He-Jie-Shen-Shi Decoction as an Adjuvant Therapy on Severe Coronavirus Disease 2019: A Retrospective Cohort and Potential Mechanistic Study
Pharmacology
[키워드] acute respiratory distress
acute respiratory distress syndrome
adjuvant
Analysis
ARDS
Bupleurum
can be used
CCL2
Chinese
Clinical efficacy
Clinical practice
combination therapy
component
composed
conducted
coronavirus disease
Coronavirus disease 2019
COVID-19
Cytoscape
Decoction
Effect
endothelial
Fever
GeneCard
Glycyrrhiza uralensis
growth factor
he-jie-shen-shi decoction
IL1B
Inflammatory response
inheritance
inhibiting viral replication
involved
KEGG
Kyoto
Ligand
Lung injury
Man
MAPK
MAPK signaling
MAPK3
mechanism
mechanisms
Medicine
monotherapy
Necrosis
Negative conversion
network
network pharmacology
nine
notable
nucleic acid
oxidative stress
p53
pathway
Pathways
Patient
Pharmacology
Pinellia ternata
Potential
PPI
predict
Protein
Protein–protein interaction
PTGS2
receptor
required
Result
retrospective cohort study
screened
Scutellaria baicalensis
selected
severe COVID-19
shown
suggested
syndrome
System
T cell receptor
target
TCMSP
therapeutic
therapy
TNF
Toll-like receptor
Tongji Hospital
TP53
Traditional
Traditional Chinese medicine
treat
Vascular
VEGF
VEGFA
Wuhan
[DOI] 10.3389/fphar.2021.700498 PMC 바로가기 [Article Type] Pharmacology
[DOI] 10.3389/fphar.2021.700498 PMC 바로가기 [Article Type] Pharmacology