Comparative Genomic Analysis of Classical and Variant Virulent Parental/Attenuated Strains of Porcine Epidemic Diarrhea VirusArticle Published on 2015-10-232022-10-28 Journal: Viruses [Category] Coronavirus, [키워드] aa deletion Amino acid analyzed Cell changes in characteristic characterized classical Comparative epidemic diarrhea etiological agent Genomic analysis marker molecular basis mutations N protein non-structural protein nsp10 nucleotide Open reading frame ORF ORF3 outbreak parental passage passages PEDV responsible S protein sequence sequenced strain Strains synonymous variant variant PEDV Variation Vero Cell virus virus attenuation virus cell adaptation [DOI] 10.3390/v7102891 PMC 바로가기 [Article Type] Article
Comparative In Vivo Analysis of Recombinant Type II Feline Coronaviruses with Truncated and Completed ORF3 RegionResearch Article Published on 2014-02-202022-10-28 Journal: PLoS ONE [Category] Coronavirus, MERS, [키워드] absence approach biological property caused Characteristics Comparative Completed coronavirus Course experiment febrile Genetic Gut in vitro in vivo Infection Intensive intestine nucleotides ORF3 recombinant Region regions Replication responsible serological response Seven significantly lower the disease Type Viremia virulent virus Virus neutralization viruses while [DOI] 10.1371/journal.pone.0088758 PMC 바로가기 [Article Type] Research Article
In-vitro renal epithelial cell infection reveals a viral kidney tropism as a potential mechanism for acute renal failure during Middle East Respiratory Syndrome (MERS) Coronavirus infectionShort Report Published on 2013-12-232022-10-28 Journal: Virology Journal [Category] Coronavirus, MERS, [키워드] acute renal failure Angiotensin-converting-enzyme-2 ARF benefit bronchial epithelial cell bronchial epithelial cells Case report cause Cell cell type cells cellular receptor Characteristics Comparative description Dipeptidyl-peptidase-4 epithelial epithelial cell epithelial cells experiment explain finding histological staining human coronavirus human kidney impairment individual Infected Infection infections infectious kidney kidney infection median time MERS MERS patient MERS-CoV Middle East Middle East respiratory syndrome occurred Patient peer-reviewed potential mechanism produced progeny renal Renal epithelial cells Replication respiratory reveal SARS patients SARS- and MERS-CoV SARS-CoV SD severe staining Symptom systematic review Transmission Treatment Urine [DOI] 10.1186/1743-422X-10-359 PMC 바로가기 [Article Type] Short Report
The Evolution of the Anopheles 16 Genomes Project모기속 16 유전체 프로젝트의 진화Investigation Published on 2013-07-012024-08-13 Journal: G3: Genes|Genomes|Genetics [Category] 말라리아, [키워드] assembly collaboration Comparative malaria vector [DOI] 10.1534/g3.113.006247 PMC 바로가기 [Article Type] Investigation
Comparative Genomics of Korean Infectious Bronchitis Viruses (IBVs) and an Animal Model to Evaluate Pathogenicity of IBVs to the Reproductive OrgansArticle Published on 2012-10-302022-10-28 Journal: Viruses [Category] Coronavirus, [키워드] Amino acid Analysis animal animal model applied backbone Comparative Comparative genomics control group different Efficacy Gene Genome genomic Genomics Genotype IBV identity inactivated Infection Infectious Bronchitis Virus inhibited Korean lesions Massachusett maturation Model nucleotide ovarian ovarian follicle formation oviduct pathogenicity recombinant virus Recombination reproductive organ strain Vaccine virus was performed [DOI] 10.3390/v4112670 PMC 바로가기 [Article Type] Article
Comparative and Functional Genomics of Rhodococcus opacus PD630 for Biofuels Development바이오연료 개발을 위한 Rhodococcus opacus PD630의 비교 및 기능 유전체학Research Article Published on 2011-09-082022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] accumulate accurate Actinomycetale Analysis approach assigned Author Bacteria bacterium Biofuel carbon catabolic cellular Comparative Comparative analysis Complete compounds conserved development dry weight Engineering Enzymes eukaryotic Fatty acid fatty acids Gene gene family Genetic Genome genome sequence Genomics growth homologous homologous genes identify implicated included information led to lipid metabolism metabolic product metabolism multidisciplinary approach Pathways performed phenotypic phenotypic information Phylogenetic analysis predicted gene provide provided reaction related Research screened sequenced substrate substrates Support target gene Target genes triacylglycerol working model [DOI] 10.1371/journal.pgen.1002219 PMC 바로가기 [Article Type] Research Article
Comparative Pathogenesis of Three Human and Zoonotic SARS-CoV Strains in Cynomolgus MacaquesResearch Article Published on 2011-04-202022-10-28 Journal: PLoS ONE [Category] Coronavirus, Fulltext, 조류인플루엔자, [키워드] acute respiratory syndrome against SARS-CoV change characterized Comparative compared Critical disease cynomolgus macaque Disease model Efficacy Epidemic exacerbated function Gene Heterologous histopathological Host host gene host response Human infect Infected Infection interferon signaling isolates macaque majority Mild pathogen pathogenicity pathway Pathways Prevent radiological regulated Replication SARS-CoV significant difference strain Strains subsequent therapeutic strategy Transmission Vaccine while zoonotic [DOI] 10.1371/journal.pone.0018558 PMC 바로가기 [Article Type] Research Article
Comparative Anti-Infectious Bronchitis Virus (IBV) Activity of (-)-Pinene: Effect on Nucleocapsid (N) ProteinArticle Published on 2011-01-252022-10-30 Journal: Molecules [Category] Coronavirus, [키워드] (-)-pinene active site activity anti-IBV activity binding energy Cell Comparative Compound Concentration determined docking Effect found IBV indicated Infectious Bronchitis Virus ingredient inhibit molecular MTT N terminus nucleocapsid occur penetration phosphorylated Protein Result TD virus [DOI] 10.3390/molecules16021044 PMC 바로가기 [Article Type] Article
Complete genomic sequence analysis of infectious bronchitis virus Ark DPI strain and its evolution by recombinationShort Report Published on 2008-12-222022-10-28 Journal: Virology Journal [Category] Coronavirus, MERS, [키워드] 3CL pro Analysis analyzed circulating Comparative compared coronavirus Coronaviruses different DPI Evolution found Genes Genome genomic RNA genomic sequence Gray IBV identity Infectious Bronchitis Virus intergenic region nucleotides occur occurred open reading frames other coronavirus Point mutation polymerase Possible proteinase RdRP Recombination recombination event sequence Sequence analysis sequenced similarity spike gene strain Strains UTR virulent [DOI] 10.1186/1743-422X-5-157 PMC 바로가기 [Article Type] Short Report