Factors associated with peritraumatic stress symptoms among the frontline healthcare workers during the outbreak of COVID-19 in China중국에서 COVID-19 발생 시 최전선 의료 종사자의 외상성 스트레스 증상과 관련된 요인Article Published on 2022-01-112022-09-11 Journal: BMJ Open [Category] SARS, 치료기술, 치료제, [키워드] Characteristics China clinically Combined Comprehensive conducted contributing to correlated COVID-19 demographic Depression depression & difficulty Early detection Emergency emotional Emotional exhaustion expected Factor Factors frontline healthcare worker HCW HCWs Health health & healthcare worker help higher risk Infection Intervention investigated less lowest Measures mood disorders MOST outbreak physical Physical symptom physical symptoms Post-traumatic stress disorder Prevalence Psychological psychological symptom PTSD public health questionnaire receipt reducing regression analysis Safety scored shown significantly Social support stress symptom Support Symptoms tension venting working [DOI] 10.1136/bmjopen-2020-047753 PMC 바로가기 [Article Type] Article
When stem cells meet COVID-19: recent advances, challenges and future perspectivesReview Published on 2022-01-102022-10-29 Journal: Stem Cell Research & Therapy [Category] COVID-19, SARS, [키워드] acute respiratory distress approaches caused Cell clinically Coronavirus disease 2019 COVID-19 COVID-19 pandemic develop disease effective global public health hypoxic respiratory failure lack Mortality MSCs multiple organ failure Organoid models Perspective provide rate of infection Research Respiratory Coronavirus SARS-CoV-2 stem cell Stem cell therapy Stem cell threapy supportive care syndrome systematic review Therapies Treatment [DOI] 10.1186/s13287-021-02683-1 PMC 바로가기 [Article Type] Review
Ultraviolet-C Irradiation, Heat, and Storage as Potential Methods of Inactivating SARS-CoV-2 and Bacterial Pathogens on Filtering Facepiece RespiratorsArticle Published on 2022-01-102022-10-28 Journal: Pathogens [Category] COVID-19, [키워드] Acinetobacter applied Bacteria clinically clinics COVID-19 COVID-19 pandemic Disinfection dose dry heat Efficacy evaluate heat High dose hospital inoculated irradiation kill Local mimicking multidrug-resistant New New Zealand pathogen Personal protective equipment planktonic Potential PPE Pseudomonas aeruginosa reducing replication-competent SARS-CoV-2 Respirator reuse robust salivary SARS-CoV-2 SARS-CoV-2 replication Staphylococcus aureus storage temperature Treatment triggered UV-C virus [DOI] 10.3390/pathogens11010083 PMC 바로가기 [Article Type] Article
Cytokine Hemoadsorption as Rescue Therapy for Critically Ill Patients With SARS-CoV-2 Pneumonia With Severe Respiratory Failure and HypercytokinemiaMedicine Published on 2022-01-102022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] “cytokine storm” acute respiratory distress syndrome (ARDS) All the patient analyzed benefit Berlin C-reactive protein Case series clinical response clinically coronavirus 2019 disease COVID-19 Critically ill patient cytokine cytokine removal D-dimer death dysregulated Europe evaluate failure ferritin Germany hemoadsorption high risk hypercytokinemia ICU identifying IL-6 Ill improvement in-hospital mortality inflammatory biomarkers Inflammatory response intensive care interleukin-6 Invasive mechanical ventilation organ dysfunction Oxygenation PaO pathophysiology Patient plasma Prone position prone positioning reduction in rescue respiratory Respiratory failure Retrospective study SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pneumonia severe respiratory failure significant difference single center SOFA score Therapies therapy Treatment with COVID-19 [DOI] 10.3389/fmed.2021.779038 PMC 바로가기 [Article Type] Medicine
MCMV-based vaccine vectors expressing full-length viral proteins provide long-term humoral immune protection upon a single-shot vaccination전장 바이러스 단백질을 발현하는 MCMV 기반 백신 벡터는 단회 백신 접종 시 장기간 체액성 면역 보호를 제공합니다Article Published on 2022-01-072022-09-12 Journal: Cellular and Molecular Immunology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] acute respiratory syndrome antigenic peptide caused CD8 Cellular immune response cellular immunity clinically CMV coronavirus cytomegalovirus Effect elicit excluded expressing full-length humoral humoral imunity Humoral response immune protection immune response Immunological memory induce Influenza influenza A virus Influenza virus injection investigated medical need memory T cells mice morbidity and mortality murine neutralizing antibody responses Pandemics Pathogens Population Protective Protein public health Respiratory pathogens robust SARS-CoV-2 T cell the spike protein vaccination Vaccine vaccine vector Vaccines vector Viral protein [DOI] 10.1038/s41423-021-00814-5 PMC 바로가기 [Article Type] Article
Analytical and Clinical Evaluation of the Semiquantitative Elecsys Anti-SARS-CoV-2 Spike Protein Receptor Binding Domain Antibody Assay on the Roche cobas e602 AnalyzerRoche cobas e602 분석기에서 반정량적 Elecsys Anti-SARS-CoV-2 스파이크 단백질 수용체 결합 도메인 항체 분석의 분석 및 임상 평가Article Published on 2022-01-062022-09-11 Journal: American journal of clinical pathology [Category] SARS, 진단, 치료기술, 치료법, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus Analyzer Anti-spike anti-spike antibodies antibodies antibody Bilirubin Biotin clinical clinically Concordance coronavirus COVID-19 COVID-19 patient COVID-19 vaccination cross-reactivity detect diagnostics Elecsy ELISA enzyme-linked immunosorbent enzyme-linked immunosorbent assay evaluate evaluated exhibit greater hemoglobin IgA antibodies IgA antibody IgG IgM immunoassay Interference Lateral flow device linearity measure mRNA Neutralization assay PCR positivity plasma Precision Protein Receptor binding domain respiratory robust Roche SAR-CoV-2 SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike protein SARS-CoV-2 virus Semiquantitative semiquantitatively Sensitivity and specificity serology Seropositivity serum spike Spike protein triglycerides turn [DOI] 10.1093/ajcp/aqab092 PMC 바로가기 [Article Type] Article
Comprehensive Flow Cytometry Profiling of the Immune System in COVID-19 Convalescent IndividualsCOVID-19 회복기 개인의 면역 체계에 대한 포괄적인 유세포 분석 프로파일링Immunology Published on 2022-01-062022-09-12 Journal: Frontiers in Immunology [Category] 진단, [키워드] alteration analysed Analysis Asymptomatic B-cell cells circulating clinically Comprehensive COVID-19 days post-infection deaths develop dysregulation Flow flow cytometry follicular follicular dendritic cell functional healthy controls healthy donors immune immune dysregulation immune system Immunoglobulin individual individuals induce infected with SARS-CoV-2 innate cell marker Mild Pathologies performed Post-infection Profiling Prognosis Re-infection recovered COVID-19 patient risk factor Sample SARS-CoV-2 subset Symptom System T-cell unsupervised algorithms [DOI] 10.3389/fimmu.2021.793142 PMC 바로가기 [Article Type] Immunology
Genomic Surveillance Enables the Identification of Co-infections With Multiple SARS-CoV-2 Lineages in Equatorial Guinea게놈 감시를 통해 적도 기니에서 여러 SARS-CoV-2 계통과의 동시 감염 식별 가능Case Reports Published on 2022-01-042022-09-11 Journal: Frontiers in Public Health [Category] MERS, SARS, 변종, 유전자 메커니즘, [키워드] activities activity addition Asymptomatic Beta caused Central-Africa clinically Co-infection COVID-19 COVID-19 disease Delta Delta VOC epidemiological situation Equatorial Guinea Evolution Genetic genetic recombination Genomic surveillance global public health identification immune evasion island knowledge Multiple National Public public health Rapid Recombination response resulting SARS-CoV-2 SARS-CoV-2 genomic surveillance SARS-CoV-2 lineage SARS-CoV-2 variant SARS-CoV-2 variants Spread Surveillance the SARS-CoV-2 Transmission variant of concern VoC [DOI] 10.3389/fpubh.2021.818401 PMC 바로가기 [Article Type] Case Reports
Development of RNA-Based Assay for Rapid Detection of SARS-CoV-2 in Clinical SamplesArticle Published on 2022-01-012022-11-15 Journal: Intervirology [Category] SARS, 치료기술, 치료제, [키워드] acute respiratory syndrome aggregation caused clinical clinical sample clinically Colorimetric test Community coronavirus coronavirus disease Coronavirus disease-19 COVID-19 COVID-19 negative detect detection Detection limit development diagnosed Diagnosis gold standard include less management nasopharyngeal optical outbreak pandemic pandemic coronavirus platform polymerase chain positive COVID-19 Rapid retained Ribonucleic acid RNA sample RNA-dependent RNA polymerase Sample SARS-CoV-2 SARS-CoV-2 RNA sensitivity specificity Spread subject women [DOI] 10.1159/000522337 PMC 바로가기
A smartphone-based visual biosensor for CRISPR-Cas powered SARS-CoV-2 diagnosticsCRISPR-Cas 기반 SARS-CoV-2 진단을 위한 스마트폰 기반 시각 바이오센서Article Published on 2022-01-012022-09-11 Journal: Biosensors & bioelectronics [Category] SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 aggregation applied changes clinical clinical samples clinically color coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 CRISPR CRISPR-Ca CRISPR-Cas12a cross-reactivity Degradation detect develop diagnostics evidenced eye gold Gold nanoparticle Gold nanoparticles imperative limit of detection nucleic acid nucleic acids pandemic positive provide provided pseudovirus pseudoviruses qPCR RNA robust SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 pseudoviruses selective single-stranded DNA Smartphone Smartphone-based diagnostics the SARS-CoV-2 transcribed triggered vectors Visual Visual biosensor. [DOI] 10.1016/j.bios.2021.113646 PMC 바로가기 [Article Type] Article