RpoS Plays a Central Role in the SOS Induction by Sub-Lethal Aminoglycoside Concentrations in Vibrio choleraeRpoS는 Vibrio cholerae에서 치명적이지 않은 아미노글리코사이드 농도에 의한 SOS 유도에서 중심 역할을 합니다Research Article Published on 2013-04-112022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] addressed Aminoglycoside Antibiotic resistance Antibiotics Author Bacteria Bacterial caused cellular mechanism cellular mechanisms CENTRAL Concentration connection conserved corollary different DNA DNA damage DNA damaging E. coli Escherichia coli flow cytometry found Frequency fusion gene transfer Genetic Genome genomic plasticity gram growth guanine horizontal gene Horizontal gene transfer increase in induce induction inhibit inhibitory concentration Klebsiella pneumoniae leads low dose Mutation mutations Other over-expression oxidative oxidative stress oxidative stress response oxidized oxygen paradigm pathogen Pathogens pathway Pathways physiological effect physiological effects physiological response pneumoniae Prevent promoter Protein reactive oxygen specy regulated related role RpoS shown SOS SOS response Stress stress conditions stress response Testing tobramycin transfer V. cholerae Vibrio cholerae [DOI] 10.1371/journal.pgen.1003421 PMC 바로가기 [Article Type] Research Article
Quercetin 7-rhamnoside reduces porcine epidemic diarrhea virus replication via independent pathway of viral induced reactive oxygen speciesResearch Published on 2011-10-042022-10-28 Journal: Virology Journal [Category] Coronavirus, MERS, [키워드] addition antioxidant antiviral activity Course CPE Cytopathic effect DNA fragment DNA fragmentation Effect epidemic diarrhea flow cytometry Hypothesis inactive independent induce Infection investigated NAC pathway PEDV Production quercetin reactive oxygen specy reduce reduced reduction Result ROS Vero Cell virus replication [DOI] 10.1186/1743-422X-8-460 PMC 바로가기 [Article Type] Research
Action Mechanisms of Lithium Chloride on Cell Infection by Transmissible Gastroenteritis CoronavirusResearch Article Published on 2011-05-062022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] Action added Analysis analysis Annexin anti-apoptotic Apoptosis assay bronchitis caspase-3 Cell Cell culture cell lines concerning coronavirus Coronaviruses detected different DNA viruses dose dose-dependent manner effective epidemic diarrhea expression flow cytometry found Genes herpes simplex virus IBV immunofluorescence in vitro indicated Infection infectious inhibit inhibited inhibitory effect initial investigated late stage LiCl lithium Lithium chloride (LiCl mechanism MTT not affected nuclei plaque Post-infection Real-time PCR reported RNA virus RT-PCR staining TGEV Transcription transmissible gastroenteritis virus Treatment vaccinia virus virus virus [DOI] 10.1371/journal.pone.0018669 PMC 바로가기 [Article Type] Research Article
Prolonged depletion of circulating CD4 + T lymphocytes and acute monocytosis after pantropic canine coronavirus infection in dogsArticle Published on 2010-06-152022-11-01 Journal: Virus research [Category] Coronavirus, MERS, [키워드] Alter B cell B cells B lymphocyte baseline level canine Canine coronavirus CD14 CD21 CD4 CD4+ T cell depletion CD8 CD8+ T cells circulating coronavirus Coronavirus infection days post-infection flow cytometry IgM immune infect Infected Infection lymphopenia monocytosis Peripheral blood monocyte Prolonged recovered completely remained returned serum IgG significantly T cell T lymphocyte [DOI] 10.1016/j.virusres.2010.06.006 PMC 바로가기 [Article Type] Article
Endocytosis of the receptor-binding domain of SARS-CoV spike protein together with virus receptor ACE2Article Published on 2008-06-102022-11-01 Journal: Virus research [Category] Coronavirus, [키워드] ACE2 ACE2, angiotensin converting enzyme 2 acute respiratory syndrome Angiotensin converting enzyme 2 (ACE2) binding cells coronavirus demonstrated endocytosis enzyme expressed flow cytometry fusion protein HEK293 cells human IgG1 implication mapped N-glycan N-linked glycosylation Protein purified RBD RBD-Fc RBD, receptor-binding domain receptor Receptor-binding domain (RBD) SARS-CoV SARS-CoV spike protein SARS-CoV, severe acute respiratory syndrome coronavirus severe acute respiratory syndrome coronavirus (SARS-CoV) Spike protein susceptible susceptible cell the RBD the receptor-binding domain the S protein Vaccine viral spike virus receptor [DOI] 10.1016/j.virusres.2008.03.004 PMC 바로가기 [Article Type] Article