Brainstem neuropathology in two cases of COVID-19: SARS-CoV-2 trafficking between brain and lungCOVID-19의 두 가지 사례에서 뇌간 신경병리학: 뇌와 폐 사이의 SARS-CoV-2 트래피킹Case Reports Published on 2021-05-182022-09-10 Journal: Journal of Neurology [Category] SARS, 치료기술, [키워드] abnormality Activation Anatomy Antigen Autopsies Brain Brainstem brainstem reflex cells controls COVID-19 COVID-19 negative COVID-19 patients cranial cranial nerves demonstrated died element Evidence exhibited expression feature glial cells histopathological examination immunohistochemistry include increase in lung material Medulla oblongata negative patients nervous system Neurological COVID-19 Neuron neuronal Neuropathology oblongata Other pathophysiology Patient reported respiratory centers Respiratory failure Result SARS-Co SARS-CoV-2 SARS-CoV-2 nucleoprotein Spread supplementary material the SARS-CoV-2 two COVID-19 patients two patients vagus nerve Viral widespread [DOI] 10.1007/s00415-021-10604-8 PMC 바로가기 [Article Type] Case Reports
A metabolomic endotype of bioenergetic dysfunction predicts mortality in critically ill patients with acute respiratory failureArticle Published on 2021-05-182022-10-04 Journal: Scientific Reports [Category] 바이오마커, [키워드] abnormality accumulating Acute respiratory failure Admission alteration Analysis ANOVA applied ARF association bile acids Bioavailability Biochemistry Biomarkers biosynthetic change characterized cofactor Critically ill patient detect determine disorders dysfunction Efficiency Evidence FDR high accuracy hospital discharge include intensive care mechanical ventilation Medical research metabolism metabolite metabolome metabolomic mitochondrial morbidity and mortality Mortality NADP nicotinamide adenine dinucleotide non-survivor outcome pathway Patient phosphate predict predicted Prevalence Quantitative reduce mortality Respiratory failure Riboflavin semi-quantitative Sepsis serum severity Significant substrate survival survivor Survivors Systems biology target Treatment [DOI] 10.1038/s41598-021-89716-0 PMC 바로가기 [Article Type] Article
COVID-19: A Potential Cause of Non-convulsive Status EpilepticusNeurology Published on 2021-05-152022-10-31 Journal: Cureus [Category] COVID-19, [키워드] abnormality acute respiratory syndrome Brain Case report cause Central nervous system cerebrospinal fluid Complete Confusion coronavirus Coronavirus disease 2019 COVID-19 COVID-19 infection D-dimer described Drug screening epileptiform hyponatremia lactate dehydrogenase magnetic resonance imaging male manifested Mild Nasopharyngeal swab neurological manifestations Patient polymerase chain positive Potential Protein repeated reported respiratory symptoms responsible reverse transcription SARS-CoV-2 SARS-COV-2 infection scale Seizure shown status status epilepticus the patient tomography Treatment vital sign [DOI] 10.7759/cureus.15041 PMC 바로가기 [Article Type] Neurology
Saffron: A potential drug-supplement for severe acute respiratory syndrome coronavirus (COVID) managementReview article Published on 2021-05-142022-10-05 Journal: Heliyon [Category] 치료제, [키워드] abnormality acute respiratory syndrome alleviate anti-depressant Anti-inflammatory antioxidant Anxiety boost immunity bronchitis Care caused Compound coronavirus COVID COVID-19 COVID-19 infection COVID-19 symptom Crocus sativus L. Depression effective ENhance epidemiological studies evade Fever functions Health help herbal medicines Human immune immune response Immunity include Isolation Laboratory lockdown magnitude management Medicines Mutation Pandemics patients Post-infection Post-traumatic stress disorder problems quarantine renal respiratory disorders Safe Saffron SARS-CoV-2 Stress survivor Transmission treat Vaccine virus with COVID-19 [DOI] 10.1016/j.heliyon.2021.e07068 [Article Type] Review article
Cardiovascular Impacts on COVID-19 Infected PatientsCardiovascular Medicine Published on 2021-05-132022-10-31 Journal: Frontiers in Cardiovascular Medicine [Category] COVID-19, [키워드] Abnormalities abnormality ACE2 Administered affected angiotensin-converting enzyme 2 Arrhythmias binding site cardiovascular Cardiovascular Abnormalities cardiovascular condition cardiovascular diseases cardiovascular risk factors cardiovascular system category Cell cell injury clinically Coagulation COVID-19 COVID-19 virus Direct drug Endothelial cell heart failure Impact include Infection Inflammation lung mechanism Myocardial myocardial injury myocarditis organ over Primary infection Protein regulate replication mechanism reported Respiratory system risk factor SARS-CoV-2 SARS-CoV-2 virus Severe Acute Respiratory Syndrome Corona Virus 2 surface receptor Symptomatic treatment target the patient therapy tissue damage viral infection viral replication viral spike with COVID-19 [DOI] 10.3389/fcvm.2021.670659 PMC 바로가기 [Article Type] Cardiovascular Medicine
Can Asymptomatic or Non-Severe SARS-CoV-2 Infection Cause Medium-Term Pulmonary Sequelae in Children?Pediatrics Published on 2021-05-132022-10-31 Journal: Frontiers in Pediatrics [Category] COVID-19, [키워드] abnormality acute respiratory syndrome Adults airway airway resistance all subject alteration antibodies Asymptomatic Can cause children Cohort Complication complications coronavirus correlation COVID-19 detect develop diffusing eligible enrolled enzyme evaluate evaluated female Follow-up immune immune response IRCCS Italy less Long COVID lung male median age observation Older Patient performed pulmonary pulmonary complication Pulmonary function reported SARS-CoV-2 SARS-COV-2 infection spirometry subject Symptomatic patients symptomatic SARS-CoV-2 infection Ultrasound were used [DOI] 10.3389/fped.2021.621019 PMC 바로가기 [Article Type] Pediatrics
Elevated transaminases and hypoalbuminemia in Covid-19 are prognostic factors for disease severity코비드-19의 아미노전이효소 증가 및 저알부민혈증은 질병 중증도의 예후 인자입니다Article Published on 2021-05-132022-09-10 Journal: Scientific Reports [Category] SARS, 바이오마커, 치료법, [키워드] 95% CI Abnormalities abnormality Admission Alanine alanine aminotransferase alkaline phosphatase ALT Aminotransferase analyzed aspartate Aspartate aminotransferase AST baseline cause cohort study Community Course determine Diagnosis disease course disease severity elevated Elevation elevations Evidence evidence of gastroenterology Gastrointestinal symptom gastrointestinal symptoms Hemodialysis hospital Hospital admission Hypoalbuminemia Hypotension ICU ICU admission increased mortality intubation laboratory data liver liver enzymes Liver injury marker Medical research Patient phosphatase predict Prognostic factor Prognostic factors Prognostic markers retrospective severity significantly the disease transaminase Vasopressor vasopressors [DOI] 10.1038/s41598-021-89340-y PMC 바로가기 [Article Type] Article
Cardiac Involvement in Recovered Patients From COVID-19: A Preliminary 6-Month Follow-Up StudyCardiovascular Medicine Published on 2021-05-132022-10-31 Journal: Frontiers in Cardiovascular Medicine [Category] COVID-19, [키워드] abnormality accompanied Admission Analysis analyzed Aspartate aminotransferase Biomarker cardiac cardiac injury Cardiac magnetic resonance imaging Cardiopulmonary circulating clinical coronavirus disease COVID-19 COVID-19 patient creatinine develop discharge discharged enrolled events Evidence Exercise capacity exhibited fibrosis Follow-up follow-up study form High-sensitivity C-reactive protein Hospitalization in both groups Inflammatory Inflammatory factor information Injury interquartile range Involvement Laboratory lactate dehydrogenase magnetic resonance imaging manifestation medications myocardial injury N-terminal nonspecific Patient peptide positive Premature proportion Quality of life recovered recovered patient recovered patients reported Self-reported symptoms sequence significantly higher ST-T changes ST2 statistical difference statistically significant difference sustained Symptom the patient troponin I university was collected Wuhan [DOI] 10.3389/fcvm.2021.654405 PMC 바로가기 [Article Type] Cardiovascular Medicine
Giant intracardiac thrombosis in an infant with leukaemia and prolonged COVID-19 viral RNA shedding: a case reportCase Report Published on 2021-05-122022-10-29 Journal: Thrombosis Journal [Category] COVID-19, [키워드] abnormality Acute lymphoblastic leukemia Administered Case report Cell Chemotherapy children clinically Coagulation complicate Complication Computed tomography continuous monitoring Course COVID-19 described diagnostic disease echocardiographic eight Endothelial dysfunction enoxaparin Fever High-resolution HRCT indicated induce Inflammation intracardiac leukemia manifestation myocardial involvement nasopharyngeal patients patients with COVID-19 PCR Pediatric patient platelet activation positive prolonged viral shedding reduction in reported RNA SARS-CoV‐2 therapeutic thrombosis thrombotic vena venous Viral RNA [DOI] 10.1186/s12959-021-00285-8 PMC 바로가기 [Article Type] Case Report
The prognostic significance of electrocardiography findings in patients with coronavirus disease 2019: A retrospective study2019년 코로나바이러스 질환 환자에서 심전도 소견의 예후적 의미: 후향적 연구Observational Study Published on 2021-05-112022-09-12 Journal: Clinical Cardiology [Category] SARS, 임상, 진단, [키워드] 95% CI abnormality adjusted Admission age arrhythmia Arrhythmias assigned association Atrioventricular block cardiac injury Characteristics Clinical data Comorbidities coronavirus coronavirus disease Coronavirus disease 2019 COVID‐19 COVID‐19 patients death demographic deviation disease ECG ECG abnormalities electrocardiographic Electrocardiography higher risk Hospitalization identify Injury male median Mortality mortality risk multivariable Cox regression outcome pandemic Patient patients died prognostic Q wave QTc interval reached Result Retrospective study risk scoring system significantly higher tissue [DOI] 10.1002/clc.23628 PMC 바로가기 [Article Type] Observational Study