Nature’s Role in Supporting Health during the COVID-19 Pandemic: A Geospatial and Socioecological StudyArticle Published on 2021-02-242022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, [키워드] Analysis applied benefit binomial regression models change changed collected data Community conducted confounding factors coronavirus correlation COVID-19 COVID-19 pandemic Deprivation driver England Evidence green space Health Human IMPROVE increase in information maintain majority measure Mental mental health conditions nature connectedness nature-based interventions pandemic Planetary health promote public health questionnaire response responses role significantly significantly more statistical analysis Supporting virus [DOI] 10.3390/ijerph18052227 PMC 바로가기 [Article Type] Article
The impact of interrupting enzyme replacement therapy in late-onset Pompe diseaseOriginal Communication Published on 2021-02-242022-10-29 Journal: Journal of Neurology [Category] Coronavirus, MERS, SARS, [키워드] 6MWT Administered adverse event adverse events autosomal recessive baseline calculated caused clinical assessment Clinical deterioration Clinical outcome COVID-19 pandemic Deterioration disease Disease progression disorder enzyme ERT fatigability FVC GAA Germany Glycogen storage disease type 2 impairment interruption Interruption of enzyme replacement therapy locomotor Measures MIP MRC Muscle strength muscles Mutation Patient patients performed Pompe disease prospective cohort study Pulmonary function Pulmonary function tests reduced reported Result Seven statistical analysis supplementary material Symptom therapy weakness [DOI] 10.1007/s00415-021-10475-z PMC 바로가기 [Article Type] Original Communication
Combined lymphocyte/monocyte count, D-dimer and iron status predict COVID-19 course and outcome in a long-term care facility결합된 림프구/단핵구 수, D-이량체 및 철 상태는 장기 요양 시설에서 COVID-19 경과 및 결과를 예측합니다Research Published on 2021-02-172022-09-10 Journal: Journal of Translational Medicine [Category] MERS, 바이오마커, [키워드] Admission Analysis Blood cells Care Clinical course Clinical outcome Combination Combined Concentration Course COVID-19 D-dimer dead patient decrease evaluated ferritin form generate Granulocytes groups hemoglobin Hospital stay identify IFR interleukin interleukin-6 iron Laboratory laboratory parameter Laboratory parameters Long-term care long-term care facilities lymphocyte Lymphocytes marker monocyte Multiorgan multiorgan disease outbreak outcome Platelets predict predictor Principal component principal component analysis progression Result severe pneumonia significantly Spread statistical statistical analysis subject survival was performed were used White blood cells [DOI] 10.1186/s12967-021-02744-2 PMC 바로가기 [Article Type] Research
Knowledge, Attitude, and Practices (KAPs) of Community Pharmacists Regarding COVID-19: A Cross-Sectional Survey in 2 Provinces of PakistanOriginal Research Published on 2021-02-162022-10-31 Journal: Disaster Medicine and Public Health Preparedness [Category] COVID-19, MERS, [키워드] 2019 coronavirus disease age analyzed Attitude Awareness Care category Community community pharmacists conducted counseling COVID-19 Cronbach’s alpha determinant effective global pandemic Good Health higher odd IBM Corp infections information KAPs study knowledge lockdown majority management Participants Pharmacist positive attitude Practice questionnaire reported social media SPSS statistical analysis survey therapy was used [DOI] 10.1017/dmp.2021.54 PMC 바로가기 [Article Type] Original Research
The COVID‐19 epidemic in Madagascar: clinical description and laboratory results of the first wave, march‐september 2020마다가스카르의 COVID-19 전염병: 2020년 3월-9월 첫 번째 물결의 임상 설명 및 실험실 결과Original Article Published on 2021-02-152022-09-10 Journal: Influenza and Other Respiratory Viruses [Category] MERS, SARS, 치료기술, [키워드] adjusted odds ratio age Asymptomatic clade clades collected confirmed cases Contact country COVID‐19 COVID‐19 database disease distribution Epidemic Epidemiology Europe First wave Genome highest independent individual Laboratory laboratory result limit madagascar mapped measure median age nasopharyngeal National Odds ratio oropharyngeal swab oropharyngeal swabs pandemic Patient patients positive positive patients Probability public health recommendation Result returned RT‐PCR sampling SARS‐CoV‐2 SARS‐CoV‐2 sequenced Spread statistical analysis strain subsequent Surveillance swabs tested the median viral strains virus viruses [DOI] 10.1111/irv.12845 PMC 바로가기 [Article Type] Original Article
On Drug-Membrane Permeability of Antivirals for SARS-CoV-2SARS-CoV-2에 대한 항바이러스제의 약물-막 투과성Article Published on 2021-02-112022-09-11 Journal: The journal of physical chemistry letters [Category] 치료제, [키워드] approach Behavior Bioavailability cellular organelles Characteristics Combination composed Compound contribute coronavirus determine drug drug design drugs effective drug effective drugs Efficacy endoplasmic reticulum membranes FIVE flexible Golgi highlight identify Interaction mammalian membrane membrane permeability membranes mitochondrial molecular dynamics Molecular dynamics simulation molecules negative correlation parameter permeability permeation plasma predict Proteins required SARS-CoV-2 Spike protein statistical analysis targets transmembrane variety Viral viral envelope [DOI] 10.1021/acs.jpclett.0c02397 PMC 바로가기 [Article Type] Article
Autopsy and statistical evidence of disturbed hemostasis progress in COVID-19: medical records from 407 patientsResearch Published on 2021-02-102022-10-29 Journal: Thrombosis Journal [Category] COVID-19, [키워드] activated Admission applied aPTT association Autopsy calculate change changes in Chinese Coagulation Combination Complete correlation COVID-19 COVID-19 infection COVID-19 patient Critical Critically ill patient D-dimer D-dimer level Deceased detect Diagnostic Criteria discharge disease severity Disseminated intravascular coagulation epidemiological evaluated Evidence GLU Glucose help Hemostasis Hospitalization ill patients indicated Infection late stage medical record Mild multiple organs National Health Commission NHC nonsurvivors objective parameter Patient patients patients with COVID-19 Platelet Pneumonia positive Prognosis progression Prothrombin time random reduced Result Severe patient severity severity of COVID-19 significantly Society statistical statistical analysis Statistics supplementary material Survivors the disease therapy thrombosis thrombotic [DOI] 10.1186/s12959-020-00256-5 PMC 바로가기 [Article Type] Research
Preexisting respiratory diseases and clinical outcomes in COVID-19: a multihospital cohort study on predominantly African American populationResearch Published on 2021-02-052022-10-28 Journal: Respiratory Research [Category] COVID-19, MERS, [키워드] 95% CI accounted adjusted Admission African African American age association BMI Cancer Chronic kidney disease Clinical outcome cohort study Comorbidities Comorbidity confounder confounders congestive heart failure Coronary artery disease correlation COVID-19 COVID-19 diagnosis COVID-19 patients Critical care determine diabetes dialysis died End-stage renal disease facilitate help hospital hyperlipidemia hypertension ICU ICU admission intensive care Laboratory Liver disease mechanical ventilation Mortality outcome outcomes Patient required resource Respiratory disease Result retrospective cohort study secondary severe disease Sex significantly higher smoking statistical analysis stroke Tobacco [DOI] 10.1186/s12931-021-01647-6 PMC 바로가기 [Article Type] Research
Evaluating Population Density as a Parameter for Optimizing COVID-19 Testing: Statistical AnalysisShort Paper Published on 2021-02-032022-10-29 Journal: Jmirx Med [Category] COVID-19, [키워드] Administered coronavirus correlation COVID-19 COVID-19 test COVID-19 testing density effective evade evaluate Evaluating increase Increased induce Infection Infectious diseases objective per capita performed Policy Population population density positive realignment reported Result risk SARS-CoV-2 SARS-CoV-2 transmission statistical analysis susceptible Test Testing virus widespread [DOI] 10.2196/22195 PMC 바로가기 [Article Type] Short Paper
Investigational Treatments for COVID-19 may Increase Ventricular Arrhythmia Risk Through Drug InteractionsCOVID-19에 대한 조사 치료는 약물 상호 작용을 통해 심실 부정맥 위험을 증가시킬 수 있습니다Article Published on 2021-02-012022-09-11 Journal: CPT: pharmacometrics & systems pharmacology [Category] 치료제, [키워드] action potential Analysis Arrhythmias Azithromycin cardiac adverse event cardiac adverse events cardiac electrophysiology caused cellular Chloroquine Combination combination therapy coronavirus disease Coronavirus disease 2019 COVID-19 disease drug drug combination drug combinations Drug interactions drugs Effect Factor greater healthy individual healthy individuals heart disease heart failure increase Isolation lead Lopinavir mathematical men molecular Myocyte Patient patient group pharmacokinetics potential benefits predict predicted QT prolongation Quantitative reported risk Ritonavir Sex Simulation statistical analysis susceptible Therapies treat Treatment ventricular ventricular arrhythmias women [DOI] 10.1002/psp4.12573 PMC 바로가기 [Article Type] Article