SARS-CoV-2 Antibody Isotypes in Systemic Lupus Erythematosus Patients Prior to Vaccination: Associations With Disease Activity, Antinuclear Antibodies, and Immunomodulatory Drugs During the First Year of the Pandemic예방 접종 전 전신 홍반성 루푸스 환자의 SARS-CoV-2 항체 아이소타입: 유행병 첫 해 동안 질병 활성, 항핵항체 및 면역조절 약물과의 연관성Immunology Published on 2021-08-272022-09-11 Journal: Frontiers in Immunology [Category] MERS, SARS, 진단, 치료기술, [키워드] a minor Activation activity acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 albumin all subjects analyzed anti-dsDNA antibodies antibody antibody isotypes Antibody Response antinuclear antibodies antinuclear antibody Arthritis Blood Blood Group BMI Cell cell receptor collected complement Complement activation complement-immunological terms coronavirus coronavirus disease Coronavirus disease 2019 correlated Course COVID-19 COVID-19-related symptom dose drug Effects ELISA envelope protein exposure to Fever followed by glucocorticoid Hydroxychloroquine IgA IgG IgM Impact include individual Infection interferon investigated isotype longitudinal samples Lupus lupus (SLE) lupus erythematosus minor multiplex neutralization (effect of) neutralizing capacity objective pandemic Patient patients with SARS-CoV-2 PCR-confirmed progression proportion Proteins respiratory Result Rheumatic diseases rheumatologist risk SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-COV-2 infection serological severe acute respiratory syndrome Coronavirus severe SARS severe SARS-CoV-2 SLE SLE patient smoking steroid Steroids subject Swedish Symptom systemic systemic lupus erythematosus the cell Thromboembolism type I interferon use of hydroxychloroquine vaccination were measured women Year [DOI] 10.3389/fimmu.2021.724047 PMC 바로가기 [Article Type] Immunology
Biochemical composition, transmission and diagnosis of SARS-CoV-2SARS-COV-2의 생화학 적 조성, 전염 및 진단Review Published on 2021-08-272022-09-01 Journal: Bioscience Reports [Category] MERS, SARS, 변종, 진단, [키워드] acute respiratory syndrome adoption antiretroviral drug biochemical caused Chain Reaction coronavirus coronavirus disease Coronavirus disease 2019 COVID- 19 COVID-19 COVID-19 pandemic COVID-19 testing CRISPR curtail death Diagnosis diagnosis of SARS-CoV-2 effective ELISA globe Health Organization healthcare human coronavirus immunological Infection lateral flow life-threatening Measures mode molecular mutant mutants pandemic polymerase chain polymerase chain reaction provide respiratory respiratory infection RT-PCR SARS-CoV-2 serological severe acute respiratory syndrome virus Spread the SARS-CoV-2 Transmission virus World Health Organization [DOI] 10.1042/BSR20211238 PMC 바로가기 [Article Type] Review
Persistence of Anti-S Titre among Healthcare Workers Vaccinated with BNT162b2 mRNA COVID-19Article Published on 2021-08-252022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] AIFA anti-S anti-S-RBD antibodies antibody approved authorization BNT BNT162b2 mRNA BNT162b2 mRNA vaccine consequence COVID-19 COVID-19 pandemic detectable domain drug Effective vaccines elderly ENCODE evaluate HCW HCWs Health healthcare worker Healthcare workers immunological protection Infection Italian Messenger RNA mRNA mRNA vaccine nucleoside-modified RNA operator operators Pfizer Phase I Protective antibody public health systems Safe SARS-CoV-2 SARS-CoV-2 antibody serological significantly lower spike glycoprotein the SARS-CoV-2 titre vaccination Vaccine worker [DOI] 10.3390/vaccines9090947 PMC 바로가기 [Article Type] Article
Simultaneous evaluation of antibodies that inhibit SARS-CoV-2 variants via multiplex assayResource and Technical Advance Published on 2021-08-232022-10-30 Journal: JCI Insight [Category] COVID-19, SARS, [키워드] ACE2 receptor ACE2-RBD Angiotensin-converting enzyme antibody Antibody therapeutics binding domain candidate complementary COVID-19 domains Effectiveness facilitate functional Immune escape immune escape mutations immunoglobulins inhibit SARS-CoV-2 inhibitory monoclonal antibody Multiplex assay N439K N501Y natural infection neutralizing antibody neutralizing capacity RBD RBD variant S477N SARS-CoV-2 receptor SARS-CoV-2 research serological Simultaneous Surveillance the SARS-CoV-2 vaccination Vaccine variant [DOI] 10.1172/jci.insight.150012 PMC 바로가기 [Article Type] Resource and Technical Advance
SARS-CoV-2 Seroprevalence Structure of the Russian Population during the COVID-19 PandemicSARS-COV-2 COVID-19 Pandemic 동안 러시아 인구의 Seroprevalence 구조Article Published on 2021-08-192022-09-01 Journal: Viruses [Category] MERS, SARS, 진단, 치료법, [키워드] accompanied addition age anti-SARS-CoV-2 antibody Asymptomatic asymptomatic form average Biotechnology Blood center change children Cohort conducted Contact contact with convalescent correlation COVID-19 COVID-19 pandemic cumulative decrease distribution District examined group groups healthy herd immunity immune Immunity increase in individual individuals Infection initial investigated longitudinal cohort study methodology Microbiology morbidity nucleocapsid nucleocapsid antigen Patient plasma Population Prevalence proportion ranged Region regions replaced REPLACED BY Russia SARS-CoV-2 SARS-CoV-2 pandemic separated serological seropositive seropositive individuals Seroprevalence Seven Structure the SARS-CoV-2 Thermo Scientific Volunteer volunteers was determined [DOI] 10.3390/v13081648 PMC 바로가기 [Article Type] Article
Serological Testing for COVID-19, Immunological Surveillance, and Exploration of Protective AntibodiesCOVID-19에 대한 혈청학적 검사, 면역학적 감시 및 보호 항체 탐색Immunology Published on 2021-08-192022-09-11 Journal: Frontiers in Immunology [Category] MERS, SARS, 진단, 치료기술, 치료법, 치료제, [키워드] 3CL animals antibody Antibody titer Antibody titers Antigen antigens Antiviral antiviral activity antiviral antibodies changes in circulation Combination Concentration correlation COVID-19 diagnosed Effectiveness ELISA assay Epidemiological study exploration greater human serum IgG IgG and IgM IgG antibody IgG level IgM antibodies IgM antibody immunoassay individual information Measures N protein neutralization activity nucleocapsid pathogenic PCR powerful tool protease reduction in SARS-CoV-2 SARS-CoV-2 protein SARS-CoV-2 proteins sensitivity serological Serological assay Serological testing seroneutralization shown target Testing Viral virus [DOI] 10.3389/fimmu.2021.635701 PMC 바로가기 [Article Type] Immunology
mRNA Vaccines Enhance Neutralizing Immunity against SARS-CoV-2 Variants in Convalescent and ChAdOx1-Primed SubjectsArticle Published on 2021-08-182022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] B.1.351 BNT162b2 booster cellular ChAdOx1-nCoV-19 characterized Combination convalescent convalescent plasma COVID-19-convalescent individual Donor facilitate heterologous vaccination regimes using mRNA vaccines may allow enhanced protection against SARS-CoV-2, including current VOCs identify IFN-γ response immune responses immunization immunological protection Immunological response individual individuals investigated moderate mRNA mRNA vaccine mRNA-1273 Neutralizing antibodies neutralizing antibody Neutralizing antibody response neutralizing capacity Observational cohort study receiving required RNA vaccines may facilitate rapid (re-) qualification of convalescent plasma donors with high titers of broadly neutralizing antibodies SARS-CoV-2 serological significantly subject triggered vaccinated individual vaccination Vaccine variants of concern VOCs widespread [DOI] 10.3390/vaccines9080918 PMC 바로가기 [Article Type] Article
COVID-19 clinical and laboratory diagnosis overviewReview Published on 2021-08-182022-10-30 Journal: Journal of the Egyptian Public Health Association [Category] COVID-19, [키워드] 2019-nCoV adopted approach clinical clinical decision clinical suspicion Community COVID-19 COVID-19 diagnosis COVID-19 infection Diagnosis diagnostics drastic false-negative Genetic global pandemic Isolation lab Laboratory measure novel corona virus outbreak PCR testing raise raised reported risk RT-PCR RT-PCR diagnosis RT-PCR kit SARS-CoV-2 sequence serologic test serological serology Spread therapeutic intervention Wuhan, China [DOI] 10.1186/s42506-021-00087-w PMC 바로가기 [Article Type] Review
Safety and humoral responses to BNT162b2 mRNA vaccination of SARS-CoV-2 previously infected and naive populationsSARS-COV-2의 BNT162B2 mRNA 백신 접종에 대한 안전성 및 유머 반응, 이전에 감염되고 순진한 집단Comparative Study Published on 2021-08-162022-09-01 Journal: Scientific Reports [Category] MERS, SARS, 진단, [키워드] BNT162b2 BNT162b2 mRNA COVID-19 vaccine BNT162b2 mRNA vaccination Cohort correlation COVID-19 COVID-19 vaccine demonstrated dose Efficacy Humoral response immune response individual individuals induce Infection Injections mRNA mRNA-based vaccine mRNA-based vaccines naïve of BNT162b2 Population populations regimen Reinfection required response risk Safe Safety SARS-CoV-2 serological Serological tests Seropositivity severe symptom single dose single vaccine Symptom the median vaccination vaccine dose vaccine injection Vaccines viral infection [DOI] 10.1038/s41598-021-96129-6 PMC 바로가기 [Article Type] Comparative Study
Serological prevalence of SARS-CoV-2 infection and associated factors in healthcare workers in a “non-COVID” hospital in Mexico CityResearch Article Published on 2021-08-122022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] antibody applied blood sample collected comparable conducted confirmed case Contagion counseling country COVID-19 pandemic cross-sectional death diagnostic test ELISA Factor fraction Frequency group groups healthcare worker help high mortality highest hospital identify individual individuals limit Mexico City National pandemic performed Prevalence Probability questionnaire Result SARS-CoV-2 SARS-COV-2 infection selected serological serological survey seropositive significantly higher Sociodemographic factor Spread study population working [DOI] 10.1371/journal.pone.0255916 PMC 바로가기 [Article Type] Research Article