A Case of a COVID-19-positive PatientInternal Medicine Published on 2020-04-092022-10-31 Journal: Cureus [Category] COVID-19, [키워드] chills Chloroquine coronavirus cough COVID-19 creating feature Fever fibrosis ground-glass opacity Influenza male positive was tested [DOI] 10.7759/cureus.7608 PMC 바로가기 [Article Type] Internal Medicine
Influenza-associated pneumonia as reference to assess seriousness of coronavirus disease (COVID-19)Rapid Communication Published on 2020-03-192022-10-31 Journal: Eurosurveillance [Category] COVID-19, MERS, SARS, [키워드] approach Cohort Comorbidity comparison coronavirus disease COVID-19 COVID-19 patient creating disease fatality healthcare hospital hospitals intensive care Patient Pneumonia resources SARS-CoV-2 Seriousness of disease severity Transmissibility Ventilation [DOI] 10.2807/1560-7917.ES.2020.25.11.2000258 PMC 바로가기 [Article Type] Rapid Communication
Essential gene deletions producing gigantic bacteria거대 박테리아를 생성하는 필수 유전자 결실Research Article Published on 2019-06-102022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] accelerated Acinetobacter Analysis antibiotic Antibiotics Bacteria Bacterial Bacterial infections blocked Cell cell wall cell wall synthesis cells cleave consequence conserved creating dead dead cell dead cells deleted Deletion eliminating enzyme Essential feature function functions Genetic Giant giant cell giant cells help hydrolysis identify inactivated independent life lysed lytic transglycosylase mutant mutants Mutation natural transformation osmotic overcome overlapping pathogenic pathway peptide peptidoglycan polymerization precursor predicted produced producing required respond responsible resulting sacculus targets the cell the dead Tn-seq transposon Treatment [DOI] 10.1371/journal.pgen.1008195 PMC 바로가기 [Article Type] Research Article
Anti-inflammatory microRNA-146a protects mice from diet-induced metabolic disease항염증성 microRNA-146a는 식이 유발 대사 질환으로부터 생쥐를 보호합니다Research Article Published on 2019-02-152022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] absence adipose Adipose tissue Adiposity administration blockade blood glucose cellular cellular metabolism cellular respiration chronic inflammation Combination contribute Control controls creating Critical demonstrated develop Diabetic diabetic patient diabetic patients diet dysregulated Evidence expressed expression Factor fat genetics Glucose Glycolysis Human identifying Immune cell immune cells increase in Inflammation inflammatory function inflammatory gene inflammatory genes inflammatory pathways influence inhibitor Interaction investigated involved Macrophage macrophages mechanism metabolic disease metabolic pathway metabolic pathways metabolic processe metabolic processes metabolism mice microRNA miR-146 miRNA mTOR NF-κB NF-κB activation obese obesity pathway phenotype Phenotypes potential therapeutic target Prevent Pro-inflammatory genes PROTECT protective role provide Rapamycin reduced regulate regulated Regulatory represse Research RNA-sequencing shown Symptom tissue tissue macrophage Traf6 weight gain wild-type [DOI] 10.1371/journal.pgen.1007970 PMC 바로가기 [Article Type] Research Article
Euclidean Distance Analysis Enables Nucleotide Skew Analysis in Viral GenomesResearch Article Published on 2018-10-302022-10-31 Journal: Computational and Mathematical Methods in Medicine [Category] Coronavirus, [키워드] addition Analysis characteristic Clusters coronavirus creating dissimilarity distance Euclidean distance form genome regions HIV-1 indicated normalized nucleotide nucleotide substitution Quantitative related virus RNA genomes sequence similarity single-stranded skew time-consuming viral genome viral RNA genome virus virus genomes virus isolate window [DOI] 10.1155/2018/6490647 PMC 바로가기 [Article Type] Research Article
How Do the First Days Count? A Case Study of Qatar Experience in Emergency Risk Communication during the MERS-CoV OutbreakCase Report Published on 2017-12-192022-10-30 Journal: International Journal of Environmental Research an [Category] Coronavirus, [키워드] activity CERC characterized collected communication contributed coordination Course creating crisis Day develop Emergency emergency risk communication Epidemic ERC event experience Frame help information maintain management media MERS MERS-CoV Middle East outbreak performed provide public health authorities Qatar released Research risk the epidemic [DOI] 10.3390/ijerph14121597 PMC 바로가기 [Article Type] Case Report
Polymerase cross-linking spiral reaction (PCLSR) for detection of African swine fever virus (ASFV) in pigs and wild boarsArticle Published on 2017-02-152022-10-29 Journal: Scientific Reports [Category] Coronavirus, [키워드] African Blood cDNA classical collected complementary complex structures conducted creating cross-reaction DNA epidemic diarrhea examined Fever fluorescent gel electrophoresis gene sequence outbreak PEDV Plasmid polymerase primer Primers reached Real-time PCR reproductive selected sensitivity sequence spiral Surveillance SYBR Green I syndrome tissue sample virus [DOI] 10.1038/srep42903 PMC 바로가기 [Article Type] Article
Distinct Prion Domain Sequences Ensure Efficient Amyloid Propagation by Promoting Chaperone Binding or Processing In Vivo고유한 프리온 도메인 서열은 생체 내 샤페론 결합 또는 처리를 촉진하여 효율적인 아밀로이드 증식을 보장합니다Research Article Published on 2016-11-042022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] acting aggregate Alter Amino acid amyloid assembly binding change chaperone chaperones complementary composed conformation conformational conformational flexibility contribute creating efficient element elements Ensure functional in vitro in vivo inheritance Interaction maintain mechanism molecular observation occur open persistence physical physical properties predict prion processing promote Promoting Propagation Protein Protein misfolding Proteins proximal PSI question Regulation required resulting sequence Spectrum stability Transmission yeast [DOI] 10.1371/journal.pgen.1006417 PMC 바로가기 [Article Type] Research Article
Infectious diseases epidemic threats and mass gatherings: refocusing global attention on the continuing spread of the Middle East Respiratory syndrome coronavirus (MERS-CoV)Commentary Published on 2016-09-072022-10-28 Journal: BMC Medicine [Category] Coronavirus, MERS, [키워드] Community condition Control coronavirus country creating death disease Diseases Donor Ebola virus emerging disease Epidemic Epidemic transmission Epidemics game global public health Hajj Infectious disease Infectious diseases International Kingdom Korean mass Mass gathering MERS case MERS-CoV middle Middle East occurred outbreak resource respiratory respiratory syndrome coronavirus Rio Saudi Arabia South South Korea Spread Surveillance syndrome the WHO threat Threats Transmission West WHO World Health Organization Zika virus [DOI] 10.1186/s12916-016-0686-3 PMC 바로가기 [Article Type] Commentary
Pathosphere.org: pathogen detection and characterization through a web-based, open source informatics platformSoftware Published on 2015-12-292022-10-27 Journal: BMC Bioinformatics [Category] Coronavirus, [키워드] addition Analysis analyzed annotation bioinformatics Biological center Chemical Community complex coronavirus creating detect Government homology Host identify Illumina Infectious disease Ion iterative NCBI Next-generation sequencing NGS pathogen pathogen detection platform provide Result sequence sequenced Sequencing supplementary material Support tested the United State utility variety zoonotic [DOI] 10.1186/s12859-015-0840-5 PMC 바로가기 [Article Type] Software