Novel application of automated machine learning with MALDI-TOF-MS for rapid high-throughput screening of COVID-19: a proof of conceptCOVID-19의 신속한 고처리량 스크리닝을 위한 MALDI-TOF-MS를 사용한 자동화된 기계 학습의 새로운 적용: 개념 증명Article Published on 2021-04-152022-09-01 Journal: Scientific Reports [Category] MERS, SARS, 임상, 진단, 치료기술, [키워드] 2019 novel coronavirus Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 approach automated balance caused Chain Reaction clinical microbiology Combined comparable coronavirus COVID-19 COVID-19 testing detect diagnostic diagnostic testing evaluated exhibited exhibiting flight gold impacted Infectious disease Infectious-disease diagnostics machine machine learning mass spectrometry matrix ML model molecular nasal swab novel Novel coronavirus offer overcome pandemic PCR platform polymerase chain polymerase chain reaction positive residual respiratory reverse transcription RT-PCR SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 tests severe acute respiratory syndrome Coronavirus speed supply chains throughput Volunteer were used [DOI] 10.1038/s41598-021-87463-w PMC 바로가기 [Article Type] Article
Implementation of a COVID-19 surveillance programme for healthcare workers in a teaching hospital in an upper-middle-income country중상위 소득 국가의 교육 병원에서 의료 종사자를 위한 COVID-19 감시 프로그램 구현Research Article Published on 2021-04-142022-09-12 Journal: PLoS ONE [Category] MERS, SARS, 진단, [키워드] addition Characteristics collected Comorbidities Comorbidity component components conducted Contact tracing coronavirus disease cough country COVID-19 COVID-19 pandemic COVID-19 symptom COVID-19 testing cross-sectional analysis Daily described distribution female Fever had no Health healthcare healthcare worker Healthcare workers high risk highlight hospital implementation involved Laboratory majority Malaysia material moderate Mortality outbreak Outbreak investigation positive positive COVID-19 Prevalence reported symptoms Reporting Result risk Risk assessment Risk category Shortness of breath sore throat Surveillance Symptom symptomatic tested university were assessed with COVID-19 [DOI] 10.1371/journal.pone.0249394 PMC 바로가기 [Article Type] Research Article
COVID-19 in adults with dementia: clinical features and risk factors of mortality—a clinical cohort study on 125 patientsResearch Published on 2021-04-102022-10-28 Journal: Alzheimer's Research & Therapy [Category] COVID-19, MERS, [키워드] Admission age Alzheimer’s disease baseline behavioural Care cause Characteristics chronic clinical feature cohort study complications conducted Confirmed COVID-19 infection Confusion COVID COVID-19 COVID-19 testing CRP death delirium Dementia Desaturation disorder enrolled Evidence Factor Fall Fatality rate female Fever France hospitalised identify independent individual initial Kidney disease Logistic regression analysis Mortality MOST Novel coronavirus infection outcome Paris Patient patients Prognostic factors Prospective Study Result risk factor SARS-CoV-2 SARS-COV-2 infection survivor Symptom the disease Vascular was performed [DOI] 10.1186/s13195-021-00820-9 PMC 바로가기 [Article Type] Research
Urgent care center wait times increase for COVID-19 results in August 2020, with rapid testing availability limited2020년 8월에 COVID-19 결과에 대한 긴급 치료 센터 대기 시간이 증가하고 빠른 테스트 가용성이 제한됨Research Article Published on 2021-04-082022-09-10 Journal: BMC health services research [Category] MERS, SARS, 치료기술, [키워드] Access to care Accessibility Act Antigen average Care Chain Reaction changes in chi-square test chi-square tests collected conducted COVID-19 COVID-19 test COVID-19 testing Critical detect genetic material identify IMPROVE investigators lack majority methodology pandemic passage PCR PCR test polymerase chain polymerase chain reaction proportion reported Result room significant decrease significantly increased T-tests test results Urgent care center [DOI] 10.1186/s12913-021-06338-y PMC 바로가기 [Article Type] Research Article
Classification Models for COVID-19 Test Prioritization in Brazil: Machine Learning Approach브라질의 COVID-19 테스트 우선 순위 지정을 위한 분류 모델: 기계 학습 접근 방식Original Paper Published on 2021-04-082022-09-10 Journal: Journal of Medical Internet Research [Category] MERS, SARS, 진단, 치료기술, [키워드] Algorithm Algorithms Analysis analyzed applied Applying assist Brazil Brazilian chi-square test classification classification models Comparative analysis controlling coryza cough COVID-19 COVID-19 outbreak COVID-19 test COVID-19 testing criterion Decision tree disorder Dyspnea extreme feature Fever Friedman Gender headache Health highest inefficient Logistic regression machine machine learning medical diagnosis Metrics Model objective olfactory disorder olfactory disorders Patient problem problems random Random forest resources Result social distancing sore throat Statistical tests supervised learning Support support vector machine SVM symptomatic Test test prioritization was used [DOI] 10.2196/27293 PMC 바로가기 [Article Type] Original Paper
Ultra-sensitive Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Antigen Detection for the Diagnosis of Coronavirus Disease 2019 (COVID-19) in Upper Respiratory SamplesArticle Published on 2021-04-082023-07-01 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, [키워드] COVID-19 COVID-19 testing SARS-CoV-2 SARS-COV-2 antigen testing [DOI] 10.1093/cid/ciab063 PMC 바로가기
Social support, perceived risk and the likelihood of COVID-19 testing and vaccination: cross-sectional data from the United KingdomArticle Published on 2021-04-082022-10-31 Journal: Current Psychology (New Brunswick, N.j.) [Category] COVID-19, [키워드] COVID-19 COVID-19 pandemic COVID-19 testing cross-sectional examined help indirect effect individual likelihood loneliness MONITOR occur path analysis Perceived risk promote Self-efficacy Social support Support Testing United Kingdom vaccination [DOI] 10.1007/s12144-021-01681-z PMC 바로가기 [Article Type] Article
Early Tracheostomy in Morbidly Obese COVID-19 Patients: A Case Series and Discussion of Institutional PracticesOtolaryngology Published on 2021-04-072022-10-31 Journal: Cureus [Category] COVID-19, [키워드] Clinical outcome coronavirus disease COVID-19 COVID-19 patient COVID-19 testing Critically ill patient develop disease spread early phase Endotracheal intubation ENhance facilitate intensive care intubation management mechanical ventilation morbid obesity morbidly obese pandemic Patient patient population Practice Respiratory function Respiratory illness risk SARS-CoV-2 Sery tracheostomy unique ventilator [DOI] 10.7759/cureus.14345 PMC 바로가기 [Article Type] Otolaryngology
The relationship of large city out-of-hospital cardiac arrests and the prevalence of COVID-19Research Paper Published on 2021-04-072022-10-31 Journal: EClinicalMedicine [Category] COVID-19, [키워드] 9-1-1 affected aggregate average Cardiac arrest city collected COVID-19 COVID-19 testing dead Escalation European examined finding France functions funding highest increase Increases increases in involved Italy Local magnitude MOST New New York City Patient Prevalence prevalence of COVID-19 provided reflected reported returned Significant Spread United Kingdom [DOI] 10.1016/j.eclinm.2021.100815 PMC 바로가기 [Article Type] Research Paper
Virtualized clinical studies to assess the natural history and impact of gut microbiome modulation in non-hospitalized patients with mild to moderate COVID-19 a randomized, open-label, prospective study with a parallel group study evaluating the physiologic effects of KB109 on gut microbiota structure and function: a structured summary of a study protocol for a randomized controlled study입원하지 않은 경증에서 중등도의 COVID-19 환자에서 장내 미생물군유전체 조절의 자연사 및 영향을 평가하기 위한 가상화된 임상 연구 장내 미생물군 구조에 대한 KB109의 생리학적 효과를 평가하는 병렬 그룹 연구와 함께 무작위, 공개, 전향적 연구 및 기능: 무작위 대조 연구를 위한 연구 프로토콜의 구조화된 요약Letter Published on 2021-04-022022-09-10 Journal: Trials [Category] MERS, SARS, 임상, [키워드] 1:1 24 hours Ability absence addition adhere Affect age Ageusia allergy analysed Anosmia Anosmia/ageusia Antacid Antibiotics Antiviral assessment assigned Autoimmune disease Bariatric surgery baseline bilevel positive airway pressure Biomarker Biomarkers biomarkers of inflammation BiPAP Blinding blocker Blood blood sample Blood samples both groups bowel bowel resection breath Care care provider Cell change Chest chest tightness chills chronic lung disease cirrhosis clinical clinical study clinical trial Cold collected Community Comorbidity comparator Patients completion Compliance component computer Concomitant medication concomitant medications concurrent condition conducted contraindications coronavirus disease Coronavirus disease 2019 cough COVID-19 COVID-19 in patient COVID-19 symptom COVID-19 symptoms COVID-19 testing COVID-19-related symptom COVID-19-related symptoms COVID-19–related symptom COVID-19–related symptoms CPAP Cytokines D-dimer daily dose Day defined diarrhea dissemination drug duration of symptom Effect element eligible Enrollment evaluate evaluate the effect evaluated exacerbated exclusion criteria exploratory fatigue fatty Fatty acid feasible Female patients Fever fiber Follow-up follow-up period following group Gut gut microbiome gut microbiome composition gut microbiota headache Health Health care Health Care Utilization Health status healthcare Histamine history hospital Hospital admission Hospital admissions Hospitalization Hospitalized hypoxia Identifier IgM/IgG Immunity immunomodulatory immunosuppressive immunosuppressive therapy in both group include Infection Inflammation Inflammatory biomarker Inflammatory bowel disease information Informed consent inhibitors intake Interaction investigational agent irritable bowel syndrome KB109 Laboratory laboratory measures lactating library life Liver disease Lung disease magnitude malignancy management measure Measures medication medications Medicine metabolite Microbiome microbiota Mild mild to moderate Mild to moderate COVID-19 mild to moderate disease moderate Moderate COVID-19 moderate disease modulate modulation muscle pain nasal congestion neutralization assays not limited nucleic acid number objective Open-label opinion other compound other compounds outcome outcome measure Outpatient outpatients oxygen oxygen saturation Oxygen therapy Pain parallel group participant Participation Patient patient population Period Physical examination positive airway pressure Positive test Potential pre-symptomatic pregnant Primary outcome progression proportion proportions Prospective Study PROTECT protocol protocols proton pump provided pulse Pulse oximeter Quality of life Quantitative question randomisation randomised randomised controlled study randomization Randomized randomized controlled study receive recruitment reduction Registered reported response resting position risk risk of infection Sample size screened selected self-care sensitivities Sequencing serological serology shaking short-chain fatty acids Shortness of breath Sleep sleep apnea Smartphone sore throat specific biomarker specific biomarkers Spread SSC Standard Stool stratified Study design Study protocol study visit supplementary material Swab Symptom symptomatic patient Symptomatic patients Symptoms syndrome Tablet TEAEs Telemedicine telephone temperature the patient The United States therapy time Tolerability Treatment treatment-emergent adverse event undergo United States unlikely Viral Viral load water website worsening [DOI] 10.1186/s13063-021-05157-0 PMC 바로가기 [Article Type] Letter