A single-cell atlas of the peripheral immune response in patients with severe COVID-19
Research
[키워드] acute respiratory distress
appear
applied
caused
Cell
changes in
Coronavirus disease 2019
COVID-19
develop
disease
downregulation
global pandemic
healthy controls
heterogeneous
HLA class II
identify
immune
Immune cell
immunopathology
Inflammatory
Intensive
interferon-stimulated gene
lymphocyte
mechanical ventilation
monocyte
mononuclear cell
neutrophil
not express
pathophysiology
pathway
Patient
patients hospitalized
patients with COVID-19
PBMCs
Peripheral blood
peripheral immune response
phenotype
plasmablast
pro-inflammatory
pro-inflammatory cytokines
produced
protective immunity
Respiratory failure
SARS-CoV-2
scRNA-seq
Seven
severe COVID-19
severe disease
single-cell
Single-cell RNA sequencing
subset
syndrome
T cell
[DOI] 10.1038/s41591-020-0944-y [Article Type] Research
[DOI] 10.1038/s41591-020-0944-y [Article Type] Research