Urinary Levels of SARS-CoV-2 Nucleocapsid Protein Associate With Risk of AKI and COVID-19 Severity: A Single-Center Observational StudyMedicine Published on 2021-05-252022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] 95% CI ACE2 Acute kidney injury acute respiratory syndrome addition AKI albumin Associate association cellular membrane Combination contribute Coronavirus-2 COVID-19 COVID-19 patients COVID-19 severity death disease evaluate examined ICU ICU admission Injury intensive care investigated kidney Kidney injury Level marker outcome Patient plasma Premature prospective observational study Protein renal risk risk factor risk prediction SARS-CoV-2 SARS-CoV-2 disease 2019 SARS-COV-2 infection SARS-CoV-2 N severe acute respiratory syndrome coronavirus-2 severity single-center supportive care TMPRSS2 urinary viral infection with COVID-19 [DOI] 10.3389/fmed.2021.644715 PMC 바로가기 [Article Type] Medicine
High Expression of ACE2 and TMPRSS2 at the Resection Margin Makes Lung Cancer Survivors Susceptible to SARS-CoV-2 With Unfavorable PrognosisOncology Published on 2021-05-212022-10-31 Journal: Frontiers in Oncology [Category] COVID-19, [키워드] ACE2 acute respiratory syndrome Analysis cancer patient Clinical characteristics clinical symptom conducted coronavirus Coronavirus disease 2019 Course COVID-19 diagnosed diagnosed with COVID-19 elevated expression Factor General population Hospitalization Huoshenshan Hospital individual individuals lung cancer margin median time molecular non-cancerous outcome Patient patients with COVID-19 Resection responsible Result retrospective cohort study SARS-CoV-2 Single Cell single-center Spread survivor Survivors susceptibility Symptom symptom onset the disease tissue TMPRSS2 TMPRSS2 level Treatment Wuhan [DOI] 10.3389/fonc.2021.644575 PMC 바로가기 [Article Type] Oncology
Intravenous immunoglobulin-based adjuvant therapy for severe COVID-19: a single-center retrospective cohort study중증 COVID-19에 대한 정맥 면역글로불린 기반 보조 요법: 단일 센터 후향적 코호트 연구Research Published on 2021-05-212022-09-01 Journal: Virology Journal [Category] SARS, 진단, [키워드] adjuvant therapy center China clinical evidence confounding factors coronavirus disease Coronavirus disease 2019 COVID-19 death demographic data end point glucocorticoid Glucocorticoids hospital Hospital length of stay Hospital mortality Hospital stay Immunoglobulin IMPROVE in-hospital mortality in-hospital mortality rate Intravenous immunoglobulin IVIG Laboratory laboratory-confirmed lack mechanical ventilation Mortality Mountain National Health Commission objective Patient patient information Primary outcome Primary outcomes reached Regional respiratory Result retrospective cohort study SARS-CoV-2 secondary outcome severe COVID-19 severe COVID-19 patients severely ill patient single-center statistically significant Support therapy Treatment two group two groups unit was collected [DOI] 10.1186/s12985-021-01575-3 PMC 바로가기 [Article Type] Research
Safety of systemic anti-cancer treatment in oncology patients with non-severe COVID-19: a cohort studyObservational Study Published on 2021-05-202022-10-04 Journal: BMC Cancer [Category] SARS, 임상, [키워드] acute respiratory syndrome Admission Adult patient Adverse adverse event adverse events ambulatory anti-cancer treatment association Belgium bleeding event cancer patient cancer treatment cohort study Common Terminology Criteria Coronavirus-2 COVID-19 COVID-19 pandemic determine disease eligible patient hematological incidence Infection initial intensive care management MOST neutropenia Non-severe COVID-19 occurred Odds ratio oncology oncology patient outcome oxygen supplementation pandemic pandemic coronavirus Patient patients performance status positive remained reported required Result Risk factors RT-PCR Safe Safety SARS-CoV-2 SARS-CoV-2 RT-PCR test SARS-CoV-2-positive patient SARS-CoV-2-positive patients Serological testing serology severe COVID-19 single-center solid tumor supplementary material systemic systemic anti-cancer therapy Systemic anti-cancer treatment therapy treated Treatment [DOI] 10.1186/s12885-021-08349-8 PMC 바로가기 [Article Type] Observational Study
Emergency Tracheal Intubation in Patients with COVID-19: A Single-center, Retrospective Cohort StudyCritical Care Published on 2021-05-172022-10-28 Journal: Western Journal of Emergency Medicine [Category] COVID-19, SARS, [키워드] adverse events airway airway management average cohort of patient collected data Complication Control COVID-19 COVID-19 case Desaturation Descriptive analysis eligible Emergency for inclusion Health increase in independent intubation no difference Novel coronavirus number of attempts nurse anesthetist oxygen pandemic Patient performed positive positive COVID-19 recorded resident Result significantly more single-center tracheal variable Video laryngoscopy was used [DOI] 10.5811/westjem.2020.2.49665 PMC 바로가기 [Article Type] Critical Care
Accuracy of a Novel SARS-CoV-2 Antigen-Detecting Rapid Diagnostic Test from Standardized Self-Collected Anterior Nasal SwabsArticle Published on 2021-05-132022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] 95% confidence interval acute respiratory syndrome Ag-RDT Anterior Asymptomatic Concentration coronavirus COVID-19 COVID-19 diagnostic testing criteria Endpoint enrolled equipment evaluated exclusion healthcare personnel increasingly individuals infected individual less medium meet nasal nasal swabs nasopharyngeal sample novel offer pandemic participant Participants Patient PCR performed point of care polymerase chain positive positive individuals potential benefits Protective Rapid Rapid diagnostic test Result RNA copies RNA copy RT-PCR SARS-CoV-2 SARS-COV-2 antigen testing sensitivity single-center specificity Swab symptomatic symptomatic patient Test the primary endpoint the SARS-CoV-2 Viral load WHO World Health Organisation yielding [DOI] 10.3390/jcm10102099 PMC 바로가기 [Article Type] Article
Convalescent plasma therapy and mortality in COVID-19 patients admitted to the ICU: a prospective observational studyResearch Published on 2021-05-122022-10-28 Journal: Annals of Intensive Care [Category] COVID-19, [키워드] 95% CI acute respiratory distress syndrome Admission association benefit convalescent plasma Convalescent plasma therapy coronavirus COVID-19 COVID-19 patient criteria Critically ill patient Exploratory analysis female hazard Horowitz ICU identify index intensive care invasive ventilation median median age Mortality non-invasive ventilation Patient plasma Probability prognostic variable prospective observational cohort prospective observational study receiving required Respiratory failure Result single-center supplementary material survival survival rates susceptible therapy Treatment treatment groups ventilatory support [DOI] 10.1186/s13613-021-00867-9 PMC 바로가기 [Article Type] Research
Pediatric liver and kidney transplantation in the era of COVID-19: a follow-up study from a tertiary referral center in IranCOVID-19 시대의 소아 간 및 신장 이식: 이란 3차 의뢰 센터의 후속 연구Research Published on 2021-05-112022-09-10 Journal: BMC Surgery [Category] SARS, 치료기술, [키워드] activity age Characteristics children cohort study complications Computed tomography conducted Course COVID-19 COVID-19 pandemic determine Donor effective evaluate favor Fever follow-up study GI symptoms hospital Hospitalization Hospitalized Influenza Iran kidney Kidney transplantation Laboratory laboratory result Laboratory results liver Liver transplantation malaise Negative PCR organ Organ transplant organ transplantation outcome Patient patients died PCR pediatric Pediatric case pediatric cases pediatrics positive positive PCR test Protective protocols radiologic recipients Result retrospective rhinorrhea screening method serologic test single-center supplementary material surgery Symptom the patient Transplant transplantation two patients [DOI] 10.1186/s12893-021-01226-y PMC 바로가기 [Article Type] Research
Race and ethnicity do not impact eligibility for remdesivir: A single-center experience인종과 민족은 렘데시비르에 대한 적격성에 영향을 미치지 않습니다: 단일 센터 경험Clinical Trial Published on 2021-05-062022-09-10 Journal: PLoS ONE [Category] SARS, 임상, 치료제, [키워드] benefit black Care clinical clinical trial clinical trials COVID-19 criteria Efficacy eligibility Enrollment ethnic group Ethnic groups Ethnicity evaluated examined exclusion criteria Health Health care Health care system Inclusion inclusion and exclusion criteria inclusion criteria Latinx medical record medications no difference Observational cohort study Older pandemic participant potential barrier potential barriers race Racial Remdesivir single-center therapy Treatment Trial white [DOI] 10.1371/journal.pone.0250735 PMC 바로가기 [Article Type] Clinical Trial
High Frequency of SARS-CoV-2 RNAemia and Association With Severe DiseaseSARS-CoV-2 RNA혈증의 높은 빈도 및 중증 질환과의 연관성Article Published on 2021-05-042022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adjusted Admission age all-cause mortality association Blood Care Clinical severity Comorbidities coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 cross-sectional cross-sectional study death demonstrated detectable detection determine diabetes Diabetes Mellitus examined Frequency Hospitalization hypertension ICU ICU admission implication individual Inpatient intensive care intensive care unit Invasive mechanical ventilation median age nasopharyngeal obesity occurred Older Outpatient outpatients patients plasma plasma sample plasma samples Prevalence prognostic prognostic indicator proportion reported required RNA RNAemia SARS CoV SARS CoV-2 SARS-CoV-2 SARS-CoV-2 RNA severe acute respiratory syndrome Coronavirus severe disease severity single-center strength undetectable utility variable was performed were assessed [DOI] 10.1093/cid/ciaa1054 PMC 바로가기 [Article Type] Article