Differences in Clinical Features and Laboratory Results between Adults and Children with SARS-CoV-2 InfectionComparative Study Published on 2020-12-012022-10-27 Journal: BioMed Research International [Category] COVID-19, MERS, SARS, [키워드] accounted acute respiratory syndrome Adults analyzed aspartate Aspartate aminotransferase Asymptomatic asymptomatic infection cause Characteristics Chest computed tomography Chest CT chest CT examination children clinical Clinical characteristics clinical information Clinical symptoms Clustering coronavirus COVID-19 determine difference epidemiological increased risk infected with SARS-CoV-2 Infection Laboratory Liver damage lymphocyte Lymphocytes Manifestations Mild neutrophil not significantly different Patient performed Platelet positive Prevalence proportion reduction Result SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 nucleic acid significantly higher [DOI] 10.1155/2020/6342598 PMC 바로가기 [Article Type] Comparative Study
Ultra-Sensitive Serial Profiling of SARS-CoV-2 Antigens and Antibodies in Plasma to Understand Disease Progression in COVID-19 Patients with Severe Disease중증 질환이 있는 COVID-19 환자의 질병 진행을 이해하기 위한 혈장 내 SARS-CoV-2 항원 및 항체의 초민감 직렬 프로파일링Article Published on 2020-12-012022-09-11 Journal: Clinical Chemistry [Category] MERS, SARS, 진단, 치료기술, 치료법, [키워드] 95% CI acute respiratory syndrome acute respiratory syndrome coronavirus analyzed anti-SARS-CoV-2 Antigen Biomarker Blood changes in clearance clinical outcomes Clustering Combined Concentration coronavirus coronavirus disease COVID-19 COVID-19 case COVID-19 negative COVID-19 positive patients detect detectable Disease progression Hierarchical hierarchical clustering ICU admission identify Infection intubation longitudinal plasma samples molecule MONITOR N antigen nasopharyngeal nucleocapsid antigen nucleocapsid antigens Patient patients patients with COVID-19 PCR plasma plasma sample positive positive result Profiling quantified reported respiratory Respiratory failure RT-PCR test S1 subunit SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 S1 SARS-CoV-2 spike SARS-CoV-2 viral Seroconversion serological serological assays serology tests severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severe disease Simoa single molecule arrays statistically significant test results These data Viral Viral antigen viral antigens [DOI] 10.1093/clinchem/hvaa213 PMC 바로가기 [Article Type] Article
Population-based seroprevalence of SARS-CoV-2 and the herd immunity threshold in MaranhãoSARS-CoV-2의 인구 기반 혈청 유병률 및 Maranhão의 집단 면역 역치Original Article Published on 2020-11-272022-09-10 Journal: Revista de Saúde Pública [Category] MERS, SARS, 진단, 치료기술, [키워드] 95%CI Adults antibody Asymptomatic best Brazil Clustering Coronavirus infections death electrochemiluminescence immunoassay estimate Fatality rate herd immunity Herd immunity threshold highest Household survey IFR IgG antibodies IgM and IgG Immunity, Herd individual Infection Intervention knowledge Local men Mortality Older Older adults pandemic physical distancing Population Qualitative qualitative detection reached reported Roche Diagnostics SARS-CoV-2 SARS-COV-2 infection Seroepidemiologic studies Seroprevalence significantly lower Stratification total antibodies total antibody was performed [DOI] 10.11606/s1518-8787.2020054003278 PMC 바로가기 [Article Type] Original Article
Spatial analysis of COVID-19 spread in Iran: Insights into geographical and structural transmission determinants at a province levelResearch Article Published on 2020-11-182022-10-28 Journal: PLoS Neglected Tropical Diseases [Category] COVID-19, SARS, [키워드] Adults affected affecting Analysis applied approach association associations autocorrelation average Bayesian Characteristics Cluster Clustering Compliance concerning correlated country COVID-19 COVID-19 case COVID-19 cases COVID-19 outbreak cumulative death decrease determinant disease distribution Epidemiology Factor feature greater Health health information identify impacted information insight Iran less Local Older older population Physicians populations predict public health measures quartile rapid increase reduce Region reported representing SARS-CoV-2 significantly higher social distancing Sociodemographic factor Spread statistical Structure susceptible Tehran temperature the disease Transmission variable [DOI] 10.1371/journal.pntd.0008875 PMC 바로가기 [Article Type] Research Article
Clinical, regional, and genetic characteristics of Covid-19 patients from UK BiobankUK Biobank의 코로나19 환자의 임상적, 지역적, 유전적 특성Research Article Published on 2020-11-172022-08-13 Journal: PLoS ONE [Category] MERS, SARS, 유전자 메커니즘, [키워드] 95% CI adjusted adjusted relative risk Adjusting analyzed angiotensin angiotensin converting enzyme association baseline black Black race Blood blood type Blood types Characteristics chronic obstructive chronic obstructive pulmonary disease clinical Clinical risk factors Clustering Comorbidities conducted coronavirus disease Coronavirus disease 2019 Depression Deprivation determined by discrimination disease severity Effect enzyme Evidence Factor Factors feature Genetic genetic factors Genetic variant genetic variants group heart disease higher risk include increase in increased risk indication individual individuals information inhibitor ischemic heart disease Laboratory limitation Local loci longitudinal cohort study main outcome measure Meta-analysis obstructive pulmonary disease Odds ratio participant Participants Patient patients with comorbidity Poisson regression positive positive status Positive test prospective cohort study provided pulmonary disease Racial recent recruited reduced Relative risk Research Result risk risk factor robust rs8176719 significantly increased Standard deviation test results tested UK biobank United Kingdom white zone [DOI] 10.1371/journal.pone.0241264 PMC 바로가기 [Article Type] Research Article
Computational Identification of Human Biological Processes and Protein Sequence Motifs Putatively Targeted by SARS-CoV-2 Proteins Using Protein-Protein Interaction NetworksArticle Published on 2020-11-062023-07-06 Journal: Journal of Proteome Research [Category] SARS, [키워드] Clustering COVID-19 enrichment analysis Gene ontology Graph theory motif discovery protein−protein interaction network SARS-CoV-2 Statistics [DOI] 10.1021/acs.jproteome.0c00422 PMC 바로가기
Surveillance Routing of COVID-19 Infection Spread Using an Intelligent Infectious Diseases AlgorithmComputational and Artificial Intelligence Published on 2020-11-052022-10-30 Journal: Ieee Access [Category] COVID-19, [키워드] affected Algorithm applied Care Cluster Clustering Computational intelligence Concentration coronavirus disease Coronavirus disease 2019 (COVID-19) COVID-19 COVID-19 cases deaths decrease group groups hazard Health highest hospital identify Infection infection rate Infectious disease information KDE kernel density estimation (KDE) medical care routing New York number of infected optimization prevented reduce reported resource Routing Spread survival rate virus was determined [DOI] 10.1109/ACCESS.2020.3036347 PMC 바로가기 [Article Type] Computational and Artificial Intelligence
Epidemiological Characteristics and Clinical Features of Patients Infected With the COVID-19 Virus in Nanchang, Jiangxi, ChinaMedicine Published on 2020-11-042022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] 2019 novel coronavirus analyses Asymptomatic biochemical biochemical & physiological biomarkers China chronic liver disease clearance clinical clinical information clinical manifestations close contact Clustering conditions correlated cough COVID-19 COVID-19 pandemic COVID-19 virus Critical CRP CT scan cytokine cytokine level Cytokines demographics disease dominant epidemiogy Epidemiology ESR fatigue Fever ground-glass opacity had no hypertension IgG IL-10 IL-4 IL-6 information initial investigated Laboratory laboratory result lymphocyte lymphocyte counts median age moderate Most patient outcomes pandemic Patient patients percentages Physical examination public health radiological retrieved Symptom Symptoms the mean TNF-α Treatment underlying conditions viral nucleic acid while women Wuhan [DOI] 10.3389/fmed.2020.571069 PMC 바로가기 [Article Type] Medicine
Epidemiological features and viral shedding in children with SARS-CoV-2 infectionSARS-CoV-2 감염 아동의 역학적 특징 및 바이러스 배출Multicenter Study Published on 2020-11-012022-09-11 Journal: Journal of medical virology [Category] SARS, 치료기술, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 age Antiviral antiviral therapy Asymptomatic children China clearance close contact Clustering conducted Contact coronavirus disease Coronavirus disease 2019 Coronavirus-2 COVID-19 Effect epidemiological Epidemiological characteristics epidemiological data evaluated Families feature fecal group Hospitalization Incubation period indication Infection Kaplan-Meier mean incubation period Mild symptom mild symptoms multicenter multicenter study not different not used pandemic Pediatric case Pediatric patient Pediatric patients Pneumonia positive quarantine respiratory retrospective reverse transcription PCR RNA SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RNA SARS-CoV-2 RNA detection severe acute respiratory syndrome Coronavirus significantly lower subsequent susceptibility the SARS-CoV-2 treated Viral viral clearance viral excretion. viral shedding Zhejiang [DOI] 10.1002/jmv.26180 PMC 바로가기 [Article Type] Multicenter Study
Loneliness during a strict lockdown: Trajectories and predictors during the COVID-19 pandemic in 38,217 United Kingdom adultsArticle Published on 2020-11-012022-10-29 Journal: Social science & medicine (1982) [Category] Coronavirus, SARS, [키워드] age analysed Analysis baseline changed Clustering collecting data coronavirus COVID COVID-19 COVID-19 pandemic decrease effort Factor Gender geographical location greater growth trajectories growth trajectory Health highest identify inactive lockdown loneliness longitudinal lowest measure mental health mental health condition objective pandemic Perceived predictor predictors profile proportion Protective public health rationale Result risk factor Seven slight increase Social factor Support Trajectories trajectory two groups UCL United Kingdom was used women [DOI] 10.1016/j.socscimed.2020.113521 PMC 바로가기 [Article Type] Article