PACIFIC: a lightweight deep-learning classifier of SARS-CoV-2 and co-infecting RNA virusesPACIFIC: SARS-CoV-2 및 공동 감염 RNA 바이러스의 경량 딥 러닝 분류기Article Published on 2021-02-052022-09-10 Journal: Scientific Reports [Category] MERS, 치료기술, [키워드] Algorithm Cell culture Classifier clinical microbiology co-infecting Co-infection Computational biology and bioinformatics Concentration COVID-19 patients datasets detect Disease progression genetics global pandemic identify in silico in vitro independent Infection Infectious-disease diagnostics Microbiology Molecular biology occur Pathogens Patient Precision precision and recall recall respiratory respiratory virus RNA RNA virus RNA-seq data SARS-CoV-2 severity Viral viral infection viral infections Virology virus viruses [DOI] 10.1038/s41598-021-82043-4 PMC 바로가기 [Article Type] Article
Thapsigargin Is a Broad-Spectrum Inhibitor of Major Human Respiratory Viruses: Coronavirus, Respiratory Syncytial Virus and Influenza A VirusArticle Published on 2021-02-032022-10-28 Journal: Viruses [Category] COVID-19, 신종인플루엔자, [키워드] acute infections addition Antiviral antiviral response ATPase block broad-spectrum common cold coronavirus coronavirus coronavirus OC43 COVID-19 vaccine derivatives disease effective Effective vaccines H1N1 Host Human immortalized include induce Infection influenza A virus Influenza virus inhibit inhibitor inhibitory innate immune Innate immunity Major mice mouse OC43 oseltamivir primary human cells Remdesivir Replication respiratory respiratory syncytial virus respiratory virus ribavirin RSV SARS-CoV-2 significantly thapsigargin treat vaccination virus [DOI] 10.3390/v13020234 PMC 바로가기 [Article Type] Article
Impact of climatic, demographic and disease control factors on the transmission dynamics of COVID-19 in large cities worldwideResearch Paper Published on 2021-02-032022-10-28 Journal: One Health [Category] COVID-19, [키워드] association basic reproduction number caused China Climate country COVID-19 COVID-19 pandemic COVID-19 transmission cumulative demographic disease early phase effort epidemic response Evidence Factor Factors greater Growth Curve Health Impact infections Local Logistic Metropolitan areas OLS ordinary least square Other pandemic R0 Radiation Rate regions Research respiratory virus robust SARS-CoV-2 Seasonal influenza sensitivity Socio-economic South Africa South America temperature the epidemic the SARS-CoV-2 virus Transmission Transmission dynamics variable Variation [DOI] 10.1016/j.onehlt.2021.100221 PMC 바로가기 [Article Type] Research Paper
Graphene Sheets with Defined Dual Functionalities for the Strong SARS‐CoV‐2 InteractionsCommunication Published on 2021-02-022022-10-29 Journal: Small (Weinheim an der Bergstrasse, Germany) [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome aliphatic chain antiviral activity atomic caused Cell Concentration coronavirus Coronavirus infections Coronavirus replication derivative disrupt disrupting electrostatic electrostatic interaction Graphene graphene‐based polyglycerol sulfates Health highlight human cell hydrophobic hydrophobic interaction inefficient Infection inhibit inhibitor investigated Microscopy mutate pandemic platform present PROTECT respiratory virus responsible rupture SARS‐CoV‐2 SARS‐CoV‐2 inhibitor Sheet spike glycoprotein Strong therapeutic therapeutic agent Toxicity Treatment Vaccine viral envelope virion virucidality virus viruses while [DOI] 10.1002/smll.202007091 PMC 바로가기 [Article Type] Communication
siRNA Therapeutics against Respiratory Viral Infections—What Have We Learned for Potential COVID‐19 Therapies?Review Published on 2021-01-272022-10-28 Journal: Advanced Healthcare Materials [Category] COVID-19, [키워드] addition Antiviral antiviral drug antiviral drugs cause conserved COVID‐19 death develop effective emerging respiratory virus evaluated FIVE Health highlighting host gene host–viral interactions Infection inhalation inhibiting Modification nanomedicine offer outbreak pandemic Potential Prevalence Prevent prophylactically provide pulmonary pulmonary delivery Region regions Replication respiratory respiratory virus respiratory viruses resulting RNAi pathway SARS‐CoV‐1 SARS‐CoV‐2 SARS‐CoV‐2 sequence siRNA target cell target gene therapeutic use Therapeutics Treatment Vaccine viral genome viral infection viral replication viral respiratory [DOI] 10.1002/adhm.202001650 PMC 바로가기 [Article Type] Review
Viral co-infections among SARS-CoV-2-infected children and infected adult household contactsSARS-CoV-2에 감염된 어린이와 감염된 성인 가구 접촉자 간의 바이러스 동시 감염Short Communication Published on 2021-01-272022-09-11 Journal: European journal of pediatrics [Category] MERS, SARS, 치료기술, [키워드] Adults children circulation Co-infection collected COVID-19 evaluated exposure to Familial clusters had more household contact household contacts infected with SARS-CoV-2 less Other respiratory viruses outbreak partial lockdown reduced respiratory respiratory virus respiratory viruses SARS-CoV-2 School Schools significantly more the SARS-CoV-2 Viral viral respiratory virus viruses [DOI] 10.1007/s00431-021-03947-x PMC 바로가기 [Article Type] Short Communication
Factors associated with admission to intensive care units in COVID-19 patients in Lyon-FranceObservational Study Published on 2021-01-272022-10-04 Journal: PLoS ONE [Category] MERS, 임상, [키워드] Admission age analysed applied Celsius Characteristics Chi-square collected Community COVID-19 COVID-19 patient CRP determinant died discharged elevated Factor Fisher exact test fixed Forward hospital Hospital admission Hospital stay hospitalisation Hospitalization Hospitalized hospitalized COVID-19 patients hospitalized patient ICU ICUs identify IMPROVE intensive care unit Intervention less Logistic regression lung Mann-Whitney monocytopenia multivariable logistic regression Multivariable regression onset of symptom outcome oxygen saturation Patient patients patients hospitalized presenting Prognosis respiratory virus Result risk SARS-CoV-2 Sex socio-demographic Spread temperature variable [DOI] 10.1371/journal.pone.0243709 PMC 바로가기 [Article Type] Observational Study
siRNA Therapeutics against Respiratory Viral Infections—What Have We Learned for Potential COVID‐19 Therapies?호흡기 바이러스 감염에 대한 siRNA 치료제 - 잠재적인 COVID-19 치료제에 대해 우리는 무엇을 배웠습니까?Review Published on 2021-01-272022-09-10 Journal: Advanced Healthcare Materials [Category] 치료제, [키워드] addition Antiviral antiviral drug antiviral drugs cause choice conserved COVID‐19 death develop Economy effective emerging respiratory virus evaluated FIVE global health Health highlighting host gene host genes host–viral interactions Infection infection sites Influenza inhalation inhibiting life Modification nanomedicine offer outbreak pandemic Potential Prevalence Prevent progress report prophylactically provide pulmonary pulmonary delivery Region regions Replication respiratory respiratory virus respiratory viruses resulting RNAi pathway SARS‐CoV‐1 SARS‐CoV‐2 SARS‐CoV‐2 sequence siRNA siRNAs swine flu target cell target cells target gene therapeutic use Therapeutics Treatment Vaccine Viral viral genome viral infection viral replication viral respiratory viruses [DOI] 10.1002/adhm.202001650 PMC 바로가기 [Article Type] Review
Risk factors and protective measures for healthcare worker infection during highly infectious viral respiratory epidemics: A systematic review and meta-analysisReview Published on 2021-01-252022-10-30 Journal: Infection Control and Hospital Epidemiology [Category] COVID-19, COVID19(2023년), MERS, SARS, 신종인플루엔자, [키워드] 95% CI Analysis certainty of evidence CINAHL Cochrane Central controls COVID-19 pandemic database Endotracheal intubation estimate Face mask Factor GRADE framework greater H1N1 H5N1 HCW HCWs healthcare worker IMPROVE in viral Infection Infection prevention infection risk Influenza influenza A involved management measure MERS Meta-analysis meta-regression Middle East Pandemics pathogen-specific PROTECT Protective reduced Respirator Respiratory Coronavirus respiratory virus risk risk factor SARS-CoV-2 searched stratified surgical syndrome systematic review viral respiratory virus [DOI] 10.1017/ice.2021.18 PMC 바로가기 [Article Type] Review
Evaluation of Seasonal Respiratory Virus Activity Before and After the Statewide COVID-19 Shelter-in-Place Order in Northern CaliforniaResearch Published on 2021-01-252022-10-29 Journal: JAMA Network Open [Category] COVID-19, MERS, [키워드] 95% CI activities activity acute respiratory syndrome age Analysis association cohort study Community conducted coronavirus coronavirus disease Coronaviruses COVID-19 Davis decrease Demonstrating engage enterovirus infection exposure finding Frame Health implication Importance in viral incidence rate include infections Influenza Laboratory Lower maintain measure much lower objective occurred organism other respiratory virus pandemic participant pathogen Pathogens physical distancing Point positive result positive test result Prevent Public public health Regression analyses Relevance respiratory respiratory syncytial virus respiratory viral respiratory virus Result rhinovirus SARS-CoV-2 transmission School seasonal setting statistically significant transmission rate viral respiratory virus wear face masks [DOI] 10.1001/jamanetworkopen.2020.35281 PMC 바로가기 [Article Type] Research