COVID-19 in children어린이의 자연 점막 장벽과 COVID-19Clinical Medicine Published on 2021-05-102022-09-10 Journal: JCI Insight [Category] SARS, 유전자 메커니즘, 진단, 치료기술, [키워드] Adults Albert Einstein angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 anti–SARS-CoV-2 IgG Award both groups cellular children clinical clinical outcomes college contribute coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Cytokines died disease manifestation emergency department enzyme epithelial cell epithelial cells Eric Evidence evidence of expressed expression expression of gene Gene Expression IFN signaling IFN-α2 IFN-γ IgA IgG IL-1β IL-8 immune cells Infectious disease innate immune response Innate immunity IP-10 Medicine mucosal mucosal immune nasal fluid Nasopharyngeal swab nasopharyngeal swabs natural NIH NLRP3 inflammasome not differ other respiratory virus Other respiratory viruses outcomes oxygen Pathways PROTECT Protein quantified quantitative reverse-transcription PCR required respiratory respiratory viruses RNA sequencing robust SARS Coronavirus SARS coronavirus 2 SARS-CoV-2 SARS-CoV-2 viral severe disease supplemental oxygen TMPRSS2 total protein Viral viruses [DOI] 10.1172/jci.insight.148694 PMC 바로가기 [Article Type] Clinical Medicine
Characterisation of asymptomatic patients and efficacy of preventive measures for SARS-CoV-2 infection in a large population of Southern Italy: a cohort study남부 이탈리아의 많은 인구에서 무증상 환자의 특성 및 SARS-CoV-2 감염 예방 조치의 효능: 코호트 연구Article Published on 2021-05-102022-09-11 Journal: BMJ Open [Category] SARS, 치료기술, [키워드] all subject all subjects approach Asymptomatic Asymptomatic carrier Asymptomatic carriers asymptomatic patient asymptomatic subjects caused close contact cohort study Combination Contact COVID-19 COVID-19 epidemic death decrease Efficacy Epidemic Epidemiology healthcare healthcare facility Healthcare workers hospital indicated infected with SARS-CoV-2 Infection International Isolation Italy limit measure MOST Nasopharyngeal swab not differ outbreak performed Phase 1 positive Prevalence preventive measure processed Real-time PCR retrospective cohort study SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 gene SARS-CoV-2 genes SARS-COV-2 infection SARS-CoV-2 pandemic social distancing specimen Spread subject subjects Symptom symptomatic symptomatic case symptomatic cases tested the epidemic the SARS-CoV-2 Virology virus transmission was performed [DOI] 10.1136/bmjopen-2020-043112 PMC 바로가기 [Article Type] Article
Epidemiological, Clinical, and Laboratory Features of Children With COVID-19 in TurkeyPediatrics Published on 2021-05-072022-10-31 Journal: Frontiers in Pediatrics [Category] COVID-19, [키워드] age Asthma Asymptomatic biochemical test Characteristics Chest computed tomography chest X-ray children clinical collected complete blood count conducted confirmed case Contact coronavirus disease cough COVID-19 COVID-19 cases diagnosed Diagnosis diarrhea discharge disease disease onset disease severity distribution Dyspnea epidemiological Epidemiology female Fever forms hospital Hospitalization identify Infectious disease information intensive care knowledge Laboratory laboratory feature laboratory findings Lung disease male median median age Mild moderate disease myalgia nasal not differ Older parameter Patient pediatric Retrospective study severe disease severity of symptoms Sex significant difference sore throat susceptible Symptom the patient Turkey underlying condition underlying disease were recorded [DOI] 10.3389/fped.2021.631547 PMC 바로가기 [Article Type] Pediatrics
The impact of SARS-COV2 infection on people in residential care with Parkinson Disease or parkinsonisms: Clinical case series studySARS-COV2 감염이 파킨슨병 또는 파킨슨증을 앓고 있는 주거 시설에 있는 사람들에게 미치는 영향: 임상 사례 시리즈 연구Case Reports Published on 2021-05-062022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 임상, 치료기술, [키워드] age Asymptomatic Care case sery chronic disease clinical clinical conditions Cohort comparable Computed tomography coronavirus coronavirus disease Course COVID-19 COVID-19 disease COVID-19 infection daily dose detect develop disease Epidemic evaluate Gender group Health Organization highlight Hospitalized Infection L-DOPA Laboratory tests limited sample size lung Mortality not differ observational study Occurrence other diseases outbreak outcome pandemic Parkinson’s disease Parkinsonism Patient performed Pharyngeal swab positive Primary outcome respiratory respiratory difficulties retrospective risk risk factor SARS-CoV2 SARS-CoV2 infection second Sex Stage subject susceptibility susceptible symptomatic tested the patient unit World Health Organization worsening [DOI] 10.1371/journal.pone.0251313 PMC 바로가기 [Article Type] Case Reports
Prevalence and clinical significance of antiphospholipid antibodies in patients with coronavirus disease 2019 admitted to intensive care units: a prospective observational study2019년 중환자실에 입원한 코로나바이러스 질환 환자에서 항인지질항체의 유병률 및 임상적 중요성: 전향적 관찰 연구Observational Study Published on 2021-05-052022-09-12 Journal: Rheumatology International [Category] SARS, 임상, 진단, [키워드] 95% confidence interval adjusted odds ratio Affect age all-cause mortality antibody Anticoagulant antiphospholipid antibodies arterial arterial or venous thrombosis Arterial thrombosis Asia Clinical significance clinically clinician Coagulopathy coronavirus disease Coronavirus disease 2019 COVID-19 Critically ill Critically ill patient critically ill patients enrolled evaluate ICU increase intensive care intensive care unit intensive care units Lupus lupus anticoagulant majority mechanism men Mortality multiple logistic regression not differ observational study Odds ratio one patient outcome p value Patient patients with COVID-19 positive Prevalence prospective observational study remains uncertain risk study outcome study outcomes thrombosis Venous thrombosis was used with COVID-19 [DOI] 10.1007/s00296-021-04875-7 PMC 바로가기 [Article Type] Observational Study
Guillain-Barre syndrome in 220 patients with COVID-19Review Published on 2021-05-042022-10-31 Journal: The Egyptian Journal of Neurology, Psychiatry and Neurosurgery [Category] COVID-19, [키워드] age concerning COVID-19 CSF Diagnosis Guillain-barrè syndrome immune reaction immunoglobulins IMPROVE Infection Nerve conduction not differ occur outbreak outcome pandemic pathophysiology Patient patients patients with COVID-19 recent finding reported SARS-CoV-2 Treatment virus [DOI] 10.1186/s41983-021-00310-7 PMC 바로가기 [Article Type] Review
Plasma LDH: A specific biomarker for lung affectation in COVID-19?Short communication Published on 2021-05-012022-10-05 Journal: Practical Laboratory Medicine [Category] 바이오마커, [키워드] activity Alanine albumin Analysis Aspartate aminotransferase Biomarker bloodstream C-reactive protein collected Control COVID-19 creatinine determine expected expressed ferritin fresh plasma lactate dehydrogenase LDH LDH isoenzymes lung Lungs Lymphocyte count no correlation not differ objective Patient patients with COVID-19 plasma reported Result SARS-CoV-2 serum parameter Seven Support was determined [DOI] 10.1016/j.plabm.2021.e00226 [Article Type] Short communication
Immunoglobin G/total antibody testing for SARS-CoV-2: A prospective cohort study of ambulatory patients and health care workers in two Belgian oncology units comparing three commercial testsSARS-CoV-2에 대한 면역글로불린 G/총 항체 검사: 3개의 상용 검사를 비교하는 2개의 벨기에 종양학 병동의 보행 환자 및 의료 종사자에 대한 전향적 코호트 연구Comparative Study Published on 2021-05-012022-09-12 Journal: European journal of cancer (Oxford, England : 1990 [Category] MERS, SARS, 진단, [키워드] Abbott absolute value added ambulatory patient antibody Antibody testing Antwerp Better Cancer cancer patient Cancer patients coronavirus 2 correlated COVID-19 Diagnosis DiaSorin disease First wave Fisher Ghent HCW Health care Health care worker health care workers healthy volunteers hematological high risk humoral immune response immune response Immunoglobulin G individual Infection knowledge management median much lower negative test not differ oncology pandemic participated Patient polymerase chain positive positive RT-PCR prospective cohort study rate of seroconversion remained respiratory Roche RT-PCR SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 antibody test SARS-CoV-2 IgG SARS-CoV-2 RT-PCR Seroconversion Seroprevalence significantly solid tumour study period study population the patient Treatment tumour unit university vaccination was measured were used [DOI] 10.1016/j.ejca.2021.02.024 PMC 바로가기 [Article Type] Comparative Study