The scale and dynamics of COVID-19 epidemics across Europe1001 Published on 2020-11-252022-10-28 Journal: Royal Society Open Science [Category] COVID-19, [키워드] Contact coronavirus country COVID-19 death death rate develop Epidemic Epidemics Epidemiology Europe European country expected flexible growth individuals Infection intrinsic intrinsically lockdown modelling peaked populations reported susceptible Transmission [DOI] 10.1098/rsos.201726 PMC 바로가기 [Article Type] 1001
Multiepitope Subunit Vaccine Design against COVID-19 Based on the Spike Protein of SARS-CoV-2: An In Silico AnalysisResearch Article Published on 2020-11-192022-10-29 Journal: Journal of Immunology Research [Category] COVID-19, MERS, SARS, [키워드] activity acute respiratory syndrome Analysis association candidate vaccine caused cholera complex conducted coronavirus COVID-19 COVID-19 disease develop EAAAK linker epitope Epitopes feasible flexible globe GPGPG linkers Health HLA hydrogen bonds in vitro experiment in vivo Interaction molecular docking analysis multiepitope vaccine N-terminus positive protective immunity Safe SARS-CoV-2 sequence spike glycoprotein stability subunit suggested Support the Spike the vaccine toxin Vaccine was performed [DOI] 10.1155/2020/8893483 PMC 바로가기 [Article Type] Research Article
Antibody profiling and prevalence in US patients during the SARS-CoV2 pandemicResearch Article Published on 2020-11-192022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] Accuracy affected analyzed antibody Antibody Response binding domain clinical sensitivity collected detect Developing diagnostics disease detection flexible glycoprotein handling IgA IgG IgM immune response Immunity imperative methodology Microarray microbial minimum multiplex novel antigen Novel coronavirus NP swab nucleoprotein outbreak pandemic Pandemics Patient platform Prevalence processed Protein RBD reliability Result risk RT-PCR SARS-CoV2 Sensitivity and specificity serum serum samples specificity spot SST Variation virus Volume was used [DOI] 10.1371/journal.pone.0242655 PMC 바로가기 [Article Type] Research Article
Analysis of vitamin D level among asymptomatic and critically ill COVID-19 patients and its correlation with inflammatory markers무증상 코로나19 환자 및 중증 코로나19 환자의 비타민 D 수치 및 염증 지표와의 상관관계 분석Observational Study Published on 2020-11-192022-09-10 Journal: Scientific Reports [Category] 바이오마커, 임상, 치료법, [키워드] administration Affect age approach approval Asymptomatic Asymptomatic COVID-19 characterized Clinical severity college Concentration correlation COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 patients Critically ill current deficiency disease severity endocrinology enrolled ethics committee Factor Fatality rate ferritin flexible group Health care ICU admission IL-6 increased mortality Inflammatory marker inflammatory markers Inflammatory response Microbiology observational study participant Patient patients population at risk Prevalence prospective observational study risk Risk factors serum Serum ferritin Serum IL-6 Serum level severe COVID-19 patients severely ill patient severely ill patients severity Standard statistical analysis study period the disease TNFα translate Variability Vitamin D vitamin D deficiency vitamin D level vitamin D supplement vitamin D supplements was performed were measured [DOI] 10.1038/s41598-020-77093-z PMC 바로가기 [Article Type] Observational Study
Highly Versatile Cloud-Based Automation Solution for the Remote Design and Execution of Experiment Protocols during the COVID-19 PandemicCOVID-19 팬데믹 기간 동안 실험 프로토콜의 원격 설계 및 실행을 위한 다목적 클라우드 기반 자동화 솔루션Special Collection: Advances in Technology to Address COVID-19 Published on 2020-11-192022-09-01 Journal: Slas Technology [Category] MERS, SARS, 진단, [키워드] accelerate addition approach Automation benefit bottleneck clinical trials cloud-based laboratory software connected lab COVID-19 diagnostics events example faster flexible group implication Informed involved lab automation Laboratory lockdown Measures Mutation new frontier pathology pipetting robot private sector protocol remote required Research respond social distancing solution switching the disease unique use case Vaccine virus [DOI] 10.1177/2472630320971218 PMC 바로가기 [Article Type] Special Collection: Advances in Technology to Address COVID-19
Engineered ACE2 receptor traps potently neutralize SARS-CoV-2Biological Sciences Published on 2020-11-102022-10-29 Journal: Proceedings of the National Academy of Sciences of [Category] COVID-19, [키워드] ACE2 ACE2 receptor ACE2 variant acute respiratory syndrome addition Affinity maturation amino acid change Angiotensin-converting enzyme antibody antiviral therapeutics approach authentic SARS-CoV-2 virus backbone binding cells computational design convalescent patient Convalescent patients coronavirus Coronaviruses COVID-19 pandemic domain entry receptor faster flexible generate half-maximal inhibitory concentration host cells human immunoglobulin IC50s impair inactivated Infection infections lentivirus mechanism mutations neutralize neutralized neutralizing antibody offer other coronavirus Prevent Protein random mutagenesis RBD receptor Receptor binding Receptor binding domain receptor protein receptor trap respiratory diseases SARS-CoV-1 SARS-CoV-2 SARS-CoV-2 entry SARS-COV-2 infection Seven Significance the RBD therapeutic response treat variant viral entry viral escape Viral resistance viral spike protein virus wild-type yeast yeast display [DOI] 10.1073/pnas.2016093117 PMC 바로가기 [Article Type] Biological Sciences
Personality Disorders in Time of PandemicPersonality Disorders (K Bertsch, Editor) Published on 2020-11-102022-10-31 Journal: Current Psychiatry Reports [Category] Coronavirus, SARS, [키워드] adopted affected Anxiety borderline personality disorder Cluster Compliance Contagion COVID-19 Diagnosis disorder Effect Epidemic Evidence feature finding flexible hypotheses less measure mental health pandemic Pandemics pathology Patient Personality Personality disorders Psychological Psychological outcomes quarantine reaction recent review social distancing starting point Stress therapeutic strategy time [DOI] 10.1007/s11920-020-01204-w PMC 바로가기 [Article Type] Personality Disorders (K Bertsch, Editor)
How does a (Smart) Age-Friendly Ecosystem Look in a Post-Pandemic Society?Article Published on 2020-11-092022-10-29 Journal: International Journal of Environmental Research an [Category] Coronavirus, SARS, [키워드] age in place aging approach benefit can be used changes in Cohort Community coronavirus COVID-19 design hacking Digital domain E-health Ecology ecosystem eight Factor flexible gerontechnology greater Health human-centered design impacted improvement Internet of Things limitation Older adults outlined pandemic Population populations positive Research respond shown SmaRT smart cities smart ecosystem technology the WHO urban planning [DOI] 10.3390/ijerph17218276 PMC 바로가기 [Article Type] Article
KG-COVID-19: A Framework to Produce Customized Knowledge Graphs for COVID-19 ResponseArticle Published on 2020-11-092022-10-04 Journal: Patterns [Category] 신약개발, [키워드] applied Biomedical research Clinicians Community COVID-19 COVID-19 knowledge COVID-19 pandemic database downstream DSML 3: Development/Pre-production: Data science output has been rolled out/validated across multiple domains/problems effective response example flexible framework heterogeneous knowledge Knowledge graph MERS-CoV Pandemics problem Produce producing related virus related viruses required Research researcher response SARS-CoV SARS-CoV-2 time-consuming while [DOI] 10.1016/j.patter.2020.100155 PMC 바로가기 [Article Type] Article
COVID-19 and the return to head and neck outpatient activity in the United Kingdom: what is the new normal?Short Communication Published on 2020-11-062022-10-31 Journal: European archives of oto-rhino-laryngology : offic [Category] COVID-19, SARS, [키워드] aerosol-generating procedure Air change per hour change clinics COVID-19 cross-sectional equipment flexible head healthcare hour language maintain majority Maxillofacial measure natural ventilation Neck NHS oncologist otolaryngology outpatient clinic participant Patient patient safety patients Protective protocol protocols ranged reduction in Responder Result Risk assessment room salt significant increase speech supplementary material surgical Trust United Kingdom Variation web-based platform [DOI] 10.1007/s00405-020-06458-x PMC 바로가기 [Article Type] Short Communication