Ensuring that COVID-19 research is inclusive: guidance from the NIHR INCLUDE projectResearch Methods Published on 2020-11-052022-10-28 Journal: BMJ Open [Category] COVID-19, Fulltext, SARS, [키워드] affected Analysis Asian benefit black Care Characteristics collected Community comparison COVID-19 COVID-19 research criteria dissemination early stage engage Ensuring Evidence flexible group groups Guidance include Intervention Local multiple long-term conditions NIHR obesity objective Older outcome public health Research Research question researchers statistics & research methods Strong These data Topic Trial [DOI] 10.1136/bmjopen-2020-043634 PMC 바로가기 [Article Type] Research Methods
Supporting SARS-CoV-2 Papain-Like Protease Drug Discovery: In silico Methods and BenchmarkingChemistry Published on 2020-11-052022-10-31 Journal: Frontiers in Chemistry [Category] COVID-19, [키워드] acute respiratory syndrome Analysis approach AutoDock Benchmarking binding site caused comparable coronavirus coronavirus disease COVID-19 database DEKOIS 2.0 docking docking tool drug DrugBank ENhance example flexible generate homology model introduced Ligand ligand-bound manuscript pandemic Papain-like protease peptide-like inhibitor performed PLPro provide reported residue SARS-CoV SARS-CoV-2 sequence identity small molecule submission Supporting Virtual screening virus replication VS X-ray [DOI] 10.3389/fchem.2020.592289 PMC 바로가기 [Article Type] Chemistry
Fast Response to Superspreading: Uncertainty and Complexity in the Context of COVID-19Article Published on 2020-10-272022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, SARS, [키워드] complex complex systems complexity consequence Context contribute coronavirus disease COVID-19 COVID-19 pandemic develop Epidemiology Fast response flexible improvisation interdisciplinary perspectives Intervention long-lasting networks organization pandemic peaked Perspective predict Research response responses risk SARS-CoV-2 second wave Spread superspreading Transdisciplinarity Uncertainty virus [DOI] 10.3390/ijerph17217884 PMC 바로가기 [Article Type] Article
Gender Effect on Political Leaders’ Nonverbal Communicative Structure during the COVID-19 CrisisArticle Published on 2020-10-242022-10-29 Journal: International Journal of Environmental Research an [Category] Coronavirus, SARS, [키워드] analyzed Contact cooperativeness country COVID-19 COVID-19 pandemic crisis develop Effect emotional explain expressions female females FIVE flexible Gender interaction effect leadership male nonverbal communication optimism pandemic political communication profile Severe case significant effect Structure tension [DOI] 10.3390/ijerph17217789 PMC 바로가기 [Article Type] Article
A flexible method for optimising sharing of healthcare resources and demand in the context of the COVID-19 pandemicResearch Article Published on 2020-10-212022-10-28 Journal: PLoS ONE [Category] Coronavirus, MERS, SARS, [키워드] Algorithm approach autonomous Contact COVID-19 COVID-19 pandemic criteria develop feasibility flexible functions geometric healthcare Healthcare system heterogeneous ICU identify indicate intensive care intensive care unit Local local health service National Health Service Patient random resource risk Spain Spanish transfer United Kingdom [DOI] 10.1371/journal.pone.0241027 PMC 바로가기 [Article Type] Research Article
On the use of growth models to understand epidemic outbreaks with application to COVID-19 dataResearch Article Published on 2020-10-202022-10-28 Journal: PLoS ONE [Category] Coronavirus, MERS, SARS, [키워드] applied approach Containment measure containment measures COVID-19 COVID-19 outbreak death rates effort Epidemic estimate flexible growth implementation infections information initial Isolation Italy less outbreak positive reported resulting [DOI] 10.1371/journal.pone.0240578 PMC 바로가기 [Article Type] Research Article
Design, Synthesis and In Vitro Experimental Validation of Novel TRPV4 Antagonists Inspired by Labdane DiterpenesArticle Published on 2020-10-182022-10-30 Journal: Marine Drugs [Category] Coronavirus, MERS, SARS, [키워드] acute respiratory syndrome amide amides/esters antagonist antagonists assays bioactive diterpenes biological activity cellular Compound coronavirus COVID-19 Critical determinant diterpene flexible Infection Labdane labdane scaffold novel nucleus organism oxidized pharmacological pharmacological target plants receptor respiratory diseases SARS-CoV-2 sclareolide selective Structure-activity relationships synthesis terrestrial TRPV1 TRPV4 TRPV4 channel validation variety were assessed widespread [DOI] 10.3390/md18100519 PMC 바로가기 [Article Type] Article
COVID-19 and the call for ‘Safe Hands’: Challenges facing the under-resourced municipalities that lack potable water access – A case study of Chitungwiza municipality, ZimbabweFull Paper Published on 2020-10-162022-10-28 Journal: Water Research X [Category] COVID-19, [키워드] Affect average challenge Chitungwiza conducted country COVID COVID-19 dry tap effective Effectiveness ENhance flexible household hygiene implementation implication IMPROVE include increase individual Intermittent water supply lack less lockdown measure municipality National Novel coronavirus Pandemics per day Prevent reduced Region Regulation resident Safe Safe hands spread of COVID-19 WHO World Health Organisation World Health Organization Zimbabwe [DOI] 10.1016/j.wroa.2020.100074 PMC 바로가기 [Article Type] Full Paper
Modelling COVID 19 in the Basque Country from introduction to control measure responseArticle Published on 2020-10-142022-10-29 Journal: Scientific Reports [Category] COVID-19, MERS, SARS, [키워드] adjusted Analysis approaches assist Asymptomatic calculated Computational biology and bioinformatics country Course COVID 19 COVID-19 develop disease transmission Diseases effective effort epidemiological data flexible force growth growth rate Health health manager Hospital admissions Hospitalized implication information lifted lockdown measure Measures Mild MONITOR National partial lockdown positive predict responses Severe infection shown statistical Systems biology tested the epidemic [DOI] 10.1038/s41598-020-74386-1 PMC 바로가기 [Article Type] Article
The IGNITE trial: Participant recruitment lessons prior to SARS-CoV-2Article Published on 2020-10-092022-11-01 Journal: Contemporary Clinical Trials Communications [Category] COVID-19, [키워드] aerobic assist Brain changed clinical trial Cognition COVID-19 Critical disparity Effect Enrollment exercise flexible Gain Generalizability Health implementation Infection infection rate lifted pandemic participant phase randomization recruitment required SARS-CoV-2 SARS-CoV-2 coronavirus Screen-fail Study design The United States Threats trials [DOI] 10.1016/j.conctc.2020.100666 PMC 바로가기 [Article Type] Article