Association of ventilator type with hospital mortality in critically ill patients with SARS-CoV2 infection: a prospective studyResearch Published on 2022-02-082022-10-28 Journal: Annals of Intensive Care [Category] COVID-19, [키워드] 95% CI acute respiratory distress Analysis ARDS association Characteristics COVID-19 Critically ill patient defined died evaluate Factor France hospital hospital discharge ICU identify immunodeficiency in-hospital mortality intensive care Intubated Invasive mechanical ventilation Kaplan–Meier survival curve less management median age men Mortality non-ICU outcome outcomes Patient patient group prospective observational study Prospective Study Result SARS-CoV2 SARS-CoV2 infection serum single-center Study design supplementary material syndrome Transport ventilated patient ventilator was performed was used [DOI] 10.1186/s13613-022-00981-2 PMC 바로가기 [Article Type] Research
Design, synthesis and in vitro evaluation of novel SARS-CoV-2 3CL pro covalent inhibitors새로운 SARS-CoV-2 3CL pro 공유 억제제의 설계, 합성 및 시험관 내 평가Article Published on 2022-02-052022-09-11 Journal: European journal of medicinal chemistry [Category] 신약개발, 치료제, [키워드] 3CL pro 3CLpro antiviral drug antiviral drugs coronavirus Coronavirus infection Coronavirus infections covalent inhibitors. COVID-19 pandemic cysteine demonstrated disease effort enzymatic activity in viral in vitro inhibitor inhibitors inhibitors of SARS-CoV-2 MERS MPro Outbreaks platform protease Replication reported SARS-CoV SARS-CoV-2 SARS-CoV2 starting point synthesis viral replication viruses was used were used [DOI] 10.1016/j.ejmech.2021.114046 PMC 바로가기 [Article Type] Article
Performance of the Abbott SARS-CoV-2 IgG serological assay in South African 2 patients남아프리카 2 명의 환자에서 Abbott SARS-COV-2 IgG 혈청 학적 분석의 성능Research Article Published on 2022-02-042022-09-10 Journal: PLoS ONE [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, 치료법, [키워드] Abbott Abbott SARS-CoV-2 IgG African Architect Asymptomatic clinical utility coronavirus coronavirus disease COVID-19 criteria detect diagnostic diagnostic testing ELISA evaluate highest IgG IgG antibodies IgG antibody in house ELISA in-house ELISA Infection infection rate lockdown negative control negative controls nucleocapsid participant Patient performance performed Pneumonia pneumonia case pneumonia cases positive patients Protein reported RT-qPCR SARS-CoV2 sensitivity Serological assay serology test South South Africa Support symptomatic syndrome the SARS-CoV-2 virus was tested were used with infection Wuhan Wuhan, China [DOI] 10.1371/journal.pone.0262442 PMC 바로가기 [Article Type] Research Article
Mycobacterium tuberculosis and SARS-CoV-2 Coinfections: A ReviewMicrobiology Published on 2022-02-032022-10-31 Journal: Frontiers in Microbiology [Category] COVID-19, [키워드] Activation acute respiratory syndrome affected alanine aminotransferase Algorithms article articles C-reactive protein cause Clinical management Coinfection consequence coronavirus coronavirus disease COVID-19 COVID-19 disease COVID-19 pandemic COVID-19 patients death Diagnosis diagnostic erythrocyte sedimentation rate evaluate Health health systems increase in indicated infectious agents information Interaction investigator lack lactate dehydrogenase Lymphocytes management Mortality mortality rate Mycobacterium tuberculosis pandemic Patient reduction respiratory symptom Result review risk risk factor SARS-CoV-2 SARS-CoV2 searched severity TB TB patients treated Treatment underlying disease Web of Science worsening [DOI] 10.3389/fmicb.2021.747827 PMC 바로가기 [Article Type] Microbiology
Remdesivir, Molnupiravir and Nirmatrelvir remain active against SARS-CoV-2 Omicron and other variants of concernArticle Published on 2022-02-012022-10-27 Journal: Antiviral Research [Category] Coronavirus, COVID-19, COVID19(2023년), Fulltext, SARS, [키워드] active against Alpha Antiviral antiviral activity antivirals Beta Cell Compound conserved Delta delta variant EIDD-1931 FIVE Gamma GFP GS-441524 high-content imaging in vitro Infection molnupiravir MPro Nirmatrelvir observation omicron other variant parent nucleoside Post-infection protease Protease inhibitor Remdesivir RNA polymerase SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants SARS-CoV2 serial dilution susceptible target gene target protein variants of concern Viral RNA virus VoC was determined [DOI] 10.1016/j.antiviral.2022.105252 PMC 바로가기 [Article Type] Article
Serum ferritin as a predictive biomarker in COVID-19. A systematic review, meta-analysis and meta-regression analysisCovid-19에서 예측 바이오 마커로서 혈청 페리틴.체계적인 검토, 메타 분석 및 메타 회귀 분석Meta-Analysis Published on 2022-02-012022-08-31 Journal: Journal of critical care [Category] MERS, 바이오마커, [키워드] Analysis Biomarker carried co-morbidities co-morbidity COVID-19 COVID-19 negative COVID-19 patient COVID-19 patients Critical critical COVID-19 patient critical COVID-19 patients database Diagnosis evaluate Factor ferritin ferritin level heterogeneity Hyperferritin ICU Inflammatory biomarker Interpretation male Male sex management mechanical ventilation Meta-analysis meta-regression Mild mild to moderate moderate Moderate COVID-19 morbidities non-survivor Non-survivors organ Patient Predictive Prognosis SARS-CoV2 searched Serum ferritin serum ferritin level severity survivor systematic review [DOI] 10.1016/j.jcrc.2021.09.023 PMC 바로가기 [Article Type] Meta-Analysis
COVID-19, gender and estroprogestins, what do we know?Review Published on 2022-02-012023-07-07 Journal: The European journal of contraception & reproductive health care : the [Category] COVID19(2023년), [키워드] combined hormonal contraceptives Cytokine storm Inflammation SARS-CoV2 vaccine-induced immune thrombotic thrombocytopenia [DOI] 10.1080/13625187.2021.2000959 [Article Type] Review
ADEM anti-MOG antibody-positive after SARS-CoV2 vaccinationSARS-CoV2 백신 접종 후 ADEM 항-MOG 항체 양성Article Published on 2022-02-012022-09-12 Journal: Neurological Sciences [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] SARS-CoV2 vaccination [DOI] 10.1007/s10072-021-05761-7 PMC 바로가기 [Article Type] Article
Predictive scores for the diagnosis of Pulmonary Embolism in COVID-19: A systematic reviewArticle Published on 2022-02-012023-07-07 Journal: International Journal of Infectious Diseases [Category] COVID19(2023년), [키워드] COVID-19 Prediction Rule Pulmonary embolism SARS-CoV2 score Thromboembolism [DOI] 10.1016/j.ijid.2021.11.038 PMC 바로가기
Impacts of rapid mass vaccination against SARS-CoV2 in an early variant of concern hotspot우려 핫스팟의 초기 변종에서 SARS-CoV2에 대한 신속한 대량 백신 접종의 영향Observational Study Published on 2022-02-012022-09-10 Journal: Nature Communications [Category] COVID19(2023년), MERS, SARS, 변종, 임상, [키워드] Beta Beta variant BNT162b2 Border caused conducted control group District dose effective Epidemiology Europe excluded hospital hospitalisations hotspot ICU admissions Impact infections inoculated mass mass vaccination of BNT162b2 outbreak outcome Outcomes research Pfizer/BioNTech Population reduced infection reduced infections SARS-CoV-2 SARS-CoV2 significant decrease Spread Statistical methods the District vaccinate vaccination Vaccines variant variants variants of concern [DOI] 10.1038/s41467-022-28233-8 PMC 바로가기 [Article Type] Observational Study