Comparison of Moderna versus Pfizer-BioNTech COVID-19 vaccine outcomes: A target trial emulation study in the U.S. Veterans Affairs healthcare systemResearch article Published on 2022-03-052022-10-05 Journal: EClinicalMedicine [Category] 임상, [키워드] 95% CI adjusted hazard ratio Affair age all age groups analyzed BNT162b2 category clinical trials Comorbidity COVID-19 vaccination COVID-19 vaccine death delta variant Department Electronic health records finding follow-up period follow-up time funding greater Healthcare system Hospitalization Infection less Medicare Moderna mRNA COVID-19 vaccine mRNA-1273 National occurred outcome Pfizer-BioNTech predominant propensity score matching rates of infection recipient recipients risk risk of infection SARS-COV-2 infection SARS-CoV-2 infections shown significantly lower statistically significant the vaccine Trial vaccination Vaccine vaccine dose vaccine group veteran [DOI] 10.1016/j.eclinm.2022.101326 [Article Type] Research article
The impact of COVID-19 continuous containment and mitigation strategy on the epidemic of vector-borne diseases in ChinaResearch Published on 2022-03-052022-10-28 Journal: Parasites & Vectors [Category] COVID-19, MERS, SARS, [키워드] average China Contamination coronavirus disease COVID-19 COVID-19 mitigation decrease Disease activity FIVE incidence Mitigation and contamination strategy Mobility morbidity Mortality mortality rate National Health Commission predicted prediction reduction Result significantly significantly lower supplementary material the epidemic Vector-borne disease vector-borne diseases [DOI] 10.1186/s13071-022-05187-w PMC 바로가기 [Article Type] Research
SARS-2 COVID-19-induced immunity response, a new prognostic marker for the pregnant population correlates inversely with neonatal Apgar scoreOriginal Paper Published on 2022-03-052022-10-29 Journal: Infection [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] accompanied Admission APGAR score appear association Biomarkers clinician collected Complication complications correlated COVID-19 COVID-19 infection COVID-19 patient defined distress exhibited facilitate haematological parameter Haematology help Hypothesis hypothesised immune response Immunity impacted Intensive Intervention Laboratory monocyte mother Neonatal Neonate neutrophil non-pregnant females outcome outcomes Patient perinatal health populations predict Pregnancy pregnant pregnant female pregnant females pregnant patient pregnant patients pregnant population prevalent Prognosis Prognostic marker PROTECT reduce response Result significantly significantly lower subject tested WBC [DOI] 10.1007/s15010-022-01773-3 PMC 바로가기 [Article Type] Original Paper
Human serum from SARS-CoV-2-vaccinated and COVID-19 patients shows reduced binding to the RBD of SARS-CoV-2 Omicron variantSARS-COV-2- 진화 및 COVID-19 환자의 인간 혈청은 SARS-COV-2 OMICRON 변이체의 RBD에 대한 결합 감소를 보여줍니다.Research Article Published on 2022-03-032022-09-10 Journal: BMC Medicine [Category] MERS, SARS, 변종, [키워드] ACE2 ACE2 binding addition analyzed angiotensin angiotensin-converting enzyme-2 Anti-RBD antibodies Anti-RBD antibody Antibody titer Antibody titers Beta Beta variant (B.1.351) Betacoronavirus binding BNT162b2 boost booster caused COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 patients D614G Delta Delta variant (B.1.617.2) Efficacy ELISA Evidence Evolution Human human Angiotensin-converting enzyme Human angiotensin-converting enzyme-2 receptor (ACE2) human sera Immune escape insect cells less Mutation neutralization Neutralizing antibodies omicron Omicron variant Omicron variant (B.1.1.529) produced protocol RBD RBD binding RBD variants RBDs receptor Receptor-binding domain Receptor-binding domain (RBD) recipient reduced reduction in restored Result SARS-CoV-2 sera serum significantly lower Spike protein supplementary material the RBD the receptor-binding domain the spike protein vaccinated individuals vaccination vaccinee vaccinees variant Virus neutralization VoC VOCs wild type Wuhan Wuhan strain [DOI] 10.1186/s12916-022-02312-5 PMC 바로가기 [Article Type] Research Article
Comparison of Outcomes and Process of Care for Patients Treated at Hospitals Dedicated for COVID-19 Care vs Other HospitalsResearch Published on 2022-03-032022-10-29 Journal: JAMA Network Open [Category] COVID-19, MERS, SARS, [키워드] 95% CI analyses association Care Cohort cohort study collected Complication Confirmed COVID-19 infection Corticosteroid COVID-19 demographic characteristics evaluate evaluated exposure finding High-dose hospital hospitals Importance In-hospital in-hospital mortality Infection Logistic regression lower mortality measure median age men Mortality mortality rate multivariate objective Odds ratio Other outcome pandemic Pandemics participant Patient patients treated patients with COVID-19 performed Point Primary outcome Process propensity score matching reducing Relevance Remdesivir Result retrospective cohort study Secondary outcomes setting significantly higher significantly lower study period Support System the SARS-CoV-2 Thrombosis prophylaxis Tocilizumab treated Treatment women [DOI] 10.1001/jamanetworkopen.2022.0873 PMC 바로가기 [Article Type] Research
Perceptions of green space usage, abundance, and quality of green space were associated with better mental health during the COVID-19 pandemic among residents of DenverResearch Article Published on 2022-03-022022-10-28 Journal: PLoS ONE [Category] COVID-19, [키워드] adjusted Anxiety association average benefit buffer confounding variables COVID-19 COVID-19 pandemic cross-sectional survey Depression depression score distress Evidence FIVE Generalized linear model impacted mental health normalized observé pandemic Perceived Perceived stress Perception physical provide question Result significantly significantly higher significantly lower Sociodemographic Stress Stressor stressors variable variables vegetation was measured [DOI] 10.1371/journal.pone.0263779 PMC 바로가기 [Article Type] Research Article
Mental health, learning behaviour and perceived fatigue among university students during the COVID-19 outbreak: a cross-sectional multicentric study in the UAEResearch Published on 2022-03-022022-10-28 Journal: BMC Psychology [Category] COVID-19, MERS, SARS, [키워드] ANOVA approach Characteristics children conducted consequence correlated COVID COVID-19 COVID-19 outbreak cross-sectional determine Educational institution Effect emotional evaluate events fatigue Fatigue level female Health help Home confinement-related stress IMPROVE indicate introduced inventory learning maintain majority mental health moderate outbreak pandemic participated performed physical positively correlated preventive measure Psychological distress Psychological well-being quarantine reduce reduced reducing Result reveal scale second significantly lower Stress t-test United Arab Emirate Well-being were used [DOI] 10.1186/s40359-022-00758-z PMC 바로가기 [Article Type] Research
Safety and humoral response rate of inactivated and mRNA vaccines against SARS-CoV-2 in patients with Multiple Sclerosis다발성 경화증 환자에서 SARS-CoV-2에 대한 비활성화 및 mRNA 백신의 안전성 및 체액 반응률Observational Study Published on 2022-03-012022-09-12 Journal: Multiple sclerosis and related disorders [Category] COVID19(2023년), MERS, SARS, 임상, 진단, [키워드] adenoviral vector vaccine Adverse age Analysis anti-SARS-CoV-2 vaccines Antibody titre antibody titres booster collected Complete COVID-19 Effectiveness Europe event Evidence first vaccination help humoral Humoral response inactivated Inactivated vaccine Inactivated virus information local pain mRNA mRNA vaccine Multiple multiple sclerosis no increase North America outcome Oxford-AstraZeneca Patient patient cohort patients performed populations positive predictor Protein receiving Safe Safety SARS-CoV-2 sclerosis selected significantly lower therapy vaccination Vaccine virus was determined were recorded women [DOI] 10.1016/j.msard.2022.103690 PMC 바로가기 [Article Type] Observational Study
Association of Early Aspirin Use With In-Hospital Mortality in Patients With Moderate COVID-19Randomized Controlled Trial Published on 2022-03-012022-10-05 Journal: JAMA Network Open [Category] 임상, [키워드] 95% CI adults hospitalized African American age Asian Aspirin benefit Blood calculated cerebral hemorrhage Characteristics Cohort cohort study Complication conditions COVID COVID-19 Efficacy enrolled evaluate gastrointestinal hemorrhage groups health system Hemorrhagic Hospitalization Hospitalized hospitalized patient in-hospital mortality include inverse IQR logistic regression models Moderate COVID-19 Mortality observational study occur occurred Odds ratio outcome Patient patients patients older patients with comorbidity patients with moderate Primary outcome Probability randomized clinical trial receiving reduce reduced screened secondary outcome significantly lower study inclusion the United State thrombosis Treatment was used Weighting white with COVID-19 [DOI] 10.1001/jamanetworkopen.2022.3890 PMC 바로가기 [Article Type] Randomized Controlled Trial
Expressions and significances of CTSL, the target of COVID-19 on GBMCTSL의 표현 및 중요성, GBM에서 Covid-19의 목표Article Published on 2022-03-012022-08-31 Journal: Journal of cancer research and clinical oncology [Category] MERS, SARS, 바이오마커, [키워드] analyzed Apoptosis association B cell biological activity Brain tissues cathepsin cathepsin L CD8 Cell Coronavirus infection correlated COVID-19 CTSL database expression level Glioblastoma glioblastoma multiforme growth Immune cell infiltration immune infiltration independent Infection inhibitor investigated mitochondrial New coronavirus overall survival Patient patients Prognosis Prognostic factor Proteases purity reduced risk significantly significantly lower subsequent survival survival rate T cell the cell therapeutic target tissue virus was tested [DOI] 10.1007/s00432-021-03843-9 PMC 바로가기 [Article Type] Article